Find Vacation Homes in Pike County, MO from $155

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Our top choices for Pike County vacation homes

Historic brick 2-bedroom house in downtown Hannibal with off street parking WiFi

Historic brick 2-bedroom house in downtown Hannibal with off street parking WiFi
Hannibal
9.6 out of 10, Exceptional, (30)
"Wonderful historic property. Beautiful and well kept. Absolutely loved this place "
United States
Randy F.
$155 nightly
The price is $155
Dec 14 - Dec 15
Total with taxes and fees
Historic brick 2-bedroom house in downtown Hannibal with off street parking WiFi

The John Sydney House - Family and Pet Friendly Historic Home Downtown

The John Sydney House - Family and Pet Friendly Historic Home Downtown
Hannibal
9.0 out of 10, Wonderful, (8)
"Beautiful, tastefully decorated and well stocked historic home within walking distance of tourist sites and restaurants. We were in town for a wedding and we truly enjoyed our stay. Great front porch and back patio."
United States
Susan C.
$203 nightly
The price is $223
Dec 15 - Dec 16
Total with taxes and fees
The John Sydney House - Family and Pet Friendly Historic Home Downtown

“Peaceful Retreat” @ MTL

“Peaceful Retreat” @ MTL
Monroe City
10.0 out of 10, Exceptional, (103)
"Beautiful property with gracious hosts. As close to Indian creek marina as you can be. "
United States
Kevin S.
“Peaceful Retreat” @ MTL

Peaceful, Country Cottage with Open Floor Plan

Peaceful, Country Cottage with Open Floor Plan
Quincy
10.0 out of 10, Exceptional, (210)
"Clean and airy secluded except for semis on road but very nice"
United States
Curt M.
$233 nightly
The price is $247
Dec 14 - Dec 15
Total with taxes and fees
Peaceful, Country Cottage with Open Floor Plan

Charming 2-bedroom house at Mark Twain Lake

Charming 2-bedroom house at Mark Twain Lake
Stoutsville
9.8 out of 10, Exceptional, (22)
"The accommodation was cozy. Furnishings are updated and clean. Host was friendly and easy to communicate with. Great place to stay. "
United States
Mark L.
Charming 2-bedroom house at Mark Twain Lake

Gorgeous Victorian with Seasonal Pool , sleeps 8, pet friendly close to downtown

Gorgeous Victorian with Seasonal Pool , sleeps 8, pet friendly close to downtown
Hannibal
10.0 out of 10, Exceptional, (9)
"It was very cozy and well stocked and organized as well! Neat experience to stay in a historic home like this! "
United States
Ashley S.
$341 nightly
The price is $386
Dec 14 - Dec 15
Total with taxes and fees
Gorgeous Victorian with Seasonal Pool , sleeps 8, pet friendly close to downtown

Vibey home a few blocks from downtown Hannibal

Vibey home a few blocks from downtown Hannibal
Hannibal
9.6 out of 10, Exceptional, (10)
"The house was great and clean and very nice. The host very responsive. "
United States
Natalie M.
$249 nightly
The price is $281
Dec 14 - Dec 15
Total with taxes and fees
Vibey home a few blocks from downtown Hannibal

Family-Friendly Home. Sleeps 14. Just minutes away from Mark Twain Lake.

Family-Friendly Home. Sleeps 14. Just minutes away from Mark Twain Lake.
Perry
10.0 out of 10, Exceptional, (13)
"Great place to stay for family fishing trip "
United States
Martin M.
Family-Friendly Home. Sleeps 14. Just minutes away from Mark Twain Lake.

Historic Main Street Cottage

Historic Main Street Cottage
Troy
10.0 out of 10, Exceptional, (36)
"Was in town for an event, it was in walking distance of the down town. Super cute and clean, just loved staying there. Definitely recommend!!"
United States
Kelsey K.
Historic Main Street Cottage

The Chicken Coop on Highway H

The Chicken Coop on Highway H
Troy
10.0 out of 10, Exceptional, (17)
"Great place to stay. Beautiful decor. Peaceful, relaxing, great set up, welcoming. Loved the decor. "
United States
Paul G.
The Chicken Coop on Highway H

Mark Twain lake getaway at Blue Lagoon!

Mark Twain lake getaway at Blue Lagoon!
Monroe City
10.0 out of 10, Exceptional, (33)
"Excellent property! "
United States
Nick B.
Mark Twain lake getaway at Blue Lagoon!

