Villas in Santee

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Check prices for these dates

Next weekend
Nov 13 - Nov 15
In two weeks
Nov 20 - Nov 22
In one month
Dec 4 - Dec 6
In two months
Jan 1 - Jan 3

Our top choices for Santee villas

A modern hotel with a blue and white facade, a covered entrance, and palm trees in front.

1. Tru By Hilton Santee

Tru By Hilton Santee
2.5 star property
Santee
9.2 out of 10, Wonderful, (1,011 reviews)
"Nice little hotel conveniently located."
United States
Armando
$103 nightly
The price is $114
Nov 29 - Nov 30
Total with taxes and fees
Tru By Hilton Santee
A Hampton Inn hotel at night with a well-lit facade and a parking lot in the foreground.

2. Hampton Inn Santee-I-95

Hampton Inn Santee-I-95
2.5 star property
Santee
9.6 out of 10, Exceptional, (1,000 reviews)
"Nice place to stay"
United States
sandra
$123 nightly
The price is $137
Nov 25 - Nov 26
Total with taxes and fees
Hampton Inn Santee-I-95
A hotel room with two beds, a grey armchair, a nightstand with a phone, and a cityscape picture on the wall.

3. Baymont by Wyndham Santee

Baymont by Wyndham Santee
2.5 star property
Santee
8.0 out of 10, Very good, (1,511 reviews)
"Good one night stay Staff was wonderful"
United States
Thomas
$80 nightly
The price is $89
Nov 8 - Nov 9
Total with taxes and fees
Baymont by Wyndham Santee
A multi-story hotel with a prominent sign, a covered entrance, and a parking lot.

4. Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee
3.0 star property
Santee
9.8 out of 10, Exceptional, (1,002 reviews)
"Convenient location close to the highway and restaurants. Large parking , excellent breakfast and comfortable room."
United States
Victor
$139 nightly
The price is $154
Nov 15 - Nov 16
Total with taxes and fees
Fairfield Inn & Suites by Marriott Santee
A hotel entrance with a sign reading "Best Western PLISS."

5. Best Western Plus Santee Inn

Best Western Plus Santee Inn
2.5 star property
Santee
8.8 out of 10, Excellent, (1,000 reviews)
"Nice location and very convenient parking, Breakfast was very good."
United States
Johnny
$118 nightly
The price is $131
Nov 15 - Nov 16
Total with taxes and fees
Best Western Plus Santee Inn
A Holiday Inn hotel with a covered entrance, multiple windows, and a landscaped front yard.

6. Holiday Inn Santee by IHG

Holiday Inn Santee by IHG
3.0 star property
Santee
8.2 out of 10, Very good, (1,000 reviews)
"Great staff and really clean room!"
United States
Traci
$115 nightly
The price is $128
Nov 15 - Nov 16
Total with taxes and fees
Holiday Inn Santee by IHG
A Comfort Inn hotel with a parking lot and a building facade.

7. Comfort Inn & Suites Santee

Comfort Inn & Suites Santee
2.5 star property
Santee
8.0 out of 10, Very good, (1,000 reviews)
"Great hotel"
United States
Alexis
$99 nightly
The price is $110
Nov 29 - Nov 30
Total with taxes and fees
Comfort Inn & Suites Santee
A motel with a brick facade, a covered entrance, and a satellite dish.

8. Travelodge by Wyndham Santee

Travelodge by Wyndham Santee
2.0 star property
Santee
7.2 out of 10, Good, (787 reviews)
"Extremely good value for money, room was clean, tidy and very well appointed. Will absolutely come here again."
United States
Robert
$64 nightly
The price is $71
Nov 16 - Nov 17
Total with taxes and fees
Travelodge by Wyndham Santee
A two-story building with a beige facade, large windows, and a central entrance.

9. Super 8 by Wyndham Santee/I-95

Super 8 by Wyndham Santee/I-95
2.0 star property
Santee
6.8 out of 10, (477 reviews)
"An older fecility but certainly well maintained. Loved Mr. Patel!"
United States
William
$64 nightly
The price is $71
Nov 12 - Nov 13
Total with taxes and fees
Super 8 by Wyndham Santee/I-95
A building with a covered entrance, a lawn, and a curved driveway.

10. Quality Inn & Suites Santee I-95

Quality Inn & Suites Santee I-95
2.5 star property
Santee
5.8 out of 10, (615 reviews)
"Clean room and nice staff"
United States
Louis
$59 nightly
The price is $65
Nov 29 - Nov 30
Total with taxes and fees
Quality Inn & Suites Santee I-95
A cabin with a porch, surrounded by trees and a body of water.

11. Red Roof Inn Santee

Red Roof Inn Santee
2.0 star property
Santee
6.6 out of 10, (668 reviews)
"Everything was adequate or good."
United States
Sharyn
$63 nightly
The price is $70
Nov 10 - Nov 11
Total with taxes and fees
Red Roof Inn Santee
A building with a red roof, a yellow door, and a brick facade.

12. Econo Lodge Santee

Econo Lodge Santee
2.0 star property
Santee
6.4 out of 10, (317 reviews)
"Pretty nice and clean with a comfortable bed at a great rate."
United States
Arthur
$63 nightly
The price is $70
Dec 7 - Dec 8
Total with taxes and fees
Econo Lodge Santee
A building with a large entrance, multiple windows, and potted plants in the foreground.

