Photo by Southernmost Illinois Tourism Bureau
Find Southern Illinois motels
- Bundle & SaveGet more, spend less whenever you see Bundle & Save deals
- OneKeyCashEarn OneKeyCash on all your eligible bookings
- Upfront pricingWe are not like the others - we include taxes and fees
Check prices for these dates
Next weekend
In two weeks
In one month
In two months
Motels in Southern Illinois

Super 8 by Wyndham Greenville
Greenville
8.0 out of 10, Very Good, (752)
$60 nightly
The price is $66
Dec 1 - Dec 2
Total with taxes and fees

Budget Host Inn Greenup
Greenup
7.8 out of 10, Good, (449)
$70 nightly
The price is $78
Nov 23 - Nov 24
Total with taxes and fees

The Shelby Inn
Shelbyville
8.8 out of 10, Excellent, (128)
$127 nightly
The price is $138
Nov 30 - Dec 1
Total with taxes and fees

Powhatan Motel
Pocahontas
8.6 out of 10, Excellent, (191)
$97 nightly
The price is $103
Nov 23 - Nov 24
Total with taxes and fees

Rodeway Inn Effingham North
Effingham
7.6 out of 10, Good, (1002)
$54 nightly
The price is $60
Nov 23 - Nov 24
Total with taxes and fees

Americas Best Value Inn West Frankfort
West Frankfort
7.6 out of 10, Good, (472)
$68 nightly
The price is $75
Nov 23 - Nov 24
Total with taxes and fees

Motel 6 Mount Vernon, IL
Mount Vernon
7.2 out of 10, Good, (921)
$61 nightly
The price is $70
Nov 30 - Dec 1
Total with taxes and fees

Americas Best Value Inn Vandalia
Vandalia
7.8 out of 10, Good, (185)
$50 nightly
The price is $55
Nov 30 - Dec 1
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Southern Illinois Hotel Reviews

Drury Inn & Suites St. Louis O'Fallon, IL
10/10 Excellent
Find out more about Southern Illinois
Southern Illinois Motels information
Number of reviews | |
|---|---|
Accommodation | Motels |
Lowest Price | |
Highest Price |
Frequently asked questions
Explore a world of travel with Expedia
- Mount Vernon Hotels
- Hotels near Jefferson County Fairgrounds
- Hotels near Mount Vernon Outland
- Cabin Rentals in Mount Vernon
- Motels in Mount Vernon
- Apartments in Mount Vernon
- RV Parks in Mount Vernon
- Vacation Homes in Opdyke
- Pet-friendly Hotels in Mount Vernon
- Cheap Hotels in Mount Vernon
- Hotels with Bars in Mount Vernon
- Hotels with Restaurants in Mount Vernon
- Hotels with Hot Tubs in Mount Vernon
- 5 Star Hotels in Mount Vernon
- Hotels with an Indoor Pool in Mount Vernon
- Hotels with an Outdoor Pool in Mount Vernon
- Luxury Hotels in Mount Vernon
- Hotels with Free Breakfast in Mount Vernon
- 4 Star Hotels in Mount Vernon
- Resorts & Hotels with Spas in Mount Vernon
- Best Western Hotels in Mount Vernon
- Hotels with Connecting Rooms in Mount Vernon
- Non-Smoking Hotels in Mount Vernon
- Hotel Wedding Venues Hotels in Mount Vernon
- Hotels with Room Service in Mount Vernon
- Marriott Hotels & Resorts in Mount Vernon
- Hotels with Laundry Facilities in Mount Vernon
- Hotels with Free Parking in Mount Vernon
- Family Hotels in Mount Vernon
- Hotels with Balconies in Mount Vernon
- Hotels & Resorts for Couples in Mount Vernon
- Golf Hotels in Mount Vernon
- Hotels with a Gym in Mount Vernon
- Hotels with Suites in Mount Vernon
- Hotels with Air Conditioning in Mount Vernon
- Gay friendly Hotels in Mount Vernon
- Hotels with a Pool in Mount Vernon
- 3 Star Hotels in Mount Vernon
- Wyndham Hotels in Mount Vernon
- Business Hotels in Mount Vernon
- Opdyke Hotels
- 5 Star Hotels in Opdyke
- 4 Star Hotels in Opdyke
- Hotels near Veterans Memorial Park
- Hotels near King City Square Shopping Center
- Bonnie Hotels
- Cabin Rentals in Belle Rive
- Flights from Mount Vernon Outland
- Flights from Chicago (ORD) to Mount Vernon (MVN)
- Flights from Nashville (BNA) to Mount Vernon (MVN)
- Flights from Houston (HOU) to Mount Vernon (MVN)
- Flights from Denver (DEN) to Mount Vernon (MVN)
- Flights from Orlando (MCO) to Mount Vernon (MVN)
- Flights from Detroit (DTW) to Mount Vernon (MVN)
- Flights from Charlotte (CLT) to Mount Vernon (MVN)
- Flights from San Diego (SAN) to Mount Vernon (MVN)
- Flights from Baltimore (BWI) to Mount Vernon (MVN)
- Flights from Seattle (SEA) to Mount Vernon (MVN)
- Flights from Minneapolis (MSP) to Mount Vernon (MVN)
- Flights from Raleigh (RDU) to Mount Vernon (MVN)
- Flights from Pensacola (PNS) to Mount Vernon (MVN)
- Flights from Vancouver (YVR) to Mount Vernon (MVN)
- Flights from Atlanta (ATL) to Mount Vernon (MVN)
- Flights from Fort Myers (RSW) to Mount Vernon (MVN)
- Flights from Buffalo (BUF) to Mount Vernon (MVN)
- Flights from Grand Rapids (GRR) to Mount Vernon (MVN)
- Flights from Manchester (MAN) to Mount Vernon (MVN)
- Flights from Los Angeles (LAX) to Mount Vernon (MVN)
- Flights from Tampa (TPA) to Mount Vernon (MVN)
- Flights from Charlottesville (CHO) to Mount Vernon (MVN)
- Hopscotch Air Chicago (MDW) to Mount Vernon (MVN) flights
- Flights from Cape Girardeau (CGI) to Mount Vernon (MVN)
- Flights to Mount Vernon
- Flights from Mount Vernon
- Flights from Nashville to Mount Vernon
- Flights from Los Angeles to Mount Vernon
- Flights from Hilo to Mount Vernon
- Flights from Charlottesville to Mount Vernon
- Flights from Atlanta to Mount Vernon
- Flights from Buffalo to Mount Vernon
- Flights from Amsterdam to Mount Vernon
- Flights from West Palm Beach to Mount Vernon
- Flights from Palm Beach to Mount Vernon
- Flights from Opdyke
- Car rental Mount Vernon Airport (MVN)
- Car rentals near Mount Vernon
- Hertz Rental Cars in Mount Vernon
- Avis Rental Cars in Mount Vernon
- Enterprise Rental Cars in Mount Vernon
- Budget Rental Cars in Mount Vernon
- National Car Rental Rental Cars in Mount Vernon
- Alamo Rent A Car Rental Cars in Mount Vernon
- Car rentals near Opdyke

















































































