Title: The Best Southern Indiana Spa Resorts from $93 - Resorts & Spa in Southern Indiana | Expedia.com [Southern Indiana Travel Guide](https://expedia.com/Southern-Indiana.dx6059635)[Hotels in Southern Indiana](https://expedia.com/Southern-Indiana-Hotels.d6059635.Travel-Guide-Hotels)[Vacation Rentals in Southern Indiana](https://expedia.com/Southern-Indiana-Vacation-Rentals.d6059635.Travel-Guide-VacationRentals)[Flights to Southern Indiana](https://expedia.com/Cheap-Flights-To-Southern-Indiana.d6059635.Travel-Guide-Flights)[Car Rentals in Southern Indiana](https://expedia.com/Car-Rentals-In-Southern-Indiana.d6059635.Car-Rental-Guide)[Southern Indiana Vacation Packages](https://expedia.com/Southern-Indiana.d6059635.Destination-Travel-Guides) ![](https://images.trvl-media.com/place/6062661/de2e6e20-7fec-4f19-8f1c-b6f175615380.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6062661/de2e6e20-7fec-4f19-8f1c-b6f175615380.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Southern Indiana Resorts & Hotels with Spas Tonight [Apr 4 - Apr 5](https://www.expedia.com/Hotel-Search?regionId=6059635&startDate=2026-04-04&endDate=2026-04-05&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Apr 5 - Apr 6](https://www.expedia.com/Hotel-Search?regionId=6059635&startDate=2026-04-05&endDate=2026-04-06&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Apr 10 - Apr 12](https://www.expedia.com/Hotel-Search?regionId=6059635&startDate=2026-04-10&endDate=2026-04-12&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Apr 17 - Apr 19](https://www.expedia.com/Hotel-Search?regionId=6059635&startDate=2026-04-17&endDate=2026-04-19&adults=2&amenities=SPA_ON_SITE&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Southern Indiana hotels with a spa ![Deep-tissue massages, Swedish massages, massages](https://images.trvl-media.com/lodging/2000000/1160000/1152900/1152807/14efb4b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/2000000/1160000/1152900/1152807/04047b8f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Golf](https://images.trvl-media.com/lodging/2000000/1160000/1152900/1152807/7f00b921.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Seasonal outdoor pool, open 9:00 AM to 9:00 PM, cabanas (surcharge)](https://images.trvl-media.com/lodging/2000000/1160000/1152900/1152807/162eb275.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Belterra Casino Resort [](https://www.expedia.com/Madison-Hotels-Belterra-Casino-Resort.h1152807.Hotel-Information) Florence 8.6/10 Excellent (1,002 reviews) - Experience soothing river views and rejuvenating spa treatments at this hotel with indoor and outdoor pools. $155 nightly $173 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Madison-Hotels-Belterra-Casino-Resort.h1152807.Hotel-Information) ![3 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/800000/795900/795844/54f0e03a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/800000/795900/795844/80fbdedc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/1000000/800000/795900/795844/506c167d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Casino](https://images.trvl-media.com/lodging/1000000/800000/795900/795844/a36c57b3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Caesars Southern Indiana - A Caesars Rewards Destination [](https://www.expedia.com/Elizabeth-Hotels-Caesars-Southern-Indiana.h795844.Hotel-Information) Elizabeth 8.2/10 Very Good (1,001 reviews) - Refresh your spirit at this riverfront hotel with daily spa treatments and couples rooms, where aromatherapy and Ayurvedic therapies await. $83 nightly $93 total May 4 - May 5 Total with taxes and fees [](https://www.expedia.com/Elizabeth-Hotels-Caesars-Southern-Indiana.h795844.Hotel-Information) ![4 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/aa5bcd07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![4 restaurants, breakfast, lunch, dinner served; American cuisine](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/0261f02d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/63654a82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![In-room safe, desk, laptop workspace, iron/ironing board](https://images.trvl-media.com/lodging/1000000/200000/191500/191434/9d86b349.