Murphysboro Vacation Rentals

  • Bundle & Save

    Get more, spend less whenever you see Bundle & Save deals

  • OneKeyCash

    Earn OneKeyCash on all your eligible bookings

  • Upfront pricing

    We are not like the others - we include taxes and fees

Check prices for these dates

In two weeks
May 22 - May 24
In two months
Jul 3 - Jul 5
In three months
Jul 31 - Aug 2
In four months
Aug 28 - Aug 30

Our top choices for Murphysboro vacation rentals

Property grounds

Pet-Friendly Lakeside Gem 4 Mi to Dtwn Murphysboro

Pet-Friendly Lakeside Gem 4 Mi to Dtwn Murphysboro
Murphysboro
8.0 out of 10, Very Good, (3 reviews)
"Perfect but beware if you are a sensitive sleeper as the mattress on the queen bed is saggy and in need of replacing. Probably fine for 1 person but 2 people easily roll into the middle making for a not-so-good night's sleep."
United States
Pamela S.
$221 nightly
The price is $241
May 7 - May 8
Total with taxes and fees
Pet-Friendly Lakeside Gem 4 Mi to Dtwn Murphysboro
House (1 Bedroom) | Front of property

Pet Friendly! Countryside Couples Stay in Illinois

Pet Friendly! Countryside Couples Stay in Illinois
2.5 star property
Murphysboro
$217 nightly
The price is $238
May 7 - May 8
Total with taxes and fees
Pet Friendly! Countryside Couples Stay in Illinois
Smart TV

Charming 3-bedroom house in tranquil Oraville minutes from Kinkaid Lake.

Charming 3-bedroom house in tranquil Oraville minutes from Kinkaid Lake.
Oraville
10.0 out of 10, Exceptional, (4 reviews)
"Very nice place, will definitely be back."
United States
Greg W.
$256 nightly
The price is $271
May 10 - May 11
Total with taxes and fees
Charming 3-bedroom house in tranquil Oraville minutes from Kinkaid Lake.
Exterior

Pet Friendly! Couples Retreat in Southern Illinois

Pet Friendly! Couples Retreat in Southern Illinois
Murphysboro
8.0 out of 10, Very Good, (1 review)
"Easy check in and was very clean and close to everything. "
United States
Stephen
$214 nightly
The price is $234
May 7 - May 8
Total with taxes and fees
Pet Friendly! Couples Retreat in Southern Illinois
Smart TV

The Lab! Come stay in our brand new space.

The Lab! Come stay in our brand new space.
Murphysboro
9.6 out of 10, Exceptional, (25 reviews)
"Clean, great accommodations. Just watch out if you have little ones the stairs are a bit scary. "
United States
Kaitlin B.
$193 nightly
The price is $204
May 7 - May 8
Total with taxes and fees
The Lab! Come stay in our brand new space.
Microwave, oven, stovetop

Fishing Cabin next to Kinkaid Lake

Fishing Cabin next to Kinkaid Lake
Murphysboro
10.0 out of 10, Exceptional, (1 review)
"Cabin was fine. Beds were good, kitchen was clean. Rooms were clean also. The hosts provided excellent extras that made a big difference. Toilets worked just fine. Since we were both in our 70s we found it tough to sit as they were quite low and seemed small. Grill was ok. Could use a burner cover on one of the burners but that did not affect our use.Overall it was a very good cabin. A fishing cabin!Picnic table outside was rotted and one section gave way when my partner rested his elbows on it....
United States
thomas s.
$240 nightly
The price is $254
May 7 - May 8
Total with taxes and fees
Fishing Cabin next to Kinkaid Lake
Exterior

Pet Friendly! Countryside Couples Stay in Illinois

Pet Friendly! Countryside Couples Stay in Illinois
Murphysboro
8.0 out of 10, Very Good, (1 review)
"We really enjoyed our stay overall. The location was excellent—quiet, peaceful, and set far enough away from town to avoid traffic, but still close enough to get anywhere quickly. The outdoor space was a big plus, especially for our dogs, who had plenty of room to roam. The beds were also very comfortable, which made for a great night’s sleep. The only downside was the cleanliness. The property was noticeably dusty, and the inside of the refrigerator could have been cleaned more thoroughly. With...
United States
Jim P.
$221 nightly
The price is $241
May 7 - May 8
Total with taxes and fees
Pet Friendly! Countryside Couples Stay in Illinois
Pool

