A coastal city with a marina, a bridge, and a mix of residential and commercial buildings.

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Check availability on San Marco Luxury Hotels

Our top choices for San Marco luxury hotels

1. Hampton Inn Jacksonville-Downtown-I-95

Hampton Inn Jacksonville-Downtown-I-95
4.0 star property
Downtown Jacksonville
8.0 out of 10, Very Good, (1,011 reviews)
$106 nightly
The price is $120
Oct 4 - Oct 5
Total with taxes and fees
Hampton Inn Jacksonville-Downtown-I-95

2. Hyatt Regency Jacksonville

Hyatt Regency Jacksonville
4.0 star property
Downtown Jacksonville
9.0 out of 10, Wonderful, (1,798 reviews)
  • cleanliness
    Riverfront luxury offers rooftop pool, three restaurants, and immaculate views of Jacksonville's waterfront.
$186 nightly
The price is $211
Sep 18 - Sep 19
Total with taxes and fees
Hyatt Regency Jacksonville

3. Marriott Jacksonville Downtown

Marriott Jacksonville Downtown
4.0 star property
Downtown Jacksonville
8.4 out of 10, Very Good, (1,000 reviews)
  • cleanliness
    Upscale downtown retreat features city vistas, plush beds, premium toiletries, and pool access.
$135 nightly
The price is $153
Sep 17 - Sep 18
Total with taxes and fees
Marriott Jacksonville Downtown

4. DoubleTree by Hilton Hotel Jacksonville Riverfront

DoubleTree by Hilton Hotel Jacksonville Riverfront
4.0 star property
Downtown Jacksonville
6.8 out of 10, (1,684 reviews)
$122 nightly
The price is $139
Sep 20 - Sep 21
Total with taxes and fees
DoubleTree by Hilton Hotel Jacksonville Riverfront

5. Sheraton Jacksonville Hotel

Sheraton Jacksonville Hotel
4.0 star property
Southside
9.2 out of 10, Wonderful, (1,001 reviews)
$124 nightly
The price is $140
Sep 12 - Sep 13
Total with taxes and fees
Sheraton Jacksonville Hotel

6. Delta Hotels by Marriott™ Jacksonville Deerwood

Delta Hotels by Marriott™ Jacksonville Deerwood
4.0 star property
Southside
8.4 out of 10, Very Good, (724 reviews)
$93 nightly
The price is $105
Sep 14 - Sep 15
Total with taxes and fees
Delta Hotels by Marriott™ Jacksonville Deerwood

7. DoubleTree by Hilton Hotel Jacksonville Airport

DoubleTree by Hilton Hotel Jacksonville Airport
4.0 star property
Northside
8.4 out of 10, Very Good, (1,727 reviews)
$98 nightly
The price is $111
Oct 4 - Oct 5
Total with taxes and fees
DoubleTree by Hilton Hotel Jacksonville Airport

8. Hilton Jacksonville at Mayo Clinic near Beaches

Hilton Jacksonville at Mayo Clinic near Beaches
4.5 star property
Jacksonville
9.4 out of 10, Exceptional, (352 reviews)
$156 nightly
The price is $177
Sep 20 - Sep 21
Total with taxes and fees
Hilton Jacksonville at Mayo Clinic near Beaches

9. Dune House Hotel & Spa

Dune House Hotel & Spa
4.5 star property
Atlantic Beach
8.8 out of 10, Excellent, (1,000 reviews)
  • cleanliness
    Beachfront elegance meets spa indulgence at this Atlantic Beach luxury hotel, where oceanfront views and full-service pampering await.
$253 nightly
The price is $287
Sep 17 - Sep 18
Total with taxes and fees
Dune House Hotel & Spa

10. Springhill Suites By Marriott Jacksonville Beach Oceanfront

Springhill Suites By Marriott Jacksonville Beach Oceanfront
4.0 star property
Oceanfront
9.0 out of 10, Wonderful, (789 reviews)
$173 nightly
The price is $197
Sep 20 - Sep 21
Total with taxes and fees
Springhill Suites By Marriott Jacksonville Beach Oceanfront
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find out more about San Marco

San Marcoand its attractions for luxury travelers

San Marco, a charming neighborhood in Jacksonville, Florida, offers a delightful blend of cultural experiences and upscale leisure activities that will appeal to luxury travelers seeking quality and pampering. Begin your journey at the iconic San Marco Square, where you can sip artisanal coffee at local cafes or indulge in gourmet dining at restaurants like The Capital Grille, known for its exquisite steaks and extensive wine list. For art enthusiasts, the nearby Museum of Contemporary Art Jacksonville showcases rotating exhibits from renowned artists, presenting a refined cultural experience just minutes from your hotel. Families can enjoy a day at the scenic San Marco Riverwalk, perfect for leisurely strolls while enjoying waterfront views, or take a private boat tour to explore the serene waterscape. And after a day of exploration, unwind at one of the luxury hotels in the area, where you’ll find spacious suites with modern amenities, rooftop pools with stunning views, and personalized service that caters to your every need, ensuring a stay that feels both indulgent and effortless. With a blend of vibrant local culture and sophisticated hospitality, San Marco is a perfect retreat for travelers.

Top San Marco Hotel Reviews

Frequently asked questions

Are you searching for a great accommodation for your luxury holiday in San Marco?
Expedia can help you get a flight to Jacksonville, FL (CRG-Jacksonville Executive at Craig) airport or Jacksonville International Airport (JAX) airport, and then you can select from a variety of places to stay that will deliver the luxury you seek. Amenities are an important consideration when you plan a trip, so we make it easy to get what you'd like to make your stay special. If you want a posh hotel with fine dining, a spa, or several swimming pools, Expedia can assist you in finding the best luxury hotel experience that San Marco offers. During your visit, you might want to enjoy the restaurants and bars which San Marco is known for.
What's there to see and do in San Marco?
Enjoy all that San Marco has to offer when you visit Theatre Jacksonville, St. Johns Town Center, and VyStar Ballpark. If you have extra time while you're in the area, you might want to stop by Daily's Place and Florida Theatre.

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