Name: Handlery Union Square Hotel
Price range: $164 total
Rating: 8.8

Your Tenderloin Vacation

Our Tenderloin vacation packages are a time-saving and convenient way to organize and book your next exciting adventure. Discover the heart and soul of this unique neighborhood without the pressure of having to plan everything yourself. When it's time to sightsee, you'll find lots of popular attractions nearby including Pier 39, Alcatraz Island and Lombard Street. Visit one, two (or even all!) during your trip to Tenderloin. Stop dreaming and start doing. When it's time to book your dream vacation to Tenderloin, Expedia will help get you there.

The Latest Tenderloin Vacation Packages

Price found within the past 48 hours. Click for updated prices.

Bay Landing San Francisco Airport Hotel

Ingold - Milldale

Save 100% on your flight

$383

per person

May 5 - May 10

found 1 day ago

Roundtrip flight included

Denver (DEN) to San Francisco (SFO)

9/10 Wonderful! (4,699 reviews)

The staff are amazing especially Ariel, she was so sweet and helpful!

Reviewed on Mar 2, 2026

The Grove Inn

Western Addition

Save 100% on your flight

$529

per person

May 5 - May 10

found 1 day ago

Roundtrip flight included

Denver (DEN) to San Francisco (SFO)

9.2/10 Wonderful! (670 reviews)

We had a deluxe king room. The room was small and basic, but sparkly clean and had a very comfortable bed. We really liked the location. It was very central to everything we wanted to do.

Reviewed on Feb 12, 2026

La Bahia Hotel and Spa

Westside Santa Cruz

$1,273

per person

May 2 - May 9

found 1 day ago

Roundtrip non-stop flight included

Denver (DEN) to San Jose (SJC)

9.6/10 Exceptional! (44 reviews)

Undoubtedly the best place in Santa Cruz. However I was surprized by the $50 resort fee and $50 daily parking.

Reviewed on Feb 28, 2026

Silverado Resort

Save 100% on your flight

$2,376

per person

May 21 - May 25

found 1 day ago

Roundtrip non-stop flight included

Denver (DEN) to Oakland (OAK)

8.8/10 Excellent! (1,053 reviews)

The staff was courteous. Our room was small but clean. The food and drink prices were outrageous.

Reviewed on Feb 23, 2026

Motel 6 Santa Cruz, CA

Westside Santa Cruz

$1,282

per person

May 2 - May 9

found 1 day ago

Roundtrip non-stop flight included

Denver (DEN) to San Jose (SJC)

6/10 (581 reviews)

Front desk staff too a long time to get to desk to help. Room was dark, smelt bad and shower did not work right.

Reviewed on Feb 22, 2026

Where to stay in Tenderloin

Find the best Tenderloin areas and neighborhoods for the activities you enjoy most. Learn more about Tenderloin

Union Square

4/5(5,164 area reviews)

Major tourist destination in downtown San Francisco, Union Square boasts shopping, hotels, and theaters. Explore department stores, boutiques, and galleries, or catch a performance at various theaters. Enjoy the Dewey Monument and stunning views from nearby hotels. Easily accessible via cable car lines, buses, and subway systems.

Fisherman's Wharf

1 out of top 10 points of interest in this area

4/5(38 area reviews)

Discover Pier 39, Ghirardelli Square, and the San Francisco Maritime National Historical Park in this bustling tourist hotspot. Savor seafood at family-owned restaurants and explore the sea lion colony, while enjoying convenient cable car access.

Downtown San Francisco

4 out of top 10 points of interest in this area

3/5(1,084 area reviews)

Serving as San Francisco's central business district, this area boasts Northern California's two tallest buildings, the Salesforce Tower and Transamerica Pyramid. Explore shopping malls like the Embarcadero Center and enjoy parks such as Sue Biermann Park, all easily accessible via Muni bus and rail lines.

Tenderloin Hotel Deals

Holiday Inn Golden Gateway by IHG

1500 Van Ness Ave San Francisco CA

Fully refundableReserve now, pay when you stay

$135 nightly

$159 total

Mar 29 - Mar 30

Total with taxes and fees

9/10 Wonderful! (5,346 reviews)

The location is great, it’s close to lots of attractions with upscale neighborhoods. Hotel services are excellent with friendly and charming staffs. Room is spacious and clean, well kept. I enjoyed my stay at Holiday Inn Golden Gateway a lot.

Reviewed on Mar 1, 2026

Hotel Riu Plaza Fisherman's Wharf

2500 Mason St San Francisco CA

Fully refundableReserve now, pay when you stay

$176 nightly

$208 total

Mar 3 - Mar 4

Total with taxes and fees

9/10 Wonderful! (7,339 reviews)

Everyone was kind and very helpful. The room was spotless when we checked in. Only stayed 2 nights so we didn’t have our room cleaned.

Reviewed on Mar 2, 2026

Handlery Union Square Hotel

351 Geary St San Francisco CA

Fully refundableReserve now, pay when you stay

$139 nightly

$164 total

Mar 31 - Apr 1

Total with taxes and fees

8.8/10 Excellent! (2,883 reviews)

Location is great and room (272) in general was OK. However, need improvement with the internet connection as it was very slow. We also had a problem with the shower, when the button that changes the water flow from the shower to the tub would automaticaly change, so it was an inconvenience to continue ...

Reviewed on Mar 2, 2026

See all 4,749 properties in Tenderloin

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.