Upstate South Carolina Vacations from $676

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Your Upstate South Carolina Vacation

When adventure calls, answer it with a tailor-made vacation package to Upstate South Carolina. Wherever it is you're going and whatever your plans are, prepare to experience a destination with plenty to offer. Start your trip to Upstate South Carolina with a few nights in Greenville visiting popular sights like Falls Park on the Reedy and Bon Secours Wellness Arena. Spartanburg is another city that draws crowds from far and wide. WestGate Mall and Tyger River Park are two of the top places to see in this destination. Find some travel buddies and start packing, because your Upstate South Carolina vacation is just a few clicks away with Expedia.

The Latest Upstate South Carolina vacation packages

Price found within the past 48 hours. Click for updated prices.
Hotel Hartness
The Restoration Asheville
Pinners Compound- 4 BR hot tub fire pit
The Radical Asheville, Tapestry Collection by Hilton
The Windsor Boutique Hotel
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Where to stay in Upstate South Carolina

Find the best Upstate South Carolina areas and neighborhoods for the activities you enjoy most. Learn more about Upstate South Carolina

Discover the most popular places to visit in Upstate South Carolina

What to do in Upstate South Carolina

Upstate South Carolina Hotel Deals

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

3.5 out of 5
851 Congaree Rd Greenville SC
Fully refundable
$105 nightly
The price is $116 total per night from Apr 18 to Apr 19
$116 total
Apr 18 - Apr 19
Total with taxes and fees
8.6/10 Excellent! (1,011 reviews)
Great place to stay.

Reviewed on Apr 12, 2026

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
Hilton Greenville

Hilton Greenville

3.5 out of 5
45 W Orchard Park Dr Greenville SC
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $109 total per night from Apr 19 to Apr 20
$109 total
Apr 19 - Apr 20
Total with taxes and fees
8.2/10 Very Good! (1,009 reviews)
Two of the three elevators were broken. They charge for using their parking lot. It's not even near a city. Had to request clean towels.

Reviewed on Apr 13, 2026

Hilton Greenville
Embassy Suites Greenville Golf Resort & Conference Center

Embassy Suites Greenville Golf Resort & Conference Center

3.5 out of 5
670 Verdae Blvd Greenville SC
Fully refundableReserve now, pay when you stay
$137 nightly
The price is $151 total per night from Apr 19 to Apr 20
$151 total
Apr 19 - Apr 20
Total with taxes and fees
9/10 Wonderful! (1,149 reviews)
Staff is friendly and helpful! Clean room. Easy access to airport.

Reviewed on Apr 13, 2026

Embassy Suites Greenville Golf Resort & Conference Center
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Upstate South Carolina Vacation Packages

Upstate South Carolina Essential Information

Language
English
Currency
U.S dollars
Closest Airport
Charlotte-Douglas Intl. Airport (CLT)

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