Downtown San Francisco Vacations from $375

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Your Downtown San Francisco Vacation

Experience everything Downtown San Francisco has to offer with a tailor-made Downtown San Francisco vacation package. From its history and shopping to its dining, prepare to be captivated by this busy neighborhood. When it's time to see the sights, you'll find plenty of big-name attractions nearby including Pier 39, Alcatraz Island and Lombard Street. Tick off one, two or all during your trip to Downtown San Francisco. Don't just think about it — turn it into reality! Book your ultimate Downtown San Francisco vacation with Expedia and experience travel your way.

The Latest Downtown San Francisco Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Fitzgerald Hotel

Fitzgerald Hotel

3 out of 5
Union Square
Save 100% on your flight
Price was $656, price is now $375 per person
$375
per person
Dec 25 - Dec 31
found 1 day ago
Roundtrip flight included
Burbank (BUR) to San Francisco (SFO)
15.6/10 Exceptional! (485 reviews)
I enjoyed my stay at The Fitzgerald. Its located at a very convenient area in Union Square and there are a wide variety of restaurants near by. Im aware this is an old building; however, the staff does a great job in cleaning, you can chose to have housekeeping every day. Had a mini fridge and a full bathroom (with tub), which was very convenient. There's also free continental breakfast from.7am to 10am.

Reviewed on Nov 24, 2025

San Carlos Inn

San Carlos Inn

2 out of 5
Price was $852, price is now $439 per person
$439
per person
Feb 5 - Feb 9
found 1 day ago
Roundtrip non-stop flight included
New York (NYC) to San Francisco (SFO)
14/10 Exceptional! (316 reviews)
room could have been cleaner fridge and micro wave were not spotless

Reviewed on Nov 21, 2025

Montage Healdsburg

Montage Healdsburg

5 out of 5
Price was $2,099, price is now $1,109 per person
$1,109
per person
Feb 12 - Feb 15
found 1 day ago
Roundtrip flight included
Burbank (BUR) to San Francisco (SFO)
19.2/10 Exceptional! (113 reviews)
Overall, the property was beautiful. However, we had an issue with black beetles in our restroom. I notified the front desk after killing three of them myself and all they did was spray a menthol cleaning agent around the tub. In the morning, I woke up to five or six of them under the bathmat. This ruined room as I am deadly terrified of bugs. At checkout, I did let them know about this and they comped my parking which I feel was an understatement considering what an inconvenience it was to smash black bugs all night. Sad to say that I was not very comfortable.

Reviewed on Nov 2, 2025

Bay Landing San Francisco Airport Hotel

Bay Landing San Francisco Airport Hotel

3 out of 5
Bayfront
Save 100% on your flight
Price was $784, price is now $428 per person
$428
per person
Dec 25 - Dec 31
found 1 day ago
Roundtrip flight included
Burbank (BUR) to San Francisco (SFO)
18/10 Exceptional! (4,699 reviews)
Great room for overnight.

Reviewed on Nov 25, 2025

Hotel Healdsburg

Hotel Healdsburg

4 out of 5
Save 100% on your flight
Price was $1,471, price is now $844 per person
$844
per person
Dec 26 - Dec 30
found 19 hours ago
Roundtrip flight included
Los Angeles (LAX) to San Francisco (SFO)
18.4/10 Exceptional! (427 reviews)
Nice Hotel close to everything. Valet took care of us everyday. Bartender could use a little help in customer service, was a little rude on a couple occasions. All in all great stay and a nice hotel

Reviewed on Nov 23, 2025

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Where to stay in Downtown San Francisco

Find the best Downtown San Francisco areas and neighborhoods for the activities you enjoy most. Learn more about Downtown San Francisco
Union Square which includes a high rise building and a city

Union Square

4/5(5,164 area reviews)

Major tourist destination in downtown San Francisco, Union Square boasts shopping, hotels, and theaters. Explore department stores, boutiques, and galleries, or catch a performance at various theaters. Enjoy the Dewey Monument and stunning views from nearby hotels. Easily accessible via cable car lines, buses, and subway systems.

Find hotels in Union Square

Downtown San Francisco Hotel Deals

Hilton San Francisco Financial District

Hilton San Francisco Financial District

4 out of 5
750 Kearny St San Francisco CA
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $119 total per night from Dec 14 to Dec 15
$119 total
Dec 14 - Dec 15
Total with taxes and fees
8.6/10 Excellent! (2,019 reviews)
Best ever thank you

Reviewed on Nov 17, 2025

Hilton San Francisco Financial District
Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave San Francisco CA
Fully refundableReserve now, pay when you stay
$112 nightly
The price is $132 total per night from Nov 30 to Dec 1
$132 total
Nov 30 - Dec 1
Total with taxes and fees
8.8/10 Excellent! (4,867 reviews)
There wasnt much in the direct vicinity of the hotel but great location for public transport and the hotel has wonderful views and modern clean rooms. I wish the lobby was upgraded but the staff was grear!

Reviewed on Nov 24, 2025

Holiday Inn Golden Gateway by IHG
Hyatt Regency San Francisco

Hyatt Regency San Francisco

4 out of 5
5 Embarcadero Center San Francisco CA
Fully refundableReserve now, pay when you stay
$183 nightly
The price is $215 total per night from Dec 14 to Dec 15
$215 total
Dec 14 - Dec 15
Total with taxes and fees
9.2/10 Wonderful! (1,972 reviews)
Room is excellent

Reviewed on Nov 20, 2025

Hyatt Regency San Francisco
See all 981 properties in Downtown San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Discover the most popular places to visit in Downtown San Francisco

Moscone Convention Center

Moscone Convention Center

4/5(598 reviews)

During your trip, find out what's happening at Moscone Convention Center, a top convention center in San Francisco. Discover the fascinating museums and shops in this vibrant area.

Moscone Convention Center
Oracle Park featuring a bay or harbor and street scenes as well as a small group of people

Oracle Park

4.5/5(1,454 reviews)

Whether or not you’re a baseball fan, this charming ballpark with outstanding views should be on your San Francisco sightseeing list.

Oracle Park
Embarcadero Plaza

Ferry Building

4.5/5(182 reviews)

During your trip to San Francisco, you can enjoy retail therapy at Ferry Building. Discover the acclaimed theater scene and notable monuments in this vibrant area.

Ferry Building

Things to do

California Academy of Sciences General Admission

California Academy of Sciences Daytime Admission

$49
per adult
84% of travellers recommend
California Academy of Sciences Daytime Admission
Alcatraz San Francisco Bay Cruise with Night Option

Alcatraz Visit with Night Option and SF Bay Cruise

$139
per adult
92% of travellers recommend
Alcatraz Visit with Night Option and SF Bay Cruise
San Francisco City Lights Cruise

San Francisco City Lights Cruise (2-hours)

$58
per adult
94% of travellers recommend
San Francisco City Lights Cruise (2-hours)
See all activities in San Francisco

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