St. James Vacations from $783

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Your St. James Vacation

Our vacation packages to St. James give you the power to customize your own adventure. Tailor your journey to your interests and style and make the most of your time in this lively city. Make your trip to St. James even more exciting by including some sightseeing. Maramec Spring Park, St. James Winery and Fall Creek Rock Shop are some of the leading attractions you'll want to explore. Whoever you're taking a break with and whatever you plan to spend, your dream St. James vacation is just a few clicks away with Expedia.

The Latest St. James vacation packages

Price found within the past 48 hours. Click for updated prices.
Capital O Amerihost Inn and Suites Fulton Hwy 54 MO

Capital O Amerihost Inn and Suites Fulton Hwy 54 MO

$783
per person
Dec 27 - Jan 2
found 1 day ago
Roundtrip non-stop flight included
Albuquerque (ABQ) to Columbia (COU)
5.6/10 (507 reviews)
First of all, I never leave a review good or bad, but this experience was that bad. Got there and they had overbooked. They said they had 5 rooms that had been overbooked due to computer issue. Lady at front desk, who smelled like alcohol, told me I could go to another hotel in the next town over. Eventually got a room there. Hotel smells like an ash tray, toilet seat was barely connected to the floor, one of the beds did not have a plastic sheet to protect against bugs, and the whole property smelled of pot. Carpet was disgustingly worn. I would definitely not stay here again unless you can get it for half as much as they think they are worth.

Reviewed on Oct 13, 2026

Capital O Amerihost Inn and Suites Mexico Hwy 54 MO

Capital O Amerihost Inn and Suites Mexico Hwy 54 MO

$788
per person
Dec 27 - Jan 2
found 1 day ago
Roundtrip non-stop flight included
Albuquerque (ABQ) to Columbia (COU)
5.6/10 (424 reviews)
I grew up in the area, and know how old the place is, and it has run down. Quite a bit. Lights flicker or not truly work, musty, beds need updated, along with bedding. ( Queen size on king size. Poor quality, you get what you pay for obviously, but ehhh.

Reviewed on Oct 10, 2026

Lake Life: Amazing Weekday Specials! Dock, Swim Mat, Cove Water

Lake Life: Amazing Weekday Specials! Dock, Swim Mat, Cove Water

$2,073
per person
Dec 27 - Jan 2
found 1 day ago
Roundtrip non-stop flight included
Albuquerque (ABQ) to Columbia (COU)
No reviews
Days Inn by Wyndham Mexico

Days Inn by Wyndham Mexico

$867
per person
Dec 27 - Jan 2
found 1 day ago
Roundtrip non-stop flight included
Albuquerque (ABQ) to Columbia (COU)
7/10 Good! (315 reviews)
I kind of missed seeing part of the breakfast, but we were actually rushed for time. The thing I didn’t like at all is the smell of carpet powder, which I’m allergic. Overall, it was very clean and staff were friendly.

Reviewed on Oct 13, 2026

Days Inn by Wyndham Kingdom City

Days Inn by Wyndham Kingdom City

$788
per person
Dec 27 - Jan 2
found 1 day ago
Roundtrip non-stop flight included
Albuquerque (ABQ) to Columbia (COU)
7/10 Good! (523 reviews)
OK for the basics. Clean room, comfortable bed. Check-in was weird, had to speak to a person on a screen on a kiosk. Communication somewhat difficult, but it went smoothly enough. But, honestly, would much rather check in with a person at the reception desk then try to make myself understood to someone speaking to me over a TV screen at a different location. Subsequent customers spoke to a different person on the kiosk, so was obvious we were being checked in by people at a call center. Would rather not repeat that experience.

Reviewed on Oct 14, 2026

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Stay near popular St. James attractions

Maramec Spring Park

9.4/10 (55 reviews)
This fifth-largest spring in Missouri produces 100 million gallons of water daily amid historic iron works ruins. Enjoy premium trout fishing or follow trails through lush woodlands to discover its serene natural beauty.
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St. James Winery

9.0/10 (61 reviews)
Missouri's largest winery offers over 40 award-winning wines and complimentary tastings in a picturesque setting. Relax in "The Gardens" with bocce courts and pair your wine with wood-fired pizza.
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Rosati Winery Museum

7.8/10 (6 reviews)
This intimate museum preserves the story of Italian winemakers who shaped Missouri's viticultural heritage. Explore vintage equipment and watch oral histories in the Reel Little Theater while sampling local wines.
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Meramec Vineyards

9.0/10 (9 reviews)
Taste award-winning wines crafted from Missouri's Ozark Highlands at this welcoming vineyard. Relax in the on-site restaurant or browse the gift shop for gourmet foods and wine accessories.
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Dry Fork Conservation Area

Explore 156 acres of diverse Missouri wilderness at this peaceful conservation area. Wander through forest trails while spotting local wildlife in this natural retreat from city life.
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St. James Hotel Deals

Greenlight Inn & Suites

Greenlight Inn & Suites

110 N Outer Rd St. James MO
Fully refundableReserve now, pay when you stay
$62 nightly
$70 total
Nov 16 - Nov 17
Total with taxes and fees
8.6/10 Excellent! (612 reviews)
"The stay was nice. The room was clean to the eye, however, saw a couple dead bugs (flies/knats) in sink and tub. The bathrooms door had wood coming off. The sheets and pillows were clean so that was a plus. The a/c kept going on and off even tho I had it set to stay on constant all night. Would just ..."

