Tenderloin Vacations from $496

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Your Tenderloin Vacation

Our Tenderloin vacation packages are a time-saving and convenient way to organize and book your next exciting adventure. Discover the heart and soul of this unique neighborhood without the pressure of having to plan everything yourself. When it's time to sightsee, you'll find lots of popular attractions nearby including Pier 39, Alcatraz Island and Lombard Street. Visit one, two (or even all!) during your trip to Tenderloin. Stop dreaming and start doing. When it's time to book your dream vacation to Tenderloin, Expedia will help get you there.

The Latest Tenderloin Vacation Packages

Price found within the past 48 hours. Click for updated prices.
The Grove Inn

The Grove Inn

3 out of 5
Western Addition
Save 100% on your flight
Price was $815, price is now $496 per person
$496
per person
Sep 5 - Sep 8
found 22 hours ago
Roundtrip flight included
Burbank (BUR) to San Francisco (SFO)
9.2/10 Wonderful! (718 reviews)
Amazing stay for our wedding anniversary. Such a lovely Inn. Highly recommend!

Reviewed on Jun 13, 2026

Claremont Resort & Club

Claremont Resort & Club

5 out of 5
Claremont Hills
Save 100% on your flight
Price was $1,335, price is now $753 per person
$753
per person
Aug 10 - Aug 15
found 23 hours ago
Roundtrip flight included
Burbank (BUR) to Oakland (OAK)
9/10 Wonderful! (1,037 reviews)
Very nice place for our staycation

Reviewed on Jun 23, 2026

SF Central Hotel

SF Central Hotel

2 out of 5
Downtown San Francisco
Save 100% on your flight
Price was $1,092, price is now $628 per person
$628
per person
Sep 12 - Sep 19
found 1 day ago
Roundtrip flight included
Los Angeles (LAX) to San Francisco (SFO)
6.2/10 (885 reviews)
Good área, Good staff, safety área. Clean room😊

Reviewed on May 8, 2026

Treehouse Hotel Silicon Valley

Treehouse Hotel Silicon Valley

5 out of 5
Save 100% on your flight
Price was $3,042, price is now $1,775 per person
$1,775
per person
Aug 30 - Sep 5
found 1 day ago
Roundtrip flight included
Dallas (DFW) to San Francisco (SFO)
9.8/10 Exceptional! (101 reviews)
Just a beautiful place. Soooo much green everywhere! and it really had a special feel to it. pool temperature was really nice and warm ;-)

Reviewed on Jun 23, 2026

Vinarosa Resort & Spa

Vinarosa Resort & Spa

4 out of 5
Save 100% on your flight
Price was $1,845, price is now $1,118 per person
$1,118
per person
Jul 31 - Aug 5
found 1 day ago
Roundtrip flight included
Dallas (DFW) to San Francisco (SFO)
9.4/10 Exceptional! (884 reviews)
Gorgeous! Clean, comfortable, beautiful grounds. Close to the freeway but you would never know it. No noise from the roads. Great walk through the vineyards. Room was beautiful. Staff was great. Will be back!

Reviewed on Jun 22, 2026

Where to stay in Tenderloin

Find the best Tenderloin areas and neighborhoods for the activities you enjoy most. Learn more about Tenderloin
Fisherman's Wharf

Fisherman's Wharf

1 out of top 10 points of interest in this area
4/5(39 area reviews)

Discover Pier 39, Ghirardelli Square, and the San Francisco Maritime National Historical Park in this bustling tourist hotspot. Savor seafood at family-owned restaurants and explore the sea lion colony, while enjoying convenient cable car access.

Find hotels in Fisherman's Wharf

Tenderloin Hotel Deals

The Phoenix Hotel

The Phoenix Hotel

3 out of 5
601 Eddy St San Francisco CA
Fully refundableReserve now, pay when you stay
$155 nightly
The price is $183 total per night from Jul 5 to Jul 6
$183 total
Jul 5 - Jul 6
Total with taxes and fees
9/10 Wonderful! (1,001 reviews)
"Room is dated, needs a paint job. Lots of scuffs and worn out furniture. Bathroom and room wasn't very clean. Bed was alright. I don't recommend this hotel. The neighborhood isn't great as well. Centrally located for what I needed."

Reviewed on Jun 23, 2026

The Phoenix Hotel
Embassy Hotel

Embassy Hotel

2.5 out of 5
610 Polk St San Francisco CA
Fully refundableReserve now, pay when you stay
$90 nightly
The price is $106 total per night from Jun 30 to Jul 1
$106 total
Jun 30 - Jul 1
Total with taxes and fees
6.6/10 (849 reviews)
"I would not recommend this hotel. The room was not clean when we arrived, and there was a bad smell that made the stay uncomfortable. The room did not feel fresh or well maintained, and it was not the kind of place I would want to stay in again. For travelers looking for a clean and comfortable hotel, ..."

Reviewed on Jun 23, 2026

Embassy Hotel
Hyatt Regency San Francisco

Hyatt Regency San Francisco

4 out of 5
5 Embarcadero Center San Francisco CA
Fully refundableReserve now, pay when you stay
$218 nightly
The price is $257 total per night from Jul 12 to Jul 13
$257 total
Jul 12 - Jul 13
Total with taxes and fees
9.2/10 Wonderful! (2,312 reviews)
"It's bay facing but lot of buildings nearby as well. Location is great overall, course to restaurants, the pier and a Safeway toom"

Reviewed on Jun 23, 2026

Hyatt Regency San Francisco
See all 4,286 properties in Tenderloin
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in Tenderloin

Great American Music Hall

After visiting Great American Music Hall, make a plan to see the other sights and activities in San Francisco. Discover the fascinating museums and notable monuments in this vibrant area.

Great American Music Hall

Golden Gate Theatre

You can enjoy a show at Golden Gate Theatre during your trip to San Francisco. Experience the entertainment choices and acclaimed theater scene in this vibrant area.

Golden Gate Theatre

Things to do

Official Alcatraz Island Prison Tour with Free App Audio Packages

Official Alcatraz Inside Prison Tour with Free App Audio Packages

$86
per adult
100% of travellers recommend
Official Alcatraz Inside Prison Tour with Free App Audio Packages
California Academy of Sciences General Admission

California Academy of Sciences Daytime Admission

$49
per adult
86% of travellers recommend
California Academy of Sciences Daytime Admission
Alcatraz Visit with Night Option and SF Bay Cruise

Alcatraz Visit with Night Option and SF Bay Cruise

$125
per adult
94% of travellers recommend
Alcatraz Visit with Night Option and SF Bay Cruise
See all activities in San Francisco

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.