Santa María Vacation Rentals

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Our top choices for Santa María vacation rentals

Apartamento ¡A 5 Minutos DEL Centro, LA Playa Y AL Eropuerto

Apartamento ¡A 5 Minutos DEL Centro, LA Playa Y AL Eropuerto
Cartagena de Indias
$129 nightly
The price is $147
May 9 - May 10
Apartamento ¡A 5 Minutos DEL Centro, LA Playa Y AL Eropuerto

Charming 2-bedroom apartment in lovely Cartagena de Indias with WiFi, AC

Charming 2-bedroom apartment in lovely Cartagena de Indias with WiFi, AC
Cartagena de Indias
$190 nightly
The price is $190
May 12 - May 13
Charming 2-bedroom apartment in lovely Cartagena de Indias with WiFi, AC

Apartamento premium en Baia Kristal

Apartamento premium en Baia Kristal
2.0 star property
Zona Norte
$109 nightly
The price is $109
May 10 - May 11
Apartamento premium en Baia Kristal

EcoHotel Hector

EcoHotel Hector
2.0 star property
Cartagena
10.0 out of 10, Exceptional, (4 reviews)
"Sin duda la mejor cabaña, la atenciòn excelente"
Colombia
Belkis
$47 nightly
The price is $47
May 9 - May 10
EcoHotel Hector

Bondo Hometel

Bondo Hometel
3.5 star property
Marbella
9.2 out of 10, Wonderful, (791 reviews)
"Very nice and pretty place to stay."
United States
Danna Ines Solarte
$71 nightly
The price is $71
Jun 3 - Jun 4
Bondo Hometel

LUXURY WATERFRONT BEDROOM with private bathroom and AC in Cielo Mar Cartagena

LUXURY WATERFRONT BEDROOM with private bathroom and AC in Cielo Mar Cartagena
La Boquilla
10.0 out of 10, Exceptional, (3 reviews)
"Excelente lugar para hospedarse, muy cerca del centro de convenciones de las americas y de playa azul, ademas una vista hermosa hacia el manglar, zona tranquila y segura. Excelente departamento, gran espacio, muy limpio y ordenado comodo, amenidades como alberca climatizada y gimnasio, un adecuado espacio para ir a descansar o por trabajo Anfitrión muy atento siempre"
Mexico
Maribel
$90 nightly
The price is $90
May 11 - May 12
LUXURY WATERFRONT BEDROOM with private bathroom and AC in Cielo Mar Cartagena

Cartagena Beach Resort

Cartagena Beach Resort
4.0 star property
Marbella
8.0 out of 10, Very Good, (26 reviews)
"The ocean view was really nice the room was equipped with all the kitchen appliances and plates cups pans and everything it’s really nice we loved the stay very clean and quiet"
United States
Jonathan
$82 nightly
The price is $82
May 12 - May 13
Cartagena Beach Resort

Baia Kristal Cartagena By HostPro

Baia Kristal Cartagena By HostPro
3.0 star property
Zona Norte
8.8 out of 10, Excellent, (12 reviews)
"The staff were great! The room was ok, hate that we had to buy our own toiletries. "
United States
Erica
$119 nightly
The price is $119
May 10 - May 11
Baia Kristal Cartagena By HostPro

MARINA DEL REY

MARINA DEL REY
4.0 star property
El Laguito
$96 nightly
The price is $96
May 9 - May 10
MARINA DEL REY

Soy Local Centro Historico

Soy Local Centro Historico
3.0 star property
Cartagena Walled City
8.6 out of 10, Excellent, (158 reviews)
"Good spot"
United States
Larry
$80 nightly
The price is $80
May 18 - May 19
Soy Local Centro Historico

Republic Deluxe – Modern Queen Room + Rooftop

Republic Deluxe – Modern Queen Room + Rooftop
Cartagena de Indias
$123 nightly
The price is $123
May 29 - May 30
Republic Deluxe – Modern Queen Room + Rooftop

