Downtown San Francisco Vacations from $419
Book a Hotel + Flight or Car together to unlock savings
- Plan, book, travel with confidence
- Better togetherSave up to $1,045 when you book a flight and hotel together*
- Find the right fitWith over 300,000 hotels worldwide, it's easy to create a perfect package
- Rest easyPlan, book, and manage your trip all in one place
Your Downtown San Francisco Vacation
Experience everything Downtown San Francisco has to offer with a tailor-made Downtown San Francisco vacation package. From its history and shopping to its dining, prepare to be captivated by this busy neighborhood. When it's time to see the sights, you'll find plenty of big-name attractions nearby including Pier 39, Alcatraz Island and Lombard Street. Tick off one, two or all during your trip to Downtown San Francisco. Don't just think about it — turn it into reality! Book your ultimate Downtown San Francisco vacation with Expedia and experience travel your way.
The Latest Downtown San Francisco Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Hotel Zeppelin San Francisco
Union Square
Save 100% on your flight
Price was $643, price is now $419 per person
$419
per person
May 14 - May 17
found 1 day ago
Roundtrip non-stop flight included
Dallas (DFW) to San Francisco (SFO)
8.6/10 Excellent! (1,008 reviews)
Old building. Lots of noise. Extra charges. The only thing it is eclectic
Reviewed on Mar 21, 2026
Bay Landing San Francisco Airport Hotel
Ingold - Milldale
Save 100% on your flight
Price was $775, price is now $469 per person
$469
per person
May 19 - May 24
found 1 day ago
Roundtrip flight included
Burbank (BUR) to San Francisco (SFO)
9/10 Wonderful! (4,833 reviews)
Breakfast was fresh and ready! Staff was very nice and room was clean. Our stay went very 👌 I would recommend this hotel.
Reviewed on Mar 31, 2026
Hotel Riu Plaza Fisherman's Wharf
Fisherman's Wharf
Save 100% on your flight
Price was $1,048, price is now $661 per person
$661
per person
May 19 - May 24
found 1 day ago
Roundtrip flight included
Burbank (BUR) to San Francisco (SFO)
9/10 Wonderful! (7,413 reviews)
Staff are very helpful and honest.
The breakfast is superb.
Parking fee is pricey
Reviewed on Apr 2, 2026
Hotel Zephyr San Francisco
Fisherman's Wharf
Save 100% on your flight
Price was $898, price is now $586 per person
$586
per person
May 19 - May 24
found 1 day ago
Roundtrip flight included
Burbank (BUR) to San Francisco (SFO)
8.6/10 Excellent! (2,464 reviews)
Bathrooms are awkwardly small and double bed rooms were also smaller than expected. Ended up in a downsized room from what we reserved and expected. The industrial adult playground aspect of the common area wasn't as interesting as the listing makes it seem. Above average location, but value overall isn't great due to cost per night. Not super impressed and we won't stay here again.
Reviewed on Apr 2, 2026
Where to stay in Downtown San Francisco
Find the best Downtown San Francisco areas and neighborhoods for the activities you enjoy most. Learn more about Downtown San Francisco
Fisherman's Wharf
1 out of top 10 points of interest in this area
4/5(39 area reviews)
Discover Pier 39, Ghirardelli Square, and the San Francisco Maritime National Historical Park in this bustling tourist hotspot. Savor seafood at family-owned restaurants and explore the sea lion colony, while enjoying convenient cable car access.
Downtown San Francisco Hotel Deals
Holiday Inn Golden Gateway by IHG
1500 Van Ness Ave San Francisco CA
Fully refundableReserve now, pay when you stay
$132 nightly
The price is $155 total per night from Apr 12 to Apr 13
$155 total
Apr 12 - Apr 13
Total with taxes and fees
Handlery Union Square Hotel
351 Geary St San Francisco CA
Fully refundableReserve now, pay when you stay
$138 nightly
The price is $163 total per night from Apr 4 to Apr 5
$163 total
Apr 4 - Apr 5
Total with taxes and fees
8.8/10 Excellent! (2,957 reviews)
I don’t believe the room was worth the price.
