Upstate South Carolina Vacations from $603
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Your Upstate South Carolina Vacation
When adventure calls, answer it with a tailor-made vacation package to Upstate South Carolina. Wherever it is you're going and whatever your plans are, prepare to experience a destination with plenty to offer. Start your trip to Upstate South Carolina with a few nights in Greenville visiting popular sights like Falls Park on the Reedy and Bon Secours Wellness Arena. Spartanburg is another city that draws crowds from far and wide. WestGate Mall and Tyger River Park are two of the top places to see in this destination. Find some travel buddies and start packing, because your Upstate South Carolina vacation is just a few clicks away with Expedia.
The Latest Upstate South Carolina vacation packages
Price found within the past 48 hours. Click for updated prices.
The Artful Way
River Arts District
Price was $753, price is now $603 per person
$603
per person
Jun 25 - Jun 28
found 1 day ago
Roundtrip non-stop flight included
West Palm Beach (PBI) to Asheville (AVL)
No reviews
Staff was great, room was very nice. Our only complaint was there were only two coffee pods for the coffee maker and no condiments. There were four of us staying in the room, would have been nice to wake up and have a cup of coffee for everyone.
Reviewed on Apr 15, 2026
The Restoration Asheville
Downtown Asheville
Price was $1,375, price is now $887 per person
$887
per person
May 22 - May 25
found 10 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Asheville (AVL)
9.8/10 Exceptional! (1,184 reviews)
First, the staff was very welcoming and friendly for our two day stay. In addition, the area near the hotel is prime for a low key vibe, surrounded by good choices of food and live entertainment.
Reviewed on Apr 14, 2026
Hotel Hartness
Price was $822, price is now $648 per person
$648
per person
Jun 26 - Jun 28
found 20 hours ago
Roundtrip non-stop flight included
Boston (BOS) to Greenville (GSP)
9.8/10 Exceptional! (685 reviews)
I loved everything about Hotel Hartness!!! The staff and everyone was sooo nice! I will definitely be back.
Reviewed on Apr 19, 2026
Zelda Dearest
Downtown Asheville
Price was $1,053, price is now $842 per person
$842
per person
Jun 25 - Jun 28
found 1 day ago
Roundtrip non-stop flight included
West Palm Beach (PBI) to Asheville (AVL)
10/10 Exceptional! (269 reviews)
The downtown location of this hotel is incredible - you can walk to restaurants, shops, and breweries. Parking was easy, the room was TO DIE for, the whole property is incredibly clean, tbe breakfast is delicious, there’s coffee/tea/water all the time, the patio between houses is super nice, the bed was super comfy and the bathroom was amazing. 15/10, literally cannot wait to go back.
Reviewed on Apr 13, 2026
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See all available trips from Columbus to Upstate South Carolina
View all tripsWhere to stay in Upstate South Carolina
Find the best Upstate South Carolina areas and neighborhoods for the activities you enjoy most. Learn more about Upstate South Carolina
Greenville Downtown
2 out of top 10 points of interest in this area
5/5(657 area reviews)
The ample dining options and beautiful river views are top of the list for many visitors to Greenville Downtown. A stop by The Peace Center or Bon Secours Wellness Arena might round out your trip.
Discover the most popular places to visit in Upstate South Carolina
Clemson University
5/5(423 reviews)
Enjoy the collegiate vibe when you visit Clemson University, during your travels in Clemson. Experience the area's theater scene or attend a football game.
Falls Park on the Reedy
4.5/5(594 reviews)
Falls Park on the Reedy is just one of the places to see in Greenville, so why not enjoy the other things to explore during your travels? Experience the acclaimed theater scene or attend a sporting event in this family-friendly area.
Fred W. Symmes Chapel
5/5(12 reviews)
You can find out about the history of Cleveland when you stop by Fred W. Symmes Chapel. Wander the lakeside and forest in this relaxing area.
What to do in Upstate South Carolina
Guided E-Bike Tour in Greenville South Carolina with Brunch
$105
per adult
Upstate South Carolina Hotel Deals
Hilton Greenville
45 W Orchard Park Dr Greenville SC
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $121 total per night from Apr 26 to Apr 27
$121 total
Apr 26 - Apr 27
Total with taxes and fees
8.2/10 Very Good! (1,009 reviews)
No microwave in the room. Toilet seat was broken. No instruction for the TV how to operate the remote to get the channels. Long wait for the elevator and only one elevator in use.
Reviewed on Apr 19, 2026
Embassy Suites Greenville Golf Resort & Conference Center
670 Verdae Blvd Greenville SC
Fully refundableReserve now, pay when you stay
$137 nightly
The price is $151 total per night from Apr 26 to Apr 27
$151 total
Apr 26 - Apr 27
Total with taxes and fees
9/10 Wonderful! (1,161 reviews)
Great front desk, very helpful and the breakfast was good, thanks!
Reviewed on Apr 18, 2026
Hyatt Place Greenville/Haywood
40 W Orchard Park Dr Greenville SC
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $109 total per night from Apr 27 to Apr 28
$109 total
Apr 27 - Apr 28
Total with taxes and fees
7.8/10 Good! (1,011 reviews)
Breakfast service consistently ended 30–45 minutes earlier than the posted closing time, which was frustrating and inconvenient. The hotel also does not provide extra pillows, and any additional sheets or towels require guests to go down to the lobby themselves—even when these items should have been ...
Reviewed on Apr 20, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Upstate South Carolina Vacation Packages
Upstate South Carolina Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | Charlotte-Douglas Intl. Airport (CLT) |
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- Conestee Nature Preserve
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- Visit Mauldin
- Cu Intl. Center for Automotive Research
- Discovery Island Water Park
- Terrace Shopping Center
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- Golden Lanes and Golden Skate
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- Gravitopia Trampoline Arena
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- Mcalister Square
- Old Towne Shopping Center
- 7th Inning Splash Waterpark
- Lakeside Park
- Lewis Plaza Shopping Center
- Runway Park at GMU
- Prisma Health Greenville Memorial Hospital
- Roper Mountain Science Center
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
