Texas Medical Center Vacations from $227

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Your Texas Medical Center Vacation

Texas Medical Center is calling! Whatever type of break you're organizing, you can see and experience the best of this neighborhood with a Texas Medical Center vacation package. Your trip to Texas Medical Center wouldn't be complete without a stop at top attractions nearby such as Houston Zoo, Houston Natural Science Museum and Childrens Museum of Houston. Whatever your travel plans or the size of your budget, booking a perfect Texas Medical Center vacation is quick and easy with Expedia.

The Latest Texas Medical Center Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Heritage Place Houston Brookhollow
Hilton Houston North
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Hotel Saint Augustine
The Lancaster Hotel

Where to stay in Texas Medical Center

Find the best Texas Medical Center areas and neighborhoods for the activities you enjoy most. Learn more about Texas Medical Center

Texas Medical Center Hotel Deals

Hilton Houston Plaza/Medical Center

Hilton Houston Plaza/Medical Center

4.5 out of 5
6633 Travis St, Houston, TX
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $129 total per night from Oct 12 to Oct 13
$129 total
Oct 12 - Oct 13
Total with taxes and fees
8.2/10 Very Good! (1,603 reviews)
"Beautiful place. The staff was very helpful."

Reviewed on Sep 30, 2025

Hilton Houston Plaza/Medical Center
Blossom Hotel Houston

Blossom Hotel Houston

4 out of 5
7118 Bertner Ave, Houston, TX
Fully refundableReserve now, pay when you stay
$161 nightly
The price is $188 total per night from Oct 12 to Oct 13
$188 total
Oct 12 - Oct 13
Total with taxes and fees
9/10 Wonderful! (3,541 reviews)
"Amazing stay Clean, updated and quiet"

Reviewed on Oct 3, 2025

Blossom Hotel Houston
Hyatt Place Houston Medical Center

Hyatt Place Houston Medical Center

3 out of 5
7329 FANNIN STREET Building 2, Houston, TX
Fully refundableReserve now, pay when you stay
$140 nightly
The price is $163 total per night from Oct 9 to Oct 10
$163 total
Oct 9 - Oct 10
Total with taxes and fees
9/10 Wonderful! (2,001 reviews)
"Nice hotel. No issues"

Reviewed on Sep 27, 2025

Hyatt Place Houston Medical Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.