Texas Medical Center Vacations from $157

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Your Texas Medical Center Vacation

Texas Medical Center is calling! Whatever type of break you're organizing, you can see and experience the best of this neighborhood with a Texas Medical Center vacation package. Your trip to Texas Medical Center wouldn't be complete without a stop at top attractions nearby such as Houston Zoo, Houston Natural Science Museum and Childrens Museum of Houston. Whatever your travel plans or the size of your budget, booking a perfect Texas Medical Center vacation is quick and easy with Expedia.

The Latest Texas Medical Center Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Stay Inn & Suites
Hampton Inn & Suites Houston Heights I-10
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Kozy Houston North
Blossom Hotel Houston, Curio Collection by Hilton

Where to stay in Texas Medical Center

Find the best Texas Medical Center areas and neighborhoods for the activities you enjoy most. Learn more about Texas Medical Center

Texas Medical Center Hotel Deals

Blossom Hotel Houston, Curio Collection by Hilton

Blossom Hotel Houston, Curio Collection by Hilton

4 out of 5
7118 Bertner Ave Houston TX
Fully refundableReserve now, pay when you stay
$161 nightly
The price is $188 total per night from Feb 8 to Feb 9
$188 total
Feb 8 - Feb 9
Total with taxes and fees
9/10 Wonderful! (3,711 reviews)
Staff was great. Beautiful room and view. The only negative issue was that the room smelled like stale smoke and needed to be completely sanitized. Still highly recommended.

Reviewed on Jan 29, 2026

Blossom Hotel Houston, Curio Collection by Hilton
Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

4.5 out of 5
6633 Travis St Houston TX
$91 nightly
The price is $106 total per night from Feb 22 to Feb 23
$106 total
Feb 22 - Feb 23
Total with taxes and fees
8.2/10 Very Good! (1,827 reviews)
Room was excellent.

Reviewed on Jan 29, 2026

Hilton Houston Plaza/Medical Center
Hyatt Place Houston Medical Center

Hyatt Place Houston Medical Center

3 out of 5
7329 FANNIN STREET Building 2 Houston TX
Fully refundableReserve now, pay when you stay
$117 nightly
The price is $137 total per night from Feb 7 to Feb 8
$137 total
Feb 7 - Feb 8
Total with taxes and fees
9/10 Wonderful! (2,295 reviews)
Excellent staff, large, spacious, clean room.

Reviewed on Jan 30, 2026

Hyatt Place Houston Medical Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.