Tenderloin Vacations from $204
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Your Tenderloin Vacation
Our Tenderloin vacation packages are a time-saving and convenient way to organize and book your next exciting adventure. Discover the heart and soul of this unique neighborhood without the pressure of having to plan everything yourself. When it's time to sightsee, you'll find lots of popular attractions nearby including Pier 39, Alcatraz Island and Lombard Street. Visit one, two (or even all!) during your trip to Tenderloin. Stop dreaming and start doing. When it's time to book your dream vacation to Tenderloin, Expedia will help get you there.
The Latest Tenderloin Vacation Packages
Cathedral Hill Hotel
Reviewed on Aug 7, 2026
Where to stay in Tenderloin
Fisherman's Wharf
Discover Pier 39, Ghirardelli Square, and the San Francisco Maritime National Historical Park in this bustling tourist hotspot. Savor seafood at family-owned restaurants and explore the sea lion colony, while enjoying convenient cable car access.
Union Square
Major tourist destination in downtown San Francisco, Union Square boasts shopping, hotels, and theaters. Explore department stores, boutiques, and galleries, or catch a performance at various theaters. Enjoy the Dewey Monument and stunning views from nearby hotels. Easily accessible via cable car lines, buses, and subway systems.
Downtown San Francisco
Serving as San Francisco's central business district, this area boasts Northern California's two tallest buildings, the Salesforce Tower and Transamerica Pyramid. Explore shopping malls like the Embarcadero Center and enjoy parks such as Sue Biermann Park, all easily accessible via Muni bus and rail lines.
South of Market
From baseball games to top-notch art exhibits, find endless entertainment in one of San Francisco’s fastest-growing neighborhoods.
Nob Hill
Luxury hotels, historic mansions, and Michelin-starred restaurants abound in this upscale area. Explore Union Square shopping district, Grace Cathedral, and the SF Masonic Auditorium for a taste of culture and history.
Tenderloin Hotel Deals
The Phoenix Hotel
Holiday Inn Golden Gateway by IHG
Hotel Riu Plaza Fisherman's Wharf
"Great location. Surprisingly quiet hotel for the number of rooms. Breakfast buffet was very good with lots of options. Short wait at times"
Reviewed on Aug 8, 2026
Stay near popular Tenderloin attractions
Great American Music Hall
Golden Gate Theatre
UC Law San Francisc
Things to do
Alcatraz Inside Prison Tour with Free App Audio Packages
California Academy of Sciences Daytime Admission
California Sunset Cruise (2-hours)
Explore a world of travel with Expedia
- Crocker Galleria
- Ghirardelli Chocolate Experience
- Golden Gate Bridge
- American Conservatory Theater
- Chinese Historical Society of America
- Mrs. Doubtfire House
- Conservatory of Flowers
- Japantown Vacations
- Transamerica Redwood Forest
- Jack Kerouac Alley
- Eleonore Austerer Gallery
- San Francisco Maritime National Historical Park
- Grace Cathedral
- Palace of Fine Arts
- Maiden Lane
- Commercial Street
- Civic Center Plaza
- San Francisco Federal Building
- United Nations Plaza
- Chinatown Vacations
- Alcatraz Island
- Mission San Francisco de Asís
- Columbus Tower
- California Academy of Sciences
- Transamerica Pyramid
- Marines Memorial Theater
- Van Ness Avenue
- Yerba Buena Gardens
- Greek Theater
- Muir Woods National Monument
- Wells Fargo History Museum
- Magowan's Infinite Mirror Maze
- Audium
- Ghirardelli Square
- Yerba Buena Center for the Arts
- Ripley's Believe It Or Not Museum
- National Shrine of Saint Francis of Assisi
- Walt Disney Family Museum
- Sf Playhouse
- Sf Armory
- St. Mary Square
- Union Square
- Full House House
- Aquarium of the Bay
- Coit Tower
- De Young Museum
- Fisherman's Wharf Vacations
- Westin St Francis Hotel Glass Elevators
- Pacific-Union Club
- Sf Masonic Auditorium
- Lotta's Fountain
- Kong Chow Temple
- Alamo Square
- Balmy Alley
- Union Square Vacations
- Baker Beach
- Dragon's Gate
- Children's Creativity Museum
- The Cannery at Del Monte Square
- Orpheum Theatre
- San Francisco Mint
- Moscone Convention Center
- Old St. Mary's Cathedral
- Westfield San Francisco Centre
- Civic Center Vacations
- San Francisco Vacations
- Ferry Building
- San Francisco City Hall
- Lombard Street
- San Francisco Zoo
- Golden Gate Theatre
- Warfield Theatre
- Yerba Buena Ice Skating Center
- Union Square Ice Rink
- Asian Art Museum of San Francisco
- Crissy Field
- Pier 39
- Palace Hotel
- Bill Graham Civic Auditorium
- Walter S. Johnson Park
- Downtown San Francisco Vacations
- St. Patrick Catholic Church
- Embarcadero Center
- The Regency Ballroom
- California Pacific Medical Center: Pacific Campus
- Cable Car Museum
- Cathedral of Saint Mary of the Assumption
- Saints Peter and Paul Church
- Chase Center
- 450 Sutter Building
- Musée Mécanique
- Uss Pampanito
- Museum of Craft and Folk Art
- San Francisco Museum of Modern Art
- Maxwell Galleries
- Telephone Pioneers Communication Museum
- Shn Curran Theatre
- Japanese Tea Garden
- 555 California Street