Find Resorts & Hotels with Spas in Southern Illinois, IL

Most hotels are fully refundable. Because flexibility matters.

Save 10% or more on over 100,000 hotels worldwide as a One Key member.

Search over 2.9 million properties and 550 airlines worldwide.

Pick from 45 Southern Illinois Resorts & Hotels with Spas and compare room rates, reviews, and availability. Most hotels are fully refundable.

Drury Inn Marion
3 out of 5
2706 W DeYoung St, Marion, IL
Fully refundableReserve now, pay when you stay
The price is $117 per night from Jun 18 to Jun 19
$117
per night
Jun 18 - Jun 19
9.4/10 Exceptional! (1,000 reviews)
Lovely Stay
"Beds were comfortable, the hotel was very clean, breakfast was good. Definitely will be our choice stay when we visit our family again."

Reviewed on Jun 4, 2023

Drury Inn Marion
Drury Inn & Suites St. Louis Fairview Heights
3 out of 5
12 Ludwig Dr, Fairview Heights, IL
Fully refundableReserve now, pay when you stay
The price is $103 per night from Jun 18 to Jun 19
$103
per night
Jun 18 - Jun 19
9/10 Wonderful! (1,001 reviews)
"Nice"

Reviewed on May 30, 2023

Drury Inn & Suites St. Louis Fairview Heights
Comfort Suites Mount Vernon
2.5 out of 5
404 South 44th Street, Mount Vernon, IL
Fully refundableReserve now, pay when you stay
The price is $130 per night from Jul 5 to Jul 6
$130
per night
Jul 5 - Jul 6
8.8/10 Excellent! (1,001 reviews)
"The staff was amazing and very accommodating. We were very nicely surprised to see a hot tub in our room which made my wife very happy. Also I noticed that there are chargers here for electric vehicles, however, we had actually just charged up a half of mile down the road. So the only thing that ..."

Reviewed on Jun 8, 2023

Comfort Suites Mount Vernon

Save an average of 15% on thousands of hotels when you're signed in

Country Inn & Suites by Radisson, Effingham, IL
2.5 out of 5
1200 N Raney, Effingham, IL
Fully refundable
The price is $117 per night from Jun 18 to Jun 19
$117
per night
Jun 18 - Jun 19
8.8/10 Excellent! (1,000 reviews)
"Very nice staff"

Reviewed on Jun 8, 2023

Country Inn & Suites by Radisson, Effingham, IL
Holiday Inn Express Metropolis, an IHG Hotel
2.5 out of 5
2179 East 5th Street, Metropolis, IL
Fully refundableReserve now, pay when you stay
The price is $103 per night from Jun 26 to Jun 27
$103
per night
Jun 26 - Jun 27
8/10 Very Good! (833 reviews)
"Convenient location off highway, smooth check in and out, room was clean. there is a shelf right outside the bathroom door which was very convenient to put your cosmetics or keys, cups, as such. Breakfast was nothing special. overall we were satisfied."

Reviewed on Jun 7, 2023

Holiday Inn Express Metropolis, an IHG Hotel
Quality Inn O'Fallon I-64
2.5 out of 5
1409 W US 50, O'Fallon, IL
Fully refundableReserve now, pay when you stay
The price is $76 per night from Jun 19 to Jun 20
$76
per night
Jun 19 - Jun 20
7.6/10 Good! (649 reviews)
"Overall a very pleasant stay and experience. Staff was nice to handle any issues arisen."

Reviewed on Jun 1, 2023

Quality Inn O'Fallon I-64
Americas Best Value Inn Mount Vernon
2.5 out of 5
222 South 44th Street, Mount Vernon, IL
Fully refundableReserve now, pay when you stay
The price is $89 per night from Jun 11 to Jun 12
$89
per night
Jun 11 - Jun 12
6.8/10 (275 reviews)
Good nights sleep
"The stay was nice."

Reviewed on Feb 1, 2023

Americas Best Value Inn Mount Vernon
Baymont by Wyndham Metropolis
2.5 out of 5
203 E Front St, Metropolis, IL
Fully refundableReserve now, pay when you stay
The price is $49 per night from Jun 19 to Jun 20
$49
per night
Jun 19 - Jun 20
6.4/10 (999 reviews)
"Just an overnight stay to break up a longer trip. Very good location. Easy to find."

Reviewed on Apr 24, 2023

Baymont by Wyndham Metropolis
Days Inn by Wyndham Pontoon Beach
2 out of 5
5105 Highway 111, Granite City, IL
Fully refundableReserve now, pay when you stay
The price is $69 per night from Jul 2 to Jul 3
$69
per night
Jul 2 - Jul 3
6/10 (437 reviews)
"It was good enough for a cheap hotel. It was kind of a throw back because it looked like it was still trapped in the 80s. The staff is super nice but yea, that place needs a face lift and they need to work on keeping it clean."

Reviewed on Apr 25, 2023

Days Inn by Wyndham Pontoon Beach
Days Inn & Suites by Wyndham Caseyville
2.5 out of 5
2423 Old Country Inn Drive, Caseyville, IL
Fully refundableReserve now, pay when you stay
The price is $63 per night from Jul 2 to Jul 3
$63
per night
Jul 2 - Jul 3
3.6/10 (92 reviews)
"After paying for our stay through Expedia we got here and they charged more money and then when we got to our room there was no trash can the floors while newer looking didn’t even go all the way to the walls and the smell of 420 was enough to choke a person. When we got up the next morning our truck ..."

Reviewed on Jun 6, 2023

Days Inn & Suites by Wyndham Caseyville
Don't see what you're looking for?
See all available properties in Southern Illinois
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Southern Illinois Resorts & Hotels with Spas information

 

Resorts & Hotels with Spas in Southern Illinois

45

Highest price
$130
Cheapest price
$49
Number of guest reviews
7,287
Total number of hotels in Southern Illinois
796

 

Recent reviews of Southern Illinois hotels
Expedia verified reviews