Modern and comfy home five minutes from downtown

Modern and comfy home five minutes from downtown
Hannibal
10.0 out of 10, Exceptional, (21)
"It was such a clean and cute little place to stay. We enjoyed staying there. The back patio was a wonderful place to sit with coffee and read in the morning."
United States
MaryY
Modern and comfy home five minutes from downtown

Hannibal House ~ Walking Distance From Historic District

Hannibal House ~ Walking Distance From Historic District
Hannibal
8.4 out of 10, Very Good, (47)
"It was so close to everything. We greatly enjoyed our stay."
United States
Karla R.
Hannibal House ~ Walking Distance From Historic District

Cozy 3 bed, 2 bath home close to historic downtown Hannibal

Cozy 3 bed, 2 bath home close to historic downtown Hannibal
Hannibal
10.0 out of 10, Exceptional, (47)
"Great place, very clean"
United States
Bob C.
Cozy 3 bed, 2 bath home close to historic downtown Hannibal

Admiral Fuqua House - Large downtown Hannibal Home

Admiral Fuqua House - Large downtown Hannibal Home
Hannibal
9.6 out of 10, Exceptional, (39)
"Fun Fourth of July Weekend!Perfect location for holiday event!"
United States
Betty M.
Admiral Fuqua House - Large downtown Hannibal Home

The Indigo House- Located in the heart of Historic Hannibal, Missouri

The Indigo House- Located in the heart of Historic Hannibal, Missouri
Hannibal
10.0 out of 10, Exceptional, (52)
"What a comfortable home, with lots of space and character and a great location. We came back after our first stay, and plan to come back again."
United States
Monie H.
The Indigo House- Located in the heart of Historic Hannibal, Missouri

Newly Built Shouse Near Mark Twain Lake!

Newly Built Shouse Near Mark Twain Lake!
Monroe City
10.0 out of 10, Exceptional, (4)
"We had a great stay here! Perfect place for a weekend get away. A quick drive to the marina and having the stocked pond was entertainment for the evening! Great and responsive hosts as well, highly recommend! "
United States
Randall F.
$297 nightly
The price is $297
Dec 14 - Dec 15
Total with taxes and fees
Newly Built Shouse Near Mark Twain Lake!

A real charmer built in 1915 , pet friendly , located next to Mark Twain lake.

A real charmer built in 1915 , pet friendly , located next to Mark Twain lake.
Perry
10.0 out of 10, Exceptional, (26)
"Pet friendly. Great stay. Family friendly. "
United States
Patricia B.
A real charmer built in 1915 , pet friendly , located next to Mark Twain lake.

The Yellow Rose Historic Home

The Yellow Rose Historic Home
Louisiana
9.8 out of 10, Exceptional, (12)
"We are 7 sisters aged 50-76. We had a wonderful stay at the Yellow Rose. This beautiful old home had rooms and beds for all of us. Would definitely stay here again"
United States
Ellen B.
$308 nightly
The price is $316
Dec 14 - Dec 15
Total with taxes and fees
The Yellow Rose Historic Home

Experience Hannibal, MO from this historic home built in 1844

Experience Hannibal, MO from this historic home built in 1844
Hannibal
10.0 out of 10, Exceptional, (17)
"Great place. We enjoyed the history of the home and the location."
United States
Grant E.
$298 nightly
The price is $336
Dec 14 - Dec 15
Total with taxes and fees
Experience Hannibal, MO from this historic home built in 1844
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Pike County Hotel Reviews

Find out more about Pike County

Booking Tips to Find the Best Pike County Vacation Homes


How much does it cost to rent a vacation home in Pike County?

You can find incredible Pike County vacation homes for all types of budgets: between $155 and $386 per night. The more amenities the rental has, and its proximity to popular places, the higher the price.


What is the best time to stay in a vacation home in Pike County?

If you are looking for a great deal on your vacation home in Pike County, consider visiting in , when prices are usually cheaper.


How many vacation homes are available for rent in Pike County?

There are 39 rental houses to choose from for your trip. You’ll find holiday homes located throughout the city, near sightseeing spots, and close to local nature areas.


How do I find the best deal for a vacation home in Pike County?

Begin by entering your trip dates to see what type of Pike County rental houses are available. Use the map to zoom closer into the areas or zoom out to include more locations. Use the filters on the left side of your search results to narrow down by star rating, price, number of bedrooms, amenities, and more—Expedia makes it easy to score the best deal for your budget.


Why should I rent a vacation home in Pike County?

Booking Pike County vacation home rentals is the perfect way to spend a vacation because of the privacy, variety of amenities, and comfort you’ll have in your own space.


What amenities are available in a private vacation home?

When thinking about what you want in your Pike County rental house, dream big! Depending on your budget and the area, you’ll find amenities like a private pool, hot tub, free parking, fully-equipped kitchen, in-home washer and dryer, Wi-Fi, and a beautiful view or easy access to local sightseeing spots. You can even filter your search results by accessibility to ensure that everyone in your party will be comfortable.


Why should I book a vacation home with Expedia?

Expedia has some of the best selection and deals on available vacation homes in the area—and all in one place. We reward you with members points back on every booking and ensure you get the right accommodation for the best price. And you’ll save big when you bundle your travel together, like booking a car rental in Pike County along with your vacation property, into a Pike County vacation package.


Can I cancel my vacation home with Expedia?

Some accommodations are free to cancel and refundable if done so by a specific date, while others may be non-refundable. To make sure that you can get your money back on cancellations, use the “free cancellation” filter during your search. Contact our customer service portal if you need help.

Pike County Vacation Homes information

Number of reviews
750
Accommodation
39 Vacation Homes
Lowest Price
$155
Highest Price
$386

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