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Galt House Hotel Trademark Collection by Wyndham [](https://www.expedia.com/Louisville-Hotels-Galt-House-Hotel-Trademark-Collection-By-Wyndham.h191434.Hotel-Information) Downtown Louisville 9.0/10 Wonderful (4,139 reviews) - Riverside sanctuary offers rejuvenating spa treatments, panoramic fitness views, and river-facing balconies for a relaxing urban retreat. $159 nightly $187 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Louisville-Hotels-Galt-House-Hotel-Trademark-Collection-By-Wyndham.h191434.Hotel-Information) ![Room (Asleep in the Cyclone) | Premium bedding, down comforters, minibar, in-room safe](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/fdd94051.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fountain](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/864ff441.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room (Asleep in the Cyclone) | Premium bedding, down comforters, minibar, in-room safe](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/aaadeb96.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/2000000/1420000/1413400/1413350/22b7d23e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 21c Museum Hotel Louisville [](https://www.expedia.com/Louisville-Hotels-21c-Museum-Hotel-Louisville.h1413350.Hotel-Information) Downtown Louisville 9.4/10 Exceptional (1,001 reviews) - Experience a rejuvenating spa escape at this luxury boutique hotel with massage rooms and 24-hour fitness center in downtown Louisville. $183 nightly $216 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Louisville-Hotels-21c-Museum-Hotel-Louisville.h1413350.Hotel-Information) ![Sauna, body treatments, aromatherapy, hot stone massages](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/4c7c479b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool, open 6:00 AM to 10:00 PM, cabanas (surcharge)](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/e2fb9d56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bars/lounges, cocktail bar, lobby lounge](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/547de83e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior detail](https://images.trvl-media.com/lodging/22000000/21110000/21106200/21106192/9798709f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Omni Louisville Hotel [](https://www.expedia.com/Louisville-Hotels-Omni-Louisville-Hotel.h21106192.Hotel-Information) Downtown Louisville 9.2/10 Wonderful (1,816 reviews) - Immerse in spa bliss at this Louisville hotel where Mokara Spa offers therapeutic treatments and rooftop relaxation awaits. $183 nightly $216 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Louisville-Hotels-Omni-Louisville-Hotel.h21106192.Hotel-Information) ![Exterior detail](https://images.trvl-media.com/lodging/107000000/106920000/106915400/106915308/95d9177a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/107000000/106920000/106915400/106915308/94b6bd82.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/107000000/106920000/106915400/106915308/787112cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/107000000/106920000/106915400/106915308/62c45f98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Central Park Bed & Breakfast [](https://www.expedia.com/Louisville-Hotels-Central-Park-Bed-Breakfast.h106915308.Hotel-Information) Old Louisville 9.2/10 Wonderful (72 reviews) - Rejuvenate at this Victorian bed & breakfast featuring deep soaking tubs, fireplaces in rooms, and personalized spa services. $134 nightly $156 total Apr 7 - Apr 8 Total with taxes and fees [](https://www.expedia.com/Louisville-Hotels-Central-Park-Bed-Breakfast.h106915308.Hotel-Information) ![Bar (on property)](https://images.trvl-media.com/lodging/12000000/11690000/11688300/11688222/40c412dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature Apartment, 1 King Bed with Sofa bed, Pets Allowed, Garden View | Terrace/patio](https://images.trvl-media.com/lodging/12000000/11690000/11688300/11688222/46f16aa2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Apartment, Multiple Beds, Pets Allowed, Garden View | Living area | 42-inch flat-screen TV with digital channels, TV, Netflix](https://images.trvl-media.com/lodging/12000000/11690000/11688300/11688222/3fd39b2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/12000000/11690000/11688300/11688222/82066f84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pillow and Paddock B&B [](https://www.expedia.com/Louisville-Hotels-Pillow-And-Paddock-BB.h11688222.Hotel-Information) La Grange 10/10 Exceptional (52 reviews) - Relax in a cozy bed and breakfast retreat with a steamy hot tub, rejuvenating spa services, and a peaceful garden sanctuary. $332 nightly $366 total Apr 9 - Apr 10 Total with taxes and fees [](https://www.expedia.com/Louisville-Hotels-Pillow-And-Paddock-BB.h11688222.Hotel-Information) ![Lobby](https://images.trvl-media.com/lodging/1000000/50000/49600/49545/a62748ff.