Title: Texas Medical Center Vacation Packages 2026 from $173 | Expedia.com [Texas Medical Center Travel Guide](https://expedia.com/Houston-Texas-Medical-Center.dx6143504)[Hotels in Texas Medical Center](https://expedia.com/Texas-Medical-Center-Houston-Hotels.0-n6143504-0.Travel-Guide-Filter-Hotels)[Flights to Houston](https://expedia.com/Cheap-Flights-To-Houston.d178265.Travel-Guide-Flights)[Things to do in Houston](https://expedia.com/Things-To-Do-In-Houston.d178265.Travel-Guide-Activities)[Car Rentals in Texas Medical Center](https://expedia.com/Car-Rentals-In-Texas-Medical-Center.d6143504.Car-Rental-Guide) ![](https://images.trvl-media.com/place/6143504/24718cb1-d944-454b-b1a9-0c611d76d414.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Texas Medical Center Vacations from $173 ## Book a Hotel + Flight or Car together to unlock savings - ## Plan, book, travel with confidence - ### Better together Save up to $1,045 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Plan, book, and manage your trip all in one place ## Your Texas Medical Center Vacation Texas Medical Center is calling! Whatever type of break you're organizing, you can see and experience the best of this neighborhood with a Texas Medical Center vacation package. Your trip to Texas Medical Center wouldn't be complete without a stop at top attractions nearby such as [Houston Zoo](https://www.expedia.com/Houston-Zoo-South-Central-Houston.d6082223.Vacation-Attraction), [Houston Natural Science Museum](https://www.expedia.com/Houston-Natural-Science-Museum-South-Central-Houston.d501256.Vacation-Attraction) and [Childrens Museum of Houston](https://www.expedia.com/Childrens-Museum-Of-Houston-South-Central-Houston.d6082211.Vacation-Attraction). Whatever your travel plans or the size of your budget, booking a perfect Texas Medical Center vacation is quick and easy with Expedia. ## The Latest Texas Medical Center Vacation Packages Price found within the past 48 hours. Click for updated prices. ![Hilton Houston North](https://images.trvl-media.com/lodging/1000000/10000/900/809/72a26fde_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hilton Houston North Northside Save 100% on your flight $173 per person Apr 20 - Apr 22 found 1 day ago Roundtrip flight included Atlanta (ATL) to Houston (IAH) 8.2/10 Very Good! (1,011 reviews) The location is great . But it was one of the worst experiences I’ve ever had. When i arrived 1:00 pm i requested early check in and i was charged for it . Not expecting anything free . I was more than okay with the extra charge . The condo had not been cleaned. It took over 3 hours for housekeeping to arrive and prepare the condo. I was told by the front desk that because I booked through a third part ( Expedia I’m assuming) they were unable to assist me with any issues. Instead I was instructed to call a number in Arizona for help . Even for basic request like extra towels . Which was extremely inconvenient. The pillow were extremely dirty . I took photos and reported the issue . Housekeeping said they couldn’t replace them again call that Arizona number. Overall , this was a ver frustrating experience 😔 Reviewed on Mar 17, 2026 ![Hyatt Place Houston-North](https://images.trvl-media.com/lodging/1000000/70000/67500/67415/a3265ebf_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hyatt Place Houston-North Northside $291 per person May 1 - May 8 found 1 day ago Roundtrip flight included Atlanta (ATL) to Houston (IAH) 6.8/10 (1,430 reviews) Nice & clean very spacious but the hotel had a really bad shortage on towels. It was times we had to go & buy our own Reviewed on Mar 16, 2026 ![South Houston Inn & Suites Hobby Airport I 45](https://images.trvl-media.com/lodging/126000000/125420000/125413100/125413089/95f2d6eb_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### South Houston Inn & Suites Hobby Airport I 45 Southeast Houston Save 100% on your flight $197 per person May 8 - May 13 found 14 hours ago Roundtrip flight included Atlanta (ATL) to Houston (IAH) 5.8/10 (6 reviews) Staff was a plus... Check in at 3pm Had a wonderful stay. I was just upset at about 1:30 almost 2am. Someone tried to open my door glad I was up... It didn't make sense because the tv was on and I was laying down watching TV baby was sleep. Glad it happened to me and not her. Other than that I might stay again. Reviewed on Feb 16, 2026 ![Hampton Inn & Suites Houston Heights