Experience Glamping in style. private Hot tub spa! Private lake -Pet Friendly

Experience Glamping in style. private Hot tub spa! Private lake -Pet Friendly
De Soto
9.8 out of 10, Exceptional, (21 reviews)
"Had a very pleasant stay and host were very accommodating!"
United States
Nicole G.
$153 nightly
The price is $169
May 7 - May 8
Total with taxes and fees
Experience Glamping in style. private Hot tub spa! Private lake -Pet Friendly
Outdoor pool

Experience Glamping in style. Private Lake - Pet Friendly!

Experience Glamping in style. Private Lake - Pet Friendly!
De Soto
10.0 out of 10, Exceptional, (45 reviews)
"Awesome spot and very helpful host. "
United States
heath w.
$143 nightly
The price is $158
May 7 - May 8
Total with taxes and fees
Experience Glamping in style. Private Lake - Pet Friendly!
Outdoor pool

Experience Glamping in style. Private Hot tub spa! Private lake -Pet Friendly

Experience Glamping in style. Private Hot tub spa! Private lake -Pet Friendly
De Soto
9.6 out of 10, Exceptional, (37 reviews)
"Great glamping"
United States
Robert H.
$164 nightly
The price is $182
May 7 - May 8
Total with taxes and fees
Experience Glamping in style. Private Hot tub spa! Private lake -Pet Friendly
Exterior

Rest, Relax and Renew. Our log cabin experience awaits your arrival.

Rest, Relax and Renew. Our log cabin experience awaits your arrival.
Anna
10.0 out of 10, Exceptional, (409 reviews)
"Great location. Cozy cabin. Would stay there again. "
United States
jeffrey s
$191 nightly
The price is $202
May 7 - May 8
Total with taxes and fees
Rest, Relax and Renew. Our log cabin experience awaits your arrival.
Exterior

Maple Ridge Cabin at Panther's Rest

Maple Ridge Cabin at Panther's Rest
Makanda
9.6 out of 10, Exceptional, (26 reviews)
"We loved our stay and will definitely be back! "
United States
Ashley M.
$135 nightly
The price is $143
May 7 - May 8
Total with taxes and fees
Maple Ridge Cabin at Panther's Rest
Smart TV, books

Cozy Lake of Egypt Cabin & Pond

Cozy Lake of Egypt Cabin & Pond
Marion
10.0 out of 10, Exceptional, (136 reviews)
"Host was excellent and the place was well stocked "
United States
Tom C.
$191 nightly
The price is $211
May 11 - May 12
Total with taxes and fees
Cozy Lake of Egypt Cabin & Pond
Interior

Romantic Cabin w/ Hot Tub Near Carbondale

Romantic Cabin w/ Hot Tub Near Carbondale
Carbondale
10.0 out of 10, Exceptional, (108 reviews)
"The stay was very comfortable and clean. The host was amazing, kept in good contact! The cabin was very welcoming! "
United States
Andrea T.
$226 nightly
The price is $249
May 11 - May 12
Total with taxes and fees
Romantic Cabin w/ Hot Tub Near Carbondale
Terrace/patio

Contemporary Glamping with Native American Appeal

Contemporary Glamping with Native American Appeal
Anna
9.8 out of 10, Exceptional, (158 reviews)
"They hosts are very welcoming and attentive. The home was clean and prepped for our visit. "
United States
Lynette G.
$319 nightly
The price is $321
May 10 - May 11
Total with taxes and fees
Contemporary Glamping with Native American Appeal
Dining

Comfy Clean & Cute

Comfy Clean & Cute
Marion
9.0 out of 10, Wonderful, (32 reviews)
"Convenient location"
United States
Johnathan R.
$185 nightly
The price is $222
May 7 - May 8
Total with taxes and fees
Comfy Clean & Cute
Interior

