Title: Upstate South Carolina Vacation Packages 2026 from $802 | Expedia.com [Upstate South Carolina Travel Guide](https://expedia.com/Upstate-South-Carolina.dx6057939)[Hotels in Upstate South Carolina](https://expedia.com/Upstate-South-Carolina-Hotels.d6057939.Travel-Guide-Hotels)[Vacation Rentals in Upstate South Carolina](https://expedia.com/Upstate-South-Carolina-Vacation-Rentals.d6057939.Travel-Guide-VacationRentals)[Flights to Upstate South Carolina](https://expedia.com/Cheap-Flights-To-Upstate-South-Carolina.d6057939.Travel-Guide-Flights)[Things to do in Upstate South Carolina](https://expedia.com/Things-To-Do-In-Upstate-South-Carolina.d6057939.Travel-Guide-Activities)[Car Rentals in Upstate South Carolina](https://expedia.com/Car-Rentals-In-Upstate-South-Carolina.d6057939.Car-Rental-Guide) ![](https://images.trvl-media.com/place/144669/e945b35d-16b4-408c-818b-68622e164446.jpg?impolicy=fcrop&w=1200&h=300&q=medium) # Upstate South Carolina Vacations from $802 ## Book a Hotel + Flight or Car together to unlock savings Photo by RVLuckyorWhat - ## Plan, book, travel with confidence - ### Better together Save up to $1,045 when you book a flight and hotel together\* - ### Find the right fit With over 300,000 hotels worldwide, it's easy to create a perfect package - ### Rest easy Plan, book, and manage your trip all in one place ### Your Upstate South Carolina Vacation When adventure calls, answer it with a tailor-made vacation package to Upstate South Carolina. Wherever it is you're going and whatever your plans are, prepare to experience a destination with plenty to offer. Start your trip to Upstate South Carolina with a few nights in [Greenville](https://www.expedia.com/Greenville.d1388.Destination-Travel-Guides) visiting popular sights like Falls Park on the Reedy and Bon Secours Wellness Arena. [Spartanburg](https://www.expedia.com/Spartanburg.d9787.Destination-Travel-Guides) is another city that draws crowds from far and wide. WestGate Mall and Tyger River Park are two of the top places to see in this destination. Find some travel buddies and start packing, because your Upstate South Carolina vacation is just a few clicks away with Expedia. ## The Latest Upstate South Carolina vacation packages Price found within the past 48 hours. Click for updated prices. ![Fairways of the Mountains](https://images.trvl-media.com/lodging/90000000/89220000/89215100/89215089/8c438a0a_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Fairways of the Mountains $802 per person Jun 4 - Jun 11 found 17 hours ago Roundtrip flight included San Antonio (SAT) to Asheville (AVL) 9.2/10 Wonderful! (35 reviews) complete tools from bath room to kitchen. just need to make sure clean the cooking equipment first some of them still have stain. Reviewed on Mar 27, 2026 ![Pinners Compound- 4 BR hot tub fire pit](https://images.trvl-media.com/lodging/96000000/95360000/95353500/95353482/c9f58154_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Pinners Compound- 4 BR hot tub fire pit South Asheville Save 100% on your flight $1,197 per person Jun 4 - Jun 8 found 15 hours ago Roundtrip non-stop flight included Boston (BOS) to Asheville (AVL) No reviews ![Fox Run at Lake Lure](https://images.trvl-media.com/lodging/89000000/88820000/88812000/88811926/96471861_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Fox Run at Lake Lure $886 per person Jun 4 - Jun 11 found 17 hours ago Roundtrip flight included San Antonio (SAT) to Asheville (AVL) 9.2/10 Wonderful! (192 reviews) The unit and location was absolutely beautiful. Tge family really enjoyed the time we spent there. Will be going back soon😃 Reviewed on Mar 23, 2026 ![The Restoration Asheville](https://images.trvl-media.com/lodging/76000000/75610000/75600300/75600240/2af742a7_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### The Restoration Asheville Downtown Asheville Save 100% on your flight $1,009 per person May 15 - May 18 found 1 day ago Roundtrip flight included Miami (MIA) to Asheville (AVL) 9.8/10 Exceptional! (1,156 reviews) Clean room! Accommodating staff! Breakfast at the door! Wine hour from 5-6 with charcuterie. Walking distance to shops and eateries. Reviewed on Apr 1, 2026 ![Mountain Loft Resort](https://images.trvl-media.com/lodging/90000000/89260000/89255200/89255189/f8aab2c7_y.