I-10](https://images.trvl-media.com/lodging/1000000/10000/500/490/e75c5d2e_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Hampton Inn & Suites Houston Heights I-10 Washington Ave./ Memorial Park Save 100% on your flight $215 per person Apr 20 - Apr 22 found 1 day ago Roundtrip flight included Atlanta (ATL) to Houston (IAH) 9/10 Wonderful! (1,008 reviews) The hotel was pretty good however the breakfast was pretty bad. Not hot milk for the coffee, the eggs were bad etc Reviewed on Mar 17, 2026 ![Holiday Inn Houston Downtown by IHG](https://images.trvl-media.com/lodging/9000000/8170000/8168200/8168134/50a1a294_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Holiday Inn Houston Downtown by IHG Downtown Houston Save 100% on your flight $331 per person Apr 30 - May 3 found 1 day ago Roundtrip flight included Atlanta (ATL) to Houston (IAH) 8.6/10 Excellent! (1,717 reviews) Under lots of renovations and they have a small shuttle for a big hotel. Reviewed on Mar 18, 2026 ## Where to stay in Texas Medical Center Find the best Texas Medical Center areas and neighborhoods for the activities you enjoy most. [Learn more about Texas Medical Center](https://expedia.com/Houston-Texas-Medical-Center.dx6143504) ![Illuminated paths and modern buildings create a vibrant atmosphere at Discovery Green in Houston, Texas during the evening](https://images.trvl-media.com/place/6082195/fa70078e-ab30-43a5-aa06-e3a763da2444.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Downtown Houston 3 out of top 10 points of interest in this area 4.5/5(2,300 area reviews) Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines. [Find hotel + flight trips in Downtown Houston](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Downtown%20Houston&DestID=800037&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods) ![Man at the famous Water Wall in Houston, Texas USA](https://images.trvl-media.com/place/501263/0678cf84-c367-4c94-a162-d3e16a0367a7.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### The Galleria 4.5/5(1,958 area reviews) Travelers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to make a stop by The Galleria and Williams Tower. [Find hotel + flight trips in The Galleria](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=The%20Galleria&DestID=501263&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods) ![EyeEm Custom Shoots Q4 2018](https://images.trvl-media.com/place/3000663145/5fc14982-6419-4f20-a21b-2dee7a209053.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Montrose 4/5(128 area reviews) Unique features of Montrose include the theaters and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area. [Find hotel + flight trips in Montrose](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Montrose&DestID=3000663145&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods) ![Taken from the parking garage. #UrbanJungle](https://images.trvl-media.com/place/1503/584a0ee8-b413-46fb-ad95-8f02fd4ce2b2.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Houston Central Business District If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more the city at Bell Station or Downtown Transit Center Station. [Find hotel + flight trips in Houston Central Business District](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Houston%20Central%20Business%20District&DestID=553248635976473213&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods) ![Phoenix midtown skyline with a Saguaro Cactus and other desert scenery in the foreground.](https://images.trvl-media.com/place/6282039/f3a43cb9-8929-48c1-b277-aa868fe68431.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Midtown 4.5/5(43 area reviews) Characterized by a vibrant nightlife and young residents, this central Houston neighborhood boasts Ensemble Theatre, the largest African-American theater company in the US, and various parks like Midtown Park and Elizabeth Baldwin Park. Easily accessible via METRORail Red Line. [Find hotel + flight trips in Midtown](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Midtown&DestID=6282039&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods) ## Texas Medical Center Hotel Deals ![Blossom Hotel Houston, Curio Collection by Hilton](https://images.trvl-media.com/lodging/59000000/58990000/58985900/58985846/w3837h2505x3y0-1cfabad9_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Blossom Hotel Houston, Curio Collection by Hilton 7118 Bertner Ave Houston TX Fully refundableReserve now, pay when you stay $161 nightly $188 