Upstate South Carolina Vacation Packages 2026 from $911

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Your Upstate South Carolina Vacation

When adventure calls, answer it with a tailor-made vacation package to Upstate South Carolina. Wherever it is you're going and whatever your plans are, prepare to experience a destination with plenty to offer. Start your trip to Upstate South Carolina with a few nights in Greenville visiting popular sights like Falls Park on the Reedy and Bon Secours Wellness Arena. Spartanburg is another city that draws crowds from far and wide. WestGate Mall and Tyger River Park are two of the top places to see in this destination. Find some travel buddies and start packing, because your Upstate South Carolina vacation is just a few clicks away with Expedia.

The Latest Upstate South Carolina vacation packages

Price found within the past 48 hours. Click for updated prices.

Hotel Hartness

Save 100% on your flight

$911

per person

Oct 28 - Nov 4

found 1 day ago

Roundtrip non-stop flight included

Boston (BOS) to Greenville (GSP)

9.8/10 Exceptional! (823 reviews)

Loved the hotel! Immaculate and great service. Easy parking. The only thing I would suggest is having the pool open later than dark. It is lit up and inviting in September but not allowed to swim after dinner basically.

Reviewed on Sep 17, 2026

Backwoods Getaway

Save 100% on your flight

$1,180

per person

Dec 7 - Dec 12

found 1 day ago

Roundtrip non-stop flight included

Orlando (MCO) to Asheville (AVL)

10/10 Exceptional! (1 review)

Wonderful location, beautiful and serene property! Absolutely loved the decor and amenities, felt like we were staying in a treehouse surrounded by deer and other wildlife. Thank you, Woodstock Manor!

Reviewed on Aug 2, 2024

Sky-high Mountain Luxury w Jaw Dropping Views

Save 100% on your flight

$2,933

per person

Nov 17 - Nov 23

found 1 day ago

Roundtrip non-stop flight included

Orlando (MCO) to Asheville (AVL)

No reviews

The Omni Grove Park Inn & Spa

Grove Park- Sunset

Save 100% on your flight

$1,354

per person

Nov 17 - Nov 23

found 1 day ago

Roundtrip non-stop flight included

Orlando (MCO) to Asheville (AVL)

9.2/10 Wonderful! (1,004 reviews)

We had a wonderful stay!!

Reviewed on Sep 16, 2026

Sky-high Luxury w Million Dollar Views

Save 100% on your flight

$2,189

per person

Nov 17 - Nov 23

found 1 day ago

Roundtrip non-stop flight included

Orlando (MCO) to Asheville (AVL)

No reviews

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Where to stay in Upstate South Carolina

Find the best Upstate South Carolina areas and neighborhoods for the activities you enjoy most. Learn more about Upstate South Carolina

A pedestrian bridge with colorful lights, surrounded by trees and a distant building.

Greenville Downtown

2 out of top 10 points of interest in this area

The ample dining options and beautiful river views are top of the list for many visitors to Greenville Downtown. A stop by The Peace Center or Bon Secours Wellness Arena might round out your trip.

Nicholtown

If you're spending some time in Nicholtown, Swamp Rabbit Trail and Pleasantburg Shopping Center are top sights worth seeing.

An aerial view of a park with a winding path, trees in autumn colors, and a bridge.

Overbrook Historic District

While Overbrook Historic District might not have many sights to explore, venturing just a little farther will lead you to top things to see and do like Bon Secours Wellness Arena and Beattie House.

Hampton-Pinckney Historic District

Hampton-Pinckney Historic District is well-liked for its historic sites. If you'd like to do some sightseeing in the greater Greenville area, you might plan a trip to The Children’s Museum of the Upstate or The Peace Center.

A cityscape with a mix of modern and historic buildings, a large parking lot, and a highway.

West End

Arts and entertainment thrive in this Greenville neighborhood, with cultural events at the Peace Center and baseball games at Fluor Field at the West End. Don't miss Falls Park on the Reedy and the picturesque Liberty Bridge crossing the river.

Stay near popular Upstate South Carolina attractions

A historic building with a clock tower, surrounded by a well-maintained lawn with a paw print design.

Clemson University

9.6/10 (1,439 reviews)

Walk around the campus of Clemson University, a top university in Clemson. Experience the area's theater scene or attend a football game.

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Falls Park on the Reedy

9.6/10 (2,661 reviews)

Falls Park on the Reedy is just one of the places to see in Greenville, so why not enjoy the other things to explore during your travels? Experience the acclaimed theater scene or attend a sporting event in this family-friendly area.

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Bon Secours Wellness Arena

8.6/10 (1,219 reviews)

Catch an event at Bon Secours Wellness Arena during your trip to Greenville. Stroll along the riverfront or experience the great live music in this family-friendly area.

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Greenville Convention Center

8.4/10 (571 reviews)

Learn about the events happening at Greenville Convention Center during your trip to Greenville. Attend a sporting event or visit the shops in this family-friendly area.

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Memorial Stadium

9.6/10 (410 reviews)

Catch an event at Memorial Stadium during your trip to Clemson. Experience the area's theater scene or attend a football game.

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BMW Performance Center

9.0/10 (90 reviews)

You can spend an afternoon browsing the exhibits at BMW Performance Center during your travels in Greer. While in this family-friendly area, you can savor the charming coffeehouses.

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Haywood Mall

8.8/10 (1,681 reviews)

During your trip to Greenville, you can browse for the perfect souvenirs at Haywood Mall. Experience the great live music or attend a sporting event in this family-friendly area.

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What to do in Upstate South Carolina

Spooky & Haunted Paranormal Bar Crawl Downtown Greenville

Greenville Haunted Bar Tour

$28

per adult

100% of travellers recommend

Saturday Evening Craft Cocktail Tour

$105

per adult

100% of travellers recommend

Gorgeous loop around Swan Lake at Furman University.

Guided E-Bike Tour in Greenville South Carolina with Brunch

$105

per adult

See all activities in Upstate South Carolina

Upstate South Carolina Hotel Deals

Embassy Suites Greenville Golf Resort & Conference Center

670 Verdae Blvd Greenville SC

Fully refundableReserve now, pay when you stay

$105 nightly

$116 total

Sep 27 - Sep 28

Total with taxes and fees

Hilton Greenville

45 W Orchard Park Dr Greenville SC

Fully refundableReserve now, pay when you stay

$117 nightly

$129 total

Sep 27 - Sep 28

Total with taxes and fees

Hyatt Place Greenville/Haywood

40 W Orchard Park Dr Greenville SC

Fully refundableReserve now, pay when you stay

$89 nightly

$97 total

Sep 28 - Sep 29

Total with taxes and fees

8/10 Very Good! (1,000 reviews)

"The staff was friendly, they are under rennovations which I understand but the cleaniless of the rooms couldd be better and the lightening needs to be better. The elevator was horrible barely worked."

Reviewed on Sep 16, 2026

See all 3,084 properties in Upstate South Carolina

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.