Downtown San Francisco Vacations from $885

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Your Downtown San Francisco Vacation

Experience everything Downtown San Francisco has to offer with a tailor-made Downtown San Francisco vacation package. From its history and shopping to its dining, prepare to be captivated by this busy neighborhood. When it's time to see the sights, you'll find plenty of big-name attractions nearby including Pier 39, Alcatraz Island and Lombard Street. Tick off one, two or all during your trip to Downtown San Francisco. Don't just think about it — turn it into reality! Book your ultimate Downtown San Francisco vacation with Expedia and experience travel your way.

The Latest Downtown San Francisco Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Bay Landing San Francisco Airport Hotel

Bay Landing San Francisco Airport Hotel

3 out of 5
Ingold - Milldale
Save 100% on your flight
Price was $1,365, price is now $885 per person
$885
per person
May 31 - Jun 7
found 21 hours ago
Roundtrip flight included
Dallas (DAL) to San Francisco (SFO)
9/10 Wonderful! (4,822 reviews)
Great location with a beautiful view of the bay and minimal airport noise. Decent and well-staffed breakfast to start your day. The staff was excellent and always willing to help! I hope they continue to keep it updated and clean, as it's a rare and affordable find.

Reviewed on Mar 18, 2026

Silverado Resort

Silverado Resort

4 out of 5
Save 100% on your flight
Price was $4,302, price is now $2,708 per person
$2,708
per person
May 22 - May 28
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Oakland (OAK)
8.8/10 Excellent! (1,103 reviews)
Room to small air unit did not work had to call emgino

Reviewed on Mar 15, 2026

Motel 6 Santa Cruz, CA

Motel 6 Santa Cruz, CA

2 out of 5
Westside Santa Cruz
Save 100% on your flight
Price was $1,484, price is now $937 per person
$937
per person
May 18 - May 23
found 17 hours ago
Roundtrip flight included
Seattle (SEA) to San Jose (SJC)
6/10 (612 reviews)
Front desk staff too a long time to get to desk to help. Room was dark, smelt bad and shower did not work right.

Reviewed on Feb 22, 2026

@ Marbella Lane - Modern Refreshing Home

@ Marbella Lane - Modern Refreshing Home

3 out of 5
North Central
Save 100% on your flight
Price was $3,397, price is now $2,178 per person
$2,178
per person
May 28 - Jun 3
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to San Francisco (SFO)
No reviews
@ Marbella Lane - Natural Bayview Escape Near SFO

@ Marbella Lane - Natural Bayview Escape Near SFO

3 out of 5
Colma
Save 100% on your flight
Price was $2,135, price is now $1,425 per person
$1,425
per person
May 28 - Jun 3
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to San Francisco (SFO)
No reviews

Where to stay in Downtown San Francisco

Find the best Downtown San Francisco areas and neighborhoods for the activities you enjoy most. Learn more about Downtown San Francisco
Vibrant activity in Union Square, San Francisco with palm trees and bustling city life

Union Square

4/5(5,164 area reviews)

Major tourist destination in downtown San Francisco, Union Square boasts shopping, hotels, and theaters. Explore department stores, boutiques, and galleries, or catch a performance at various theaters. Enjoy the Dewey Monument and stunning views from nearby hotels. Easily accessible via cable car lines, buses, and subway systems.

Find hotels in Union Square

Downtown San Francisco Hotel Deals

Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave San Francisco CA
Fully refundableReserve now, pay when you stay
$132 nightly
The price is $155 total per night from Apr 12 to Apr 13
$155 total
Apr 12 - Apr 13
Total with taxes and fees
9/10 Wonderful! (5,417 reviews)
Staff top notch. Cleanliness in common areas ok, WiFi spotty, pool is beautiful at sunset

Reviewed on Mar 18, 2026

Holiday Inn Golden Gateway by IHG
Handlery Union Square Hotel

Handlery Union Square Hotel

3.5 out of 5
351 Geary St San Francisco CA
Fully refundableReserve now, pay when you stay
$136 nightly
The price is $160 total per night from Mar 21 to Mar 22
$160 total
Mar 21 - Mar 22
Total with taxes and fees
8.8/10 Excellent! (2,928 reviews)
We booked this hotel because of the pool but it was out of order for our stay. The rooms were cramped. AC didn’t work. Would not recommend

Reviewed on Mar 18, 2026

Handlery Union Square Hotel
YOTEL San Francisco

YOTEL San Francisco

3 out of 5
1095 Market St San Francisco CA
Fully refundableReserve now, pay when you stay
$107 nightly
The price is $126 total per night from Mar 31 to Apr 1
$126 total
Mar 31 - Apr 1
Total with taxes and fees
8.2/10 Very Good! (1,002 reviews)
Staff was excellent. Property was nice, rooms were pretty small but comfortable and clean. My only gripe was the lack of a fridge or in room microwave or something. Not the end of the world, but definitely a small bummer. Neighborhood isn't as bad as others review, it's just San francisco. I just ...

Reviewed on Mar 18, 2026

YOTEL San Francisco
See all 1,004 properties in Downtown San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in Downtown San Francisco

Oracle Park featuring a bay or harbor and street scenes as well as a small group of people

Oracle Park

4.5/5(1,454 reviews)

Whether or not you’re a baseball fan, this charming ballpark with outstanding views should be on your San Francisco sightseeing list.

Oracle Park
yerba buena gardens complex

Moscone Convention Center

4/5(598 reviews)

During your trip, find out what's happening at Moscone Convention Center, a top convention center in San Francisco. Discover the acclaimed art scene and notable monuments in this vibrant area.

Moscone Convention Center
Chase Center San Francisco Skyline Aerial Photography

Chase Center

Catch an event at Chase Center during your trip to San Francisco. Amble around this vibrant area's Chinatown or experience its entertainment choices.

Chase Center

Things to do

Alcatraz Island Prison Tour Package

Official Alcatraz Island Prison Tour with Free App Audio Packages

$86
per adult
100% of travellers recommend
Official Alcatraz Island Prison Tour with Free App Audio Packages
California Academy of Sciences General Admission

California Academy of Sciences Daytime Admission

$49
per adult
86% of travellers recommend
California Academy of Sciences Daytime Admission
Alcatraz San Francisco Bay Cruise with Night Option

Alcatraz Visit with Night Option and SF Bay Cruise

$139
per adult
94% of travellers recommend
Alcatraz Visit with Night Option and SF Bay Cruise
See all activities in San Francisco

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.