Name: La Quinta Inn & Suites by Wyndham Greenville Haywood
Price range: $77 total
Rating: 7.2

Your Upstate South Carolina Vacation

When adventure calls, answer it with a tailor-made vacation package to Upstate South Carolina. Wherever it is you're going and whatever your plans are, prepare to experience a destination with plenty to offer. Start your trip to Upstate South Carolina with a few nights in Greenville visiting popular sights like Falls Park on the Reedy and Bon Secours Wellness Arena. Spartanburg is another city that draws crowds from far and wide. WestGate Mall and Tyger River Park are two of the top places to see in this destination. Find some travel buddies and start packing, because your Upstate South Carolina vacation is just a few clicks away with Expedia.

The Latest Upstate South Carolina vacation packages

Price found within the past 48 hours. Click for updated prices.

Rodeway Inn & Suites near Outlet Mall - Asheville

West Asheville

$411

per person

Dec 1 - Dec 5

found 1 day ago

Roundtrip flight included

New York (NYC) to Asheville (AVL)

7/10 Good! (17 reviews)

Teresa was a great concierge. Recommended excellent local dining options and was friendly with my family.

Reviewed on Aug 3, 2025

Elevation Lofts Hotel

Downtown Asheville

Save 100% on your flight

$3,316

per person

Oct 23 - Oct 27

found 11 hours ago

Roundtrip non-stop flight included

Orlando (MCO) to Asheville (AVL)

9.2/10 Wonderful! (5 reviews)

Beautiful apartment, central location with helpful staff.

Reviewed on Aug 5, 2025

Grand Bohemian Lodge Asheville, Autograph Collection®

Biltmore Village

Save 100% on your flight

$844

per person

Dec 4 - Dec 9

found 10 hours ago

Roundtrip non-stop flight included

New York (JFK) to Asheville (AVL)

9.2/10 Wonderful! (875 reviews)

My husband and I stayed here and wow..what a gorgeous hotel. Our room was very large clean and quiet. We enjoyed the cozy lobby with a cocktail at night and breakfast was very good. We will definitely stay here again! ❤️

Reviewed on Sep 13, 2025

Comfort Suites Outlet Center

West Asheville

$473

per person

Dec 1 - Dec 5

found 1 day ago

Roundtrip flight included

New York (NYC) to Asheville (AVL)

8.8/10 Excellent! (1,010 reviews)

Very clean! Pet friendly....staff very friendly, central location with tons of restraunts within easy walking distance. Huge beautiful outlet mall (Tanger) a quick and easy two minute walk away.

Reviewed on Sep 7, 2025

Holiday Inn Asheville East-Blue Ridge PKWY by IHG

$433

per person

Dec 4 - Dec 9

found 10 hours ago

Roundtrip non-stop flight included

New York (JFK) to Asheville (AVL)

9.2/10 Wonderful! (1,000 reviews)

Pretty good hotel, very well located, friendly staff. Breakfast was pretty average considering that was not included, other than that it was good

Reviewed on Sep 5, 2025

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Where to stay in Upstate South Carolina

Find the best Upstate South Carolina areas and neighborhoods for the activities you enjoy most. Learn more about Upstate South Carolina

Greenville featuring autumn leaves, a garden and a bridge

Greenville Downtown

3 out of top 10 points of interest in this area

5/5(654 area reviews)

The ample dining options and beautiful river views are top of the list for many visitors to Greenville Downtown. A stop by The Peace Center or Bon Secours Wellness Arena might round out your trip.

Discover the most popular places to visit in Upstate South Carolina

Clemson University

Walk around the campus of Clemson University, a top university in Clemson. Experience the area's theater scene or attend a football game.

Falls Park on the Reedy

Falls Park on the Reedy is just one of the places to see in Greenville, so why not enjoy the other things to explore during your travels? Experience the great live music or attend a sporting event in this family-friendly area.

In my opinion this is a must see! Truly a spiritual experience. The drive up the mountain will feel long but it's worth every minute.

Fred W. Symmes Chapel

You can find out about the history of Cleveland when you stop by Fred W. Symmes Chapel. Wander the lakeside and forest in this relaxing area.

What to do in Upstate South Carolina

Epic City Scavenger Hunt in Garden Grove by Operation City Quest

$10

per adult

Just Desserts Tour In Greenville

$95

per adult

Delicious breakfast on a sunny Saturday morning on the terrace

Small-Group Walking Tour in Greenville with Breakfast

$95

per adult

100% of travellers recommend

See all activities in Upstate South Carolina

Upstate South Carolina Hotel Deals

Hilton Greenville

45 W Orchard Park Dr, Greenville, SC

Fully refundableReserve now, pay when you stay

$112 nightly

$124 total

Sep 21 - Sep 22

Total with taxes and fees

8/10 Very Good! (1,000 reviews)

"Great value! Would stay here again"

Reviewed on Sep 8, 2025

Wooded Cottage - 3 Mi to Clemson University

Clemson

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La Quinta Inn & Suites by Wyndham Greenville Haywood

65 W Orchard Park Dr, Greenville, SC

Fully refundableReserve now, pay when you stay

$70 nightly

$77 total

Sep 21 - Sep 22

Total with taxes and fees

7.2/10 Good! (1,044 reviews)

"I love that it was close to many dinning areas and it has a lobby with small tables that are accessible at any time. I had a meeting in the lobby and no one came and interrupted me talking with my colleague which is priceless to me. They also spoke English and Spanish which is a plus in my book."

Reviewed on Sep 9, 2025

See all 2,825 properties in Upstate South Carolina

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.