Shawnee Wine Trail Farm Stay

Shawnee Wine Trail Farm Stay
Makanda
10.0 out of 10, Exceptional, (14 reviews)
"We loved our stay and all the wonderful animals we got to see."
United States
Jasmine B.
$119 nightly
The price is $126
May 12 - May 13
Total with taxes and fees
Shawnee Wine Trail Farm Stay
Interior

Cozy and Updated Farmhouse with King Suite

Cozy and Updated Farmhouse with King Suite
Anna
9.8 out of 10, Exceptional, (10 reviews)
"Nice little house that was perfect for our family of five plus our dog. We would stay here again if we found ourselves out this way again."
United States
Kyle
$149 nightly
The price is $158
May 7 - May 8
Total with taxes and fees
Cozy and Updated Farmhouse with King Suite
Property grounds

Charming 3 bedroom retreat

Charming 3 bedroom retreat
Herrin
10.0 out of 10, Exceptional, (1 review)
"We stayed here while visiting family in the area. Clean and well maintained property to relax in after a long day of fun with the family. The property manager is amazing and very helpful. I definitely recommend staying here and we will be back."
United States
Ronald H.
$265 nightly
The price is $294
May 7 - May 8
Total with taxes and fees
Charming 3 bedroom retreat
Property grounds

The Brunette Treehouse

The Brunette Treehouse
Marion
10.0 out of 10, Exceptional, (9 reviews)
"Lovely place to stay, quiet, peaceful. Kid and pet friendly."
United States
Rhiannon H.
$243 nightly
The price is $263
May 11 - May 12
Total with taxes and fees
The Brunette Treehouse
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Murphysboro Hotel Reviews

Quality Inn & Suites Marion

Quality Inn & Suites Marion

8/10 Good
"Breakfast was below average."
roger 1-night trip
Posted 6 hours ago
Quality Inn & Suites Marion

Find out more about Murphysboro

Everything you need to know about Murphysboro vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Murphysboro vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Murphysboro vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Murphysboro vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Murphysboro. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Murphysboro in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $151 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Murphysboro rentals

At Expedia, we put the best Murphysboro vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Murphysboro rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Murphysboro vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Murphysboro. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Explore a world of travel with Expedia

Frequently asked questions

Are there vacation rentals in Murphysboro?

Yes, there are vacation rentals near the most popular points of interest in Murphysboro, or you can select a secluded option if you'd like a relaxing place to stay. Murphysboro is known for its restaurants and golf courses. Make sure you have time to check out the parks and museums during your trip.

What are some of the best vacation rentals in Murphysboro?

On the Lake & Wine Trail & a Perfect Getaway for 16+ With an ADA Suite!: Visitors give good reviews to this Murphysboro vacation home rental, which is located on a lake and has a fireplace, a balcony, and a barbecue grill to put you at ease in your new surroundings. It has 7 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Kick off your shoes and enjoy yourself with a garden and a selection of games. Another good choice for your trip to Murphysboro is 5 Star Cabin LUXURY AMMENITIES W/POOL HTUB close to WINE TRAIL, HIKING, FISHING.

How many vacation rentals are there in Murphysboro?

Choose from 15 Expedia vacation rentals in Murphysboro for a memorable vacation.

What’s there to see and do in Murphysboro?

Shawnee National Forest and Parkview Park are a couple of scenic spots to enjoy the outdoors, whereas General John A. Logan Museum is one of the cultural attractions. Other places in town to visit include Hickory Ridge Public Golf Center and Kinkaid Village Marina.

What’s a vacation rental in Murphysboro like?

A vacation rental is a private property you can book for short or long periods in Murphysboro. Vacation rentals offer amenities such as WiFi and washers and dryers so you'll feel just like you're at home. If you're concerned about a clean environment, vacation rentals can offer a sense of safety away from shared hotel elevators and busy front desks while still allowing you the enjoyment of travel. You'll also get more space in a vacation rental than in a hotel, which makes a vacation rental a popular choice for family trips.