Texas Medical Center Vacations from $227
Book a Hotel + Flight or Car together to unlock savings
Your Texas Medical Center Vacation
Texas Medical Center is calling! Whatever type of break you're organizing, you can see and experience the best of this neighborhood with a Texas Medical Center vacation package. Your trip to Texas Medical Center wouldn't be complete without a stop at top attractions nearby such as Houston Zoo, Houston Natural Science Museum and Childrens Museum of Houston. Whatever your travel plans or the size of your budget, booking a perfect Texas Medical Center vacation is quick and easy with Expedia.
The Latest Texas Medical Center Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Heritage Place Houston Brookhollow
Lazybrook/Timbergrove
Save 100% on your flight
Price was $367, price is now $227 per person
$227
per person
Nov 6 - Nov 11
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Houston (IAH)
8.4/10 Very Good! (419 reviews)
Staff was exceptional, great place to lay your head, hidden gem!
Reviewed on Sep 29, 2025
Hilton Houston North
Northside
Save 100% on your flight
Price was $655, price is now $352 per person
$352
per person
Dec 9 - Dec 15
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Houston (IAH)
8.2/10 Very Good! (1,010 reviews)
Staff was amazing!!!!! BUT, we were missing a tv remote, the elevators weren’t working, and that part of town seemed really unsafe.
Reviewed on Oct 5, 2025
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Greater Uptown
Save 100% on your flight
Price was $593, price is now $346 per person
$346
per person
Nov 6 - Nov 11
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Houston (IAH)
8.2/10 Very Good! (2,530 reviews)
Room need an upgrade urgently.
Reviewed on Oct 5, 2025
Hotel Saint Augustine
Montrose
Save 100% on your flight
Price was $778, price is now $465 per person
$465
per person
Dec 11 - Dec 14
found 1 day ago
Roundtrip flight included
Chicago (ORD) to Houston (IAH)
9.8/10 Exceptional! (32 reviews)
Firstly, the staff was fantastic! Starting with the valet Jessie, the front desk staff, Sarah the bartender and Andrew the maitre d, all were extremely friendly and enthusiastic! The property was beautiful and comfortable and would highly recommend to anyone. Can’t wait to go back!
Reviewed on Sep 22, 2025
Where to stay in Texas Medical Center
Find the best Texas Medical Center areas and neighborhoods for the activities you enjoy most. Learn more about Texas Medical Center
Downtown Houston
3 out of top 10 points of interest in this area
4.5/5(2,300 area reviews)
Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.
Texas Medical Center Hotel Deals
Hilton Houston Plaza/Medical Center
6633 Travis St, Houston, TX
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $129 total per night from Oct 12 to Oct 13
$129 total
Oct 12 - Oct 13
Total with taxes and fees
8.2/10 Very Good! (1,603 reviews)
"Beautiful place. The staff was very helpful."
Reviewed on Sep 30, 2025
Blossom Hotel Houston
7118 Bertner Ave, Houston, TX
Fully refundableReserve now, pay when you stay
$161 nightly
The price is $188 total per night from Oct 12 to Oct 13
$188 total
Oct 12 - Oct 13
Total with taxes and fees
9/10 Wonderful! (3,541 reviews)
"Amazing stay Clean, updated and quiet"
Reviewed on Oct 3, 2025
Hyatt Place Houston Medical Center
7329 FANNIN STREET Building 2, Houston, TX
Fully refundableReserve now, pay when you stay
$140 nightly
The price is $163 total per night from Oct 9 to Oct 10
$163 total
Oct 9 - Oct 10
Total with taxes and fees
9/10 Wonderful! (2,001 reviews)
"Nice hotel. No issues"
Reviewed on Sep 27, 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Texas Medical Center
MD Anderson Cancer Center
Though MD Anderson Cancer Center might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here.
Texas Children's Hospital
Though Texas Children's Hospital might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here.
Harris Health System - Ben Taub General Hospital
Though Harris Health System - Ben Taub General Hospital might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here.
Things to do
Houston: Houston Botanic Garden Entry Ticket
$12
per adult
80% of travellers recommend
Houston Museum of Natural Science: Cockrell Butterfly Center
$15
per adult
100% of travellers recommend
Houston Museum of Natural Science General Admission Ticket
$25
per adult
96% of travellers recommend
Explore a world of travel with Expedia
Explore a world of travel with Expedia
- Houston Hotels
- Hotels near MD Anderson Cancer Center
- Hotels near Downtown Houston
- Hotels near NRG Stadium
- Cheap Hotels in Houston
- Hotels near TMC Transit Center
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- Apartments in Dryden/TMC Station
- Hotels near Dryden/TMC Station
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- Hotels near Smith Lands Station
- Hotels near Houston Zoo
- Hotels near Astrodome
- Apartments in Memorial Hermann Hospital/Houston Zoo Station
- Vacation Homes in Memorial Hermann Hospital/Houston Zoo Station
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- Hotels near Reckling Park
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- Hotels near Miller Outdoor Theater
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- Apartments in Stadium Park/Astrodome Station
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- Houston Zoo
- MD Anderson Cancer Center
- Hermann Park
- Rice University
- Reckling Park
- Houston Vacations
- Rice Stadium
- Miller Outdoor Theater
- NRG Stadium
- Visit Astrodome
- James Turrell's Twilight Epiphany Skyscape
- Houston Natural Science Museum
- Houston Museum of Fine Arts
- NRG Park
- Houston Museum District Vacations
- Children's Museum of Houston
- Holocaust Museum Houston
- Cullen Sculpture Garden
- Visit Riverside Terrace
- Buffalo Soldiers National Museum
- Visit Houston Museum District
- Car rentals near Houston
- Car rentals near MD Anderson Cancer Center
- Standard Car Rentals near MD Anderson Cancer Center
- Car rentals near Houston Zoo
- Sportscar Car Rentals near Houston Zoo
- Car rentals near Hermann Park
- Car rentals near Rice University
- Pickup Car Rentals near Rice University
- SUV Car Rentals near Rice University
- Van Car Rentals near Rice University
- Car rentals near James Turrell's Twilight Epiphany Skyscape
- Car rentals near Houston Museum District
- Thrifty Car Rental Rental Cars in Houston Museum District
- Hertz Rental Cars in Houston Museum District
- Alamo Rent A Car Rental Cars in Houston Museum District
- Pickup Car Rentals in Houston Museum District
- Sixt Rental Cars in Houston Museum District
- Discount Quebec Rental Cars in Houston Museum District
- Budget Rental Cars in Houston Museum District
- Enterprise Rental Cars in Houston Museum District
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.