total Apr 12 - Apr 13 Total with taxes and fees 9/10 Wonderful! (3,767 reviews) Hotel is nice. Staff from check in, bar to dinner are the worst. The bartender on the 13th floor is useless. This was my third time staying and he’s been the worst every time. Back to Zaza for me for great service! Reviewed on Mar 18, 2026 [](https://expedia.com/Hotel-Search?startDate=4%2F12%2F2026&endDate=4%2F13%2F2026&selected=58985846&PinnedHotelID=58985846&HadPinnedHotel=true®ionId=6143504) ![Hilton Houston Plaza/Medical Center](https://images.trvl-media.com/lodging/1000000/30000/25200/25188/77443f8e_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hilton Houston Plaza/Medical Center 6633 Travis St Houston TX Fully refundableReserve now, pay when you stay $100 nightly $117 total Mar 29 - Mar 30 Total with taxes and fees 8.4/10 Very Good! (1,859 reviews) Antonio, the front desk clerk, was amazingly nice. He made the check-in process smooth and brisk, like 2 minutes brick. He was very pleasant and informative. The location, as a Molecular Biologist whom works at several labs in the Medical Center, was perfectly placed. As a Houstonian, you are in ... Reviewed on Mar 18, 2026 [](https://expedia.com/Hotel-Search?startDate=3%2F29%2F2026&endDate=3%2F30%2F2026&selected=25188&PinnedHotelID=25188&HadPinnedHotel=true®ionId=6143504) ![The Westin Houston Medical Center/Museum District](https://images.trvl-media.com/lodging/40000000/39620000/39618700/39618635/a994a387_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### The Westin Houston Medical Center/Museum District 1709 DRYDEN ROAD Houston TX Fully refundableReserve now, pay when you stay $182 nightly $211 total Apr 3 - Apr 4 Total with taxes and fees 9.2/10 Wonderful! (1,131 reviews) The hotel is modern and very nice. Reviewed on Mar 18, 2026 [](https://expedia.com/Hotel-Search?startDate=4%2F3%2F2026&endDate=4%2F4%2F2026&selected=39618635&PinnedHotelID=39618635&HadPinnedHotel=true®ionId=6143504) [See all 6,468 properties in Texas Medical Center](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=3%2F20%2F2026&endDate=3%2F21%2F2026®ionId=6143504) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Vacations [](https://expedia.com/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Vacations [](https://expedia.com/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Kid Friendly Vacations [](https://expedia.com/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Kid_Friendly%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/04/29/frCA_Sejours_golf-Portugal.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Golf Vacations [](https://expedia.com/lp/theme-vacations/golf-vacations?rfrr=editorial.Golf_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/07/15/US_Luxury_VR_Miami.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Luxury Vacations [](https://expedia.com/lp/theme-vacations/luxury-vacations?rfrr=editorial.Luxury_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/08/29/romantic.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Romantic Vacations [](https://expedia.com/lp/theme-vacations/romantic-vacations?rfrr=editorial.Romantic_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/31952_v1_atfraraski22_insta_4.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Ski Vacations [](https://expedia.com/lp/theme-vacations/ski-vacations?rfrr=editorial.Ski_Vacations.click) ![Gay Friendly Vacations](https://forever.travel-assets.com/flex/flexmanager/images/2023/06/15/LGBTQIA_Holiday_Package.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) LGBTQ Friendly Vacations [](https://expedia.com/lp/theme-holidays/gay-friendly-holidays?rfrr=editorial.LGBTQ_Friendly%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2017/07/05/170615_Adventure_1320_2.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Adventure Vacations [](https://expedia.com/lp/theme-vacations/adventure-vacations?rfrr=editorial.Adventure_Vacations.click) ![Vacations in Month](https://forever.travel-assets.com/flex/flexmanager/images/2023/05/10/mesog-34434-card-venice.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Where to go when [](https://expedia.com/lp/b/where-to-go-when?rfrr=editorial.Where_to%20go%20when.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/21/honeymoon_hawaii.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Honeymoon Vacations [](https://expedia.com/lp/theme-vacations/honeymoon-vacations?rfrr=editorial.Honeymoon_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/Mountain-vacations.