Upstate South Carolina Vacation Packages 2026 from $263

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Your Upstate South Carolina Vacation

When adventure calls, answer it with a tailor-made vacation package to Upstate South Carolina. Wherever it is you're going and whatever your plans are, prepare to experience a destination with plenty to offer. Start your trip to Upstate South Carolina with a few nights in Greenville visiting popular sights like Falls Park on the Reedy and Bon Secours Wellness Arena. Spartanburg is another city that draws crowds from far and wide. WestGate Mall and Tyger River Park are two of the top places to see in this destination. Find some travel buddies and start packing, because your Upstate South Carolina vacation is just a few clicks away with Expedia.

The Latest Upstate South Carolina vacation packages

Price found within the past 48 hours. Click for updated prices.

Bon Paul & Sharky's Youth Hostel

West Asheville

Save 100% on your flight

$263

per person

Dec 8 - Dec 12

found 1 hour ago

Roundtrip flight included

Fort Lauderdale (FLL) to Asheville (AVL)

9.4/10 Exceptional! (48 reviews)

The Restoration Asheville

Downtown Asheville

Save 100% on your flight

$752

per person

Jan 7 - Jan 11

found 1 day ago

Roundtrip non-stop flight included

Orlando (MCO) to Asheville (AVL)

9.8/10 Exceptional! (1,216 reviews)

The Highlands at Sugar

Save 100% on your flight

$494

per person

Dec 24 - Dec 27

found 11 hours ago

Roundtrip flight included

Miami (MIA) to Asheville (AVL)

8.2/10 Very Good! (853 reviews)

Amazing view. The room was very spacious and the location was perfect. Cant wait to stay again.

Reviewed on Oct 11, 2026

Covered Deck + Firepit Black Mountain Retreat Sweetgum by Avantstay

Save 100% on your flight

$1,345

per person

Dec 21 - Dec 26

found 1 day ago

Roundtrip flight included

Fort Lauderdale (FLL) to Asheville (AVL)

8/10 Very Good! (1 review)

Great space for a girls trip. Would recommend putting some window coverings or shades in the back, felt a little exposed.

Reviewed on Sep 29, 2026

The Windsor Boutique Hotel

Downtown Asheville

Save 100% on your flight

$1,217

per person

Dec 16 - Dec 21

found 1 day ago

Roundtrip non-stop flight included

Orlando (MCO) to Asheville (AVL)

9.8/10 Exceptional! (619 reviews)

My wife and I loved the separate living room so that we could get up and not disturb each other. It also was wonderful for stopping by and taking a break when walking around town. The property is in a great location as well. The only downside was not being able to park out front easily to unload. We made it work, though and would definitely stay again!

Reviewed on Oct 11, 2026

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Where to stay in Upstate South Carolina

Find the best Upstate South Carolina areas and neighborhoods for the activities you enjoy most. Learn more about Upstate South Carolina

A pedestrian bridge with colorful lights, surrounded by trees and a distant building.

Greenville Downtown

2 out of top 10 points of interest in this area

The ample dining options and beautiful river views are top of the list for many visitors to Greenville Downtown. A stop by The Peace Center or Bon Secours Wellness Arena might round out your trip.

Nicholtown

If you're spending some time in Nicholtown, Swamp Rabbit Trail and Pleasantburg Shopping Center are top sights worth seeing.

An aerial view of a park with a winding path, trees in autumn colors, and a bridge.

Overbrook Historic District

While Overbrook Historic District might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Bon Secours Wellness Arena and Beattie House.

A cityscape with a mix of modern and historic buildings, a large parking lot, and a highway.

West End

Arts and entertainment thrive in this Greenville neighborhood, with cultural events at the Peace Center and baseball games at Fluor Field at the West End. Don't miss Falls Park on the Reedy and the picturesque Liberty Bridge crossing the river.

A cityscape with a mix of modern and historic buildings, a prominent bridge, and a river.

Green Avenue

If you're looking for some top things to see and do in Green Avenue and surrounding area, you can visit Fluor Field at the West End and The Peace Center.

Stay near popular Upstate South Carolina attractions

A historic building with a clock tower, surrounded by a well-maintained lawn with a paw print design.

Clemson University

9.6/10 (1,439 reviews)

Enjoy the collegiate vibe when you visit Clemson University, during your travels in Clemson. Experience the area's theater scene or attend a football game.

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Falls Park on the Reedy

9.6/10 (2,661 reviews)

Falls Park on the Reedy is just one of the places to see in Greenville, so why not enjoy the other things to explore during your travels? Experience the acclaimed theater scene or attend a sporting event in this family-friendly area.

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A wooden cross with inscriptions, set against a mountainous landscape with a cloudy sky.

Fred W. Symmes Chapel

9.8/10 (29 reviews)

You can find out about the history of Cleveland when you stop by Fred W. Symmes Chapel. Wander the lakeside and forest in this relaxing area.

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Bon Secours Wellness Arena

8.6/10 (1,219 reviews)

Catch an event at Bon Secours Wellness Arena during your trip to Greenville. Stroll along the riverfront or experience the great live music in this family-friendly area.

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Memorial Stadium

9.6/10 (410 reviews)

Catch an event at Memorial Stadium during your trip to Clemson. Experience the area's theater scene or attend a football game.

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BMW Performance Center

9.0/10 (90 reviews)

You can spend an afternoon browsing the exhibits at BMW Performance Center during your travels in Greer. While in this family-friendly area, you can savor the charming coffeehouses.

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Greenville Convention Center

8.4/10 (571 reviews)

Learn about the events happening at Greenville Convention Center during your trip to Greenville. Attend a sporting event or visit the shops in this family-friendly area.

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Haywood Mall

8.8/10 (1,681 reviews)

During your trip to Greenville, you can browse for the perfect souvenirs at Haywood Mall. Experience the great live music or attend a sporting event in this family-friendly area.

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What to do in Upstate South Carolina

Spooky & Haunted Paranormal Bar Crawl Downtown Greenville

Greenville Haunted Bar Tour

$28

per adult

100% of travellers recommend

Just Desserts Tour In Greenville

$95

per adult

Gorgeous loop around Swan Lake at Furman University.

Guided E-Bike Tour in Greenville South Carolina with Brunch

$105

per adult

See all activities in Upstate South Carolina

Upstate South Carolina Hotel Deals

Hilton Greenville

45 W Orchard Park Dr Greenville SC

$111 nightly

$122 total

Nov 1 - Nov 2

Total with taxes and fees

Hyatt Place Greenville/Haywood

40 W Orchard Park Dr Greenville SC

Fully refundableReserve now, pay when you stay

$95 nightly

$104 total

Nov 2 - Nov 3

Total with taxes and fees

Embassy Suites Greenville Golf Resort & Conference Center

670 Verdae Blvd Greenville SC

Fully refundableReserve now, pay when you stay

$108 nightly

$120 total

Nov 1 - Nov 2

Total with taxes and fees

9/10 Wonderful! (1,426 reviews)

"A wonderful stay! Clean and very comfortable! We have stayed here several times and it won’t be the last!"

Reviewed on Oct 12, 2026

See all 3,096 properties in Upstate South Carolina

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.