Downtown San Francisco Vacations from $280
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Your Downtown San Francisco Vacation
Experience everything Downtown San Francisco has to offer with a tailor-made Downtown San Francisco vacation package. From its history and shopping to its dining, prepare to be captivated by this busy neighborhood. When it's time to see the sights, you'll find plenty of big-name attractions nearby including Pier 39, Alcatraz Island and Lombard Street. Tick off one, two or all during your trip to Downtown San Francisco. Don't just think about it — turn it into reality! Book your ultimate Downtown San Francisco vacation with Expedia and experience travel your way.
The Latest Downtown San Francisco Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Beacon Grand, A Union Square Hotel
Union Square
Save 100% on your flight
Price was $988, price is now $630 per person
$630
per person
May 11 - May 15
found 1 day ago
Roundtrip non-stop flight included
Dallas (DFW) to San Francisco (SFO)
9.2/10 Wonderful! (1,920 reviews)
Our stay was absolutely amazing. They let us check in early our room was great! They put our family on same floor like requested honestly our experience here was exceptional! Thank you to the staff!
Reviewed on Mar 4, 2026
Aqua Breeze Inn
Westside Santa Cruz
Price was $773, price is now $496 per person
$496
per person
May 17 - May 22
found 1 hour ago
Roundtrip non-stop flight included
Seattle (SEA) to San Jose (SJC)
8/10 Very Good! (1,002 reviews)
For a budget friendly location. I can't complain. It was within walking distance of everything you need. And only steps from the boardwalk. The property is definitely a little older but the rooms were clean and adequate for what I paid. Although I may look for something different on our next stay. I would consider staying here again in the future.
Reviewed on Mar 7, 2026
Art House Hotel and Suites
Downtown Santa Rosa
Save 100% on your flight
Price was $808, price is now $531 per person
$531
per person
May 21 - May 24
found 1 day ago
Roundtrip flight included
Los Angeles (LAX) to San Francisco (SFO)
9.4/10 Exceptional! (575 reviews)
Location is great, rooms where very nice and clean and great air conditioning. Breakfast was sparse with no hot food and wrapped bagels/pastries. Just not my thing. Parking was bit expensive when could travel a block and pay $10 instead. Still loved it!
Reviewed on Mar 6, 2026
Where to stay in Downtown San Francisco
Find the best Downtown San Francisco areas and neighborhoods for the activities you enjoy most. Learn more about Downtown San Francisco
Union Square
4/5(5,164 area reviews)
Major tourist destination in downtown San Francisco, Union Square boasts shopping, hotels, and theaters. Explore department stores, boutiques, and galleries, or catch a performance at various theaters. Enjoy the Dewey Monument and stunning views from nearby hotels. Easily accessible via cable car lines, buses, and subway systems.
Downtown San Francisco Hotel Deals
Holiday Inn Golden Gateway by IHG
1500 Van Ness Ave San Francisco CA
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $159 total per night from Mar 29 to Mar 30
$159 total
Mar 29 - Mar 30
Total with taxes and fees
9/10 Wonderful! (5,373 reviews)
The gym has two stair bikes, two elliptical machines and three treadmills. One of the elliptical and one of the treadmills were out of service while I was there. They have screens with movies like you are riding on trails, which is a nice distraction. It has some dumbbells and a weight machine. It ...
Reviewed on Mar 7, 2026
Handlery Union Square Hotel
351 Geary St San Francisco CA
Fully refundableReserve now, pay when you stay
$149 nightly
The price is $176 total per night from Apr 1 to Apr 2
$176 total
Apr 1 - Apr 2
Total with taxes and fees
8.8/10 Excellent! (2,912 reviews)
The room was clean. The service was excellent. Our room was a little cold. We called guests service and a technician was sent to our room within minutes. We were offered a portable heater and that took care of the problem.
Reviewed on Mar 8, 2026
YOTEL San Francisco
1095 Market St San Francisco CA
Fully refundableReserve now, pay when you stay
$107 nightly
The price is $126 total per night from Mar 31 to Apr 1
$126 total
Mar 31 - Apr 1
Total with taxes and fees
8.2/10 Very Good! (1,022 reviews)
Room was tiny. Nice to have a towel warmer, but accessible from shower so towel got cold before it could be used.
Reviewed on Mar 6, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Downtown San Francisco
Oracle Park
Whether or not you’re a baseball fan, this charming ballpark with outstanding views should be on your San Francisco sightseeing list.
Moscone Convention Center
During your trip, find out what's happening at Moscone Convention Center, a top convention center in San Francisco. Discover the fascinating museums and shops in this vibrant area.
Chase Center
Catch an event at Chase Center during your trip to San Francisco. Amble around this vibrant area's Chinatown or experience its fascinating museums.
Things to do
Official Alcatraz Island Prison Tour with Free App Audio Packages
$86
per adult
100% of travellers recommend
California Academy of Sciences Daytime Admission
$49
per adult
86% of travellers recommend
Alcatraz Visit with Night Option and SF Bay Cruise
$139
per adult
94% of travellers recommend
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- San Francisco Vacations
- Grace Cathedral
- San Francisco Museum of Modern Art
- Warfield Theatre
- San Francisco City Hall
- Golden Gate Theatre
- Shn Curran Theatre
- Visit San Francisco
- American Conservatory Theater
- Luggage Store Gallery
- Westin St Francis Hotel Glass Elevators
- Union Square Vacations
- Lorraine Hansberry Theatre
- Embarcadero Center
- San Francisco Magic Parlor
- Maxwell Galleries
- Sf Playhouse
- Eleonore Austerer Gallery
- Maiden Lane
- United Nations Plaza
- San Francisco Federal Building
- Yerba Buena Gardens
- Xanadu Gallery
- 450 Sutter Building
- Orpheum Theatre
- Westfield Metreon
- Asian Art Museum of San Francisco
- Sf Masonic Auditorium
- Pacific-Union Club
- Great American Music Hall
- Lotta's Fountain
- Children's Creativity Museum
- Visit Union Square
- Moscone Convention Center
- Civic Center Plaza
- Louise Davies Symphony Hall
- Where to stay in San Francisco
- Van Ness Avenue
- Sf Camerawork
- Palace Hotel
- Bill Graham Civic Auditorium
- Crocker Galleria
- Yerba Buena Ice Skating Center
- Crocker Bank Building
- The Museum Store
- St. Mary Square
- Cable Car Museum
- The Regency Ballroom
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.