Name: Hotel Museo Spa Casa Santo Domingo
Price range: $296 total
Rating: 9.2

Barceló Guatemala City

7 Avenida 15-45, Zona 9 Guatemala City Guatemala

Fully refundableReserve now, pay when you stay

$100 nightly

$122 total

Jul 2 - Jul 3

Total with taxes and fees

Book a stay at this luxury hotel in Guatemala City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the breakfast and the pool in our ...

9.2/10 Wonderful! (3,326 reviews)

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Reviewed on Jun 1, 2026

Porta Hotel Antigua

8va Calle Poniente No1 Antigua Guatemala Sacatepequez

$179 nightly

$220 total

Jun 15 - Jun 16

Total with taxes and fees

Book a stay at this luxury hotel in Antigua Guatemala. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff and the clean ...

9.4/10 Exceptional! (1,001 reviews)

"La senal de internet en la habitacion puede mejorar."

Reviewed on May 25, 2026

Hotel Museo Spa Casa Santo Domingo

3a Calle Oriente No 28 A Antigua Guatemala Sacatepequez

$241 nightly

$296 total

Jul 1 - Jul 2

Total with taxes and fees

Book a stay at this luxury hotel in Antigua Guatemala. Enjoy free parking, a full-service spa, and 2 restaurants. Our guests praise the helpful staff and the ...

9.2/10 Wonderful! (1,067 reviews)

"Ok"

Reviewed on Jun 1, 2026

See all 1,254 properties in San Mateo Milpas Altas

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cabañas Casa Realeza

Cam. a Hobbitenango Antigua Guatemala Sacatepéquez

Stay at this cabin in Antigua Guatemala. Enjoy free WiFi, free parking, and daily housekeeping. Popular attractions Casa Santo Domingo Museum and Central Park ...

Suites Terraza Imperial

15 Ave. A 4-39 Zona 13 Guatemala City Guatemala

Stay at this aparthotel in Guatemala City. Enjoy free WiFi, free parking, and a fitness center. Popular attractions Paseo Cayala and El Obelisco are located ...

9/10 Wonderful! (347 reviews)

"My room it was very clean."

Reviewed on May 29, 2026

All Suite El Marques de Antigua

4 ave. South No. 30 Antigua Guatemala Sacatepequez

Stay at this aparthotel in Antigua Guatemala. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. Popular ...

9.4/10 Exceptional! (368 reviews)

"The condo did not have a/c. It wasn’t an issue for us because we had good weather, but that can be an issue in hotter months."

Reviewed on May 26, 2026

See all properties in San Mateo Milpas Altas

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Antigua Guatemala Cathedral

4.5/5(427 reviews)

After visiting Antigua Guatemala Cathedral, make a plan to see the other sights and activities in Antigua Guatemala. Discover the area's volcano viewpoints, or seek out its local tours.

Central Park

4.5/5(503 reviews)

Enjoy the volcano viewpoints and explore Central Park, a lovely green space in Antigua Guatemala. Discover the area's shops, or seek out its local tours.

Santa Catalina Arch

4.5/5(453 reviews)

Find out about the history of Antigua Guatemala when you spend time at Santa Catalina Arch. Discover the volcano viewpoints and shops in this family-friendly area.

Traditional vase and jar at market in Antigua, Guatemala.

Antigua Market

4.5/5(435 reviews)

During your trip to Antigua Guatemala, you can enjoy retail therapy at Antigua Market. Discover the volcano viewpoints in this romantic area, or enjoy its local tours.

La Merced Church

4.5/5(303 reviews)

After visiting La Merced Church, make a plan to see the other sights and activities in Antigua Guatemala. Discover the area's shops, or seek out its local tours.

Cerro de La Cruz

4.5/5(5 reviews)

You can find out about the history of Antigua Guatemala when you stop by Cerro de La Cruz. Discover the area's volcano viewpoints, or seek out its local tours.