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) ### Mountain Loft Resort $883 per person Jun 4 - Jun 11 found 17 hours ago Roundtrip flight included San Antonio (SAT) to Asheville (AVL) 8.4/10 Very Good! (10 reviews) The Condo was very nice and very clean. It was very quite and peaceful. Reviewed on Dec 11, 2025 Don't see what you're looking for? See all available trips from Columbus to Upstate South Carolina [View all trips](https://expedia.com/go/package/search/FlightHotel/2026-05-03/2026-05-10/?FromAirport=Columbus,%20Ohio,%20United%20States%20of%20America&Destination=GSP&NumRoom=1&NumAdult=2&NumChild=0&paandie=true) ## Where to stay in Upstate South Carolina Find the best Upstate South Carolina areas and neighborhoods for the activities you enjoy most. [Learn more about Upstate South Carolina](https://expedia.com/Upstate-South-Carolina.dx6057939) ![Greenville Downtown](https://images.trvl-media.com/place/1388/cd6e82af-6f0e-4f28-bd90-dc864c25ddac.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Greenville Downtown 2 out of top 10 points of interest in this area 5/5(657 area reviews) The ample dining options and beautiful river views are top of the list for many visitors to Greenville Downtown. A stop by The Peace Center or Bon Secours Wellness Arena might round out your trip. [Find hotel + flight trips in Greenville Downtown](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Greenville%20Downtown&DestID=6348006&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods) ![Default Image](https://images.trvl-media.com/media/content/expus/graphics/deals/TE_Clouds_card_r1.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Nicholtown If you're spending some time in Nicholtown, Pleasantburg Shopping Center and Swamp Rabbit Trail are top sights worth seeing. [Find hotel + flight trips in Nicholtown](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Nicholtown&DestID=944322769370443776&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods) ![Overbrook Historic District](https://images.trvl-media.com/place/6035267/cb556cb0-09f4-48a1-92a0-474aceebaeea.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Overbrook Historic District While Overbrook Historic District might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Bon Secours Wellness Arena and Beattie House. [Find hotel + flight trips in Overbrook Historic District](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Overbrook%20Historic%20District&DestID=944230627130175488&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods) ![Krissy Simmons](https://images.trvl-media.com/place/6348163/68b54b76-2321-4a98-9351-703daf9d97e1.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### West End Arts and entertainment thrive in this Greenville neighborhood, with cultural events at the Peace Center and baseball games at Fluor Field at the West End. Don't miss Falls Park on the Reedy and the picturesque Liberty Bridge crossing the river. [Find hotel + flight trips in West End](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=West%20End&DestID=6348163&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods) ![Default Image](https://images.trvl-media.com/media/content/expus/graphics/deals/TE_Clouds_card_r1.jpg?impolicy=fcrop&w=350&h=192&q=medium) ### Hampton-Pinckney Historic District Hampton-Pinckney Historic District is well-liked for its historic sites. If you'd like to do some sightseeing in the greater Greenville area, you might plan a trip to The Children’s Museum of the Upstate or The Peace Center. [Find hotel + flight trips in Hampton-Pinckney Historic District](https://expedia.com/go/package/search/FlightHotel/?FromAirport=Downtown%20Columbus,%20Columbus,%20Ohio,%20United%20States%20of%20America&Destination=Hampton-Pinckney%20Historic%20District&DestID=6348164&DaysInFuture=30&StayLength=7&rfrr=TG.LP.Dest.PKG.Neighborhoods) ### Discover the most popular places to visit in Upstate South Carolina !["Clemson University is an American public, coeducational, land-grant and sea-grant research university located in Clemson, South Carolina, United States.More clemson images:"](https://images.trvl-media.com/place/6127431/81e51bd8-6dfc-4739-9fb0-b15a1329fa3d.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Clemson University 5/5(423 reviews) Enjoy the collegiate vibe when you visit Clemson University, during your travels in Clemson. Experience the area's theater scene or attend a football game. [](https://expedia.com/Clemson-University-Clemson.d6127431.Vacation-Attraction) ![Fred W. Symmes Chapel](https://images.trvl-media.com/place/553248621532656718/82a12a54-2b7c-457d-b071-556ed8fd587d.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Fred W. Symmes Chapel 5/5(12 reviews) You can find out about the history of Cleveland when you stop by Fred W. Symmes Chapel. Wander the lakeside and forest in this relaxing area. [](https://expedia.com/Fred-W-Symmes-Chapel-Cleveland.d553248621532656718.Vacation-Attraction) ![Falls Park on the Reedy](https://images.trvl-media.com/place/1388/9768cca7-241b-46cc-9044-0389ae1e8a0a.