Downtown San Francisco Vacations from $695

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to $1,045 when you book a flight and hotel together*

  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package

  • Rest easy

    Plan, book, and manage your trip all in one place

Your Downtown San Francisco Vacation

Experience everything Downtown San Francisco has to offer with a tailor-made Downtown San Francisco vacation package. From its history and shopping to its dining, prepare to be captivated by this busy neighborhood. When it's time to see the sights, you'll find plenty of big-name attractions nearby including Pier 39, Alcatraz Island and Lombard Street. Tick off one, two or all during your trip to Downtown San Francisco. Don't just think about it — turn it into reality! Book your ultimate Downtown San Francisco vacation with Expedia and experience travel your way.

The Latest Downtown San Francisco Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Bay Landing San Francisco Airport Hotel

Bay Landing San Francisco Airport Hotel

3 out of 5
Ingold - Milldale
Save 100% on your flight
Price was $1,197, price is now $695 per person
$695
per person
Jun 16 - Jun 21
found 1 day ago
Roundtrip flight included
Burbank (BUR) to San Francisco (SFO)
9/10 Wonderful! (4,822 reviews)
Convenient airport location, however shuttle service was limited, and desk staff misinformed when called about next pickup after landing. Had to take an Uber. Good breakfast, with cooked omelets, bacon and fruit.

Reviewed on Mar 22, 2026

The Marker Union Square San Francisco

The Marker Union Square San Francisco

4 out of 5
Union Square
Save 100% on your flight
Price was $1,419, price is now $868 per person
$868
per person
Jun 16 - Jun 21
found 1 day ago
Roundtrip flight included
Burbank (BUR) to San Francisco (SFO)
9.2/10 Wonderful! (1,203 reviews)
Great property staff very professional and courteous. Beautiful property and amenities!!! Definitely a special place to spend for vacation and business meetings in the city.

Reviewed on Mar 23, 2026

Club Wyndham Canterbury

Club Wyndham Canterbury

3 out of 5
Union Square
Save 100% on your flight
Price was $2,489, price is now $1,556 per person
$1,556
per person
Jun 16 - Jun 21
found 1 day ago
Roundtrip flight included
Burbank (BUR) to San Francisco (SFO)
9.2/10 Wonderful! (729 reviews)
Wonderful Everything was perfect ! Exceptional!!!

Reviewed on Mar 23, 2026

Handlery Union Square Hotel

Handlery Union Square Hotel

3.5 out of 5
Union Square
Save 100% on your flight
Price was $1,262, price is now $806 per person
$806
per person
Jun 16 - Jun 21
found 1 day ago
Roundtrip flight included
Burbank (BUR) to San Francisco (SFO)
8.8/10 Excellent! (2,922 reviews)
Great location, nice rooms. Yhe pool was closed when we were there due a delay in renovations, which was disappointing. But everything else was good.

Reviewed on Mar 23, 2026

Hotel Riu Plaza Fisherman's Wharf

Hotel Riu Plaza Fisherman's Wharf

4 out of 5
Fisherman's Wharf
Save 100% on your flight
Price was $1,499, price is now $960 per person
$960
per person
Jun 12 - Jun 16
found 1 day ago
Roundtrip flight included
Burbank (BUR) to San Francisco (SFO)
9/10 Wonderful! (7,413 reviews)
Wow, this place was incredible, the location truly was the absolute BEST, walking distance from all the fun. Everything was wonderful: morning breakfast buffet, room size and cleanliness, 10/10 for me and my family of 5!

Reviewed on Mar 23, 2026

Where to stay in Downtown San Francisco

Find the best Downtown San Francisco areas and neighborhoods for the activities you enjoy most. Learn more about Downtown San Francisco
Vibrant activity in Union Square, San Francisco with palm trees and bustling city life

Union Square

4/5(5,185 area reviews)

Major tourist destination in downtown San Francisco, Union Square boasts shopping, hotels, and theaters. Explore department stores, boutiques, and galleries, or catch a performance at various theaters. Enjoy the Dewey Monument and stunning views from nearby hotels. Easily accessible via cable car lines, buses, and subway systems.

Find hotels in Union Square

Downtown San Francisco Hotel Deals

Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave San Francisco CA
Fully refundableReserve now, pay when you stay
$132 nightly
The price is $155 total per night from Apr 12 to Apr 13
$155 total
Apr 12 - Apr 13
Total with taxes and fees
9/10 Wonderful! (5,440 reviews)
Clean room

Reviewed on Mar 23, 2026

Holiday Inn Golden Gateway by IHG
Handlery Union Square Hotel

Handlery Union Square Hotel

3.5 out of 5
351 Geary St San Francisco CA
Fully refundableReserve now, pay when you stay
$149 nightly
The price is $176 total per night from Mar 27 to Mar 28
$176 total
Mar 27 - Mar 28
Total with taxes and fees
8.8/10 Excellent! (2,931 reviews)
Great location, nice rooms. Yhe pool was closed when we were there due a delay in renovations, which was disappointing. But everything else was good.

Reviewed on Mar 23, 2026

Handlery Union Square Hotel
YOTEL San Francisco

YOTEL San Francisco

3 out of 5
1095 Market St San Francisco CA
Fully refundableReserve now, pay when you stay
$103 nightly
The price is $122 total per night from Mar 31 to Apr 1
$122 total
Mar 31 - Apr 1
Total with taxes and fees
8.2/10 Very Good! (1,013 reviews)
Great place if you want to be somewhere convenient. Stayed here for a concert at Bill Graham. Small rooms, so they’re good if you plan on justbut efficient rooms

Reviewed on Mar 23, 2026

YOTEL San Francisco
See all 1,001 properties in Downtown San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in Downtown San Francisco

Oracle Park featuring a bay or harbor and street scenes as well as a small group of people

Oracle Park

4.5/5(1,461 reviews)

Whether or not you’re a baseball fan, this charming ballpark with outstanding views should be on your San Francisco sightseeing list.

Oracle Park
yerba buena gardens complex

Moscone Convention Center

4/5(601 reviews)

During your trip, find out what's happening at Moscone Convention Center, a top convention center in San Francisco. Discover the acclaimed art scene and notable monuments in this vibrant area.

Moscone Convention Center
Chase Center San Francisco Skyline Aerial Photography

Chase Center

Catch an event at Chase Center during your trip to San Francisco. Amble around this vibrant area's Chinatown or experience its entertainment choices.

Chase Center

Things to do

Alcatraz Island Prison Tour Package

Official Alcatraz Island Prison Tour with Free App Audio Packages

$86
per adult
100% of travellers recommend
Official Alcatraz Island Prison Tour with Free App Audio Packages
California Academy of Sciences General Admission

California Academy of Sciences Daytime Admission

$49
per adult
86% of travellers recommend
California Academy of Sciences Daytime Admission
Alcatraz San Francisco Bay Cruise with Night Option

Alcatraz Visit with Night Option and SF Bay Cruise

$139
per adult
94% of travellers recommend
Alcatraz Visit with Night Option and SF Bay Cruise
See all activities in San Francisco

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.