Title: Upstate South Carolina, SC Inns from $161 | Expedia.com [Upstate South Carolina Travel Guide](https://expedia.com/Upstate-South-Carolina.dx553248635975748552)[Hotels in Upstate South Carolina](https://expedia.com/Upstate-South-Carolina-Hotels.d553248635975748552.Travel-Guide-Hotels)[Vacation Rentals in Upstate South Carolina](https://expedia.com/Upstate-South-Carolina-Vacation-Rentals.d553248635975748552.Travel-Guide-VacationRentals)[Flights to Upstate South Carolina](https://expedia.com/Cheap-Flights-To-Upstate-South-Carolina.d553248635975748552.Travel-Guide-Flights)[Things to do in Upstate South Carolina](https://expedia.com/Things-To-Do-In-Upstate-South-Carolina.d553248635975748552.Travel-Guide-Activities)[Car Rentals in Upstate South Carolina](https://expedia.com/Car-Rentals-In-Upstate-South-Carolina.d553248635975748552.Car-Rental-Guide)[Upstate South Carolina Vacation Packages](https://expedia.com/Upstate-South-Carolina.d553248635975748552.Destination-Travel-Guides) ![](https://images.trvl-media.com/place/6122927/69b8ebaa-53a3-428e-ba53-37ac2de11862.jpg?impolicy=fcrop&w=1200&h=500&q=medium) Photo by Ryan Watts ![](https://images.trvl-media.com/place/6122927/69b8ebaa-53a3-428e-ba53-37ac2de11862.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ## Check prices for these dates Next weekend [Apr 10 - Apr 12](https://www.expedia.com/Hotel-Search?regionId=553248635975748552&startDate=2026-04-10&endDate=2026-04-12&adults=2&lodging=INN&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Apr 17 - Apr 19](https://www.expedia.com/Hotel-Search?regionId=553248635975748552&startDate=2026-04-17&endDate=2026-04-19&adults=2&lodging=INN&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In one month [May 1 - May 3](https://www.expedia.com/Hotel-Search?regionId=553248635975748552&startDate=2026-05-01&endDate=2026-05-03&adults=2&lodging=INN&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two months [May 29 - May 31](https://www.expedia.com/Hotel-Search?regionId=553248635975748552&startDate=2026-05-29&endDate=2026-05-31&adults=2&lodging=INN&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Upstate South Carolina inns ![Exterior](https://images.trvl-media.com/lodging/125000000/124760000/124758500/124758447/2aa156e2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Room, 1 Queen Bed, Non Smoking, Private Bathroom | Interior](https://images.trvl-media.com/lodging/125000000/124760000/124758500/124758447/5f8fcc83.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dining](https://images.trvl-media.com/lodging/125000000/124760000/124758500/124758447/0f095966.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Deluxe Room, 1 King Bed, Non Smoking, Private Bathroom | Interior detail](https://images.trvl-media.com/lodging/125000000/124760000/124758500/124758447/a81d1269.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Osceola Lake Inn [](https://www.expedia.com/Hendersonville-Hotels-Osceola-Lake-Inn.h124758447.Hotel-Information) Hendersonville $143 nightly $161 total Apr 14 - Apr 15 Total with taxes and fees [](https://www.expedia.com/Hendersonville-Hotels-Osceola-Lake-Inn.h124758447.Hotel-Information) ![Dining](https://images.trvl-media.com/lodging/12000000/11910000/11909900/11909862/031514df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Main House Deluxe King 2,3 | Iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/12000000/11910000/11909900/11909862/32b89b66.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/12000000/11910000/11909900/11909862/ac14245d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/12000000/11910000/11909900/11909862/90c9b4c5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Highlander Mountain House [](https://www.expedia.com/Highlands-Hotels-Highlander-Mountain-House.h11909862.Hotel-Information) Downtown Highlands 8.6/10 Excellent (226 reviews) "I liked the atmosphere, design and restaurant dinner. Lunch and breakfast could be better" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kristina $195 nightly $214 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Highlands-Hotels-Highlander-Mountain-House.h11909862.Hotel-Information) ![Outdoor pool](https://images.trvl-media.com/lodging/3000000/2030000/2025000/2024975/cca6f1c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Balcony](https://images.trvl-media.com/lodging/3000000/2030000/2025000/2024975/078d2c1e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/3000000/2030000/2025000/2024975/04514020.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Dinner served](https://images.trvl-media.com/lodging/3000000/2030000/2025000/2024975/60ec5fc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Glen-Ella Springs Hotel & Restaurant [](https://www.expedia.com/Helen-Hotels-Glen-Ella-Springs-Inn.h2024975.Hotel-Information) Clarkesville 9.6/10 Exceptional (105 reviews) "The grounds were nice to enjoy. Very comfortable room. And really good food. