Downtown San Francisco Vacations from $354
Book a Hotel + Flight or Car together to unlock savings
Your Downtown San Francisco Vacation
Experience everything Downtown San Francisco has to offer with a tailor-made Downtown San Francisco vacation package. From its history and shopping to its dining, prepare to be captivated by this busy neighborhood. When it's time to see the sights, you'll find plenty of big-name attractions nearby including Pier 39, Alcatraz Island and Lombard Street. Tick off one, two or all during your trip to Downtown San Francisco. Don't just think about it — turn it into reality! Book your ultimate Downtown San Francisco vacation with Expedia and experience travel your way.
The Latest Downtown San Francisco Vacation Packages
Price found within the past 48 hours. Click for updated prices.
SOMA Park Inn – Civic Center
Downtown San Francisco
Save 100% on your flight
Price was $564, price is now $354 per person
$354
per person
May 12 - May 17
found 1 day ago
Roundtrip flight included
Dallas (DFW) to San Francisco (SFO)
6.8/10 (1,002 reviews)
Nice place to stay. Very friendly staff.
Reviewed on Feb 1, 2026
Motel 6 Santa Cruz, CA
Westside Santa Cruz
Save 100% on your flight
Price was $1,011, price is now $647 per person
$647
per person
May 22 - May 25
found 1 day ago
Roundtrip flight included
Seattle (SEA) to San Jose (SJC)
6/10 (612 reviews)
Front desk staff too a long time to get to desk to help.
Room was dark, smelt bad and shower did not work right.
Reviewed on Feb 22, 2026
1 Hotel San Francisco
Downtown San Francisco
Save 100% on your flight
Price was $2,447, price is now $1,580 per person
$1,580
per person
Jun 14 - Jun 17
found 14 hours ago
Roundtrip flight included
Burbank (BUR) to San Francisco (SFO)
9.2/10 Wonderful! (525 reviews)
Everything was beyond great!
Reviewed on Mar 30, 2026
Where to stay in Downtown San Francisco
Find the best Downtown San Francisco areas and neighborhoods for the activities you enjoy most. Learn more about Downtown San Francisco
Fisherman's Wharf
1 out of top 10 points of interest in this area
4/5(39 area reviews)
Discover Pier 39, Ghirardelli Square, and the San Francisco Maritime National Historical Park in this bustling tourist hotspot. Savor seafood at family-owned restaurants and explore the sea lion colony, while enjoying convenient cable car access.
Downtown San Francisco Hotel Deals
Holiday Inn Golden Gateway by IHG
1500 Van Ness Ave San Francisco CA
Fully refundableReserve now, pay when you stay
$132 nightly
The price is $155 total per night from Apr 12 to Apr 13
$155 total
Apr 12 - Apr 13
Total with taxes and fees
9/10 Wonderful! (5,500 reviews)
Breakfast was good, but thought it was included originally with stay. Also didnt know we had to pay for parking garage.
Reviewed on Apr 4, 2026
Handlery Union Square Hotel
351 Geary St San Francisco CA
Fully refundableReserve now, pay when you stay
$132 nightly
The price is $155 total per night from Apr 9 to Apr 10
$155 total
Apr 9 - Apr 10
Total with taxes and fees
8.8/10 Excellent! (2,950 reviews)
The hotel is an older hotel that is well maintained. The staff is very nice, friendly, polite and helpful. My only negative is that their is no restaurant and the website has not been updated to reflect that fact.
Reviewed on Apr 4, 2026
YOTEL San Francisco
1095 Market St San Francisco CA
Fully refundableReserve now, pay when you stay
$96 nightly
The price is $113 total per night from Apr 5 to Apr 6
$113 total
Apr 5 - Apr 6
Total with taxes and fees
8.2/10 Very Good! (1,008 reviews)
Went out did not visit the restaurant
Reviewed on Apr 3, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Downtown San Francisco
Oracle Park
Whether or not you’re a baseball fan, this charming ballpark with outstanding views should be on your San Francisco sightseeing list.
Moscone Convention Center
During your trip, find out what's happening at Moscone Convention Center, a top convention center in San Francisco. Discover the acclaimed art scene and notable monuments in this vibrant area.
Chase Center
Catch an event at Chase Center during your trip to San Francisco. Amble around this vibrant area's Chinatown or experience its entertainment choices.
Things to do
Official Alcatraz Island Prison Tour with Free App Audio Packages
$86
per adult
100% of travellers recommend
California Academy of Sciences Daytime Admission
$49
per adult
86% of travellers recommend
Alcatraz Visit with Night Option and SF Bay Cruise
$139
per adult
94% of travellers recommend
Explore a world of travel with Expedia
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- San Francisco Vacations
- Grace Cathedral
- San Francisco Museum of Modern Art
- Warfield Theatre
- San Francisco City Hall
- Golden Gate Theatre
- Shn Curran Theatre
- Visit San Francisco
- American Conservatory Theater
- Luggage Store Gallery
- Westin St Francis Hotel Glass Elevators
- Union Square Vacations
- Lorraine Hansberry Theatre
- Embarcadero Center
- San Francisco Magic Parlor
- Maxwell Galleries
- Sf Playhouse
- Eleonore Austerer Gallery
- Maiden Lane
- United Nations Plaza
- San Francisco Federal Building
- Yerba Buena Gardens
- Xanadu Gallery
- 450 Sutter Building
- Orpheum Theatre
- Westfield Metreon
- Asian Art Museum of San Francisco
- Sf Masonic Auditorium
- Pacific-Union Club
- Great American Music Hall
- Lotta's Fountain
- Children's Creativity Museum
- Visit Union Square
- Moscone Convention Center
- Civic Center Plaza
- Louise Davies Symphony Hall
- Where to stay in San Francisco
- Van Ness Avenue
- Sf Camerawork
- Palace Hotel
- Bill Graham Civic Auditorium
- Crocker Galleria
- Yerba Buena Ice Skating Center
- Crocker Bank Building
- The Museum Store
- St. Mary Square
- Cable Car Museum
- The Regency Ballroom
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.