13. Ashburn Inn Manning I 95

Ashburn Inn Manning I 95
2.0 star property
Manning
$72 nightly
The price is $80
Nov 7 - Nov 8
Total with taxes and fees
Ashburn Inn Manning I 95
A tent with a view of a lake and boats, a wooden chair, and a potted plant.

14. Bells Marina & Resort

Bells Marina & Resort
2.5 star property
Eutawville
8.6 out of 10, Excellent, (103 reviews)
"Love it"
United States
Mark
$74 nightly
The price is $82
Nov 8 - Nov 9
Total with taxes and fees
Bells Marina & Resort
An outdoor patio area with seating arrangements, a table, and a wall with a patterned design.

15. Tru by Hilton Orangeburg

Tru by Hilton Orangeburg
2.5 star property
Orangeburg
9.2 out of 10, Wonderful, (1,003 reviews)
"Clean rooms, wonderful staff, excellent breakfast"
United States
Belinda
$110 nightly
The price is $122
Nov 22 - Nov 23
Total with taxes and fees
Tru by Hilton Orangeburg
A Fairfield Inn Marriott hotel with a modern design, multiple floors, and a parking lot with several cars.

16. Fairfield Inn by Marriott Orangeburg

Fairfield Inn by Marriott Orangeburg
3.0 star property
Orangeburg
8.4 out of 10, Very good, (850 reviews)
"Staff is great. However , the facility needs a refresh."
United States
Timothy
$97 nightly
The price is $108
Nov 15 - Nov 16
Total with taxes and fees
Fairfield Inn by Marriott Orangeburg
A two-story building with a sign reading "PachTree Inn".

17. Peach Tree Inn

Peach Tree Inn
2.5 star property
St. George
7.0 out of 10, Good, (270 reviews)
"Would not stay here again, bed was cheap and uncomfortable, carpet was dirty,TV wouldn't work and breakfast bar was a joke."
United States
BRENDA
$61 nightly
The price is $66
Nov 8 - Nov 9
Total with taxes and fees
Peach Tree Inn
A wooden pergola with a bench, a well-maintained lawn, and a parking area with buildings in the background.

18. SureStay Hotel by Best Western Manning

SureStay Hotel by Best Western Manning
2.5 star property
Manning
8.6 out of 10, Excellent, (1,003 reviews)
"Nice new mattress, comfy bed... decent bathroom with nice products... clean and very affordable"
United States
Tina
$82 nightly
The price is $91
Nov 22 - Nov 23
Total with taxes and fees
SureStay Hotel by Best Western Manning
A Hampton Inn & Suites hotel with a modern design, featuring a parking lot and a well-lit entrance.

19. Hampton Inn & Suites Orangeburg

Hampton Inn & Suites Orangeburg
2.5 star property
Orangeburg
9.4 out of 10, Exceptional, (862 reviews)
"Staffs are friendly, hotel is clean breakfast great .Stayed 3 nights."
United States
sonia
$127 nightly
The price is $141
Nov 25 - Nov 26
Total with taxes and fees
Hampton Inn & Suites Orangeburg
A building with a covered entrance, a parking lot, and a yellow vehicle.

20. Sunset Inn Manning I 95

Sunset Inn Manning I 95
2.0 star property
Summerton
5.2 out of 10, (65 reviews)
"Creepy, property is not well kept, and need a complete renovation."
United States
James
$58 nightly
The price is $63
Dec 7 - Dec 8
Total with taxes and fees
Sunset Inn Manning I 95
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Learn more about Santee

Nestled along Lake Marion, this charming town offers prime fishing and boating opportunities for outdoor enthusiasts. Visitors can tee off at Santee National Golf Club or explore nearby Santee State Park's hiking trails and campgrounds.

See all hotels in Santee
A tree with Spanish moss and autumn leaves in a body of water.

Top reviews in Santee

A multi-story hotel with a prominent sign, a covered entrance, and a parking lot.
Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee
Santee

10/10 Excellent

Choose this hotel for a pet-friendly stop-over on our drive to Florida and had a great experience. This staff was super-friendly and this nearly-brand-new property was immaculate. They have us a great 1st floor room with easy access to the walking and parking area. We took advantage of the patio to have dinner (take-out from a local restaurant) and breakfast with our dog. The breakfast was excellent, including hot omelets, eggs, and sausage, and the 6 am start (on a Sunday) allowed us to get...
United States
Douglas
Reviewed September 18, 2023
Fairfield Inn & Suites by Marriott Santee

Frequently Asked Questions

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Reserving a villa in Santee is as simple as entering your travel dates and choosing the option that suits your style. Looking for something upscale or budget friendly, or a property that also comes with WiFi and a hot tub? Use Expedia's search filters to narrow your results and find your perfect match.

How can I find cheap villas in Santee?

A fantastic way to get cheap villas in Santee is with Expedia's helpful filter tool. Narrow your search results by star rating, budget and amenities to secure unbeatable deals in just a couple of clicks.

What is there to do near my villa in Santee?

After you've unpacked your suitcases, venture out and discover the fun things Santee has on offer. Santee State Park is a popular attraction to add to your must-do list.

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