Texas Medical Center Vacations from $255
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Your Texas Medical Center Vacation
Texas Medical Center is calling! Whatever type of break you're organizing, you can see and experience the best of this neighborhood with a Texas Medical Center vacation package. Your trip to Texas Medical Center wouldn't be complete without a stop at top attractions nearby such as Houston Zoo, Houston Natural Science Museum and Childrens Museum of Houston. Whatever your travel plans or the size of your budget, booking a perfect Texas Medical Center vacation is quick and easy with Expedia.
The Latest Texas Medical Center Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Hampton Inn & Suites Houston Heights I-10
Washington Ave./ Memorial Park
Save 100% on your flight
Price was $427, price is now $255 per person
$255
per person
Apr 17 - Apr 20
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Houston (IAH)
9/10 Wonderful! (1,003 reviews)
Great stay overall! The room was clean, comfortable, and the staff was super friendly. Loved the location and the amenities — definitely worth it. I’d stay here again!
Reviewed on Jan 20, 2026
Margaritaville Lake Resort, Lake Conroe/Houston
Save 100% on your flight
Price was $617, price is now $423 per person
$423
per person
Apr 10 - Apr 13
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Houston (IAH)
8.2/10 Very Good! (1,006 reviews)
Clean, very well done, customer service was above and beyond in all aspects. Girls loved the heated pool, lazy river and arcade room theost!
Reviewed on Jan 26, 2026
Holiday Inn Club Vacations Galveston Beach Resort by IHG
West End
Price was $515, price is now $356 per person
$356
per person
Mar 18 - Mar 21
found 17 hours ago
Roundtrip flight included
Chicago (ORD) to Houston (IAH)
8.8/10 Excellent! (1,006 reviews)
Room was good. The staff was great! I was very frustrated that at no time when reserving this hotel that i would be required to attend a 90 minute (actually took 2+ hours) presentation on purchasing a timeshare with Holiday Inn.
Reviewed on Jan 7, 2026
Kompose Residences Houston Cy-Fair
Save 100% on your flight
Price was $377, price is now $261 per person
$261
per person
Apr 2 - Apr 5
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Houston (IAH)
10/10 Exceptional! (2 reviews)
very clean room with tons of accomodations, breakfast was good
Reviewed on Jan 28, 2026
Where to stay in Texas Medical Center
Find the best Texas Medical Center areas and neighborhoods for the activities you enjoy most. Learn more about Texas Medical Center
Downtown Houston
3 out of top 10 points of interest in this area
4.5/5(2,300 area reviews)
Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.
Texas Medical Center Hotel Deals
Blossom Hotel Houston, Curio Collection by Hilton
7118 Bertner Ave Houston TX
Fully refundableReserve now, pay when you stay
$161 nightly
The price is $188 total per night from Feb 8 to Feb 9
$188 total
Feb 8 - Feb 9
Total with taxes and fees
9/10 Wonderful! (3,711 reviews)
Staff was great. Beautiful room and view. The only negative issue was that the room smelled like stale smoke and needed to be completely sanitized. Still highly recommended.
Reviewed on Jan 29, 2026
Hilton Houston Plaza/Medical Center
6633 Travis St Houston TX
Fully refundableReserve now, pay when you stay
$91 nightly
The price is $107 total per night from Feb 15 to Feb 16
$107 total
Feb 15 - Feb 16
Total with taxes and fees
8.2/10 Very Good! (1,832 reviews)
Clean room, staff was super helpful
Reviewed on Jan 25, 2026
Hyatt Place Houston Medical Center
7329 FANNIN STREET Building 2 Houston TX
Fully refundableReserve now, pay when you stay
$117 nightly
The price is $137 total per night from Feb 6 to Feb 7
$137 total
Feb 6 - Feb 7
Total with taxes and fees
9/10 Wonderful! (2,281 reviews)
Clean room, good included breakfast, spacious room, and good customer service by staff.
Reviewed on Jan 24, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Texas Medical Center
Texas Children's Hospital
4.5/5(26 reviews)
Though Texas Children's Hospital might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here.
MD Anderson Cancer Center
4.5/5(788 reviews)
Though MD Anderson Cancer Center might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here.
Harris Health System - Ben Taub General Hospital
Though Harris Health System - Ben Taub General Hospital might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here.
Things to do
Houston: Houston Botanic Garden Entry Ticket
$12
per adult
80% of travellers recommend
Astroville Tunnel Tour of Downtown Houston (Air-Conditioned)
$25
per adult
100% of travellers recommend
Houston Museum of Natural Science: Cockrell Butterfly Center
$15
per adult
100% of travellers recommend
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- Houston Zoo
- MD Anderson Cancer Center
- Hermann Park
- Rice University
- Reckling Park
- Houston Vacations
- Rice Stadium
- Miller Outdoor Theater
- NRG Stadium
- Visit Astrodome
- James Turrell's Twilight Epiphany Skyscape
- Houston Natural Science Museum
- Houston Museum of Fine Arts
- NRG Park
- Houston Museum District Vacations
- Children's Museum of Houston
- Holocaust Museum Houston
- Cullen Sculpture Garden
- Visit Riverside Terrace
- Buffalo Soldiers National Museum
- Visit Houston Museum District
- Car rentals near Houston
- Car rentals near MD Anderson Cancer Center
- Standard Car Rentals near MD Anderson Cancer Center
- Car rentals near Houston Zoo
- Sportscar Car Rentals near Houston Zoo
- Car rentals near Hermann Park
- Car rentals near Rice University
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.