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Kelly $206 nightly $236 total Apr 5 - Apr 6 Total with taxes and fees [](https://www.expedia.com/Helen-Hotels-Glen-Ella-Springs-Inn.h2024975.Hotel-Information) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. [View all properties](https://expedia.com/Hotel-Search?startDate=2026-04-17&endDate=2026-04-18®ionId=553248635975748552&adults=2&lodging=INN&sort=RECOMMENDED&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FUpstate-South-Carolina-Inns.d553248635975748552-aaInns.Travel-Guide-Accommodation)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FUpstate-South-Carolina-Inns.d553248635975748552-aaInns.Travel-Guide-Accommodation) ## Top Upstate South Carolina Hotel Reviews ![Comfort Inn Greenville - Haywood Mall](https://images.trvl-media.com/lodging/1000000/30000/25000/24994/840ecd1b_y.jpg) ### Comfort Inn Greenville - Haywood Mall 10/10 Excellent "Nice, quiet stay. Conveniently located." [](https://expedia.com/Greenville-Hotels-Comfort-Inn-Greenville-Haywood-Mall.h24994.Hotel-Information) ![Hyatt Place Greenville Downtown](https://images.trvl-media.com/lodging/28000000/27050000/27043000/27042919/027a8aef_y.jpg) ### Hyatt Place Greenville Downtown 10/10 Excellent "This was a nice stay. The valets were great, and most importantly, when we forgot something in the closet, they were able to track it down and had it for us when we came back to pick it up. " [](https://expedia.com/Greenville-Hotels-Hyatt-Place-GreenvilleDowntown.h27042919.Hotel-Information) ![Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy](https://images.trvl-media.com/lodging/111000000/110490000/110487400/110487306/d7c06df6_y.jpg) ### Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy 10/10 Excellent "Great spot for couples wanting to connect or a solo trip. " [](https://expedia.com/Postcard-Cabins-Lake-Hartwell.h110487306.Hotel-Information) ![Grand Bohemian Lodge Greenville, Autograph Collection](https://images.trvl-media.com/lodging/72000000/71770000/71762700/71762652/6f048029_y.jpg) ### Grand Bohemian Lodge Greenville, Autograph Collection 10/10 Excellent "The property was excellently maintained!" [](https://expedia.com/Greenville-Hotels-Grand-Bohemian-Lodge-Greenville.h71762652.Hotel-Information) ![Best Western Plus Clemson Hotel & Conference Center](https://images.trvl-media.com/lodging/1000000/10000/1400/1370/w3837h2558x3y3-4efd29d6_y.jpg) ### Best Western Plus Clemson Hotel & Conference Center 6/10 Okay "Older building, clean, but you can tell that things are older in the bathroom and guest rooms. The atrium where breakfast was, is nice, modern, must be an update." [](https://expedia.com/Anderson-Hotels-Best-Western-Plus-University-Inn-Conference-Center.h1370.Hotel-Information) ![Homewood Suites by Hilton Greenville Downtown](https://images.trvl-media.com/lodging/30000000/29060000/29050100/29050020/88b33cc2_y.jpg) ### Homewood Suites by Hilton Greenville Downtown 10/10 Excellent "The coffee wasn’t good but everything else was great. Really really nice people. There was a glass coffee cup on a table on the third floor when the elevator door opened the entire time I stayed there which drove me nuts. I couldn’t believe no staff cleaned it up. " [](https://expedia.com/Greenville-Hotels-Homewood-Suites-By-Hilton-Greenville-Downtown.h29050020.Hotel-Information) ![Aloft Greenville Downtown](https://images.trvl-media.com/lodging/12000000/11960000/11959000/11958914/d91c1d51_y.jpg) ### Aloft Greenville Downtown 10/10 Excellent "Everything was amazing dj down stairs was lit definitely will be back" [](https://expedia.com/Greenville-Hotels-Aloft-Greenville-Downtown.h11958914.Hotel-Information) ![Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG](https://images.trvl-media.com/lodging/1000000/10000/1400/1379/605b3e5f_y.jpg) ### Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG 10/10 Excellent "This is an older property, and it shows, but it’s clean, the staff were incredibly helpful and knowledgeable. It’s a great location for proximity to restaurants and highway access. Nice pool area and fitness center. It was a great value for the money." [](https://expedia.com/Greenville-Hotels-Crowne-Plaza-Hotel-Greenville-I-385-Roper-Mtn-Rd.h1379.Hotel-Information) ![Drury Inn & Suites Greenville](https://images.trvl-media.com/lodging/2000000/1540000/1533500/1533439/6d7853ae_y.jpg) ### Drury Inn & Suites Greenville 10/10 Excellent "Everything was awesome i really enjoyed myself " [](https://expedia.com/Greenville-Hotels-Drury-Inn-Suites-Greenville.h1533439.Hotel-Information) ## Find out more about Upstate South Carolina ## Upstate South Carolina Inns information | Number of reviews | 331 | | ----------------- | ------ | | Accommodation | 0 Inns | | Lowest Price | $161 | | Highest Price | $236 | ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - [Cabin Rentals in Woodruff ](https://www.expedia.com/Woodruff-Cabins.d6348219-aaCabins.Travel-Guide-Accommodation) - [Motels in Woodruff ](https://www.expedia.com/Woodruff-Motels.d6348219-aaMotels.Travel-Guide-Accommodation) - [B&B in Woodruff ](https://www.expedia.com/Woodruff-Bed-And-Breakfast.d6348219-aaBedAndBreakfast.Travel-Guide-Accommodation) - 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