A baseball field surrounded by residential houses and a modern building.

Find 4 Star Hotels in Anderson, SC from $177

Check availability on Anderson 4 Star Hotels

Tonight
Sep 23 - Sep 24
Tomorrow
Sep 24 - Sep 25
This weekend
Sep 25 - Sep 27
Next weekend
Oct 2 - Oct 4

Our top choices for Anderson 4-star hotels

A multi-level interior with a spiral staircase, wooden railings, and a seating area with tables and chairs.
A spacious restaurant with high ceilings, wooden flooring, and a mix of modern and classic furniture.
A modern bar area with a wooden ceiling, green bar stools, and a bar counter.
A spacious living area with a sofa, ottoman, and chairs, a dining area with a table, and a kitchen in the background.

1. The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson
Clemson
United States
Laurrie
$239 nightly
$265 total
Sep 27 - Sep 28
Total with taxes and fees
The Shepherd Hotel Downtown Clemson
A modern lounge area with a brick accent wall, a fireplace, and comfortable seating.
A modern living room with a sofa, two armchairs, a coffee table, and a potted plant.
A multi-story hotel with a prominent entrance, a parking lot, and a landscaped area with a small tree.
A hotel room with a bed, a sofa, a dining table with chairs, a coffee machine, and a TV mounted on the wall.

2. The Abernathy of Clemson

The Abernathy of Clemson
Clemson
United States
Robert
$159 nightly
$177 total
Oct 11 - Oct 12
Total with taxes and fees
The Abernathy of Clemson
A white, two-story house with a front porch, surrounded by trees and shrubs.
A two-story building with a white exterior, a front door, and a balcony.
A bedroom with two beds, a TV, and a fireplace.
A dining area with round tables, black chairs, and white tablecloths.

3. Liberty Hall Bed and Breakfast

Liberty Hall Bed and Breakfast
Pendleton
United States
Christine
$178 nightly
$198 total
Oct 25 - Oct 26
Total with taxes and fees
Liberty Hall Bed and Breakfast
A wooden gazebo with a roof and a table and chairs inside, surrounded by trees and overlooking a lake.
A modern living room with a sofa, a coffee table, and a fireplace.
A spacious hotel lobby with a bar area, seating arrangements, and large windows offering views.
A modern kitchen with a stainless steel sink, pendant lighting, and a view to a living area with a sofa and a staircase.

4. Tee Times & Lake Days! Luxe Keowee Key Living

Tee Times & Lake Days! Luxe Keowee Key Living
Salem
Tee Times & Lake Days! Luxe Keowee Key Living
A wooden gazebo with a roof, surrounded by trees, overlooking a lake.
A spacious living area with a high ceiling, wooden beams, a grey sofa, a brown leather chair, and a dining table with a plant.
A marina with boats docked, a lifeguard station, and a dock with lounge chairs.
A cozy living room with a fireplace, leather armchair, and a large window.

5. Designer Retreat w/ Pool, Golf + Beach Access!

Designer Retreat w/ Pool, Golf + Beach Access!
Salem
United States
Anonymous traveler
Designer Retreat w/ Pool, Golf + Beach Access!
A lakeside property with a marina, multiple buildings, and surrounding greenery.
A lakeside property with a dock and boats, surrounded by dense forest and a clear view of the lake.

6. Wooded Keowee Key Retreat Near Golf & Trails

Wooded Keowee Key Retreat Near Golf & Trails
Salem
Wooded Keowee Key Retreat Near Golf & Trails
A marina with boats docked, a wooden pier, and a clear sky.
A kitchen with white cabinets, a stainless steel refrigerator, a microwave, and a sink.
A multi-story hotel with a parking lot and a view of a lake.

7. Lake Keowee Condo w/ Balcony & Resort Amenities!

Lake Keowee Condo w/ Balcony & Resort Amenities!
Salem
Lake Keowee Condo w/ Balcony & Resort Amenities!
A swimming pool with a view of the lake and docked boats.
A modern kitchen with a central island, stainless steel appliances, wooden cabinets, and a window providing natural light.
A marina with boats docked, surrounded by greenery and trees.
A spacious living area with a high ceiling, a large window with a view of trees, a kitchen with a bar, and a comfortable seating area with a sofa and ottomans.

