Downtown San Francisco Vacations from $372
Book a Hotel + Flight or Car together to unlock savings
Your Downtown San Francisco Vacation
Experience everything Downtown San Francisco has to offer with a tailor-made Downtown San Francisco vacation package. From its history and shopping to its dining, prepare to be captivated by this busy neighborhood. When it's time to see the sights, you'll find plenty of big-name attractions nearby including Pier 39, Alcatraz Island and Lombard Street. Tick off one, two or all during your trip to Downtown San Francisco. Don't just think about it — turn it into reality! Book your ultimate Downtown San Francisco vacation with Expedia and experience travel your way.
The Latest Downtown San Francisco Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Hotel Riu Plaza Fisherman's Wharf
Fisherman's Wharf
Price was $600, price is now $372 per person
$372
per person
Jan 20 - Jan 24
found 1 day ago
Roundtrip flight included
Los Angeles (LAX) to San Francisco (SFO)
9/10 Wonderful! (7,739 reviews)
Very nice hotel and staff. Awesome breakfast buffet. Very small bathroom. A lot of security
Reviewed on Nov 13, 2026
The Grove Inn
Western Addition
Price was $708, price is now $425 per person
$425
per person
Jan 15 - Jan 18
found 1 day ago
Roundtrip flight included
Los Angeles (LAX) to San Francisco (SFO)
9.2/10 Wonderful! (747 reviews)
This inn was great! Peaceful and cozy rooms with nice amenities. My husband and I enjoyed our stay here!
Reviewed on Nov 12, 2026
Where to stay in Downtown San Francisco
Find the best Downtown San Francisco areas and neighborhoods for the activities you enjoy most. Learn more about Downtown San Francisco
Union Square
Major tourist destination in downtown San Francisco, Union Square boasts shopping, hotels, and theaters. Explore department stores, boutiques, and galleries, or catch a performance at various theaters. Enjoy the Dewey Monument and stunning views from nearby hotels. Easily accessible via cable car lines, buses, and subway systems.
Downtown San Francisco Hotel Deals
Holiday Inn Golden Gateway by IHG
1500 Van Ness Ave San Francisco CA
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $140 total per night from Nov 29 to Nov 30
$140 total
Nov 29 - Nov 30
Total with taxes and fees
9/10 Wonderful! (6,491 reviews)
"The location is excellent, right at the edge of Nob Hill, with a cable car line and a Big Bus tour stop just nearby, making it very convenient to explore downtown. Japantown is also within walking distance. The hotel itself was clean, comfortable, and well maintained. Overall, a great place to stay ..."
Reviewed on Nov 13, 2026
Hilton San Francisco Union Square
333 O'Farrell St. San Francisco CA
Fully refundableReserve now, pay when you stay
$147 nightly
The price is $173 total per night from Nov 29 to Nov 30
$173 total
Nov 29 - Nov 30
Total with taxes and fees
8.6/10 Excellent! (1,907 reviews)
"microwave in room would have been nice, apart from that everything else was excellend."
Reviewed on Nov 13, 2026
FOUND Hotel Carlton, Nob Hill
1075 Sutter St San Francisco CA
Fully refundableReserve now, pay when you stay
$82 nightly
The price is $97 total per night from Nov 29 to Nov 30
$97 total
Nov 29 - Nov 30
Total with taxes and fees
8.6/10 Excellent! (2,050 reviews)
"Excelente hospedaje. Ubicación estratégica en mi viaje a San Francisco!! Fácil acceso a transporte público. Zona segura y silenciosa . Habitaciones espaciosas , limpias , con todo lo necesario y cómodas sin duda , Olvera dmd y"
Reviewed on Nov 13, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Downtown San Francisco attractions
Things to do
Alcatraz Inside tour with Round trip ferry & Audio App Packages
$86
per adult
94% of travellers recommend
California Academy of Sciences Daytime Admission
$49
per adult
86% of travellers recommend
Alcatraz Visit with Night Option and SF Bay Cruise
$139
per adult
94% of travellers recommend
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.