Reviewed on Apr 2, 2026
YOTEL San Francisco
1095 Market St San Francisco CA
Fully refundableReserve now, pay when you stay
$83 nightly
The price is $98 total per night from Apr 7 to Apr 8
$98 total
Apr 7 - Apr 8
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Downtown San Francisco
Oracle Park
4.5/5(1,481 reviews)
Whether or not you’re a baseball fan, this charming ballpark with outstanding views should be on your San Francisco sightseeing list.
Moscone Convention Center
4/5(606 reviews)
During your trip, find out what's happening at Moscone Convention Center, a top convention center in San Francisco. Discover the acclaimed art scene and notable monuments in this vibrant area.
Chase Center
Catch an event at Chase Center during your trip to San Francisco. Amble around this vibrant area's Chinatown or experience its entertainment choices.
Things to do
California Academy of Sciences Daytime Admission
$49
per adult
86% of travellers recommend
Official Alcatraz Island Prison Tour with Free App Audio Packages
$86
per adult
100% of travellers recommend
Alcatraz Visit with Night Option and SF Bay Cruise
$139
per adult
94% of travellers recommend
Explore a world of travel with Expedia
- San Francisco Hotels
- Cheap Hotels in San Francisco
- Hotels with Free Airport Shuttle in San Francisco
- Hotels near Union Square
- Hotels with Free Parking in San Francisco
- Destination Hotels in San Francisco
- Pet-Friendly Hotels in San Francisco
- Oceanfront Hotels in San Francisco
- Extended Stay Hotels in San Francisco
- Motels in San Francisco
- All-Inclusive Resorts in San Francisco
- 5 Star Hotels in San Francisco
- Hotels near Moscone Convention Center
- Hotels with Kitchenettes in San Francisco
- Motel 6 Hotels in San Francisco
- Luxury Hotels in San Francisco
- Hotels with Early Check-in in San Francisco
- Hotels with a View in San Francisco
- Marriott Hotels & Resorts in San Francisco
- Hotels near Glide Memorial United Methodist Church
- Hotels near Warfield Theatre
- Hostels in San Francisco
- Family Hotels in San Francisco
- Hotels with an Indoor Pool in San Francisco
- B&B in San Francisco
- 4 Star Hotels in San Francisco
- Beach Hotels in San Francisco
- Casino Hotels in San Francisco
- Hotels near Golden Gate Theatre
- Romantic Hotels in San Francisco
- Best Western Hotels in San Francisco
- Hotels near Oracle Park
- Hotels with Balconies in San Francisco
- Hotels with a Pool in San Francisco
- Hotels with Free Breakfast in San Francisco
- Hotels near Marrakech Magic Theater
- Hotels with Hot Tubs in San Francisco
- Historic Hotels in San Francisco
- Kimpton Hotels in San Francisco
- Hotels with Kitchenettes in Union Square
- Hotels near San Franciscso Vistors Information Center
- Hotels near Powell St & Market St Stop
- Resorts & Hotels with Spas in San Francisco
- San Francisco Vacations
- Grace Cathedral
- San Francisco Museum of Modern Art
- Warfield Theatre
- San Francisco City Hall
- Golden Gate Theatre
- Shn Curran Theatre
- Visit San Francisco
- American Conservatory Theater
- Luggage Store Gallery
- Westin St Francis Hotel Glass Elevators
- Union Square Vacations
- Lorraine Hansberry Theatre
- Embarcadero Center
- San Francisco Magic Parlor
- Maxwell Galleries
- Sf Playhouse
- Eleonore Austerer Gallery
- Maiden Lane
- United Nations Plaza
- San Francisco Federal Building
- Yerba Buena Gardens
- Xanadu Gallery
- 450 Sutter Building
- Orpheum Theatre
- Westfield Metreon
- Asian Art Museum of San Francisco
- Sf Masonic Auditorium
- Pacific-Union Club
- Great American Music Hall
- Lotta's Fountain
- Children's Creativity Museum
- Visit Union Square
- Moscone Convention Center
- Civic Center Plaza
- Louise Davies Symphony Hall
- Where to stay in San Francisco
- Van Ness Avenue
- Sf Camerawork
- Palace Hotel
- Bill Graham Civic Auditorium
- Crocker Galleria
- Yerba Buena Ice Skating Center
- Crocker Bank Building
- The Museum Store
- St. Mary Square
- Cable Car Museum
- The Regency Ballroom
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.