Picayune Vacations from $110

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Your Picayune Vacation

Enjoy unforgettable adventures when you lock in a vacation package to Picayune. Whether you're a history buff, foodie or just a traveler who loves discovering new places, there's something for everyone in this exciting city. Crosby Aboretum and Millbrook Country Club are among the must-see sights to check out during your trip to Picayune. A couple of clicks is all it takes to build a tailored Picayune vacation on Expedia.

The Latest Picayune vacation packages

Price found within the past 48 hours. Click for updated prices.
Country Inn & Suites by Radisson, Biloxi-Ocean Springs, MS

Country Inn & Suites by Radisson, Biloxi-Ocean Springs, MS

2.5 out of 5
Price was $132, price is now $110 per person
$110
per person
Jan 6 - Jan 8
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Gulfport (GPT)
6.6/10 (1,005 reviews)
I stay here anytime I stay at a hotel and it is always clean and the girl at the front desk is ALWAYS so friendly and helpful. I highly recommend country inn and suites!

Reviewed on Nov 23, 2025

Centennial Plaza Resort Gulfport

Centennial Plaza Resort Gulfport

2.5 out of 5
Price was $250, price is now $185 per person
$185
per person
Jan 6 - Jan 8
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Gulfport (GPT)
9.2/10 Wonderful! (1,001 reviews)
Every was very nice.

Reviewed on Nov 9, 2025

The Inn at Long Beach

The Inn at Long Beach

3 out of 5
Price was $576, price is now $460 per person
$460
per person
Feb 5 - Feb 8
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Gulfport (GPT)
9.6/10 Exceptional! (1,003 reviews)
Great place next to the beach.

Reviewed on Dec 1, 2025

Holiday Inn Express Picayune-Stennis Space Center by IHG

Holiday Inn Express Picayune-Stennis Space Center by IHG

2.5 out of 5
Price was $233, price is now $193 per person
$193
per person
Feb 2 - Feb 5
found 21 hours ago
Roundtrip flight included
Atlanta (ATL) to Gulfport (GPT)
9/10 Wonderful! (635 reviews)
I have 3 requirements comfortable bed, decent coffee, and shower with lots of hot water. I had all three. Everything was clean and in good condition. My only complaint was the very sparse breakfast. Seemed there were more things out of more things out of stock than available.

Reviewed on Nov 26, 2025

Courtyard by Marriott Biloxi North/D'Iberville

Courtyard by Marriott Biloxi North/D'Iberville

3 out of 5
Price was $184, price is now $152 per person
$152
per person
Jan 6 - Jan 8
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Gulfport (GPT)
9.2/10 Wonderful! (1,001 reviews)
Room was clean , staff were great! Awesome hotel.

Reviewed on Nov 20, 2025

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Discover the most popular places to visit in Picayune

Millbrook Country Club

Enjoy a round of golf in Picayune at Millbrook Country Club. Wander the riverfront in this family-friendly area.

Millbrook Country Club

Picayune Hotel Deals

Holiday Inn Express Picayune-Stennis Space Center by IHG

Holiday Inn Express Picayune-Stennis Space Center by IHG

2.5 out of 5
1001 Dauphin Street Picayune MS
Fully refundable
$95 nightly
The price is $104 total per night from Dec 15 to Dec 16
$104 total
Dec 15 - Dec 16
Total with taxes and fees
8.8/10 Excellent! (638 reviews)
I have 3 requirements comfortable bed, decent coffee, and shower with lots of hot water. I had all three. Everything was clean and in good condition. My only complaint was the very sparse breakfast. Seemed there were more things out of more things out of stock than available.

Reviewed on Nov 26, 2025

Holiday Inn Express Picayune-Stennis Space Center by IHG
Days Inn by Wyndham Picayune

Days Inn by Wyndham Picayune

2 out of 5
450 S Lofton Avenue Picayune MS
Fully refundableReserve now, pay when you stay
$55 nightly
The price is $60 total per night from Dec 4 to Dec 5
$60 total
Dec 4 - Dec 5
Total with taxes and fees
6/10 (352 reviews)
Great stay!
The pre-check in made the physical check in super fast. The staff was cery friendly, and the room was clean.

Reviewed on Oct 7, 2025

Days Inn by Wyndham Picayune
Heritage Inn Picayune

Heritage Inn Picayune

2 out of 5
1122 Memorial Blvd. Picayune MS
$70 nightly
The price is $76 total per night from Jan 1 to Jan 2
$76 total
Jan 1 - Jan 2, 2026
Total with taxes and fees
8.2/10 Very Good! (284 reviews)
The front desk manager is phenomenal. He addressed all my needs and what I thought was absolutely fantastic is that he brought the Wi-Fi password code to my room because I didn’t have a pin to write it down. I will definitely stay here again.

Reviewed on Nov 9, 2025

Heritage Inn Picayune
See all 1,020 properties in Picayune
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Picayune Vacation Packages

Picayune Essential Information

Language
English
Currency
U.S dollars
Population
10,700
Max Temp Winter
65ºF
Max Temp Summer
90ºF
Top Sights
Crosby Aboretum and Millbrook Country Club

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Frequently asked questions

How much does a Picayune vacation package cost?
Offering great value package deals from $110 on Expedia, you'll be surprised at how little a vacation to Picayune costs! Our packages make travel planning easier and save you more.
What are the cheapest months to go to Picayune?
If you're looking to score a cheap Picayune vacation package, consider planning a trip in July, September and October. You're likely to find better rates on flights and hotels during these months — perfect for a budget-friendly break.
How many days is enough for Picayune?
Usually, a handful of days is enough to visit the major sights during your Picayune vacation. But if you want to have time to unwind or go on day trips, consider extending your itinerary.
How to find the best Picayune package deals?
Landing a cheap Picayune package deal is a cinch with Expedia. Once you've entered your destination and preferred dates under our "Packages" tab, set your budget range, add a few filters and see what's available. You can tailor your search by "Amenities," "Property type," "Popular locations" and more. Sort the results by "Price: low to high" to discover the most wallet-friendly Picayune package deals. Want a simple trick to score even more savings? Have some flexibility with your departure dates and consider traveling on a weekday, when prices are often lower.
Is it cheaper to book a Picayune vacation as a package?
You can enjoy significant savings on your next Picayune getaway by booking a customized vacation package. Click on the "Package" heading, then enter your destination and travel dates to see the best hotel prices and airfares. Bundling can save travelers hundreds of dollars. Consider adding a rental car and you may score a better deal.
When to book a vacation package to Picayune?
If you've got your Picayune vacation dates confirmed, book early to snap up some terrific deals. With Expedia, you can generally reserve some flights up to a year in advance. Prefer spur-of-the-moment adventures? Our last-minute deals are perfect for quick escapes.
Does Expedia offer Book Now, Pay Later Picayune vacation packages?
Jet off on your dream trip to Picayune with help from Expedia's Book Now, Pay Later vacations. No need to scrimp and save or wait until your next paycheck — we've partnered with online lender Affirm to give you financial flexibility. Our vacation packages with payment plans mean you can split the cost across 3, 6 or 12 months. With no late payment fees or hidden charges, it's easy to budget for your trip and snap up bargains before they sell out.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.