Find all hotels by Motel 6 in Otay Mesa West, CA from $68

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Compare rooms and suites by Motel 6 in Otay Mesa West with rates, reviews, and availability. Most hotels are fully refundable.

Lobby
Motel 6 San Ysidro, CA - San Diego - Border

Motel 6 San Ysidro, CA - San Diego - Border

2.0 star property
San Ysidro
7.0 out of 10, Good, (1468)
"exceptional "
United States
Clarissa
$66 nightly
The price is $75
Jan 4 - Jan 5, 2026
Total with taxes and fees
Motel 6 San Ysidro, CA - San Diego - Border
Outdoor pool, open 9:00 AM to 9:00 PM, pool umbrellas, sun loungers
Motel 6 El Cajon, CA - San Diego

Motel 6 El Cajon, CA - San Diego

2.0 star property
El Cajon
7.4 out of 10, Good, (1453)
"My stay here was pretty cool"
United States
Rana
$69 nightly
The price is $77
Dec 9 - Dec 10
Total with taxes and fees
Motel 6 El Cajon, CA - San Diego
Lobby
Motel 6 Chula Vista, CA - San Diego

Motel 6 Chula Vista, CA - San Diego

2.0 star property
Chula Vista
6.0 out of 10, (1785)
"yes it was , i love here"
United States
david
$66 nightly
The price is $74
Dec 9 - Dec 10
Total with taxes and fees
Motel 6 Chula Vista, CA - San Diego
Desk, free WiFi, bed sheets
Motel 6 San Diego, CA - Downtown

Motel 6 San Diego, CA - Downtown

2.0 star property
Downtown San Diego
6.2 out of 10, (1242)
"Great space and ease of access"
United States
Darren
$59 nightly
The price is $68
Dec 9 - Dec 10
Total with taxes and fees
Motel 6 San Diego, CA - Downtown
Outdoor pool
Motel 6 San Diego, CA - Hotel Circle - Mission Valley

Motel 6 San Diego, CA - Hotel Circle - Mission Valley

2.0 star property
Mission Valley
6.8 out of 10, (1478)
"Great location but the hotel needs a deep cleaning. "
United States
Michael
$73 nightly
The price is $84
Dec 15 - Dec 16
Total with taxes and fees
Motel 6 San Diego, CA - Hotel Circle - Mission Valley
Outdoor pool
Motel 6 San Diego Airport - Harbor

Motel 6 San Diego Airport - Harbor

2.0 star property
Downtown San Diego
7.0 out of 10, Good, (1005)
"Had a great relaxful evening. Staff was awesome and helpful."
United States
Joel
$62 nightly
The price is $70
Dec 14 - Dec 15
Total with taxes and fees
Motel 6 San Diego Airport - Harbor
Exterior
Motel 6 San Diego, CA - Southbay

Motel 6 San Diego, CA - Southbay

2.0 star property
Nestor
7.4 out of 10, Good, (1001)
"Nice friendly staff and manager clean rooms "
United States
Christopher
$72 nightly
The price is $81
Dec 9 - Dec 10
Total with taxes and fees
Motel 6 San Diego, CA - Southbay
Restaurant
Motel 6 San Diego, CA - North

Motel 6 San Diego, CA - North

2.0 star property
Clairemont
6.8 out of 10, (1003)
"Great stay, especially for the price. "
United States
Jake
$83 nightly
The price is $94
Dec 31 - Jan 1, 2026
Total with taxes and fees
Motel 6 San Diego, CA - North
Blackout drapes, free WiFi, bed sheets
Motel 6 La Mesa, CA

Motel 6 La Mesa, CA

2.0 star property
La Mesa
7.2 out of 10, Good, (1001)
"Easy parking, clean, nice staff, safe"
United States
Martha
$90 nightly
The price is $99
Dec 14 - Dec 15
Total with taxes and fees
Motel 6 La Mesa, CA
Blackout drapes, free WiFi, bed sheets
Motel 6 La Mesa, CA - San Diego

Motel 6 La Mesa, CA - San Diego

2.0 star property
La Mesa
7.4 out of 10, Good, (976)
"Best Motel 6 I’ve ever been too! Clean marbel showers and comfortable beds!"
United States
Izaiah
$86 nightly
The price is $95
Dec 11 - Dec 12
Total with taxes and fees
Motel 6 La Mesa, CA - San Diego
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Otay Mesa West Hotel Reviews

Wyndham San Diego Bayside

Wyndham San Diego Bayside

10/10 Excellent
"Yes"
Patricia 1-night trip
Posted 23 hours ago
Wyndham San Diego Bayside

Find out more about Otay Mesa West

Otay Mesa West, San Diego County Hotel Guide

Otay Mesa West is 11 miles from San Diego County's downtown.

San Diego County is home to the San Diego State University, the San Diego Zoo and the Balboa Park.

If you're in need of some caffeine to help you get through the day, Starbucks is among the best places in Otay Mesa West to enjoy a fix. Still hungry? Giant New York Pizza is also close and dishes up a good range of meals. Are you up for a drink? Cap off an enjoyable day with an icy beer or a satisfying red at Bobar Liquor.

Accommodation Options Near Otay Mesa West

For those keen on coming to Otay Mesa West, you can stay in San Ysidro, a neighborhood which is 2 miles south of the center of Otay Mesa West. Explore Expedia's San Ysidro hotels guide to find great accommodation options such as the Rodeway Inn and Quality Inn & Suites Near The Border. You could also choose to try South Bay hotels, such as the Holiday Inn Express San Diego South - Chula Vista and Holiday Inn Express San Diego South - National City. South Bay is located 3 miles to the northeast of the center of Otay Mesa West.

Check out our San Diego County hotels page for quality places to stay in Otay Mesa West and beyond. If you want to be inspired about things to see and do there, don’t miss our San Diego County vacation travel guide.

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