Upstate South Carolina Vacations from $685
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Your Upstate South Carolina Vacation
When adventure calls, answer it with a tailor-made vacation package to Upstate South Carolina. Wherever it is you're going and whatever your plans are, prepare to experience a destination with plenty to offer. Start your trip to Upstate South Carolina with a few nights in Greenville visiting popular sights like Falls Park on the Reedy and Bon Secours Wellness Arena. Spartanburg is another city that draws crowds from far and wide. WestGate Mall and Tyger River Park are two of the top places to see in this destination. Find some travel buddies and start packing, because your Upstate South Carolina vacation is just a few clicks away with Expedia.
The Latest Upstate South Carolina vacation packages
Price found within the past 48 hours. Click for updated prices.
Hilton Garden Inn Asheville Downtown
Downtown Asheville
Price was $940, price is now $685 per person
$685
per person
Jun 11 - Jun 16
found 1 day ago
Roundtrip non-stop flight included
Chicago (CHI) to Asheville (AVL)
9.2/10 Wonderful! (920 reviews)
Wonderful staff, clean and spacious rooms, awesome rooftop bar!
Reviewed on Apr 24, 2026
The Restoration Asheville
Downtown Asheville
Save 100% on your flight
Price was $1,711, price is now $1,168 per person
$1,168
per person
Jun 11 - Jun 16
found 1 day ago
Roundtrip non-stop flight included
Chicago (CHI) to Asheville (AVL)
9.8/10 Exceptional! (1,203 reviews)
Beautiful hotel and room with great amenities. Great location!
Reviewed on Apr 26, 2026
The Windsor Boutique Hotel
Downtown Asheville
Save 100% on your flight
Price was $2,203, price is now $1,522 per person
$1,522
per person
Jun 5 - Jun 12
found 5 hours ago
Roundtrip flight included
Denver (DEN) to Asheville (AVL)
9.8/10 Exceptional! (590 reviews)
Rooms are spacious, wonderfully appointed with soft robes and good coffee. Very comfortable beds. The location is perfect, close to shops, spas, breweries, restaurants. Staff is friendly and helpful. Would absolutely stay here again.
Reviewed on Apr 4, 2026
The Radical Asheville, Tapestry Collection by Hilton
River Arts District
Price was $1,405, price is now $1,033 per person
$1,033
per person
Jun 5 - Jun 12
found 5 hours ago
Roundtrip flight included
Denver (DEN) to Asheville (AVL)
9.6/10 Exceptional! (541 reviews)
Great place to stay in River Arts District of Asheville.
Reviewed on Apr 23, 2026
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See all available trips from Columbus to Upstate South Carolina
View all tripsWhere to stay in Upstate South Carolina
Find the best Upstate South Carolina areas and neighborhoods for the activities you enjoy most. Learn more about Upstate South Carolina
Greenville Downtown
2 out of top 10 points of interest in this area
5/5(657 area reviews)
The ample dining options and beautiful river views are top of the list for many visitors to Greenville Downtown. A stop by The Peace Center or Bon Secours Wellness Arena might round out your trip.
Discover the most popular places to visit in Upstate South Carolina
Clemson University
Enjoy the collegiate vibe when you visit Clemson University, during your travels in Clemson. Experience the area's theater scene or attend a football game.
Falls Park on the Reedy
Falls Park on the Reedy is just one of the places to see in Greenville, so why not enjoy the other things to explore during your travels? Experience the acclaimed theater scene or attend a sporting event in this family-friendly area.
Fred W. Symmes Chapel
You can find out about the history of Cleveland when you stop by Fred W. Symmes Chapel. Wander the lakeside and forest in this relaxing area.
What to do in Upstate South Carolina
Upstate South Carolina Hotel Deals
Hilton Greenville
45 W Orchard Park Dr Greenville SC
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $121 total per night from May 3 to May 4
$121 total
May 3 - May 4
Total with taxes and fees
8.2/10 Very Good! (1,012 reviews)
Room was clean and staff was friendly. Negative areas were: For 3 person occupancy only enough supplies for one coffee. Refrigerator didn’t cool. Onsite restaurant was overpriced.
Reviewed on Apr 28, 2026
Embassy Suites Greenville Golf Resort & Conference Center
670 Verdae Blvd Greenville SC
Fully refundableReserve now, pay when you stay
$110 nightly
The price is $121 total per night from May 17 to May 18
$121 total
May 17 - May 18
Total with taxes and fees
9/10 Wonderful! (1,173 reviews)
Great trip… close to golfing
Reviewed on Apr 27, 2026
Hyatt Place Greenville/Haywood
40 W Orchard Park Dr Greenville SC
Fully refundableReserve now, pay when you stay
$95 nightly
The price is $104 total per night from May 25 to May 26
$104 total
May 25 - May 26
Total with taxes and fees
7.8/10 Good! (1,009 reviews)
Great experience
Reviewed on Apr 28, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Upstate South Carolina Vacation Packages
Upstate South Carolina Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | Charlotte-Douglas Intl. Airport (CLT) |
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- Conestee Nature Preserve
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- Visit Mauldin
- Cu Intl. Center for Automotive Research
- Discovery Island Water Park
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- Gravitopia Trampoline Arena
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- Mcalister Square
- Old Towne Shopping Center
- 7th Inning Splash Waterpark
- Lakeside Park
- Lewis Plaza Shopping Center
- Runway Park at GMU
- Prisma Health Greenville Memorial Hospital
- Roper Mountain Science Center
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