Reviewed on Oct 14, 2026

Greenlight Inn & Suites
Economy Inn

Economy Inn

102 N Outer Rd St. James MO
Fully refundableReserve now, pay when you stay
$50 nightly
$57 total
Oct 18 - Oct 19
Total with taxes and fees
Economy Inn
The Concord: A charming 2-bed 2-bath pet friendly house in historic Saint James

The Concord: A charming 2-bed 2-bath pet friendly house in historic Saint James

Saint James MO
$130 nightly
$137 total
Oct 20 - Oct 21
Total with taxes and fees
The Concord: A charming 2-bed 2-bath pet friendly house in historic Saint James
See all 231 properties in St. James
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best St. James Vacation Packages

St. James Essential Information

Language
English
Currency
U.S dollars
Population
4,200
Max Temp Winter
40ºF
Max Temp Summer
90ºF
Top Sights
The Fugitive Beach, St. James Winery and Cedar Street Playhouse

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Frequently asked questions

What are the top things to do in St. James?
A St. James vacation offers plenty of outdoor activities and natural beauty to explore. This outdoor and nature destination outside the city provides a variety of attractions:Browse and book things to do in St. James on Expedia.
How can I save money on a St. James vacation package?
When you bundle, you can save up to 30%*. To save money on a St. James package, consider traveling during the quieter months or be flexible with your dates to find more options. Bundling your flights and hotel together often unlocks savings compared to booking separately. *Members only. Savings vary.
Do you need to rent a car in St. James, or is public transport enough?
For a St. James vacation package, renting a car is highly recommended for exploring this outdoor and nature destination. St. James is about 85 miles from St. Louis Lambert International Airport (STL), and many of its attractions are spread out. For example, Maramec Spring Park is about 10 miles away, Montauk State Park is about 8 miles, and Mark Twain Lake is about 19 miles from central St. James. A car provides the flexibility to visit these scenic spots and the Fanning Route 66 Outpost, about 16 miles away, at your own pace.
Are St. James vacation package hotels conveniently located?
St. James vacation package hotels are generally well-located for exploring the area's outdoor attractions. For instance, Greenlight Inn & Suites, rated 8.3 out of 10, is conveniently situated about a 15-minute walk from central St. James. This makes it easy to access local points of interest and provides a good base for your adventures in this outdoor and nature destination.
Can I change or cancel my St. James vacation package if my plans change?
Yes, you can cancel your vacation package via your itinerary page on Expedia or by contacting customer service. Remember that some packages are fully refundable, but the details vary based on each unique booking. A fully refundable package may depend on how far out from the travel dates you're canceling and what airline you are traveling with.
Do One Key members get extra savings when booking St. James vacation packages?
Yes, members who join our free One Key™ travel rewards program can instantly unlock additional savings and save 10% or more on over 500,000 stays worldwide with Member Prices and over 1 million car rentals.
Does Expedia offer Book Now, Pay Later St. James vacation packages?
Yes, with Expedia's Book Now, Pay Later option, powered by Affirm, you can spread the cost of your St. James vacation over 3, 6, or 12 months. With no late payment fees or hidden costs, it's easy to secure your ideal vacation package as soon as you spot it.
How do I find last-minute vacation packages to St. James?
To find last-minute vacation packages to St. James, explore the last-minute deals section for the latest package offers, including flights, departing in the coming weeks. Being flexible with your travel dates and hotel preferences can help you secure the best prices.
How does free cancellation work on St. James vacation packages?
Free cancellation on a St. James vacation package depends on the specific hotel and rate combination you book. Many bookings allow free cancellation up to a stated deadline (often a few days before travel) where eligible. Read the cancellation terms carefully when reviewing the package, and visit Expedia help center for further details.
Is it cheaper to book a St. James vacation as a package or separately?
Booking flights and hotels together can unlock lower overall prices. Better still, you can tailor your St. James getaway to match your exact preference. Pick your preferred flight time, select the hotel type and add a car rental. Explore our bundles to see how much you can save.
Why should I book my St. James vacation package with Expedia?
Booking your vacation package on Expedia makes it easier to get more out of your trip from the start. With a wide choice of hotels, you can compare prices, reviews and amenities all in one place, then bundle your hotel with flights which could help you save even more. Flexible booking options on selected stays also make it easier to plan with confidence.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.