Texas Medical Center Vacations from $240
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Your Texas Medical Center Vacation
Texas Medical Center is calling! Whatever type of break you're organizing, you can see and experience the best of this neighborhood with a Texas Medical Center vacation package. Your trip to Texas Medical Center wouldn't be complete without a stop at top attractions nearby such as Houston Zoo, Houston Natural Science Museum and Childrens Museum of Houston. Whatever your travel plans or the size of your budget, booking a perfect Texas Medical Center vacation is quick and easy with Expedia.
The Latest Texas Medical Center Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Hyatt Place Houston/Galleria
Greater Uptown
Save 100% on your flight
Price was $368, price is now $240 per person
$240
per person
Aug 23 - Aug 26
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Houston (IAH)
8.8/10 Excellent! (1,506 reviews)
Bonito lugar limpio, servicio atento pero el desayuno incluido muy limitado
Reviewed on Jul 1, 2026
Margaritaville Lake Resort, Lake Conroe/Houston
Save 100% on your flight
Price was $631, price is now $393 per person
$393
per person
Sep 13 - Sep 17
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Houston (IAH)
8.2/10 Very Good! (1,065 reviews)
When we arrived our room was not ready. We had to wait an hr for our room and that’s because I kept asking. The staff didn’t seem to care. Could improve
Reviewed on Jul 2, 2026
Experience a First Class Stay - 2 BDRM
Save 100% on your flight
Price was $831, price is now $573 per person
$573
per person
Aug 17 - Aug 21
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Houston (IAH)
8/10 Very Good! (5 reviews)
This people have water that smells like poop. Sewage water is what they use for water. Remnants of trash, sticky nastiness in drawers, air vents falling off ceilings. Random kids belts found? Candy stuck to floor? Trash wasn’t even taken out. Mind you I have kids that found these things as well.
Oh and don’t even try and ask for them to refund you for their disgusting rental. They will give you the run around and then IGNORE YOU. Awful establishment and these people NEED TO BE SHUTDOWN.
Reviewed on Mar 11, 2022
Heritage Place Houston Brookhollow
Lazybrook/Timbergrove
Price was $492, price is now $341 per person
$341
per person
Aug 18 - Aug 22
found 1 day ago
Roundtrip flight included
Baltimore (BWI) to Houston (IAH)
8.6/10 Excellent! (1,057 reviews)
I like this place because it’s so clean and fresher. I love the smell when u walk in . Thank you so much
Reviewed on Jun 30, 2026
Where to stay in Texas Medical Center
Find the best Texas Medical Center areas and neighborhoods for the activities you enjoy most. Learn more about Texas Medical Center
Downtown Houston
3 out of top 10 points of interest in this area
4.5/5(2,329 area reviews)
Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.
Texas Medical Center Hotel Deals
Blossom Hotel Houston, Curio Collection by Hilton
7118 Bertner Ave Houston TX
Fully refundableReserve now, pay when you stay
$125 nightly
The price is $146 total per night from Aug 2 to Aug 3
$146 total
Aug 2 - Aug 3
Total with taxes and fees
9/10 Wonderful! (3,811 reviews)
"Booked a 2 room suite for an hefty price… specifically to have 2ROOMS.. and they gave my room to someone else. They made us take 2 rooms on separate floors but only after we had to use the room they gave us for a night which entailed sharing a bed.. totally not ok! And it ruined the vibe. Totally ..."
Reviewed on Jul 1, 2026
Hilton Houston Plaza/Medical Center
6633 Travis St Houston TX
Fully refundableReserve now, pay when you stay
$88 nightly
The price is $103 total per night from Jul 12 to Jul 13
$103 total
Jul 12 - Jul 13
Total with taxes and fees
8.4/10 Very Good! (1,988 reviews)
"I’m very happy with my stay at the Hilton. Friendly staff and clean rooms"
Reviewed on Jul 2, 2026
Hyatt Place Houston Medical Center
7329 FANNIN STREET Building 2 Houston TX
Fully refundableReserve now, pay when you stay
$128 nightly
The price is $149 total per night from Jul 19 to Jul 20
$149 total
Jul 19 - Jul 20
Total with taxes and fees
9.2/10 Wonderful! (2,582 reviews)
"The issues we had; we were there from Thurs to Sunday and never saw cleaning staff. I even told staff to clean and they didn’t. Also, we called down for clean towels and they never came. Had to go down to get them ourselves. Also, there is no 24 hr shuttle as advertised. It’s only for the Medical ..."
Reviewed on Jun 30, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Things to do
Houston: Space Center Houston Admission Ticket
$30
per adult
92% of travellers recommend
Houston's Official City & Mural Tour!
$80
per adult
88% of travellers recommend
NASA's Space Center & Official Houston City Tour with tickets
$109
per adult
92% of travellers recommend
Explore a world of travel with Expedia
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- Main Street Theater - Rice Village
- Cy Twombly Gallery
- Menil Collection
- Alley Theater
- Holocaust Museum Houston
- Saint Arnold Brewery
- Houston Zoo
- Highland Village
- Gerald D. Hines Waterwall Park
- House of Blues Houston
- Six Flags Hurricane Harbor
- Houston Vacations
- Md Anderson Cancer Center
- Discovery Green
- Houston Natural Science Museum
- Christ Church Cathedral
- Kemah Boardwalk
- Theatre Under The Stars
- Houston Museum of Fine Arts
- North Houston Vacations
- Space Center Houston
- Harris Health System - Ben Taub General Hospital
- Color Factory Houston
- Wortham Center
- River Oaks Country Club
- Continental Club
- Visit Houston
- The Chapel of St. Basil
- Allen's Landing Park
- Houston Arboretum and Nature Center
- Greenway Plaza
- Buffalo Bayou Park
- Meyerland Plaza Shopping Center
- Cullen Sculpture Garden
- Hermann Park
- Bayou Place
- Houston JPMorgan Chase Tower
- George R. Brown Convention Center
- Traders Village
- Rice University
- Children's Museum of Houston
- Houston City Hall
- Nrg Stadium
- South Central Houston Vacations
- Midtown Vacations
- Memorial Vacations
- Downtown Aquarium
- Williams Tower
- Giant Beatles Statues
- Houston Sports Museum
- Bayou Bend Collection and Gardens
- Daikin Park
- Rothko Chapel
- Health Museum
- Downtown Houston Vacations
- Kinder Lake
- Buffalo Soldiers National Museum
- Sylvan Beach Park
- Shell Energy Stadium
- Jesse H. Jones Hall
- Houston Police Officer Memorial
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.