Beginning of main content
Trip Type
Flight 1
Flight 2
Flight 3
Flight 4
Flight 5

Search 321,000 hotels worldwide.

Get the price guarantee available for your trip.

No Expedia cancellation fee to change or cancel almost any hotel reservation.


Featured Texas Medical Center Extended Stay America Hotels

See all 567 Hotels in Texas Medical Center
Extended Stay America Houston - Galleria - Westheimer

Extended Stay America Houston - Galleria - Westheimer

4701 Westheimer Rd, Houston
2.5 out of 5.0
3.0 out of 5 (132 reviews)
Close to down town Room cleanliness needs improving. The bath tub leaked. - 

$76

$76
Extended Stay America Houston - Westchase - Richmond

Extended Stay America Houston - Westchase - Richmond

3200 W Sam Houston Pkwy S, Houston
2.5 out of 5.0
2.7 out of 5 (43 reviews)
Nice for an expensive hotel. Close to shop and stores. Public transit is available if you need if. Not bad. Pretty quiet when I … - 

$67

$67
Extended Stay America Houston - Greenspoint

Extended Stay America Houston - Greenspoint

13505 North Fwy, Houston
2.5 out of 5.0
3.0 out of 5 (30 reviews)
Good location with easy freeway access They were very accommodating during a natural disaster. - 

$85

$85
Extended Stay America Houston - Galleria - Uptown

Extended Stay America Houston - Galleria - Uptown

2300 West Loop S, Houston
2.5 out of 5.0
2.9 out of 5 (158 reviews)
Business stay at ESA As usual I found everything clean and prepared for me upon arrival. Bed was comfortable television … - 

$81

$81
Extended Stay America - Houston - Greenway Plaza

Extended Stay America - Houston - Greenway Plaza

2330 Southwest Fwy, Houston
2.5 out of 5.0
3.3 out of 5 (120 reviews)
Staff is very friendly and super helpful. Not a easy time during the storm but we had a blessed sta … - 

$85

$85
Extended Stay America - Houston - Katy Frwy -Energy Corridor

Extended Stay America - Houston - Katy Frwy -Energy Corridor

15385 Katy Freeway, Houston
2.5 out of 5.0
2.3 out of 5 (109 reviews)
Receptionist was condescending when I asked for a quiet area of the hotel. There was a dog or two i … - 

$75

$75
Extended Stay America - Houston - Sugar Land

Extended Stay America - Houston - Sugar Land

13420 Southwest Freeway, Sugar Land
2.5 out of 5.0
2.7 out of 5 (79 reviews)
Nice hotel close to Hwy 59 South My family and I enjoyed our stay while my husband was out in the area for work. We will definitely … - 

$70

$70
Extended Stay America -Houston-Med Ctr-NRG Pk-Braeswood Blvd

Extended Stay America -Houston-Med Ctr-NRG Pk-Braeswood Blvd

1301 Braeswood Blvd, Houston
2.5 out of 5.0
3.0 out of 5 (163 reviews)
Nice hotel Nice hotel with nice size rooms. Will stay again and recommend to friends. - 

$99

$99
Extended Stay America - Houston - Med Ctr-NRG Park-Fannin

Extended Stay America - Houston - Med Ctr-NRG Park-Fannin

7979 Fannin St, Houston
2.5 out of 5.0
2.8 out of 5 (274 reviews)
Close to VA hospital is the ONLY reason I stay Stay 1-2 times a month. Management is sloppy, housekeeping is very slipshod. Over last 5 stays: 1. … - 

$85

$85
Extended Stay America Houston - Willowbrook - HWY 249

Extended Stay America Houston - Willowbrook - HWY 249

16939 Tomball Pkwy, Houston
2.5 out of 5.0
3.5 out of 5 (36 reviews)
Great experience Victor at the front desk was very friendly and kind. My room was on the first floor near the front … - 

$94

$94
Extended Stay America Houston - Westchase - Westheimer

Extended Stay America Houston - Westchase - Westheimer

2424 W Sam Houston Pkwy S, Houston
2.5 out of 5.0
3.1 out of 5 (34 reviews)
Convenient Front desk personnel was awesome. They were ready for me to check in and were willing to help in an … - 

$85

$85
Extended Stay America, Houston, Northwest HWY 290, Hollister

Extended Stay America, Houston, Northwest HWY 290, Hollister

5454 Hollister St, Houston
2.5 out of 5.0
2.9 out of 5 (22 reviews)
Good in a pinch, if you're not picky Had to make an emergency trip to Houston, and wanted to keep it under $100 for lodging. This was th … - 

$81

$81
Extended Stay America - Houston - Med Ctr - NRG Park - Kirby

Extended Stay America - Houston - Med Ctr - NRG Park - Kirby

1303 La Concha Ln, Houston
2.5 out of 5.0
3.0 out of 5 (57 reviews)
Booked this hotel because it was close to NRG stadium. Paid for a queen bed but got a full instead. … - 

$112

$112
Extended Stay America Houston - Stafford

Extended Stay America Houston - Stafford

4726 Sugar Grove Blvd, Stafford
2.5 out of 5.0
3.0 out of 5 (43 reviews)
Very clean room and great location, granddaughter loved the pool. - 

$67

$67
Extended Stay America - Houston - I-10 West - CityCentre

Extended Stay America - Houston - I-10 West - CityCentre

11175 Katy Fwy, Houston
2.5 out of 5.0
3.1 out of 5 (46 reviews)
GREAT PROPERTY, LOCATION AND PERSONNEL MATT,TAHA, DANIELLE, ELIZABETH, NANCY ALL OF THE STAFF ARE EXCEPTIONAL. - 

$67

$67
Map

Recently booked Texas Medical Center hotels

Crowne Plaza Hotel Houston near Reliant - Medical
3.5 out of 5.0
Last booking: 22 minutes ago
Holiday Inn Express & Suites Houston Medical Center
2.5 out of 5.0
Last booking: 46 minutes ago
Motel 6 Houston NRG Park - Reliant Stadium
2.0 out of 5.0
Last booking: 51 minutes ago
8080 Main
2.5 out of 5.0
Last booking: 1 hour ago
Wyndham Houston - Medical Center Hotel and Suites
3.5 out of 5.0
Last booking: 1 hour ago
Hilton Houston Plaza / Medical Center
3.5 out of 5.0
Last booking: 1 hour ago
Courtyard by Marriott Houston Medical Center
3.0 out of 5.0
Last booking: 1 hour ago
Extended Stay America - Houston - Med Ctr-NRG Park-Fannin
2.5 out of 5.0
Last booking: 4 hours ago
Houston Marriott Medical Center
4.0 out of 5.0
Last booking: 6 hours ago

Pocket Guide: Extended Stay America Hotels in Texas Medical Center

Search for hotels in Texas Medical Center on Expedia. You can easily find your hotels in Texas Medical Center using one of the methods below:

  • View our selection of featured hotels in Texas Medical Center
  • Use the map to find hotels in the Texas Medical Center neighborhood you prefer
  • Use the filters to see hotels in a specific area of Texas Medical Center, select a specific theme, brand, or hotel class from basic (1 Star) to luxury hotels (5 Stars) in Texas Medical Center
  • Enter your travel dates to view the best deals on hotels in Texas Medical Center - while they last