Texas Medical Center Vacations

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Your Texas Medical Center Vacation

Texas Medical Center is calling! Whatever type of break you're organizing, you can see and experience the best of this neighborhood with a Texas Medical Center vacation package. Your trip to Texas Medical Center wouldn't be complete without a stop at top attractions nearby such as Houston Zoo, Houston Natural Science Museum and Childrens Museum of Houston. Whatever your travel plans or the size of your budget, booking a perfect Texas Medical Center vacation is quick and easy with Expedia.

Price found within the past 48 hours. Click for updated prices.
  • Aug 13 - Aug 16

    Kompose Residences Houston Cy-Fair + Flight

    Houston
    3 nights
    3.0 star property
    9.4/10 - Exceptional (582 reviews)
    "Clean room, Good breakfas"
    Reviewed June 4, 2026
    Roundtrip Atlanta (ATL) - Houston (IAH)
    ATL - IAHNonstop IAH - ATLNonstop
    $396
    $294
    per traveler
    found 2 days ago
    Kompose Residences Houston Cy-Fair
  • Aug 13 - Aug 16

    Experience a First Class Stay - 2 BDRM + Flight

    Humble
    3 nights
    3.5 star property
    8.0/10 - Very Good (5 reviews)
    "This people have water that smells like poop. Sewage water is what they use for water. Remnants of trash, sticky nastiness in drawers, air vents falling off ceilings. Random kids belts found? Candy stuck to floor? Trash wasn’t even taken out. Mind you I have kids that found these things as well. Oh and don’t even try and ask for them to refund you for their disgusting rental. They will give you the run around and then IGNORE YOU. Awful establishment and these people NEED TO BE SHUTDOWN."
    Reviewed March 11, 2022
    Roundtrip Atlanta (ATL) - Houston (IAH)
    ATL - IAHNonstop IAH - ATLNonstop
    Save 100% on your flight
    $686
    $452
    per traveler
    found 2 days ago
    Experience a First Class Stay - 2 BDRM
  • Aug 13 - Aug 16

    Luxury 3BR for Families Nurses and Group + Flight

    Northside
    3 nights
    2.0 star property
    Roundtrip Atlanta (ATL) - Houston (IAH)
    ATL - IAHNonstop IAH - ATLNonstop
    Save 100% on your flight
    $706
    $473
    per traveler
    found 2 days ago
    Luxury 3BR for Families Nurses and Group
  • Jul 8 - Jul 13

    TUSCAN VILLA + Flight

    Greater Uptown
    5 nights
    5.0 star property
    2.0/10 - (3 reviews)
    Roundtrip Atlanta (ATL) - Houston (IAH)
    ATL - IAHNonstop IAH - ATLNonstop
    Save 100% on your flight
    $4,006
    $2,866
    per traveler
    found 1 day ago
    TUSCAN VILLA
  • Jul 30 - Aug 2

    Holiday Inn Club Vacations Galveston Seaside Resort by IHG + Flight

    West End
    3 nights
    3.0 star property
    8.8/10 - Excellent (838 reviews)
    "We enjoyed our stay. However, there are a few “tips” for future travelers. The website is misleading. Only “Signature” guests have beachfront access; the majority have to cross a busy road and go under the “Signature “ building to get to the beach. You can use beach chairs free of charge by going to the first floor at Signature. We weren’t aware of this & happened upon it by pure luck! The bugs are horrendous. Do NOT walk on the grass or you will be attacked by some black bugs. Request a..."
    Reviewed June 2, 2026
    Roundtrip Atlanta (ATL) - Houston (IAH)
    ATL - IAHNonstop IAH - ATLNonstop
    Save 100% on your flight
    $708
    $522
    per traveler
    found 20 hours ago
    Holiday Inn Club Vacations Galveston Seaside Resort by IHG

Where to stay in Texas Medical Center

Find the best Texas Medical Center areas and neighborhoods for the activities you enjoy most. Learn more about Texas Medical Center

Texas Medical Center Hotel Deals

Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton

4 out of 5
7118 Bertner Ave Houston TX
Fully refundableReserve now, pay when you stay
$137 nightly
The price is $160 total per night from Jul 5 to Jul 6
$160 total
Jul 5 - Jul 6
Total with taxes and fees
9/10 Wonderful! (3,853 reviews)
"Amazing staff - and amenities super nice!"

Reviewed on Jun 2, 2026

Blossom Hotel Houston, Curio Collection by Hilton
Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

4.5 out of 5
6633 Travis St Houston TX
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $158 total per night from Jul 5 to Jul 6
$158 total
Jul 5 - Jul 6
Total with taxes and fees
8.4/10 Very Good! (1,948 reviews)
"Clean, quite and spacious."

Reviewed on Jun 1, 2026

Hilton Houston Plaza/Medical Center
Hyatt Place Houston Medical Center

Hyatt Place Houston Medical Center

3 out of 5
7329 FANNIN STREET Building 2 Houston TX
$128 nightly
The price is $149 total per night from Jun 11 to Jun 12
$149 total
Jun 11 - Jun 12
Total with taxes and fees
9.2/10 Wonderful! (2,513 reviews)
"Very nice and convenient place near the Medical district. Good breakfast buffet."

Reviewed on Jun 4, 2026

Hyatt Place Houston Medical Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.