Upstate South Carolina Vacations from $734
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Your Upstate South Carolina Vacation
When adventure calls, answer it with a tailor-made vacation package to Upstate South Carolina. Wherever it is you're going and whatever your plans are, prepare to experience a destination with plenty to offer. Start your trip to Upstate South Carolina with a few nights in Greenville visiting popular sights like Falls Park on the Reedy and Bon Secours Wellness Arena. Spartanburg is another city that draws crowds from far and wide. WestGate Mall and Tyger River Park are two of the top places to see in this destination. Find some travel buddies and start packing, because your Upstate South Carolina vacation is just a few clicks away with Expedia.
The Latest Upstate South Carolina vacation packages
Price found within the past 48 hours. Click for updated prices.
Hotel Hartness
Price was $1,044, price is now $734 per person
$734
per person
Jul 6 - Jul 12
found 7 hours ago
Roundtrip flight included
New York (NYC) to Greenville (GSP)
9.8/10 Exceptional! (696 reviews)
Although this is an exceptional property to stay at as far as cleanliness and great scenery, this time around service wasn’t as great as it usually has been, and they’ve taken away the full continental breakfast that was one of the major amenities that this hotel offered. Also the friendliness of the staff just wasn’t there like it always has been.
Reviewed on Apr 20, 2026
The Restoration Asheville
Downtown Asheville
Save 100% on your flight
Price was $1,490, price is now $1,045 per person
$1,045
per person
Jul 1 - Jul 7
found 18 hours ago
Roundtrip flight included
New York (NYC) to Asheville (AVL)
9.8/10 Exceptional! (1,203 reviews)
Everything was great
Reviewed on Apr 24, 2026
Hilton Garden Inn Asheville Downtown
Downtown Asheville
Price was $1,046, price is now $758 per person
$758
per person
Jul 1 - Jul 7
found 18 hours ago
Roundtrip flight included
New York (NYC) to Asheville (AVL)
9.2/10 Wonderful! (920 reviews)
Wonderful staff, clean and spacious rooms, awesome rooftop bar!
Reviewed on Apr 24, 2026
The Windsor Boutique Hotel
Downtown Asheville
Save 100% on your flight
Price was $1,699, price is now $1,256 per person
$1,256
per person
Jul 1 - Jul 7
found 18 hours ago
Roundtrip flight included
New York (NYC) to Asheville (AVL)
9.8/10 Exceptional! (590 reviews)
Rooms are spacious, wonderfully appointed with soft robes and good coffee. Very comfortable beds. The location is perfect, close to shops, spas, breweries, restaurants. Staff is friendly and helpful. Would absolutely stay here again.
Reviewed on Apr 4, 2026
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See all available trips from Columbus to Upstate South Carolina
View all tripsWhere to stay in Upstate South Carolina
Find the best Upstate South Carolina areas and neighborhoods for the activities you enjoy most. Learn more about Upstate South Carolina
Greenville Downtown
2 out of top 10 points of interest in this area
5/5(657 area reviews)
The ample dining options and beautiful river views are top of the list for many visitors to Greenville Downtown. A stop by The Peace Center or Bon Secours Wellness Arena might round out your trip.
Discover the most popular places to visit in Upstate South Carolina
Clemson University
Enjoy the collegiate vibe when you visit Clemson University, during your travels in Clemson. Experience the area's theater scene or attend a football game.
Falls Park on the Reedy
Falls Park on the Reedy is just one of the places to see in Greenville, so why not enjoy the other things to explore during your travels? Experience the acclaimed theater scene or attend a sporting event in this family-friendly area.
Fred W. Symmes Chapel
You can find out about the history of Cleveland when you stop by Fred W. Symmes Chapel. Wander the lakeside and forest in this relaxing area.
What to do in Upstate South Carolina
Guided E-Bike Tour in Greenville South Carolina with Brunch
$105
per adult
Upstate South Carolina Hotel Deals
Hilton Greenville
45 W Orchard Park Dr Greenville SC
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $121 total per night from May 17 to May 18
$121 total
May 17 - May 18
Total with taxes and fees
8.2/10 Very Good! (1,007 reviews)
Pffft
Reviewed on Apr 25, 2026
Embassy Suites Greenville Golf Resort & Conference Center
670 Verdae Blvd Greenville SC
Fully refundableReserve now, pay when you stay
$127 nightly
The price is $139 total per night from May 10 to May 11
$139 total
May 10 - May 11
Total with taxes and fees
9/10 Wonderful! (1,168 reviews)
As soon as we arrived to the room I entered the bathroom and the toilet was clogged so my boyfriend called front desk around 15 minutes later a maintenance guy came to the room and looked at the toilet in master bathroom but he forgot his plunger so he went to get it. 25 minutes later he came back ...
Reviewed on Apr 25, 2026
Hyatt Place Greenville/Haywood
40 W Orchard Park Dr Greenville SC
Fully refundableReserve now, pay when you stay
$85 nightly
The price is $93 total per night from Apr 27 to Apr 28
$93 total
Apr 27 - Apr 28
Total with taxes and fees
7.8/10 Good! (1,003 reviews)
Great hotel and great location. Staff was very friendly and helpful. Only complaint is that the cleaners used Pinesol that didn’t seem to be diluted and the small was very strong. Otherwise, it was great and I would stay here again.
Reviewed on Apr 25, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Upstate South Carolina Vacation Packages
Upstate South Carolina Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | Charlotte-Douglas Intl. Airport (CLT) |
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- Conestee Nature Preserve
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- Visit Mauldin
- Cu Intl. Center for Automotive Research
- Discovery Island Water Park
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- Golden Lanes and Golden Skate
- Rockwood Park
- Frankie's Fun Park
- Gravitopia Trampoline Arena
- Green Forest Park
- Mcalister Square
- Old Towne Shopping Center
- 7th Inning Splash Waterpark
- Lakeside Park
- Lewis Plaza Shopping Center
- Runway Park at GMU
- Prisma Health Greenville Memorial Hospital
- Roper Mountain Science Center
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
