Upstate South Carolina Vacations from $676
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Your Upstate South Carolina Vacation
When adventure calls, answer it with a tailor-made vacation package to Upstate South Carolina. Wherever it is you're going and whatever your plans are, prepare to experience a destination with plenty to offer. Start your trip to Upstate South Carolina with a few nights in Greenville visiting popular sights like Falls Park on the Reedy and Bon Secours Wellness Arena. Spartanburg is another city that draws crowds from far and wide. WestGate Mall and Tyger River Park are two of the top places to see in this destination. Find some travel buddies and start packing, because your Upstate South Carolina vacation is just a few clicks away with Expedia.
The Latest Upstate South Carolina vacation packages
Price found within the past 48 hours. Click for updated prices.
Hotel Hartness
Price was $910, price is now $676 per person
$676
per person
Jun 18 - Jun 21
found 13 hours ago
Roundtrip non-stop flight included
Buffalo (BUF) to Greenville (GSP)
9.8/10 Exceptional! (685 reviews)
Beautiful property. Almost hate to give a great review since it’s a hidden gem that I selfishly want to keep that way.
Reviewed on Apr 13, 2026
The Restoration Asheville
Downtown Asheville
Save 100% on your flight
Price was $1,324, price is now $886 per person
$886
per person
Jun 21 - Jun 26
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Asheville (AVL)
9.8/10 Exceptional! (1,184 reviews)
Great hotel and staff-enjoyed our stay along with the happy hour, roof top lounge, and outdoor seating areas and great location, too.
Reviewed on Apr 13, 2026
The Radical Asheville, Tapestry Collection by Hilton
River Arts District
Price was $924, price is now $677 per person
$677
per person
Jun 21 - Jun 26
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Asheville (AVL)
9.6/10 Exceptional! (527 reviews)
Excellent stay! The hotel staff are friendly and super helpful with recommendations for what to do, see, and eat in Asheville. The hotel itself is chic and artsy with a killer restaurant and a rooftop with gorgeous sunset views.
Reviewed on Apr 14, 2026
The Windsor Boutique Hotel
Downtown Asheville
Save 100% on your flight
Price was $1,480, price is now $1,090 per person
$1,090
per person
Jun 21 - Jun 26
found 1 day ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Asheville (AVL)
9.8/10 Exceptional! (583 reviews)
Rooms are spacious, wonderfully appointed with soft robes and good coffee. Very comfortable beds. The location is perfect, close to shops, spas, breweries, restaurants. Staff is friendly and helpful. Would absolutely stay here again.
Reviewed on Apr 4, 2026
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See all available trips from Columbus to Upstate South Carolina
View all tripsWhere to stay in Upstate South Carolina
Find the best Upstate South Carolina areas and neighborhoods for the activities you enjoy most. Learn more about Upstate South Carolina
Greenville Downtown
2 out of top 10 points of interest in this area
5/5(657 area reviews)
The ample dining options and beautiful river views are top of the list for many visitors to Greenville Downtown. A stop by The Peace Center or Bon Secours Wellness Arena might round out your trip.
Discover the most popular places to visit in Upstate South Carolina
Clemson University
5/5(423 reviews)
Enjoy the collegiate vibe when you visit Clemson University, during your travels in Clemson. Experience the area's theater scene or attend a football game.
Falls Park on the Reedy
4.5/5(594 reviews)
Falls Park on the Reedy is just one of the places to see in Greenville, so why not enjoy the other things to explore during your travels? Experience the acclaimed theater scene or attend a sporting event in this family-friendly area.
Fred W. Symmes Chapel
5/5(12 reviews)
You can find out about the history of Cleveland when you stop by Fred W. Symmes Chapel. Wander the lakeside and forest in this relaxing area.
What to do in Upstate South Carolina
Guided E-Bike Tour in Greenville South Carolina with Brunch
$105
per adult
Upstate South Carolina Hotel Deals
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
851 Congaree Rd Greenville SC
Fully refundable
$105 nightly
The price is $116 total per night from Apr 18 to Apr 19
$116 total
Apr 18 - Apr 19
Total with taxes and fees
8.6/10 Excellent! (1,011 reviews)
Great place to stay.
Reviewed on Apr 12, 2026
Hilton Greenville
45 W Orchard Park Dr Greenville SC
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $109 total per night from Apr 19 to Apr 20
$109 total
Apr 19 - Apr 20
Total with taxes and fees
8.2/10 Very Good! (1,009 reviews)
Two of the three elevators were broken. They charge for using their parking lot. It's not even near a city. Had to request clean towels.
Reviewed on Apr 13, 2026
Embassy Suites Greenville Golf Resort & Conference Center
670 Verdae Blvd Greenville SC
Fully refundableReserve now, pay when you stay
$137 nightly
The price is $151 total per night from Apr 19 to Apr 20
$151 total
Apr 19 - Apr 20
Total with taxes and fees
9/10 Wonderful! (1,149 reviews)
Staff is friendly and helpful! Clean room. Easy access to airport.
Reviewed on Apr 13, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Upstate South Carolina Vacation Packages
Upstate South Carolina Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | Charlotte-Douglas Intl. Airport (CLT) |
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