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Falls Park on the Reedy 4.5/5(594 reviews) Falls Park on the Reedy is just one of the places to see in Greenville, so why not enjoy the other things to explore during your travels? Experience the acclaimed theater scene or attend a sporting event in this family-friendly area. [](https://expedia.com/Falls-Park-On-The-Reedy-Greenville-Downtown.d6082697.Vacation-Attraction) ### What to do in Upstate South Carolina ![Spooky & Haunted Paranormal Bar Crawl Downtown Greenville](https://mediaim.expedia.com/localexpert/44967258/bb9d33b6-ba2f-4d38-aa52-533ef9bcfd7e.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Greenville Haunted Bar Tour $35 per adult **100%** of travellers recommend [](https://expedia.com/things-to-do/greenville-haunted-bar-tour.a44967258.activity-details) ![Just Desserts Tour In Greenville](https://mediaim.expedia.com/localexpert/1351196/8e9eb85a-4aa7-4b2f-88cd-57bc5d997f04.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Just Desserts Tour In Greenville $95 per adult [](https://expedia.com/things-to-do/just-desserts-tour-in-greenville.a1351196.activity-details) ![Greenville: Saturday Morning Breakfast Tour](https://mediaim.expedia.com/localexpert/4536544/2424efd7-807a-4b7b-8d92-2a0a78490524.jpg?impolicy=fcrop&w=900&h=506&q=mediumHigh) #### Greenville: Saturday Morning Breakfast Tour $90 per adult [](https://expedia.com/things-to-do/greenville-saturday-morning-breakfast-tour.a4536544.activity-details) [See all activities in Upstate South Carolina](https://expedia.com/things-to-do/search?rid=6057939) ## Upstate South Carolina Hotel Deals ![Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG](https://images.trvl-media.com/lodging/1000000/10000/1400/1379/605b3e5f_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG 851 Congaree Rd Greenville SC Fully refundable $101 nightly $111 total Apr 4 - Apr 5 Total with taxes and fees 8.6/10 Excellent! (1,003 reviews) Spend 2 nights at this hotel was very happy Reviewed on Apr 3, 2026 [](https://expedia.com/Hotel-Search?startDate=4%2F4%2F2026&endDate=4%2F5%2F2026&selected=1379&PinnedHotelID=1379&HadPinnedHotel=true®ionId=6057939) ![Hilton Greenville](https://images.trvl-media.com/lodging/1000000/30000/23200/23172/8017eeff_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Hilton Greenville 45 W Orchard Park Dr Greenville SC Fully refundableReserve now, pay when you stay $99 nightly $109 total Apr 12 - Apr 13 Total with taxes and fees 8.2/10 Very Good! (1,002 reviews) Excellence Reviewed on Apr 3, 2026 [](https://expedia.com/Hotel-Search?startDate=4%2F12%2F2026&endDate=4%2F13%2F2026&selected=23172&PinnedHotelID=23172&HadPinnedHotel=true®ionId=6057939) ![Embassy Suites Greenville Golf Resort & Conference Center](https://images.trvl-media.com/lodging/1000000/10000/3300/3223/b0e15e12_y.jpg?impolicy=resizecrop&rw=340&ch=150) ### Embassy Suites Greenville Golf Resort & Conference Center 670 Verdae Blvd Greenville SC Fully refundableReserve now, pay when you stay $119 nightly $131 total Apr 5 - Apr 6 Total with taxes and fees 9/10 Wonderful! (1,127 reviews) Clean room. Fresh breakfast. Great service! Reviewed on Apr 1, 2026 [](https://expedia.com/Hotel-Search?startDate=4%2F5%2F2026&endDate=4%2F6%2F2026&selected=3223&PinnedHotelID=3223&HadPinnedHotel=true®ionId=6057939) [See all 2,970 properties in Upstate South Carolina](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Package&startDate=4%2F4%2F2026&endDate=4%2F5%2F2026®ionId=6057939) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Find the Best Upstate South Carolina Vacation Packages ## Upstate South Carolina Essential Information | Language | English | | --------------- | ------------------------------------- | | Currency | U.S dollars | | Closest Airport | Charlotte-Douglas Intl. Airport (CLT) | ## More vacations you might like ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/all-inclusive_holidays_US.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) All Inclusive Vacations [](https://expedia.com/lp/theme-vacations/all-inclusive-vacations?rfrr=editorial.All_Inclusive%20Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/10/17/XPC_Beach_Overview_HR_v3.jpg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Beach Vacations [](https://expedia.com/lp/theme-vacations/beach-vacations?rfrr=editorial.Beach_Vacations.click) ![](https://forever.travel-assets.com/flex/flexmanager/images/2022/06/08/Family_holidays_US_3_.jpeg?impolicy=fcrop&w=300&h=300&q=mediumHigh) Kid Friendly Vacations [](https://expedia.com/lp/theme-vacations/kid-friendly-vacations?rfrr=editorial.Kid_Friendly%20Vacations.click) 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