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Texas Medical Center Vacation Travel Guide

Accommodation in Texas Medical Center

Make a booking for one of the 11 Texas Medical Center hotels listed on Expedia's easy-to-use Texas Medical Center hotels guide before you travel.

Kick-start your search for the ideal Texas Medical Center base by investigating the latest offers at the high-ranking Hotel ZaZa Houston, at 5701 Main Street, and the Houston Marriott Medical Center, at 6580 Fannin Street. More budget-friendly options worth checking out are the Lexington Hotel Houston Medical Center, at 1025 Swanson Street, and the Hilton Houston Plaza / Medical Center, at 6633 Travis St.

It’s easy to book the getaway of your dreams when you search through our selection of Texas Medical Center vacations. Our goal? To create the perfect trip for you by providing the largest selection of vacation packages. Confidently book your getaway thanks to our trustworthy recommendations and verified consumer reviews from travelers just like you. Personalize your Texas Medical Center package with our myriad of hotel rooms and flight tickets, which help to create a vacation specifically for you. Simply sort through our selection and pick and choose the elements that best suit your preferences and price range.

Because we offer the best rates, you can book your travel reservations knowing you won’t find lower prices elsewhere. These discounts are so great, you’ll feel like you gained the title of the ultimate bargain hunter with our Texas Medical Center vacation package deals. Whether you’re looking to book multiple flights, stay at the fanciest hotel, or explore the hottest local attractions, you’ll find discounted travel arrangements within your budget right here. You shouldn’t have a care in the world when you go on vacation, so our discounts allow you to rest easy without giving your bank account a second thought. Save money on your vacation today and revel in your much-deserved getaway tomorrow.


Top Hotel Deals

See all 593 Hotels in Texas Medical Center
$81
Extended Stay America -Houston-Med Ctr-NRG Pk-Braeswood Blvd

Extended Stay America -Houston-Med Ctr-NRG Pk-Braeswood Blvd

1301 Braeswood Blvd, Houston
3.2
of 5, from 645 reviews
3.0 out of 5.0

Located in Texas Medical Center, this hotel is within 2 mi (3 km) of MD Anderson Cancer Center, Houston Zoo, and NRG Park. Houston Natural Science Museum and Children's Museum of Houston are also within 3 mi (5 km).

$109
Houston Marriott Medical Center/Museum District

Houston Marriott Medical Center/Museum District

6580 Fannin Street, Houston
4.3
of 5, from 676 reviews
4.5 out of 5.0

Located in Texas Medical Center, this hotel is within 1 mi (2 km) of MD Anderson Cancer Center, Houston Zoo, and Houston Natural Science Museum. Children's Museum of Houston and NRG Park are also within 3 mi (5 km).

Ideally Located 2bedroom/2bath Apartment at Texas Medical Center and NRG Stadium

Ideally Located 2bedroom/2bath Apartment at Texas Medical Center and NRG Stadium

2222 Maroneal Street, Houston
0.0 out of 5.0

Located in Texas Medical Center, this property is within 2 mi (3 km) of Houston Maritime Museum, Houston Zoo, and NRG Park. Houston Natural Science Museum and Children's Museum of Houston are also within 3 mi (5 km).

$71
Sheraton North Houston at George Bush Intercontinental

Sheraton North Houston at George Bush Intercontinental

15700 John F Kennedy Blvd, Houston
4.2
of 5, from 1,448 reviews
4.0 out of 5.0

Located 3 miles south of George Bush Intercontinental Airport in Houston, the Sheraton North Houston caters to business travelers and is close to many major businesses and tourist attractions.

$123
Hilton Americas - Houston

Hilton Americas - Houston

1600 Lamar Street, Houston
4.6
of 5, from 3,087 reviews
4.5 out of 5.0

Attached to the George R Brown convention center by sky bridge, Hilton Americas - Houston is across the street from Toyota Arena and 2 blocks from Minute Maid ballpark and the theater district.

$88
DoubleTree by Hilton Hotel & Suites Houston by the Galleria

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

5353 Westheimer Rd, Houston
3.8
of 5, from 423 reviews
4.5 out of 5.0

The hotel is a 4-minute walk from The Galleria, a fashionable mall housing over 400 boutiques and restaurants. Guests can admire dinosaur fossils at the Houston Museum of Natural Science, a 23-minute drive, or take a hike in scenic Memorial Park, an 8-minute cab ride from the hotel.

$63
Red Roof Inn Houston - IAH Airport

Red Roof Inn Houston - IAH Airport

15675 John F. Kennedy Blvd, Houston
3.4
of 5, from 1,177 reviews
2.5 out of 5.0

Situated near the airport, this motel is within 6 mi (10 km) of Houston Grand Prix, Houston Police Department Museum, and Greenspoint Mall. Golf Club of Houston and Humble Civic Center are also within 9 mi (15 km).

$174
The Houstonian Hotel, Club & Spa

The Houstonian Hotel, Club & Spa

111 N Post Oak Ln, Houston
4.7
of 5, from 1,091 reviews
5.0 out of 5.0

2 miles from the Galleria via complimentary shuttle, this urban oasis with acclaimed spa, aquatics center, and health club sits on 18 wooded acres; downtown Houston and the Museum District are within 9 miles.

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