Downtown San Francisco Vacations from $190
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Your Downtown San Francisco Vacation
Experience everything Downtown San Francisco has to offer with a tailor-made Downtown San Francisco vacation package. From its history and shopping to its dining, prepare to be captivated by this busy neighborhood. When it's time to see the sights, you'll find plenty of big-name attractions nearby including Pier 39, Alcatraz Island and Lombard Street. Tick off one, two or all during your trip to Downtown San Francisco. Don't just think about it — turn it into reality! Book your ultimate Downtown San Francisco vacation with Expedia and experience travel your way.
The Latest Downtown San Francisco Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Cathedral Hill Hotel
Downtown San Francisco
$190
per person
Dec 3 - Dec 7
found 1 day ago
Roundtrip flight included
Los Angeles (LAX) to San Francisco (SFO)
7.2/10 Good! (741 reviews)
Friendly staff, rooms are very nice and clean and the free parking is an absolute added bonus, parking always available. I recommend this establishment.
Reviewed on Oct 19, 2026
Aqua Breeze Inn
Westside Santa Cruz
$230
per person
Dec 4 - Dec 6
found 1 day ago
Roundtrip flight included
Los Angeles (LAX) to San Jose (SJC)
8.2/10 Very Good! (1,003 reviews)
Everything was great from check in to the end of the stay. Location is great, the room was clean and worked out perfect.
Reviewed on Oct 20, 2026
The Grove Inn
Western Addition
$258
per person
Dec 31 - Jan 2
found 1 day ago
Roundtrip flight included
Los Angeles (LAX) to San Francisco (SFO)
9.2/10 Wonderful! (741 reviews)
This is a great place to stay. Close to public transportation, 1 and a half blocks to a beautiful park, trader Joes and more. Aziza was helpful and professional.
Reviewed on Oct 18, 2026
Where to stay in Downtown San Francisco
Find the best Downtown San Francisco areas and neighborhoods for the activities you enjoy most. Learn more about Downtown San Francisco
Union Square
Major tourist destination in downtown San Francisco, Union Square boasts shopping, hotels, and theaters. Explore department stores, boutiques, and galleries, or catch a performance at various theaters. Enjoy the Dewey Monument and stunning views from nearby hotels. Easily accessible via cable car lines, buses, and subway systems.
Fisherman's Wharf
1 out of top 10 points of interest in this area
Discover Pier 39, Ghirardelli Square, and the San Francisco Maritime National Historical Park in this bustling tourist hotspot. Savor seafood at family-owned restaurants and explore the sea lion colony, while enjoying convenient cable car access.
South of Market
From baseball games to top-notch art exhibits, find endless entertainment in one of San Francisco’s fastest-growing neighborhoods.
Mission District
Visit this San Francisco neighborhood brimming with culture, history, a lively art scene, buzzing nightlife and some of the city’s best burritos.
Nob Hill
Luxury hotels, historic mansions, and Michelin-starred restaurants abound in this upscale area. Explore Union Square shopping district, Grace Cathedral, and the SF Masonic Auditorium for a taste of culture and history.
Downtown San Francisco Hotel Deals
Holiday Inn Golden Gateway by IHG
1500 Van Ness Ave San Francisco CA
Fully refundableReserve now, pay when you stay
$119 nightly
$140 total
Nov 22 - Nov 23
Total with taxes and fees
Hilton San Francisco Union Square
333 O'Farrell St. San Francisco CA
Fully refundableReserve now, pay when you stay
$151 nightly
$178 total
Nov 22 - Nov 23
Total with taxes and fees
8.6/10 Excellent! (1,829 reviews)
"Parking is expensive but it’s frisco"
Reviewed on Oct 23, 2026
FOUND Hotel Carlton, Nob Hill
1075 Sutter St San Francisco CA
Fully refundableReserve now, pay when you stay
$81 nightly
$95 total
Nov 23 - Nov 24
Total with taxes and fees
8.6/10 Excellent! (2,005 reviews)
"Staff was almost excellent, at arrival you are sent an email with your room code ours was 6-8 digits I cant remember but it is also the code to enter the hotel after hours. I was waiting for food delivery and my phone died the lady at the front desk watched me leave the lobby take my food from the ..."
Reviewed on Oct 22, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Stay near popular Downtown San Francisco attractions
Moscone Convention Center
8.2/10 (2,926 reviews)
During your trip, find out what's happening at Moscone Convention Center, a top convention center in San Francisco. Discover the acclaimed theater scene and notable monuments in this vibrant area.
