Upstate South Carolina Vacations from $219
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Your Upstate South Carolina Vacation
When adventure calls, answer it with a tailor-made vacation package to Upstate South Carolina. Wherever it is you're going and whatever your plans are, prepare to experience a destination with plenty to offer. Start your trip to Upstate South Carolina with a few nights in Greenville visiting popular sights like Falls Park on the Reedy and Bon Secours Wellness Arena. Spartanburg is another city that draws crowds from far and wide. WestGate Mall and Tyger River Park are two of the top places to see in this destination. Find some travel buddies and start packing, because your Upstate South Carolina vacation is just a few clicks away with Expedia.
The Latest Upstate South Carolina vacation packages
Price found within the past 48 hours. Click for updated prices.
The Restoration Asheville
Downtown Asheville
Price was $876, price is now $614 per person
$614
per person
Jan 15 - Jan 17
found 23 hours ago
Roundtrip flight included
Newark Liberty Intl. Airport (EWR) to Asheville (AVL)
9.8/10 Exceptional! (1,222 reviews)
Beautiful boutique hotel, well curated space, the nicest staff-they drove us to and from places within the city limits, happy hour wine and charcuterie, multiple bars and so much more!
Reviewed on Nov 15, 2026
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View all tripsWhere to stay in Upstate South Carolina
Find the best Upstate South Carolina areas and neighborhoods for the activities you enjoy most. Learn more about Upstate South Carolina
Greenville Downtown
3 out of top 10 points of interest in this area
The ample dining options and beautiful river views are top of the list for many visitors to Greenville Downtown. A stop by The Peace Center or Bon Secours Wellness Arena might round out your trip.
Stay near popular Upstate South Carolina attractions
What to do in Upstate South Carolina
Small-Group Walking Tour in Greenville with Breakfast
$95
per adult
100% of travellers recommend
Guided E-Bike Tour in Greenville South Carolina with Brunch
$105
per adult
Upstate South Carolina Hotel Deals
Best Western Plus Greenville I-385 Inn & Suites
831 Congaree Rd Greenville SC
Fully refundableReserve now, pay when you stay
$75 nightly
The price is $83 total per night from Dec 6 to Dec 7
$83 total
Dec 6 - Dec 7
Total with taxes and fees
9.2/10 Wonderful! (1,617 reviews)
"Would stay there again when in Greenville"
Reviewed on Nov 15, 2026
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
851 Congaree Rd Greenville SC
Fully refundable
$97 nightly
The price is $107 total per night from Nov 23 to Nov 24
$107 total
Nov 23 - Nov 24
Total with taxes and fees
Days Inn by Wyndham Greenville
60 Roper Mountain Rd Greenville SC
Fully refundableReserve now, pay when you stay
$60 nightly
The price is $66 total per night from Dec 1 to Dec 2
$66 total
Dec 1 - Dec 2
Total with taxes and fees
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find the Best Upstate South Carolina Vacation Packages
Upstate South Carolina Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | Charlotte-Douglas Intl. Airport (CLT) |
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