SUNSET BEACH

SUNSET BEACH
2.5 star property
Cartagena
8.0 out of 10, Very Good, (14 reviews)
"Hotel and the beach were amazing. The staff was very helpful and nice. "
United States
Xiomara
$76 nightly
The price is $76
May 15 - May 16
SUNSET BEACH

De la Cruz Studio apartments

De la Cruz Studio apartments
3.0 star property
Cartagena Walled City
$84 nightly
The price is $84
May 12 - May 13
De la Cruz Studio apartments

Studio Apartment in Old City Cartagena Almirante

Studio Apartment in Old City Cartagena Almirante
Cartagena Walled City
$71 nightly
The price is $71
May 11 - May 12
Studio Apartment in Old City Cartagena Almirante

Incredible Apartment in Hotel Sonesta Cartagena Best Location in Town 6 People

Incredible Apartment in Hotel Sonesta Cartagena Best Location in Town 6 People
La Boquilla
8.6 out of 10, Excellent, (4 reviews)
"Good location. "
United States
Juan
$118 nightly
The price is $118
May 9 - May 10
Incredible Apartment in Hotel Sonesta Cartagena Best Location in Town 6 People

Boquilla del mar

Boquilla del mar
3.5 star property
Cartagena
$76 nightly
The price is $76
May 18 - May 19
Boquilla del mar

Beautiful and Spacious Apartment in Bocagrande

Beautiful and Spacious Apartment in Bocagrande
Bocagrande
9.2 out of 10, Wonderful, (12 reviews)
"The guards were one of the best parts about this trip I felt completely safe the entire time…I will definitely book again"
United States
OTR
$95 nightly
The price is $95
May 9 - May 10
Beautiful and Spacious Apartment in Bocagrande

Luxury Apartment with Ocean View

Luxury Apartment with Ocean View
Torices
10.0 out of 10, Exceptional, (5 reviews)
$107 nightly
The price is $107
May 17 - May 18
Luxury Apartment with Ocean View

Beachfront

Beachfront
3.5 star property
Bocagrande
$360 nightly
The price is $360
May 9 - May 10
Beachfront

Apartamentos en Edificio Portofino ICDI

Apartamentos en Edificio Portofino ICDI
3.0 star property
Bocagrande
7.2 out of 10, Good, (5 reviews)
"The security staff were amazing, so helpful at any time. A pleasant gentleman open my door every time I came back and went some things needed to be fixed, workers came within 5 minutes. "
United States
Amarilis
$86 nightly
The price is $86
May 18 - May 19
Apartamentos en Edificio Portofino ICDI
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santa María Hotel Reviews

Find out more about Santa María

Everything you need to know about Santa María vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Santa María vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santa María vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Santa María vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Santa María. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Santa María in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $69 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Santa María rentals

At Expedia, we put the best Santa María vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Santa María rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santa María vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santa María. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Frequently asked questions

Are there vacation rentals in Santa María?

Yes, we have vacation rentals near well known attractions in Santa María, or you can choose a secluded option if you're looking for relaxation.

What are some of the best vacation home rentals that Santa María has to offer?

Colonial loft in Cartagena old town: Located near Santa María, this vacation home rental is equipped with an outdoor pool, air-conditioning, and daily housekeeping to help you feel comfortable during your stay.

What’s there to see and do in Santa María?

While exploring the area, visit family-friendly sights like Caribbean Naval Museum, or get outside and enjoy nature at Marbella Beach. Las Americas International Convention Center and La Boquilla Beach are a couple of places you'll find in the larger area.

What’s a vacation rental in Santa María like?

Vacation rentals are privately owned properties you can book for short or long periods in Santa María. Vacation rentals offer amenities like kitchens and laundry facilities so you'll feel just like you're staying in your own home. If you're concerned about a clean environment, a vacation rental can offer a sense of security away from public hotel elevators and busy front desks while still allowing you a great travel experience. You'll also find more space in a vacation rental than in a hotel, which is another reason why a vacation rental is a great choice for family trips or small group gatherings.