Texas Medical Center Vacations from $278
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Your Texas Medical Center Vacation
Texas Medical Center is calling! Whatever type of break you're organizing, you can see and experience the best of this neighborhood with a Texas Medical Center vacation package. Your trip to Texas Medical Center wouldn't be complete without a stop at top attractions nearby such as Houston Zoo, Houston Natural Science Museum and Childrens Museum of Houston. Whatever your travel plans or the size of your budget, booking a perfect Texas Medical Center vacation is quick and easy with Expedia.
The Latest Texas Medical Center Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Hampton Inn & Suites Houston Heights I-10
Washington Ave./ Memorial Park
Save 100% on your flight
Price was $473, price is now $278 per person
$278
per person
Apr 10 - Apr 13
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Houston (IAH)
9/10 Wonderful! (1,003 reviews)
Great stay overall! The room was clean, comfortable, and the staff was super friendly. Loved the location and the amenities — definitely worth it. I’d stay here again!
Reviewed on Jan 20, 2026
Kompose Residences Houston Cy-Fair
Save 100% on your flight
Price was $468, price is now $294 per person
$294
per person
Apr 1 - Apr 5
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Houston (IAH)
10/10 Exceptional! (2 reviews)
Enjoyed our stay! Check in was easy and seamless. Only issue was when we made it up to our room, we pull out the sofa bed and it was covered in dirty and grime. We went down to the front desk and showed a video of how we found the bed, and the front immediately rectified it by moving our room. We weren't offered an apology, but glad we got some action. From the outside the hotel looks dated, but on the inside it had a modern upgraded feel (except the showers. The showers were definitely dated which confused us sort of lol.)
Outside of that staff was polite, decor was cute, pricing was cheat so can't beat that. We will more than likely be back :).
Reviewed on Feb 3, 2026
Blossom Hotel Houston, Curio Collection by Hilton
Texas Medical Center
Save 100% on your flight
Price was $495, price is now $338 per person
$338
per person
Apr 10 - Apr 13
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Houston (IAH)
9/10 Wonderful! (3,554 reviews)
Room was clean, bed very comfortable, great coffee in room, check-in a little surprising because we weren’t expecting the valet-only $50+tip parking fee.
Reviewed on Feb 3, 2026
Holiday Inn Club Vacations Galveston Seaside Resort by IHG
West End
Price was $643, price is now $452 per person
$452
per person
Mar 20 - Mar 23
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Houston (IAH)
8.6/10 Excellent! (627 reviews)
Unit was not as listed, some amenities restricted
Reviewed on Feb 2, 2026
Holiday Inn Club Vacations Galveston Beach Resort by IHG
West End
Price was $596, price is now $420 per person
$420
per person
Mar 20 - Mar 23
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Houston (IAH)
8.8/10 Excellent! (1,006 reviews)
Room was good. The staff was great! I was very frustrated that at no time when reserving this hotel that i would be required to attend a 90 minute (actually took 2+ hours) presentation on purchasing a timeshare with Holiday Inn.
Reviewed on Jan 7, 2026
Where to stay in Texas Medical Center
Find the best Texas Medical Center areas and neighborhoods for the activities you enjoy most. Learn more about Texas Medical Center
Downtown Houston
3 out of top 10 points of interest in this area
4.5/5(2,300 area reviews)
Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.
Texas Medical Center Hotel Deals
Blossom Hotel Houston, Curio Collection by Hilton
7118 Bertner Ave Houston TX
Fully refundableReserve now, pay when you stay
$174 nightly
The price is $203 total per night from Feb 8 to Feb 9
$203 total
Feb 8 - Feb 9
Total with taxes and fees
9/10 Wonderful! (3,687 reviews)
Staff was pleasant and helpful. Room was clean comfortable and spacious
Reviewed on Jan 31, 2026
Hyatt Place Houston Medical Center
7329 FANNIN STREET Building 2 Houston TX
Fully refundableReserve now, pay when you stay
$117 nightly
The price is $137 total per night from Feb 8 to Feb 9
$137 total
Feb 8 - Feb 9
Total with taxes and fees
9/10 Wonderful! (2,295 reviews)
Excellent staff, large, spacious, clean room.
Reviewed on Jan 30, 2026
Hilton Houston Plaza/Medical Center
6633 Travis St Houston TX
Fully refundableReserve now, pay when you stay
$74 nightly
The price is $86 total per night from Feb 8 to Feb 9
$86 total
Feb 8 - Feb 9
Total with taxes and fees
8.4/10 Very Good! (1,827 reviews)
Clean room, attentive and friendly staff, good resources
Reviewed on Feb 4, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Texas Medical Center
Texas Children's Hospital
Though Texas Children's Hospital might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here.
MD Anderson Cancer Center
Though MD Anderson Cancer Center might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here.
Harris Health System - Ben Taub General Hospital
Though Harris Health System - Ben Taub General Hospital might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here.
Things to do
Houston: Houston Botanic Garden Entry Ticket
$12
per adult
80% of travellers recommend
Astroville Tunnel Tour of Downtown Houston (Air-Conditioned)
$25
per adult
100% of travellers recommend
Houston Museum of Natural Science: Cockrell Butterfly Center
$15
per adult
100% of travellers recommend
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- Houston Zoo
- MD Anderson Cancer Center
- Hermann Park
- Rice University
- Reckling Park
- Houston Vacations
- Rice Stadium
- Miller Outdoor Theater
- NRG Stadium
- Visit Astrodome
- James Turrell's Twilight Epiphany Skyscape
- Houston Natural Science Museum
- Houston Museum of Fine Arts
- NRG Park
- Houston Museum District Vacations
- Children's Museum of Houston
- Holocaust Museum Houston
- Cullen Sculpture Garden
- Visit Riverside Terrace
- Buffalo Soldiers National Museum
- Visit Houston Museum District
- Car rentals near Houston
- Car rentals near MD Anderson Cancer Center
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- Car rentals near Rice University
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.