Texas Medical Center Vacations
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Your Texas Medical Center Vacation
Texas Medical Center is calling! Whatever type of break you're organizing, you can see and experience the best of this neighborhood with a Texas Medical Center vacation package. Your trip to Texas Medical Center wouldn't be complete without a stop at top attractions nearby such as Houston Zoo, Houston Natural Science Museum and Childrens Museum of Houston. Whatever your travel plans or the size of your budget, booking a perfect Texas Medical Center vacation is quick and easy with Expedia.
Price found within the past 48 hours. Click for updated prices.
- Kompose Residences Houston Cy-Fair
Aug 13 - Aug 16Kompose Residences Houston Cy-Fair + Flight
Houston3 nights9.4/10 - Exceptional (582 reviews)"Clean room, Good breakfas"Reviewed June 4, 2026Roundtrip • Atlanta (ATL) - Houston (IAH)ATL - IAH • Nonstop IAH - ATL • Nonstop$396$294found 2 days agoper traveler - Experience a First Class Stay - 2 BDRM
Aug 13 - Aug 16Experience a First Class Stay - 2 BDRM + Flight
Humble3 nights8.0/10 - Very Good (5 reviews)"This people have water that smells like poop. Sewage water is what they use for water. Remnants of trash, sticky nastiness in drawers, air vents falling off ceilings. Random kids belts found? Candy stuck to floor? Trash wasn’t even taken out. Mind you I have kids that found these things as well. Oh and don’t even try and ask for them to refund you for their disgusting rental. They will give you the run around and then IGNORE YOU. Awful establishment and these people NEED TO BE SHUTDOWN."Reviewed March 11, 2022Roundtrip • Atlanta (ATL) - Houston (IAH)ATL - IAH • Nonstop IAH - ATL • Nonstop - Luxury 3BR for Families Nurses and Group
Aug 13 - Aug 16Luxury 3BR for Families Nurses and Group + Flight
Northside3 nightsRoundtrip • Atlanta (ATL) - Houston (IAH)ATL - IAH • Nonstop IAH - ATL • Nonstop - TUSCAN VILLA
Jul 8 - Jul 13TUSCAN VILLA + Flight
Greater Uptown5 nights2.0/10 - (3 reviews)Roundtrip • Atlanta (ATL) - Houston (IAH)ATL - IAH • Nonstop IAH - ATL • Nonstop - Holiday Inn Club Vacations Galveston Seaside Resort by IHG
Jul 30 - Aug 2Holiday Inn Club Vacations Galveston Seaside Resort by IHG + Flight
West End3 nights8.8/10 - Excellent (838 reviews)"We enjoyed our stay. However, there are a few “tips” for future travelers. The website is misleading. Only “Signature” guests have beachfront access; the majority have to cross a busy road and go under the “Signature “ building to get to the beach. You can use beach chairs free of charge by going to the first floor at Signature. We weren’t aware of this & happened upon it by pure luck! The bugs are horrendous. Do NOT walk on the grass or you will be attacked by some black bugs. Request a..."Reviewed June 2, 2026Roundtrip • Atlanta (ATL) - Houston (IAH)ATL - IAH • Nonstop IAH - ATL • Nonstop
Where to stay in Texas Medical Center
Find the best Texas Medical Center areas and neighborhoods for the activities you enjoy most. Learn more about Texas Medical Center
Downtown Houston
3 out of top 10 points of interest in this area
4.5/5(2,329 area reviews)
Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.
Texas Medical Center Hotel Deals
Blossom Hotel Houston, Curio Collection by Hilton
7118 Bertner Ave Houston TX
Fully refundableReserve now, pay when you stay
$137 nightly
The price is $160 total per night from Jul 5 to Jul 6
$160 total
Jul 5 - Jul 6
Total with taxes and fees
9/10 Wonderful! (3,853 reviews)
"Amazing staff - and amenities super nice!"
Reviewed on Jun 2, 2026
Hilton Houston Plaza/Medical Center
6633 Travis St Houston TX
Fully refundableReserve now, pay when you stay
$135 nightly
The price is $158 total per night from Jul 5 to Jul 6
$158 total
Jul 5 - Jul 6
Total with taxes and fees
8.4/10 Very Good! (1,948 reviews)
"Clean, quite and spacious."
Reviewed on Jun 1, 2026
Hyatt Place Houston Medical Center
7329 FANNIN STREET Building 2 Houston TX
$128 nightly
The price is $149 total per night from Jun 11 to Jun 12
$149 total
Jun 11 - Jun 12
Total with taxes and fees
9.2/10 Wonderful! (2,513 reviews)
"Very nice and convenient place near the Medical district. Good breakfast buffet."
Reviewed on Jun 4, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Texas Medical Center
NRG Stadium
4.5/5(634 reviews)
Catch an event at NRG Stadium during your trip to Houston. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
NASA Johnson Space Center
4.5/5(1,231 reviews)
After visiting NASA Johnson Space Center, make a plan to see the other sights and activities in Houston. Amble around the area's lakeside or attend a sporting event.
Daikin Park
4.5/5(915 reviews)
Catch an event at Daikin Park during your trip to Houston. Experience the lively festivals and entertainment choices in this vibrant area.
Things to do
Space Center Houston Admission Ticket
$33
per adult
92% of travellers recommend
Houston: Space Center Houston Admission Ticket
$30
per adult
92% of travellers recommend
NASA's Space Center & Official Houston City Tour with tickets
$109
per adult
92% of travellers recommend
Explore a world of travel with Expedia
- Houston Hotels
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- Houston Zoo
- Md Anderson Cancer Center
- Hermann Park
- Rice University
- Reckling Park
- Houston Vacations
- Rice Stadium
- Miller Outdoor Theater
- Nrg Stadium
- Visit Astrodome
- James Turrell's Twilight Epiphany Skyscape
- Houston Natural Science Museum
- Houston Museum of Fine Arts
- Nrg Park
- Museum District Vacations
- Children's Museum of Houston
- Holocaust Museum Houston
- Cullen Sculpture Garden
- Visit Riverside Terrace
- Buffalo Soldiers National Museum
- Visit Museum District
- Car rentals near Houston
- Car rentals near MD Anderson Cancer Center
- Standard Car Rentals near MD Anderson Cancer Center
- Car rentals near Houston Zoo
- Sportscar Car Rentals near Houston Zoo
- Car rentals near Hermann Park
- Car rentals near Rice University
- Pickup Car Rentals near Rice University
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- Car rentals near James Turrell's Twilight Epiphany Skyscape
- Car rentals near Museum District
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- Sixt Rental Cars in Museum District
- Discount Quebec Rental Cars in Museum District
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- Enterprise Rental Cars in Museum District
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.