Picayune Vacations from $460

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Your Picayune Vacation

Enjoy unforgettable adventures when you lock in a vacation package to Picayune. Whether you're a history buff, foodie or just a traveler who loves discovering new places, there's something for everyone in this exciting city. Crosby Aboretum and Millbrook Country Club are among the must-see sights to check out during your trip to Picayune. A couple of clicks is all it takes to build a tailored Picayune vacation on Expedia.

The Latest Picayune vacation packages

Price found within the past 48 hours. Click for updated prices.
Slip Away at Harbor Landing

Slip Away at Harbor Landing

2 out of 5
Price was $556, price is now $460 per person
$460
per person
Jan 27 - Jan 30
found 1 day ago
Roundtrip non-stop flight included
Columbus (CMH) to Gulfport (GPT)
No reviews

The Meridian | Walkable. Coastal. Elevated.

The Meridian | Walkable. Coastal. Elevated.

2 out of 5
Price was $867, price is now $687 per person
$687
per person
Jan 5 - Jan 8
found 1 day ago
Roundtrip non-stop flight included
Columbus (CMH) to Gulfport (GPT)
10/10 Exceptional! (1 review)
This house was a last-minute booking and WOW were we thrilled with it! It is absolutely gorgeous! The entire house was spotless, and the furnishings were beautiful. But the real star of the show for us was the outdoor spaces. The screen porch was perfect for morning coffee. The lavish back porch was the perfect spot to relax and watch the games. We even took a short walk to the Blue Dog for breakfast one morning. Finally, the hosts were exceptionally responsive to all our questions/requests. Definitely a great find!

Reviewed on Oct 15, 2026

The Downtown Cedar

The Downtown Cedar

2 out of 5
Price was $649, price is now $531 per person
$531
per person
Jan 27 - Jan 30
found 1 day ago
Roundtrip non-stop flight included
Columbus (CMH) to Gulfport (GPT)
9/10 Wonderful! (2 reviews)
Nice little home that’s located close to downtown. It was great for what we needed. It is not handicapped friendly, tho. Currently (May 2026), there is a high 1-step front door entry that could be easily fixed with a sturdy second platform step up from the nice front porch to make it easier to get in and out. It also has a nice upgraded single bathroom, but the claw tub is deep without a handrail and no suction in-tub bath mat to keep a person from falling. The rain shower is great however. Kitchen has good amenities, and the dining and living room areas are nice. Good amount of seating, large TV. Overall, for an older home, it’s nice and, a big plus, it doesn’t have a musty smell.

Reviewed on Jun 3, 2026

Landing Furnished Apartments Ocean Springs - Gulf Hills

Landing Furnished Apartments Ocean Springs - Gulf Hills

3 out of 5
Price was $851, price is now $717 per person
$717
per person
Dec 29 - Jan 1
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Gulfport (GPT)
10/10 Exceptional! (1 review)
Best than I could’ve ever expected.

Reviewed on Jul 11, 2026

The Pass Picture Book

The Pass Picture Book

3 out of 5
Price was $569, price is now $484 per person
$484
per person
Jan 5 - Jan 8
found 1 day ago
Roundtrip non-stop flight included
Columbus (CMH) to Gulfport (GPT)
10/10 Exceptional! (1 review)

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Stay near popular Picayune attractions

Crosby Arboretum

7.8/10 (8 reviews)
The Crosby Arboretum showcases native Mississippi ecosystems across pine savannas, wetlands, and woodlands. Experience the award-winning Pinecote Pavilion and follow trails through the Pearl River Basin's natural heritage.
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Picayune Hotel Deals

Holiday Inn Express Picayune-Stennis Space Center by IHG

Holiday Inn Express Picayune-Stennis Space Center by IHG

2.5 out of 5
1001 Dauphin Street Picayune MS
Fully refundable
$107 nightly
The price is $117 total per night from Dec 3 to Dec 4
$117 total
Dec 3 - Dec 4
Total with taxes and fees
Holiday Inn Express Picayune-Stennis Space Center by IHG
Days Inn by Wyndham Picayune

Days Inn by Wyndham Picayune

2 out of 5
450 S Lofton Avenue Picayune MS
Fully refundableReserve now, pay when you stay
$55 nightly
The price is $60 total per night from Nov 10 to Nov 11
$60 total
Nov 10 - Nov 11
Total with taxes and fees
6.2/10 (395 reviews)
"On arrival, my room had a heavy bleach smell in the room, the floors were sticky, and television did not work. I requested a room change and it was drab and patches in the wall where repairs had been made. Bed frame had old springs which screeched when you sat on it."

Reviewed on Oct 28, 2026

Days Inn by Wyndham Picayune
Hollywood Casino Gulf Coast

Hollywood Casino Gulf Coast

3.5 out of 5
711 Hollywood Blvd Bay St Louis MS
Fully refundableReserve now, pay when you stay
$57 nightly
The price is $62 total per night from Nov 25 to Nov 26
$62 total
Nov 25 - Nov 26
Total with taxes and fees
Hollywood Casino Gulf Coast
See all 1,048 properties in Picayune
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Picayune Vacation Packages

Picayune Essential Information

Language
English
Currency
U.S dollars
Population
10,700
Max Temp Winter
65ºF
Max Temp Summer
90ºF
Top Sights
Crosby Aboretum and Millbrook Country Club

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Frequently asked questions

How much does a Picayune vacation package cost?
Offering great value package deals from $460 on Expedia, you'll be surprised at how little a vacation to Picayune costs! Our packages make travel planning easier and save you more.
What are the cheapest months to go to Picayune?
If you're looking to score a cheap Picayune vacation package, consider planning a trip in July, September and October. You're likely to find better rates on flights and hotels during these months — perfect for a budget-friendly break.
How many days is enough for Picayune?
Usually, a handful of days is enough to visit the major sights during your Picayune vacation. But if you want to have time to unwind or go on day trips, consider extending your itinerary.
How to find the best Picayune package deals?
Landing a cheap Picayune package deal is a cinch with Expedia. Once you've entered your destination and preferred dates under our "Packages" tab, set your budget range, add a few filters and see what's available. You can tailor your search by "Amenities," "Property type," "Popular locations" and more. Sort the results by "Price: low to high" to discover the most wallet-friendly Picayune package deals. Want a simple trick to score even more savings? Have some flexibility with your departure dates and consider traveling on a weekday, when prices are often lower.
Is it cheaper to book a Picayune vacation as a package?
You can enjoy significant savings on your next Picayune getaway by booking a customized vacation package. Click on the "Package" heading, then enter your destination and travel dates to see the best hotel prices and airfares. Bundling can save travelers hundreds of dollars. Consider adding a rental car and you may score a better deal.
When to book a vacation package to Picayune?
If you've got your Picayune vacation dates confirmed, book early to snap up some terrific deals. With Expedia, you can generally reserve some flights up to a year in advance. Prefer spur-of-the-moment adventures? Our last-minute deals are perfect for quick escapes.
Does Expedia offer Book Now, Pay Later Picayune vacation packages?
Jet off on your dream trip to Picayune with help from Expedia's Book Now, Pay Later vacations. No need to scrimp and save or wait until your next paycheck — we've partnered with online lender Affirm to give you financial flexibility. Our vacation packages with payment plans mean you can split the cost across 3, 6 or 12 months. With no late payment fees or hidden charges, it's easy to budget for your trip and snap up bargains before they sell out.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.