Downtown San Francisco Vacations from $543

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Your Downtown San Francisco Vacation

Experience everything Downtown San Francisco has to offer with a tailor-made Downtown San Francisco vacation package. From its history and shopping to its dining, prepare to be captivated by this busy neighborhood. When it's time to see the sights, you'll find plenty of big-name attractions nearby including Pier 39, Alcatraz Island and Lombard Street. Tick off one, two or all during your trip to Downtown San Francisco. Don't just think about it — turn it into reality! Book your ultimate Downtown San Francisco vacation with Expedia and experience travel your way.

The Latest Downtown San Francisco Vacation Packages

Price found within the past 48 hours. Click for updated prices.
San Francisco Proper Hotel

San Francisco Proper Hotel

4 out of 5
Downtown San Francisco
Save 100% on your flight
Price was $1,021, price is now $543 per person
$543
per person
Jan 15 - Jan 20
found 1 day ago
Roundtrip flight included
Burbank (BUR) to San Francisco (SFO)
8.8/10 Excellent! (789 reviews)
Despite the surround area, the hotel itself is very welcoming and everyone very friendly and above and beyond to make you feel welcome. Rooms were clean and good amenities. I didn’t have a reservation for the rooftop but the team squeezed me in - great views and cocktails!

Reviewed on Nov 23, 2025

The Phoenix Hotel

The Phoenix Hotel

3 out of 5
Downtown San Francisco
Price was $1,125, price is now $567 per person
$567
per person
Jan 6 - Jan 13
found 1 day ago
Roundtrip flight included
Burbank (BUR) to San Francisco (SFO)
9/10 Wonderful! (1,004 reviews)
Excellent customer service, aesthetic fantastic, beautiful details, one of a kind. You have to stay here at least once! Culturally iconic.

Reviewed on Nov 30, 2025

Montage Healdsburg

Montage Healdsburg

5 out of 5
Price was $2,060, price is now $1,086 per person
$1,086
per person
Feb 12 - Feb 15
found 1 day ago
Roundtrip flight included
Burbank (BUR) to San Francisco (SFO)
9.6/10 Exceptional! (113 reviews)
Clean room, kind and helpful staff. Nice ambiance in vineyard.

Reviewed on Nov 30, 2025

Hotel Healdsburg

Hotel Healdsburg

4 out of 5
Save 100% on your flight
Price was $1,419, price is now $787 per person
$787
per person
Jan 8 - Jan 12
found 6 hours ago
Roundtrip flight included
Seattle (SEA) to San Francisco (SFO)
9.2/10 Wonderful! (427 reviews)
Nice Hotel close to everything. Valet took care of us everyday. Bartender could use a little help in customer service, was a little rude on a couple occasions. All in all great stay and a nice hotel

Reviewed on Nov 23, 2025

H2Hotel

H2Hotel

4 out of 5
Save 100% on your flight
Price was $1,085, price is now $612 per person
$612
per person
Jan 8 - Jan 12
found 6 hours ago
Roundtrip flight included
Seattle (SEA) to San Francisco (SFO)
9.4/10 Exceptional! (697 reviews)
The room was beautiful and so clean. Loved the location

Reviewed on Dec 1, 2025

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Where to stay in Downtown San Francisco

Find the best Downtown San Francisco areas and neighborhoods for the activities you enjoy most. Learn more about Downtown San Francisco
Union Square which includes a high rise building and a city

Union Square

4/5(5,164 area reviews)

Major tourist destination in downtown San Francisco, Union Square boasts shopping, hotels, and theaters. Explore department stores, boutiques, and galleries, or catch a performance at various theaters. Enjoy the Dewey Monument and stunning views from nearby hotels. Easily accessible via cable car lines, buses, and subway systems.

Find hotels in Union Square

Downtown San Francisco Hotel Deals

Hilton San Francisco Financial District

Hilton San Francisco Financial District

4 out of 5
750 Kearny St San Francisco CA
Fully refundableReserve now, pay when you stay
$89 nightly
The price is $105 total per night from Dec 14 to Dec 15
$105 total
Dec 14 - Dec 15
Total with taxes and fees
8.6/10 Excellent! (2,071 reviews)
Great room, great view and great staff...ridiculous parking fees!!

Reviewed on Dec 1, 2025

Hilton San Francisco Financial District
Holiday Inn Golden Gateway by IHG

Holiday Inn Golden Gateway by IHG

3.5 out of 5
1500 Van Ness Ave San Francisco CA
Fully refundableReserve now, pay when you stay
$112 nightly
The price is $132 total per night from Dec 14 to Dec 15
$132 total
Dec 14 - Dec 15
Total with taxes and fees
8.8/10 Excellent! (4,890 reviews)
Staff was pleasant and helpful. Room was clean. Bed was comfortable. I enjoyed my stay.

Reviewed on Nov 30, 2025

Holiday Inn Golden Gateway by IHG
Fairmont San Francisco

Fairmont San Francisco

5 out of 5
950 Mason Street Atop Nob Hill San Francisco CA
Fully refundableReserve now, pay when you stay
$210 nightly
The price is $247 total per night from Dec 14 to Dec 15
$247 total
Dec 14 - Dec 15
Total with taxes and fees
9/10 Wonderful! (1,437 reviews)
No body wash in the shower

Reviewed on Nov 28, 2025

Fairmont San Francisco
See all 986 properties in Downtown San Francisco
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
All Inclusive Vacations
All Inclusive Vacations
Beach Vacations
Beach Vacations
Kid Friendly Vacations
Kid Friendly Vacations

Discover the most popular places to visit in Downtown San Francisco

Moscone Convention Center

Moscone Convention Center

4/5(598 reviews)

During your trip, find out what's happening at Moscone Convention Center, a top convention center in San Francisco. Discover the fascinating museums and shops in this vibrant area.

Moscone Convention Center
Oracle Park featuring a bay or harbor and street scenes as well as a small group of people

Oracle Park

4.5/5(1,454 reviews)

Whether or not you’re a baseball fan, this charming ballpark with outstanding views should be on your San Francisco sightseeing list.

Oracle Park
Embarcadero Plaza

Ferry Building

4.5/5(182 reviews)

During your trip to San Francisco, you can enjoy retail therapy at Ferry Building. Discover the acclaimed theater scene and notable monuments in this vibrant area.

Ferry Building

Things to do

California Academy of Sciences General Admission

California Academy of Sciences Daytime Admission

$49
per adult
84% of travellers recommend
California Academy of Sciences Daytime Admission
San Francisco City Lights Cruise

San Francisco City Lights Cruise (2-hours)

$58
per adult
94% of travellers recommend
San Francisco City Lights Cruise (2-hours)
Bridge 2 Bridge Tour: Golden Gate Bridge to Bay Bridge

San Francisco Bridge to Bridge Cruise (90-minutes)

$48
per adult
92% of travellers recommend
San Francisco Bridge to Bridge Cruise (90-minutes)
See all activities in San Francisco

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.