Texas Medical Center Vacations
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Your Texas Medical Center Vacation
Texas Medical Center is calling! Whatever type of break you're organizing, you can see and experience the best of this neighborhood with a Texas Medical Center vacation package. Your trip to Texas Medical Center wouldn't be complete without a stop at top attractions nearby such as Houston Zoo, Houston Natural Science Museum and Childrens Museum of Houston. Whatever your travel plans or the size of your budget, booking a perfect Texas Medical Center vacation is quick and easy with Expedia.
The Latest Texas Medical Center Vacation Packages
Price found within the past 48 hours. Click for updated prices.
- Experience a First Class Stay - 2 BDRM
Jul 14 - Jul 16Experience a First Class Stay - 2 BDRM + Flight
Humble2 nights8.0/10 - Very Good (5 reviews)"This people have water that smells like poop. Sewage water is what they use for water. Remnants of trash, sticky nastiness in drawers, air vents falling off ceilings. Random kids belts found? Candy stuck to floor? Trash wasn’t even taken out. Mind you I have kids that found these things as well. Oh and don’t even try and ask for them to refund you for their disgusting rental. They will give you the run around and then IGNORE YOU. Awful establishment and these people NEED TO BE SHUTDOWN."Reviewed March 11, 2022Roundtrip • Atlanta (ATL) - Houston (IAH)ATL - IAH • Nonstop IAH - ATL • Nonstop - Hilton Houston North
Aug 5 - Aug 9Hilton Houston North + Flight
Northside4 nights8.4/10 - Very Good (1,007 reviews)"Ok"Reviewed June 10, 2026Roundtrip • Atlanta (ATL) - Houston (IAH)ATL - IAH • Nonstop IAH - ATL • Nonstop - The Moran CITYCENTRE
Aug 5 - Aug 9The Moran CITYCENTRE + Flight
Memorial4 nights9.0/10 - Wonderful (1,052 reviews)"Everything was perfect! Location, rooms, amenities and price!"Reviewed June 9, 2026Roundtrip • Atlanta (ATL) - Houston (IAH)ATL - IAH • Nonstop IAH - ATL • Nonstop - La Colombe d'Or Hotel
Aug 11 - Aug 16La Colombe d'Or Hotel + Flight
Montrose5 nights9.4/10 - Exceptional (189 reviews)"I could not have been more pleased with my stay! I have already booked 2 more stays at this lovely hotel. The staff was phenomenal. Friendly, helpful, and kind. I was in Houston for care at MD Anderson Cancer Hospital and the staff made every effort to keep me comfortable and make every second perfect for me. The food is spectacular and the pool is wonderful. I cannot wait to go back!!"Reviewed June 6, 2026Roundtrip • New York (LGA) - Houston (HOU)LGA - HOU • Nonstop IAH - JFK • Nonstop - The Royal Sonesta Houston Galleria
Aug 5 - Aug 9The Royal Sonesta Houston Galleria + Flight
The Galleria4 nights8.6/10 - Excellent (1,999 reviews)"Spend a week with daughter staying here, 12min walking from my room to the Galleria."Reviewed June 9, 2026Roundtrip • Atlanta (ATL) - Houston (IAH)ATL - IAH • Nonstop IAH - ATL • Nonstop
Where to stay in Texas Medical Center
Find the best Texas Medical Center areas and neighborhoods for the activities you enjoy most. Learn more about Texas Medical Center
Downtown Houston
4 out of top 10 points of interest in this area
4.5/5(2,329 area reviews)
Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.
Texas Medical Center Hotel Deals
Blossom Hotel Houston, Curio Collection by Hilton
7118 Bertner Ave Houston TX
Fully refundableReserve now, pay when you stay
$161 nightly
The price is $188 total per night from Jul 5 to Jul 6
$188 total
Jul 5 - Jul 6
Total with taxes and fees
9/10 Wonderful! (3,885 reviews)
"Beautiful property. Wonderful staff. A private shuttle will carry you anywhere you need to go within three miles of the hotel. You can request to be dropped off at a certain entrance for MD Anderson. I would stay here again. The week days are most enjoyable here."
Reviewed on Jun 10, 2026
Hilton Houston Plaza/Medical Center
6633 Travis St Houston TX
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $117 total per night from Jul 5 to Jul 6
$117 total
Jul 5 - Jul 6
Total with taxes and fees
8.4/10 Very Good! (1,962 reviews)
"It was close to everything. Perfect hub for checking out apartments throughout Houston for my son who’s moving there. The staff was great, especially Francisco the bartender in the restaurant! We were also able to get early check in & late checkout. Enjoyed the pool briefly. Definitely would stay ..."
Reviewed on Jun 9, 2026
Hyatt Place Houston Medical Center
7329 FANNIN STREET Building 2 Houston TX
$127 nightly
The price is $149 total per night from Jul 5 to Jul 6
$149 total
Jul 5 - Jul 6
Total with taxes and fees
9.2/10 Wonderful! (2,536 reviews)
"Easy check-in and nice accommodations"
Reviewed on Jun 9, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Texas Medical Center
NRG Stadium
4.5/5(634 reviews)
Catch an event at NRG Stadium during your trip to Houston. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
Space Center Houston
4.5/5(1,093 reviews)
This iconic “mission control” was immortalized for its role in the first moon landing.
Daikin Park
4.5/5(915 reviews)
Catch an event at Daikin Park during your trip to Houston. Experience the acclaimed theater scene and great live music in this vibrant area.
Things to do
Space Center Houston Admission Ticket
$33
per adult
92% of travellers recommend
Houston: Space Center Houston Admission Ticket
$30
per adult
92% of travellers recommend
NASA's Space Center & Official Houston City Tour with tickets
$109
per adult
92% of travellers recommend
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- Houston Hotels
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- Houston Zoo
- Md Anderson Cancer Center
- Hermann Park
- Rice University
- Reckling Park
- Houston Vacations
- Rice Stadium
- Miller Outdoor Theater
- Nrg Stadium
- Visit Astrodome
- James Turrell's Twilight Epiphany Skyscape
- Houston Natural Science Museum
- Houston Museum of Fine Arts
- Nrg Park
- Museum District Vacations
- Children's Museum of Houston
- Holocaust Museum Houston
- Cullen Sculpture Garden
- Visit Riverside Terrace
- Buffalo Soldiers National Museum
- Visit Museum District
- Car rentals near Houston
- Car rentals near MD Anderson Cancer Center
- Standard Car Rentals near MD Anderson Cancer Center
- Car rentals near Houston Zoo
- Sportscar Car Rentals near Houston Zoo
- Car rentals near Hermann Park
- Car rentals near Rice University
- Pickup Car Rentals near Rice University
- Suv Car Rentals near Rice University
- Van Car Rentals near Rice University
- Car rentals near James Turrell's Twilight Epiphany Skyscape
- Car rentals near Museum District
- Thrifty Car Rental Rental Cars in Museum District
- Hertz Rental Cars in Museum District
- Alamo Rent A Car Rental Cars in Museum District
- Pickup Car Rentals in Museum District
- Sixt Rental Cars in Museum District
- Discount Quebec Rental Cars in Museum District
- Budget Rental Cars in Museum District
- Enterprise Rental Cars in Museum District
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.