Texas Medical Center Vacations from $174
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Your Texas Medical Center Vacation
Texas Medical Center is calling! Whatever type of break you're organizing, you can see and experience the best of this neighborhood with a Texas Medical Center vacation package. Your trip to Texas Medical Center wouldn't be complete without a stop at top attractions nearby such as Houston Zoo, Houston Natural Science Museum and Childrens Museum of Houston. Whatever your travel plans or the size of your budget, booking a perfect Texas Medical Center vacation is quick and easy with Expedia.
The Latest Texas Medical Center Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Hotel Royale IAH Airport North Houston I-45
Westfield
Price was $246, price is now $174 per person
$174
per person
Apr 24 - Apr 27
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Houston (IAH)
2/10 (2 reviews)
The property was organized and welcoming.
Check-in and check-out were easy.
Reviewed on Dec 28, 2025
Hampton Inn & Suites Houston Heights I-10
Washington Ave./ Memorial Park
Price was $378, price is now $273 per person
$273
per person
Mar 7 - Mar 9
found 1 day ago
Roundtrip flight included
Atlanta (ATL) to Houston (IAH)
9/10 Wonderful! (1,003 reviews)
Great stay overall! The room was clean, comfortable, and the staff was super friendly. Loved the location and the amenities — definitely worth it. I’d stay here again!
Reviewed on Jan 20, 2026
Hotel Granduca Houston
The Galleria
Save 100% on your flight
Price was $913, price is now $661 per person
$661
per person
Apr 10 - Apr 13
found 1 day ago
Roundtrip flight included
New York (NYC) to Houston (IAH)
9.2/10 Wonderful! (1,002 reviews)
Everything was perfect and the renovated lobby is beautiful.
Reviewed on Jan 25, 2026
4Bdrm 2Bath 4Beds - Sugarland Richmond
Save 100% on your flight
Price was $1,199, price is now $871 per person
$871
per person
Mar 10 - Mar 15
found 1 day ago
Roundtrip flight included
Baltimore (BWI) to Houston (IAH)
7.8/10 Good! (9 reviews)
Check in was very confusing. I had to contact the people listed in order to get codes to get in house. Some of the furniture is very worn and/or broken. The backyard was kind of a mess. Other than that the property was decent.
Reviewed on Mar 5, 2024
Where to stay in Texas Medical Center
Find the best Texas Medical Center areas and neighborhoods for the activities you enjoy most. Learn more about Texas Medical Center
Downtown Houston
3 out of top 10 points of interest in this area
4.5/5(2,300 area reviews)
Largest central business district in Texas, this area boasts major league sports venues, a vibrant Theater District, and shopping options like GreenStreet. Easily navigate with public transportation options like METRORail and bus lines.
Texas Medical Center Hotel Deals
Blossom Hotel Houston, Curio Collection by Hilton
7118 Bertner Ave Houston TX
Fully refundableReserve now, pay when you stay
$174 nightly
The price is $203 total per night from Feb 8 to Feb 9
$203 total
Feb 8 - Feb 9
Total with taxes and fees
9/10 Wonderful! (3,711 reviews)
I had a great stay overall, and the hotel was very nice and clean. However, there was a lack of urgency when it came to meeting certain requests. I had to call multiple times for extra towels, and no one came, so I eventually had to step into the hallway to ask housekeeping directly. Aside from that, ...
Reviewed on Feb 5, 2026
Hyatt Place Houston Medical Center
7329 FANNIN STREET Building 2 Houston TX
Fully refundableReserve now, pay when you stay
$117 nightly
The price is $137 total per night from Feb 8 to Feb 9
$137 total
Feb 8 - Feb 9
Total with taxes and fees
9/10 Wonderful! (2,304 reviews)
Clean room and staff
Reviewed on Feb 3, 2026
Hilton Houston Plaza/Medical Center
6633 Travis St Houston TX
Fully refundableReserve now, pay when you stay
$83 nightly
The price is $97 total per night from Feb 8 to Feb 9
$97 total
Feb 8 - Feb 9
Total with taxes and fees
8.4/10 Very Good! (1,827 reviews)
Clean room, attentive and friendly staff, good resources
Reviewed on Feb 4, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Discover the most popular places to visit in Texas Medical Center
Texas Children's Hospital
Though Texas Children's Hospital might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here.
MD Anderson Cancer Center
Though MD Anderson Cancer Center might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here.
Harris Health System - Ben Taub General Hospital
Though Harris Health System - Ben Taub General Hospital might be what brings you to town, perhaps you'll have a chance to explore more of Houston while you are here.
Things to do
NASA's Space Center Admission Plus Houston City Tour
$109
per adult
92% of travellers recommend
Houston: Houston Botanic Garden Entry Ticket
$12
per adult
80% of travellers recommend
Astroville Tunnel Tour of Downtown Houston (Air-Conditioned)
$25
per adult
100% of travellers recommend
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- Houston Zoo
- MD Anderson Cancer Center
- Hermann Park
- Rice University
- Reckling Park
- Houston Vacations
- Rice Stadium
- Miller Outdoor Theater
- NRG Stadium
- Visit Astrodome
- James Turrell's Twilight Epiphany Skyscape
- Houston Natural Science Museum
- Houston Museum of Fine Arts
- NRG Park
- Houston Museum District Vacations
- Children's Museum of Houston
- Holocaust Museum Houston
- Cullen Sculpture Garden
- Visit Riverside Terrace
- Buffalo Soldiers National Museum
- Visit Houston Museum District
- Car rentals near Houston
- Car rentals near MD Anderson Cancer Center
- Standard Car Rentals near MD Anderson Cancer Center
- Car rentals near Houston Zoo
- Sportscar Car Rentals near Houston Zoo
- Car rentals near Hermann Park
- Car rentals near Rice University
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- Car rentals near James Turrell's Twilight Epiphany Skyscape
- Car rentals near Houston Museum District
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- Discount Quebec Rental Cars in Houston Museum District
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.