8. Keowee Key Condo w/ Lake Access & Community Pools!

Keowee Key Condo w/ Lake Access & Community Pools!
Salem
Keowee Key Condo w/ Lake Access & Community Pools!
A marina with boats docked, a lifeguard station, and a dock with lounge chairs.
A spacious dining area with a wooden table, chairs, and a chandelier. A cozy seating area with a sofa and chairs is visible in the background.
A multi-story hotel with a parking lot and a view of a lake.
An indoor swimming pool with clear lanes, a covered roof, and a bench area.

9. Lake Keowee Condo: Resort Pools & Lake Access!

Lake Keowee Condo: Resort Pools & Lake Access!
Salem
Lake Keowee Condo: Resort Pools & Lake Access!
A gazebo with a wooden roof and open sides, surrounded by trees and overlooking a body of water.
A dining area with a wooden table and chairs, a kitchen with white cabinets, and a staircase with a white railing.
A marina with boats docked, surrounded by greenery and trees.
A swimming pool with a view of a lake and docked boats.

10. Salem Vacation Rental w/ Lake Keowee Access!

Salem Vacation Rental w/ Lake Keowee Access!
Salem
Salem Vacation Rental w/ Lake Keowee Access!
A gazebo with a wooden roof and open sides, surrounded by trees and overlooking a body of water.
A sandy beach with a calm lake surrounded by trees.
A large indoor swimming pool with clear lanes, a covered roof, and seating areas along the sides.
A marina with boats docked, a lifeguard station, and a view of a lake surrounded by trees.

11. Views, Pools & Marina: Lake Keowee Condo!

Views, Pools & Marina: Lake Keowee Condo!
Salem
Views, Pools & Marina: Lake Keowee Condo!
A spacious dining area with a wooden table and chairs, a fireplace, and large windows offering a view of the outdoors.
A modern kitchen with white cabinets, a wooden island, stainless steel appliances, and a tiled floor.
A backyard with a fire pit, four Adirondack chairs, a wooden shed, and a small wooden structure with a smiley face.
A spacious dining area with a wooden table and chairs, a large rug, and a view of the kitchen and outdoor area.

12. Lake Hartwell Frank Howard Home Clemson

Lake Hartwell Frank Howard Home Clemson
Anderson
$273 nightly
$303 total
Oct 4 - Oct 5
Total with taxes and fees
Lake Hartwell Frank Howard Home Clemson
A spacious kitchen with a large island, wooden cabinets, and pendant lighting.
A spacious living area with a large flat-screen TV, a wooden cabinet, a grey sofa set, and a patterned ottoman.
A residential house with a covered porch, a well-maintained lawn, and a clear sky.
A modern kitchen with a central island, bar stools, and pendant lighting.

13. 5 Mi to Memorial Stadium & Beach: Modern Townhome

5 Mi to Memorial Stadium & Beach: Modern Townhome
Central
5 Mi to Memorial Stadium & Beach: Modern Townhome
A spacious living room with a wooden ceiling, large windows, a dining table with chairs, a sofa, and a flat-screen TV.
A marina with boats docked, a pier, and a forested area in the background.
A cozy living room with a sofa, coffee table, and a view of the kitchen.
A bedroom with a sloped ceiling, a bed with a floral bedspread, a dresser, a television, and a window with a view of trees.

14. Keowee Keys Home w/ Mountains View & Lake Access!

Keowee Keys Home w/ Mountains View & Lake Access!
Salem
United States
KURT
Keowee Keys Home w/ Mountains View & Lake Access!
A balcony with a glass table and wicker chairs, overlooking a lake and trees.
A well-lit room with a dining table, chairs, a sofa, and a large window with a view of trees.
A multi-story parking garage with two cars parked.
A lakeside view with boats docked, surrounded by dense trees and a clear sky.

15. Lake Keowee Resort Condo w/ Fantastic View

Lake Keowee Resort Condo w/ Fantastic View
Salem
United States
Tiffany
Lake Keowee Resort Condo w/ Fantastic View
A wooden gazebo with a roof, surrounded by trees, overlooking a lake.
A marina with boats docked, a lifeguard station, and a dock with lounge chairs.
An indoor swimming pool with clear lanes, a covered roof, and blue and white flags.
A sandy beach with a calm lake surrounded by trees.

16. Keowee Key Condo w/ Lake Access!

Keowee Key Condo w/ Lake Access!
Salem
Keowee Key Condo w/ Lake Access!
A spacious room with a pool table, a foosball table, and a red leather couch.
A spacious kitchen with granite countertops, wooden cabinets, a dishwasher, and a large window with blinds.
A covered porch with a sofa and coffee table, surrounded by trees.
A bathroom with a wooden floor, a white toilet, a sink with a soap dispenser, and a mirror with an ornate frame.

