Downtown San Francisco Vacations from $363

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Your Downtown San Francisco Vacation

Experience everything Downtown San Francisco has to offer with a tailor-made Downtown San Francisco vacation package. From its history and shopping to its dining, prepare to be captivated by this busy neighborhood. When it's time to see the sights, you'll find plenty of big-name attractions nearby including Pier 39, Alcatraz Island and Lombard Street. Tick off one, two or all during your trip to Downtown San Francisco. Don't just think about it — turn it into reality! Book your ultimate Downtown San Francisco vacation with Expedia and experience travel your way.

The Latest Downtown San Francisco Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Aqua Breeze Inn
Stanford Court San Francisco
Sutter Mansion
1 Hotel San Francisco
Hotel Riu Plaza Fisherman's Wharf

Where to stay in Downtown San Francisco

Find the best Downtown San Francisco areas and neighborhoods for the activities you enjoy most. Learn more about Downtown San Francisco

Downtown San Francisco Hotel Deals

Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave San Francisco CA
$119 nightly
The price is $140 total per night from Nov 29 to Nov 30
$140 total
Nov 29 - Nov 30
Total with taxes and fees
9/10 Wonderful! (6,491 reviews)
"The location is excellent, right at the edge of Nob Hill, with a cable car line and a Big Bus tour stop just nearby, making it very convenient to explore downtown. Japantown is also within walking distance. The hotel itself was clean, comfortable, and well maintained. Overall, a great place to stay ..."

Reviewed on Nov 13, 2026

Holiday Inn Golden Gateway by IHG
Hilton San Francisco Union Square

Hilton San Francisco Union Square

4 out of 5
333 O'Farrell St. San Francisco CA
$171 nightly
The price is $202 total per night from Nov 29 to Nov 30
$202 total
Nov 29 - Nov 30
Total with taxes and fees
Hilton San Francisco Union Square
FOUND Hotel Carlton, Nob Hill

FOUND Hotel Carlton, Nob Hill

2 out of 5
1075 Sutter St San Francisco CA
$78 nightly
The price is $92 total per night from Dec 15 to Dec 16
$92 total
Dec 15 - Dec 16
Total with taxes and fees
8.6/10 Excellent! (2,051 reviews)
"Very low price, would definitely come back."

Reviewed on Nov 14, 2026

FOUND Hotel Carlton, Nob Hill
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Downtown San Francisco attractions

Things to do

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.