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Indoor pool](https://images.trvl-media.com/lodging/1000000/50000/49600/49545/1ea5b0fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Free continental breakfast](https://images.trvl-media.com/lodging/1000000/50000/49600/49545/d25d1009.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Iron/ironing board, free WiFi, bed sheets, alarm clocks](https://images.trvl-media.com/lodging/1000000/50000/49600/49545/914ff829.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Quality Inn Seymour I-65 [](https://www.expedia.com/Columbus-Hotels-Quality-Inn-Seymour-I-65.h49545.Hotel-Information) Seymour 7.0/10 Good (576 reviews) - Revitalize your body and spirit in this tranquil hotel featuring a full-service daily spa, indoor pool, and 24-hour fitness center. $85 nightly $95 total May 4 - May 5 Total with taxes and fees [](https://www.expedia.com/Columbus-Hotels-Quality-Inn-Seymour-I-65.h49545.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-04-18&endDate=2026-04-08®ionId=6059635&adults=2&amenities=SPA_ON_SITE&sort=RECOMMENDED&openPlayBack=true) ## Choose what matters most at spa hotels in Southern Indiana Pool Breakfast included Hot tub 4 stars 5 stars ## Find out more about Southern Indiana ### Top Southern Indiana attractions for a relaxing vacation Southern Indiana offers a unique blend of nature, culture, and relaxation perfect for travelers seeking spa hotels. Begin your journey at the stunning Brown County State Park, known for its rolling hills and scenic trails—ideal for a morning hike or a leisurely bike ride. After a day outdoors, unwind at the local wineries, such as the Oliver Winery, where you can indulge in wine tastings and picturesque vineyard views. For a taste of history, visit the charming town of Nashville, filled with artisan shops and art galleries that showcase local talent. Don't miss the opportunity to explore the limestone caves at the Indiana Caverns, where guided tours reveal breathtaking underground formations. Finally, consider staying near the vibrant city of Bloomington, home to luxurious hotels with full-service spas, where you can pamper yourself with massages and rejuvenating treatments after a day of exploration. The region’s welcoming atmosphere and high-top hotels ensure an enriching experience that caters to your every comfort. ## Top Southern Indiana Hotel Reviews ![Drury Inn & Suites Evansville East](https://images.trvl-media.com/lodging/1000000/120000/116600/116545/2ba5f829_y.jpg) ### Drury Inn & Suites Evansville East 10/10 Excellent "I have stayed here a few times and it’s always great. " [](https://expedia.com/Evansville-Hotels-Drury-Inn-Suites-Evansville-East.h116545.Hotel-Information) ![Big Splash Adventure Indoor Water Park & Resort](https://images.trvl-media.com/lodging/5000000/4860000/4857100/4857069/7ae340db_y.jpg) ### Big Splash Adventure Indoor Water Park & Resort 4/10 Poor "The staff was wonderful but the rooms are outdated there was rust everywhere. The water was so cold u could only be in it for an hour. It was definitely much smaller then expected and the rooms dont come with the water park access u have to buy thise separately. The food was all microwave food except the pizza. Overall disappointing " [](https://expedia.com/French-Lick-Hotels-Big-Splash-Adventure-Indoor-Water-Park-Resort.h4857069.Hotel-Information) ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - [Pet-Friendly Hotels in Southwestern Indiana ](https://www.expedia.com/Southwestern-Indiana-Hotels-Pet-Friendly-Hotel.0-0-d6233876-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Hotels with Room Service in Southwestern Indiana ](https://www.expedia.com/Southwestern-Indiana-Hotels-Hotels-With-Room-Service.0-0-d6233876-tHotelswithRoomService.Travel-Guide-Filter-Hotels) - [Hotel Wedding Venues Hotels in Southwestern Indiana ](https://www.expedia.com/Southwestern-Indiana-Hotels-Wedding-Hotels.0-0-d6233876-tWeddingHotels.Travel-Guide-Filter-Hotels) - [Historic Hotels in Southwestern Indiana ](https://www.expedia.com/Southwestern-Indiana-Hotels-Historic-Hotel.0-0-d6233876-tHistoricHotel.Travel-Guide-Filter-Hotels) - [Casino Hotels in Southwestern Indiana ](https://www.expedia.com/Southwestern-Indiana-Hotels-Casino-Hotel.0-0-d6233876-tCasinoHotel.Travel-Guide-Filter-Hotels) - 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