Find all hotels by Motel 6 in Upstate South Carolina, SC
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Compare rooms and suites by Motel 6 in Upstate South Carolina with rates, reviews, and availability. Most hotels are fully refundable.
Motel 6 Greenville, SC - I-85 Near Downtown
Motel 6 Greenville, SC - I-85 Near Downtown
6.4 out of 10, (224)
The price is $65
$72 total
includes taxes & fees
Jun 19 - Jun 20
The price is $57
$65 total
includes taxes & fees
Jun 19 - Jun 20
Motel 6 Simpsonville, SC - Greenville
Motel 6 Simpsonville, SC - Greenville
7.2 out of 10, Good, (300)
The price is $67
$74 total
includes taxes & fees
Jun 19 - Jun 20
Motel 6 Spartanburg, Sc – Northwest / Business 85
Motel 6 Spartanburg, Sc – Northwest / Business 85
4.0 out of 10, (4)
The price is $63
$70 total
includes taxes & fees
Jun 23 - Jun 24
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Motel 6 Upstate South Carolina Hotel Guide
Some globe-trotters choose hotels based on location, but others book by name. And thanks to Expedia you don’t have to pick. It is why we offer such an expansive range of Motel 6 hotels in Upstate South Carolina, South Carolina. Known for well-appointed rooms and friendly, personalized service, each of the top Motel 6 Upstate South Carolina hotels guarantees an unparalleled level of comfort and quality.
You’ll find best-in-class amenities like clean rooms and quiet atmospheres, and some Upstate South Carolina Motel 6 locations may even offer extra little benefits and discounts for frequent travelers.
Recent reviews of Upstate South Carolina hotelsExpedia verified reviews
5/5 Excellent
Warm room great stay
"Clean and safe. Just had to turn the AC on once we arrived as it was iff in the room and was stuffy. All else was great."
A verified traveler stayed at Comfort Inn Greenville - Haywood Mall
Posted 2 days ago
Upstate South Carolina Hotels by Brand
Hotels in Upstate South Carolina Neighborhoods
- Greenville Downtown Hotels
- West End Hotels
- Hampton-Pinckney Historic District Hotels
- Colonel Elias Earle Historic District Hotels
- Green Avenue Hotels
- Woodside Cotton Mill Village Historic District Hotels
- Payne-Logan Hotels
- Pettigru Street Historic District Hotels
- Serenity Bay Hotels
- Keowee Plantation Hotels
Hotels near popular Upstate South Carolina Attractions
- Hotels near Clemson University
- Hotels near Lake Keowee
- Hotels near Lake Jocassee
- Hotels near Bon Secours Wellness Arena
- Hotels near Falls Park on the Reedy
- Hotels near Prisma Health Greenville Memorial Hospital
- Hotels near Haywood Mall
- Hotels near Greenville Convention Center
- Hotels near Lake Hartwell
- Hotels near The Peace Center
More Hotel Options in Upstate South Carolina
- Business Hotels (144)
- Cheap Hotels (62)
- Family Hotels (155)
- Golf Hotels (95)
- Historic Hotels (76)
- Hotel Wedding Venues (51)
- Hotels & Resorts for Couples (67)
- Hotels on the Lake (65)
- Hotels with Air Conditioning (181)
- Hotels with Balconies (19)
- Hotels with Bars (62)
- Hotels with Connecting Rooms (85)
- Hotels with Free Airport Shuttle (21)
- Hotels with Free Breakfast (132)
- Hotels with Free Parking (157)
- Hotels with Free Wifi (157)
- Hotels with Hot Tubs (27)
- Hotels with Laundry Facilities (125)
- Hotels with Restaurants (164)
- Hotels with Room Service (25)
- Hotels with Suites (29)
- Hotels with a Gym (113)
- Hotels with a Pool (126)
- Hotels with a View (32)
- Hotels with an Indoor Pool (21)
- Hotels with an Outdoor Pool (125)
- Hotels with smoking rooms (21)
- Luxury Hotels (38)
- Non-Smoking Hotels (92)
- Pet-friendly Hotels (85)
- Resorts & Hotels with Spas (26)
- Romantic Hotels (42)
More Accommodation Types in Upstate South Carolina
- Condo Rentals (16,227)
- Vacation Homes (14,555)
- Apartments (3,957)
- Villas (3,234)
- Resorts (1,023)
- Cottages (1,010)
- Aparthotels (193)
- Cabin Rentals (184)
- Motels (161)
- B&B (82)
- Guest Houses (68)
- Farmstay (45)
- RV Parks (35)
- Condo Resorts (14)
- Lodges (13)
- Chalets (8)
- Houseboats (7)
- Inns (4)
- Castles (3)
- Country Houses (1)
- Hostels (1)
Explore more
Explore more hotels
- Hyatt Place Greenville/Downtown
- Embassy Suites Greenville Golf Resort & Conference Center
- Grand Bohemian Lodge Greenville, Autograph Collection
- Drury Inn & Suites Greenville
- Days Inn by Wyndham Anderson
- Homewood Suites by Hilton Greenville Downtown
- Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd, an IHG Hotel
- Hampton Inn & Suites Greenville-Downtown-RiverPlace
- Wingate by Wyndham - Greenville-Airport
- Comfort Suites At WestGate Mall
- Hampton Inn Spartanburg-North I-85
- Best Western Spartanburg Northwest
- Spartanburg Marriott
- Four Points by Sheraton Spartanburg
- Extended Stay America Premier Suites - Greenville - Spartanburg - I-85
- Fairfield Inn & Suites by Marriott Greenville Simpsonville
- Best Western Travelers Rest Greenville
- Comfort Suites Greenville South
- Holiday Inn Express & Suites Greenville Airport, an IHG Hotel
- Quality Inn Simpsonville - Greenville