Tzantizotz Nature Reserve is a protected spot where you can see wildlife in their natural surroundings. Learn about the preservation efforts while enjoying the outdoors.

This nature reserve is on the to-do lists of many travelers to Santa Cruz La Laguna. But Tzantizotz Nature Reserve isn't the only drawcard in the area. Panajachel Municipal Market, Multiple Use Area Lake Atitlan Basin, and Church of Saint Peter are some other interesting sights close by.

Plan a trip to see Tzantizotz Nature Reserve

Price found within the past 48 hours. Click for updated prices.

Atitlan Oasis Eco Hotel and Spa Kaalpul

Save 100% on your flight

$458

per person

Jan 25 - Jan 31

found 20 hours ago

Roundtrip non-stop flight included

Boston (BOS) to Guatemala City (GUA)

17.2/10 Exceptional! (73 reviews)

A magical spot! Totally secluded with stunning views of Lake Atitlan. Alexis is extraordinarily kind.

Reviewed on Mar 18, 2025

Aviva Hotel

$765

per person

Jan 25 - Jan 31

found 20 hours ago

Roundtrip non-stop flight included

Boston (BOS) to Guatemala City (GUA)

19.6/10 Exceptional! (14 reviews)

Todo perfecto limpio cómodo cilenciosa para descansar vista impresionante a el Lago pero el camino para llegar no está my bonito

Reviewed on Oct 2, 2025

Kula Maya Boutique Hotel & Spa

Save 100% on your flight

$1,084

per person

Jan 25 - Jan 31

found 20 hours ago

Roundtrip non-stop flight included

Boston (BOS) to Guatemala City (GUA)

19.2/10 Exceptional! (107 reviews)

Stunning views. Beautiful rooms and wonderful staff. 10/10

Reviewed on Nov 24, 2025

Browse tours and tickets to explore Tzantizotz Nature Reserve

Tours & day trips

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Lake Atitlan One Day Tour from Antigua

Free cancellation available

Water activities

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Lake Atitlan Cultural Tour Exploring Mayan Villages

Free cancellation available

Food, drink & nightlife

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From Panajachel: Explore the Maya villages of Lake Atitlan

Free cancellation available

Classes & workshops

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Maya Cooking Class from Panajachel

Free cancellation available

Popular places to visit

Azul Maya Archaeological Museum

Browse a private collection of Maya artifacts, such as jewelry and pottery, amassed by a local man during his travels throughout Guatemala.

Lake Atitlan showing landscape views, a lake or waterhole and a sunset

Lake Atitlán

Mountainous treks, artistic pursuits and scuba diving; the towns, villages and volcanoes that surround this picturesque lake in Guatemala's highlands offer adventure and culture.

Church of Saint Francis

Admire the art and architecture of the old Catholic church in Panajachel that is dedicated to the town’s patron saint.

Panajachel Municipal Market

Experience some of Guatemala’s indigenous traditions as you browse the stalls of this colorful market and shop for handcrafted souvenirs and fresh produce.

Church of Saint Peter

Visit a European-style church that enthralls with its impressive façade. The attractive parkland on its doorstep contains a striking statue of St.Peter.