Chase Center
8.8/10 (1,176 reviews)
Catch an event at Chase Center during your trip to San Francisco. Amble around this vibrant area's Chinatown or experience its fascinating museums.
Oracle Park
8.8/10 (7,978 reviews)
Whether or not you’re a baseball fan, this charming ballpark with outstanding views should be on your San Francisco sightseeing list.
San Francisco Museum of Modern Art
9.0/10 (2,422 reviews)
Displaying artworks from Frida Kahlo to Andy Warhol, this museum of modern and contemporary art is one of the largest of its kind in the United States.
Embarcadero Center
9.2/10 (94 reviews)
During your visit to San Francisco, you can browse for the perfect souvenirs at Embarcadero Center. Amble around this vibrant area's Chinatown or experience its acclaimed theater scene.
Union Square
8.6/10 (1,277 reviews)
You can search for that perfect souvenir at Union Square during your trip to San Francisco. Discover the top-notch restaurants and fascinating museums in this walkable area.
SF Masonic Auditorium
9.0/10 (22 reviews)
You can make plans for a show at SF Masonic Auditorium on your trip to San Francisco. Discover the acclaimed art scene and notable monuments in this vibrant area.
Ferry Building
9.0/10 (348 reviews)
During your trip to San Francisco, you can enjoy retail therapy at Ferry Building. Discover the fascinating museums and notable monuments in this vibrant area.
Things to do
Alcatraz Inside tour with Round trip ferry & Audio App Packages
$86
per adult
94% of travellers recommend
California Academy of Sciences Daytime Admission
$49
per adult
86% of travellers recommend
San Francisco, Aquarium of the Bay General Admission Ticket
$29
per adult
96% of travellers recommend
Explore a world of travel with Expedia
- Alamo Square
- Yerba Buena Ice Skating Center
- Golden Gate Theatre
- Commercial Street
- Tin How Temple
- De Young Museum
- Shn Curran Theatre
- Greek Theater
- Coit Tower
- Sf Masonic Auditorium
- Bill Graham Civic Auditorium
- Japanese Tea Garden
- National Shrine of Saint Francis of Assisi
- Jack Kerouac Alley
- Union Square Ice Rink
- Civic Center Plaza
- Crocker Bank Building
- Dragon's Gate
- San Francisco Federal Building
- Conservatory of Flowers
- 555 California Street
- Van Ness Avenue
- San Francisco Mint
- Ghirardelli Chocolate Experience
- Civic Center Vacations
- Aquarium of the Bay
- American Conservatory Theater
- Saints Peter and Paul Church
- Uss Pampanito
- Chinese Historical Society of America
- San Francisco Zoo
- The Regency Ballroom
- Yerba Buena Gardens
- Lombard Street
- Grace Cathedral
- Telephone Pioneers Communication Museum
- Golden Gate Bridge
- Old St. Mary's Cathedral
- San Francisco Museum of Modern Art
- Alcatraz Island
- Kong Chow Temple
- Museum of Craft and Folk Art
- Cable Car Museum
- Balmy Alley
- Crocker Galleria
- San Francisco Vacations
- Sf Playhouse
- Musée Mécanique
- Children's Creativity Museum
- Columbus Tower
- Palace Hotel
- Oracle Park
- Walter S. Johnson Park
- Chase Center
- Moscone Convention Center
- San Francisco Maritime National Historical Park
- Palace of Fine Arts
- Maxwell Galleries
- Sf Armory
- Westfield San Francisco Centre
- Academy of Art University
- Mission San Francisco de Asís
- 450 Sutter Building
- Transamerica Redwood Forest
- Orpheum Theatre
- One Montgomery Terrace
- Muir Woods National Monument
- Chinatown Vacations
- Yerba Buena Center for the Arts
- Full House House
- Eleonore Austerer Gallery
- Transamerica Pyramid
- Ferry Building
- Crissy Field
- San Francisco City Hall
- Mrs. Doubtfire House
- Fisherman's Wharf Vacations
- St. Mary Square
- Union Square
- Union Square Vacations
- Wells Fargo History Museum
- United Nations Plaza
- Warfield Theatre
- Magowan's Infinite Mirror Maze
- Asian Art Museum of San Francisco
- Maiden Lane
- Pier 39
- Marines Memorial Theater
- The Cannery at Del Monte Square
- Lotta's Fountain
- Baker Beach
- Pacific-Union Club
- California Academy of Sciences
- Embarcadero Center
- Ripley's Believe It Or Not Museum
- Walt Disney Family Museum
- Ghirardelli Square
- St. Patrick Catholic Church
- Westin St Francis Hotel Glass Elevators
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.