17. Clemson Game Day Villa Near Campus & Lakes

Clemson Game Day Villa Near Campus & Lakes
Clemson
Clemson Game Day Villa Near Campus & Lakes
A wooden gazebo with a roof, surrounded by trees, overlooking a lake.
A private beach with a stone pathway leading to the water, surrounded by trees and a wooden fence.
An indoor swimming pool with clear lanes, a covered roof, and blue and white flags.
A marina with boats docked, a lifeguard station, and a dock with lounge chairs.

18. Marina Villa Condo at Lake Keowee w/ Fireplace

Marina Villa Condo at Lake Keowee w/ Fireplace
Salem
Marina Villa Condo at Lake Keowee w/ Fireplace
A covered patio with wooden chairs and a table, overlooking a fenced yard with a body of water and trees.
A spacious living area with a sofa set, a glass coffee table, and a ceiling fan.
A modern kitchen with white cabinets, a stainless steel refrigerator, a microwave, a stove, and a dishwasher.
A two-story house with a dark roof, a garage, and a large rock in the foreground.

19. Lakefront Seneca Vacation Rental w/ Shared Dock!

Lakefront Seneca Vacation Rental w/ Shared Dock!
Seneca
Lakefront Seneca Vacation Rental w/ Shared Dock!
A deck with sun loungers overlooking a lake, a dock, and a forested hillside.
A kitchen with white cabinets, a stainless steel refrigerator, a microwave, a toaster, and a double oven.
A spacious living area with a leather sofa, a patterned rug, and a view through large windows to the outdoors.
A kitchen with a wooden floor, white cabinets, a granite countertop, and a built-in island with stools.

20. 228 Lakeland

228 Lakeland
Anderson
228 Lakeland
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Anderson and related destinations

Downtown's historic district buzzes with local shops and the Electric City Playhouse draws theater lovers from across the region. Lake Hartwell offers prime fishing spots, while the Anderson County Museum reveals fascinating stories about South Carolina's upcountry heritage.

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An aerial view of a forested landscape with a river, a parking lot, and a bridge.

Top Anderson Hotel Reviews

Find out more about Anderson

Anderson Four Star Hotel Information

When you need to book a room with luxurious amazing amenities and the best rates, the 4 star hotels in Anderson, South Carolina are incredible options. Known for their extra perks, first-rate service, and fantastic locations, each of the Anderson 4 star hotels offers the ultimate experience for globe-trotting travelers. Relax in your expertly designed room. Kick back with around-the-clock room service.

Get a good night’s sleep with the ultra-plush bedding, and freshen up in the morning with designer-inspired body products. It’s all available when you stay at one of the top book a four star hotels in Anderson. What’s more, thanks to Expedia you might even score a cheap great deal on a 4 star hotel in Anderson, South Carolina, areas near the hottest attractions, so you can plan a sightseeing adventure and take advantage of unbeatable discounts in one fell swoop.

Whether you’re putting together a serene getaway or want to revel in the most vibrant entertainment district, 4 star Anderson hotels offer everything your heart desires.

Frequently asked questions

How much does it cost to stay in a 4-star hotel in Anderson?
To book a 4-star hotel in Anderson that's within your budget, take advantage of Expedia's handy filter tool. Take a look at the available options during your travel dates and use our pricing filter to set your limit. You can also sort your results by the most wallet-friendly property first.
  • Search for the lowest price from $177
What's the difference between 5-star and 4-star hotels in Anderson?
Offering a friendly traveler experience and upscale surroundings, 4-star hotels are a great option for your Anderson escape. These kinds of stays generally come with loads of handy amenities that make it a breeze to unpack and recharge — think pillowtop mattresses, restaurants and pools. Or get a taste of the high life at a 5-star hotel designed to indulge you in high-end perks and amenities. A personalized service, premium toiletries and gourmet dining are typically included at these swanky retreats.
Does Anderson have any 4-star all-inclusive resorts?
Enjoy a carefree vacation experience where almost everything is included in one upfront price by using our "All inclusive" filter. Staying within budget is a breeze when your room, food and many activities are already taken care of. Eager for more options? Check out the amazing offers on our standard 4-star resorts in and around Anderson.

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