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Mountain Vacations [](https://expedia.com/lp/theme-vacations/mountain-vacations?rfrr=editorial.Mountain_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/fishing-vacations-2.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Fishing Vacations [](https://expedia.com/lp/theme-vacations/fishing-vacations?rfrr=editorial.Fishing_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2019/05/16/Hyatt%20Zilara%20Cancun%20-%20All%20Inclusive%20-%20Adults%20Only.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Adults Only Vacations [](https://expedia.com/lp/theme-vacations/adults-only-vacations?rfrr=editorial.Adults_Only%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/23/waterpark-vacations.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Waterpark Vacations [](https://expedia.com/lp/theme-vacations/waterpark-vacations?rfrr=editorial.Waterpark_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/08/Caribean_scuba_diving.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Scuba Diving Vacations [](https://expedia.com/lp/theme-vacations/scuba-diving-vacations?rfrr=editorial.Scuba_Diving%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/05/08/aruba_yoga.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Yoga Vacations [](https://expedia.com/lp/theme-vacations/yoga-vacations?rfrr=editorial.Yoga_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2023/04/04/EPS-RBC-SummerBeachVacations-AdobeStock_206356322.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Cheap Vacations [](https://expedia.com/lp/theme-vacations/cheap-vacations?rfrr=editorial.Cheap_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2024/06/26/1175883311.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Solo Vacations [](https://expedia.com/lp/b/vacations/solo-vacations?rfrr=editorial.Solo_Vacations.click) ### Discover the most popular places to visit in Texas Medical Center ![Houston_TexasChildrensHospital_553248635389801905_9](https://images.trvl-media.com/place/553248635389801905/db4dee74-4310-41e3-8220-625d7fc800e9.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Texas Children's Hospital 4.5/5(26 reviews) Though Texas Children's Hospital might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here. [](https://expedia.com/Texas-Childrens-Hospital-Texas-Medical-Center.d553248635389801905.Vacation-Attraction) #### MD Anderson Cancer Center 4.5/5(788 reviews) Though MD Anderson Cancer Center might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here. [](https://expedia.com/MD-Anderson-Cancer-Center-Texas-Medical-Center.d6248539.Vacation-Attraction) #### Harris Health System - Ben Taub General Hospital Though Harris Health System - Ben Taub General Hospital might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here. [](https://expedia.com/Harris-Health-System-Ben-Taub-General-Hospital-Texas-Medical-Center.d553248635997987089.Vacation-Attraction) ### Things to do ![Astroville Tunnel Tour of Downtown Houston](https://mediaim.expedia.com/localexpert/1358845/93d97319-081a-4fec-9e57-9de4737dfee7.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Astroville Tunnel Tour of Downtown Houston (Air-Conditioned) $25 per adult **100%** of travellers recommend [](https://expedia.com/things-to-do/astroville-tunnel-tour-of-downtown-houston-air-conditioned.a1358845.activity-details) ![Houston Museum of Natural Science: Cockrell Butterfly Center](https://mediaim.expedia.com/localexpert/44625315/13581a0d-ea47-46d7-8fcf-d3fc7aa4909c.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Houston Museum of Natural Science: Butterfly Center Ticket $15 per adult **100%** of travellers recommend [](https://expedia.com/things-to-do/houston-museum-of-natural-science-butterfly-center-ticket.a44625315.activity-details) ![Houston: Houston Botanic Garden Entry Ticket](https://mediaim.expedia.com/localexpert/46150646/bfc34474-c86f-4151-a485-5cc63efe2aab.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Houston: Houston Botanic Garden Entry Ticket $12 per adult **80%** of travellers recommend [](https://expedia.com/things-to-do/houston-houston-botanic-garden-entry-ticket.a46150646.activity-details) [See all activities in Houston](https://expedia.com/things-to-do/search?rid=6143504) ## Explore a world of travel with Expedia - 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Savings not available on all packages.