Downtown San Francisco Vacations from $906

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Your Downtown San Francisco Vacation

Experience everything Downtown San Francisco has to offer with a tailor-made Downtown San Francisco vacation package. From its history and shopping to its dining, prepare to be captivated by this busy neighborhood. When it's time to see the sights, you'll find plenty of big-name attractions nearby including Pier 39, Alcatraz Island and Lombard Street. Tick off one, two or all during your trip to Downtown San Francisco. Don't just think about it — turn it into reality! Book your ultimate Downtown San Francisco vacation with Expedia and experience travel your way.

The Latest Downtown San Francisco Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Hotel Riu Plaza Fisherman's Wharf
 The Huntington Hotel
MacArthur Place Hotel & Spa
The Grove Inn
Solage, Auberge Collection

Where to stay in Downtown San Francisco

Find the best Downtown San Francisco areas and neighborhoods for the activities you enjoy most. Learn more about Downtown San Francisco

Downtown San Francisco Hotel Deals

Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave San Francisco CA
Fully refundableReserve now, pay when you stay
$132 nightly
The price is $155 total per night from Apr 12 to Apr 13
$155 total
Apr 12 - Apr 13
Total with taxes and fees
9/10 Wonderful! (5,430 reviews)
I won't ever stay anywhere else in the city. I'm so glad I found my forever hotel. It's great!

Reviewed on Mar 21, 2026

Holiday Inn Golden Gateway by IHG
Handlery Union Square Hotel

Handlery Union Square Hotel

3.5 out of 5
351 Geary St San Francisco CA
Fully refundableReserve now, pay when you stay
$137 nightly
The price is $161 total per night from Apr 6 to Apr 7
$161 total
Apr 6 - Apr 7
Total with taxes and fees
8.8/10 Excellent! (2,922 reviews)
The staff was very helpful and patient with our needs. The room was nice.

Reviewed on Mar 21, 2026

Handlery Union Square Hotel
YOTEL San Francisco

YOTEL San Francisco

3 out of 5
1095 Market St San Francisco CA
Fully refundableReserve now, pay when you stay
$103 nightly
The price is $122 total per night from Mar 31 to Apr 1
$122 total
Mar 31 - Apr 1
Total with taxes and fees
8.2/10 Very Good! (1,009 reviews)
The room is tiny! But it worked. I was awoken by very loud music at 5am, unfortunately. Took a star off due to that, the slim selection at breakfast, one elevator being out of service, and the check-in kiosk not working for me.

Reviewed on Mar 21, 2026

YOTEL San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Downtown San Francisco

Things to do

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.