Upstate South Carolina Vacation Packages 2026 from $727

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Your Upstate South Carolina Vacation

When adventure calls, answer it with a tailor-made vacation package to Upstate South Carolina. Wherever it is you're going and whatever your plans are, prepare to experience a destination with plenty to offer. Start your trip to Upstate South Carolina with a few nights in Greenville visiting popular sights like Falls Park on the Reedy and Bon Secours Wellness Arena. Spartanburg is another city that draws crowds from far and wide. WestGate Mall and Tyger River Park are two of the top places to see in this destination. Find some travel buddies and start packing, because your Upstate South Carolina vacation is just a few clicks away with Expedia.

The Latest Upstate South Carolina vacation packages

Price found within the past 48 hours. Click for updated prices.

The Restoration Asheville

Downtown Asheville

Save 100% on your flight

$727

per person

Dec 24 - Dec 28

found 1 day ago

Roundtrip flight included

Fort Lauderdale (FLL) to Asheville (AVL)

9.8/10 Exceptional! (1,211 reviews)

Lovely, unique boutique hotel. Many well designed unusual touches such as a library decor and interesting arched doors. Rooms are large and very well appointed. There’s a fun rooftop bar as well as a basement bar with games and two lane bowling alleys. The fun basket picnic basket was very good.

Reviewed on Sep 30, 2026

Elevation Lofts Hotel

Downtown Asheville

Save 100% on your flight

$1,591

per person

Nov 12 - Nov 15

found 1 hour ago

Roundtrip flight included

Chicago (ORD) to Asheville (AVL)

9.6/10 Exceptional! (8 reviews)

Amazing location. Friendly and communicative staff. Clean room!

Reviewed on Jun 7, 2026

The Windsor Boutique Hotel

Downtown Asheville

Save 100% on your flight

$997

per person

Dec 24 - Dec 28

found 23 hours ago

Roundtrip flight included

Fort Lauderdale (FLL) to Asheville (AVL)

9.8/10 Exceptional! (618 reviews)

Excellent, very large rooms, washer/dryer/kitchen separated from bedroom, very friendly and attentive staff, free parking around the corner. Wonderful experience!

Reviewed on Sep 30, 2026

Asher by Avantstay Mountain Escape + Pool/spa

Save 100% on your flight

$2,302

per person

Dec 24 - Dec 28

found 12 hours ago

Roundtrip flight included

Fort Lauderdale (FLL) to Asheville (AVL)

No reviews

Covered Deck + Firepit Black Mountain Retreat Sweetgum by Avantstay

Save 100% on your flight

$1,504

per person

Dec 24 - Dec 28

found 7 hours ago

Roundtrip flight included

Fort Lauderdale (FLL) to Asheville (AVL)

No reviews

Great space for a girls trip. Would recommend putting some window coverings or shades in the back, felt a little exposed.

Reviewed on Sep 29, 2026

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Where to stay in Upstate South Carolina

Find the best Upstate South Carolina areas and neighborhoods for the activities you enjoy most. Learn more about Upstate South Carolina

A pedestrian bridge with colorful lights, surrounded by trees and a distant building.

Greenville Downtown

2 out of top 10 points of interest in this area

The ample dining options and beautiful river views are top of the list for many visitors to Greenville Downtown. A stop by The Peace Center or Bon Secours Wellness Arena might round out your trip.

Nicholtown

If you're spending some time in Nicholtown, Swamp Rabbit Trail and Pleasantburg Shopping Center are top sights worth seeing.

An aerial view of a park with a winding path, trees in autumn colors, and a bridge.

Overbrook Historic District

While Overbrook Historic District might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Bon Secours Wellness Arena and Beattie House.

A cityscape with a mix of modern and historic buildings, a large parking lot, and a highway.

West End

Arts and entertainment thrive in this Greenville neighborhood, with cultural events at the Peace Center and baseball games at Fluor Field at the West End. Don't miss Falls Park on the Reedy and the picturesque Liberty Bridge crossing the river.

Hampton-Pinckney Historic District

Hampton-Pinckney Historic District is well-liked for its historic sites. If you'd like to do some sightseeing in the greater Greenville area, you might plan a trip to The Children’s Museum of the Upstate or The Peace Center.

Stay near popular Upstate South Carolina attractions

A historic building with a clock tower, surrounded by a well-maintained lawn with a paw print design.

Clemson University

9.6/10 (1,439 reviews)

Enjoy the collegiate vibe when you visit Clemson University, during your travels in Clemson. Experience the area's theater scene or attend a football game.

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Falls Park on the Reedy

9.6/10 (2,661 reviews)

Falls Park on the Reedy is just one of the places to see in Greenville, so why not enjoy the other things to explore during your travels? Experience the acclaimed theater scene or attend a sporting event in this family-friendly area.

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A wooden cross with inscriptions, set against a mountainous landscape with a cloudy sky.

Fred W. Symmes Chapel

9.8/10 (29 reviews)

You can find out about the history of Cleveland when you stop by Fred W. Symmes Chapel. Wander the lakeside and forest in this relaxing area.

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Bon Secours Wellness Arena

8.6/10 (1,219 reviews)

Catch an event at Bon Secours Wellness Arena during your trip to Greenville. Stroll along the riverfront or experience the great live music in this family-friendly area.

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Memorial Stadium

9.6/10 (410 reviews)

Catch an event at Memorial Stadium during your trip to Clemson. Experience the area's theater scene or attend a football game.

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BMW Performance Center

9.0/10 (90 reviews)

You can spend an afternoon browsing the exhibits at BMW Performance Center during your travels in Greer. While in this family-friendly area, you can savor the charming coffeehouses.

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Greenville Convention Center

8.4/10 (571 reviews)

Learn about the events happening at Greenville Convention Center during your trip to Greenville. Attend a sporting event or visit the shops in this family-friendly area.

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