Texas Medical Center Vacations from $416
Book a Hotel + Flight or Car together to unlock savings
Your Texas Medical Center Vacation
Texas Medical Center is calling! Whatever type of break you're organizing, you can see and experience the best of this neighborhood with a Texas Medical Center vacation package. Your trip to Texas Medical Center wouldn't be complete without a stop at top attractions nearby such as Houston Zoo, Houston Natural Science Museum and Childrens Museum of Houston. Whatever your travel plans or the size of your budget, booking a perfect Texas Medical Center vacation is quick and easy with Expedia.
The Latest Texas Medical Center Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Home Place Inn
Willow Meadows/Willowbend Area
Price was $1,436, price is now $416 per person
$416
per person
Jun 25 - Jun 29
found 16 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Houston (IAH)
8.2/10 Very Good! (601 reviews)
AC was great. Not in the best area, but nothing happened.
Reviewed on Mar 29, 2026
Holiday Inn Club Vacations Galveston Seaside Resort by IHG
West End
Save 100% on your flight
Price was $783, price is now $524 per person
$524
per person
Jun 22 - Jun 26
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Houston (IAH)
8.8/10 Excellent! (770 reviews)
I was unaware that our room was on the 3rd floor and there was no elevator.
Reviewed on Apr 5, 2026
Holiday Inn Houston Downtown by IHG
Downtown Houston
Save 100% on your flight
Price was $1,126, price is now $770 per person
$770
per person
Jul 2 - Jul 5
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Houston (IAH)
8.6/10 Excellent! (1,763 reviews)
Did Not Use The Laundry.And Not To Many Stores In The Area.That Downtown Area Should Be Thriving...
Reviewed on Apr 9, 2026
Where to stay in Texas Medical Center
Find the best Texas Medical Center areas and neighborhoods for the activities you enjoy most. Learn more about Texas Medical Center
Downtown Houston
3 out of top 10 points of interest in this area
4.5/5(2,329 area reviews)
Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.
Texas Medical Center Hotel Deals
Blossom Hotel Houston, Curio Collection by Hilton
7118 Bertner Ave Houston TX
Fully refundableReserve now, pay when you stay
$137 nightly
The price is $160 total per night from May 10 to May 11
$160 total
May 10 - May 11
Total with taxes and fees
9/10 Wonderful! (3,775 reviews)
As a family pack with two kids, I used to love staying at Blossom anytime we visited Houston, but this was our last stay. There were several people pulling up in “hot boxed” vehicles (which to each their own but not family friendly), but the catalyst was coming downstairs at around 9pm to find a ...
Reviewed on Apr 9, 2026
Hilton Houston Plaza/Medical Center
6633 Travis St Houston TX
Fully refundableReserve now, pay when you stay
$100 nightly
The price is $117 total per night from Apr 19 to Apr 20
$117 total
Apr 19 - Apr 20
Total with taxes and fees
8.4/10 Very Good! (1,877 reviews)
Nice place and coming back
Reviewed on Apr 8, 2026
Hyatt Place Houston Medical Center
7329 FANNIN STREET Building 2 Houston TX
Fully refundableReserve now, pay when you stay
$128 nightly
The price is $149 total per night from Apr 19 to Apr 20
$149 total
Apr 19 - Apr 20
Total with taxes and fees
9.2/10 Wonderful! (2,439 reviews)
Second time staying at this hotel. I chose it for the convenience of location.
Reviewed on Apr 8, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Texas Medical Center
MD Anderson Cancer Center
4.5/5(802 reviews)
Though MD Anderson Cancer Center might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here.
Texas Children's Hospital
4.5/5(26 reviews)
Though Texas Children's Hospital might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here.
Harris Health System - Ben Taub General Hospital
Though Harris Health System - Ben Taub General Hospital might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here.
Things to do
Houston: Houston Botanic Garden Entry Ticket
$12
per adult
80% of travellers recommend
Astroville Tunnel Tour of Downtown Houston (Air-Conditioned)
$25
per adult
100% of travellers recommend
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- Houston Zoo
- Md Anderson Cancer Center
- Hermann Park
- Rice University
- Reckling Park
- Houston Vacations
- Rice Stadium
- Miller Outdoor Theater
- Nrg Stadium
- Visit Astrodome
- James Turrell's Twilight Epiphany Skyscape
- Houston Natural Science Museum
- Houston Museum of Fine Arts
- Nrg Park
- Museum District Vacations
- Children's Museum of Houston
- Holocaust Museum Houston
- Cullen Sculpture Garden
- Visit Riverside Terrace
- Buffalo Soldiers National Museum
- Visit Museum District
- Car rentals near Houston
- Car rentals near MD Anderson Cancer Center
- Standard Car Rentals near MD Anderson Cancer Center
- Car rentals near Houston Zoo
- Sportscar Car Rentals near Houston Zoo
- Car rentals near Hermann Park
- Car rentals near Rice University
- Pickup Car Rentals near Rice University
- Suv Car Rentals near Rice University
- Van Car Rentals near Rice University
- Car rentals near James Turrell's Twilight Epiphany Skyscape
- Car rentals near Museum District
- Thrifty Car Rental Rental Cars in Museum District
- Hertz Rental Cars in Museum District
- Alamo Rent A Car Rental Cars in Museum District
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- Sixt Rental Cars in Museum District
- Discount Quebec Rental Cars in Museum District
- Budget Rental Cars in Museum District
- Enterprise Rental Cars in Museum District
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.