Name: Hyatt Regency San Francisco
Price range: $258 total
Rating: 9.2

Your Tenderloin Vacation

Our Tenderloin vacation packages are a time-saving and convenient way to organize and book your next exciting adventure. Discover the heart and soul of this unique neighborhood without the pressure of having to plan everything yourself. When it's time to sightsee, you'll find lots of popular attractions nearby including Pier 39, Alcatraz Island and Lombard Street. Visit one, two (or even all!) during your trip to Tenderloin. Stop dreaming and start doing. When it's time to book your dream vacation to Tenderloin, Expedia will help get you there.

The Latest Tenderloin Vacation Packages

Price found within the past 48 hours. Click for updated prices.

Bay Landing San Francisco Airport Hotel

Save 100% on your flight

$275

per person

Oct 4 - Oct 7

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to San Francisco (SFO)

9/10 Wonderful! (4,470 reviews)

It's was a great time staying there. The breakfast options are wide and tasty, the clean tables, and great view. Thank you staff for prompt service and availability. It was great, recommeding for 100%.

Reviewed on Aug 21, 2025

Aqua Breeze Inn

Westside Santa Cruz

$1,257

per person

Nov 6 - Nov 11

found 1 day ago

Roundtrip non-stop flight included

Dallas (DFW) to San Jose (SJC)

8/10 Very Good! (1,006 reviews)

This was a good place for a quick trip to Santa Cruz. We stayed with our family of 5 for one night. There was plenty of space for all of us. They only have stairs so if you need an elevator you would need to request the first floor. The place is a bit run down however, if the only thing you need is a clean place with a bed to sleep in then this will work for you. The walking distance to the boardwalk was great. It made it easy for us to come and go as needed. Our room was right by the patio on the second floor where people would hang out and smoke. I wasn’t a fan of that because we could smell it in the room. The beds were not super comfortable but you get what you get for the price.

Reviewed on Aug 15, 2025

The Grove Inn

Western Addition

Save 100% on your flight

$690

per person

Oct 22 - Oct 27

found 21 hours ago

Roundtrip flight included

Atlanta (ATL) to San Francisco (SFO)

9/10 Wonderful! (652 reviews)

Very nice property in a great location. Short walk to the painted laidies, restaurants and shops on Divisedero. Bus stop right there to take directly to the Fillmore, Castro, lower Haight, or the Mission.

Reviewed on Aug 7, 2025

Alila Napa Valley, a Hyatt Luxury Resort

Save 100% on your flight

$1,478

per person

Oct 26 - Oct 29

found 10 hours ago

Roundtrip flight included

Atlanta (ATL) to Oakland (OAK)

9.4/10 Exceptional! (107 reviews)

Great Vineyard view and staff was very accommodating!

Reviewed on Mar 20, 2025

Hotel Riu Plaza Fisherman's Wharf

Fisherman's Wharf

Save 100% on your flight

$432

per person

Oct 4 - Oct 7

found 1 day ago

Roundtrip flight included

Atlanta (ATL) to San Francisco (SFO)

9/10 Wonderful! (6,695 reviews)

Great location, breakfast was really good. Staff was really nice too, overall a good place to stay.

Reviewed on Aug 21, 2025

Where to stay in Tenderloin

Find the best Tenderloin areas and neighborhoods for the activities you enjoy most. Learn more about Tenderloin

Fisherman's Wharf

1 out of top 10 points of interest in this area

4/5(38 area reviews)

Discover Pier 39, Ghirardelli Square, and the San Francisco Maritime National Historical Park in this bustling tourist hotspot. Savor seafood at family-owned restaurants and explore the sea lion colony, while enjoying convenient cable car access.

Union Square

4/5(5,164 area reviews)

Major tourist destination in downtown San Francisco, Union Square boasts shopping, hotels, and theaters. Explore department stores, boutiques, and galleries, or catch a performance at various theaters. Enjoy the Dewey Monument and stunning views from nearby hotels. Easily accessible via cable car lines, buses, and subway systems.

Downtown San Francisco

3 out of top 10 points of interest in this area

3/5(1,084 area reviews)

Serving as San Francisco's central business district, this area boasts Northern California's two tallest buildings, the Salesforce Tower and Transamerica Pyramid. Explore shopping malls like the Embarcadero Center and enjoy parks such as Sue Biermann Park, all easily accessible via Muni bus and rail lines.

Tenderloin Hotel Deals

Hotel EPIK

706 Polk Street, San Francisco, CA

Fully refundable

$100 nightly

$118 total

Aug 25 - Aug 26

Total with taxes and fees

6.8/10 (443 reviews)

"Totally recommend. My absolute safe haven, and comfortable quiet place to be during the dead co celebratory weekend. Stayed four nights, no hitches, absolute convenience and access to everything San Francisco had to offer that weekend, super cool staff, friendly, clean, comfortable, quiet, affordable, ..."

Reviewed on Aug 9, 2025

Hotel Riu Plaza Fisherman's Wharf

2500 Mason St, San Francisco, CA

Fully refundableReserve now, pay when you stay

$148 nightly

$174 total

Aug 26 - Aug 27

Total with taxes and fees

8.8/10 Excellent! (6,684 reviews)

"The location and good service adds to the charm of the hotel."

Reviewed on Aug 20, 2025

Hyatt Regency San Francisco

5 Embarcadero Center, San Francisco, CA

Fully refundableReserve now, pay when you stay

$219 nightly

$258 total

Aug 28 - Aug 29

Total with taxes and fees

9.2/10 Wonderful! (1,807 reviews)

"Its nice and cozy. But i need to say this: water pressure was so bad. No sleepers"

Reviewed on Aug 18, 2025

See all 4,548 properties in Tenderloin

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.