Title: The Best 4 Star Hotels in Anderson, SC from $191 | Expedia.com [Anderson Travel Guide](https://expedia.com/Anderson.dx6058009)[Hotels in Anderson](https://expedia.com/Anderson-Hotels.d6058009.Travel-Guide-Hotels)[Vacation Rentals in Anderson](https://expedia.com/Anderson-Vacation-Rentals.d6058009.Travel-Guide-VacationRentals)[Flights to Anderson](https://expedia.com/Cheap-Flights-To-Anderson.d6058009.Travel-Guide-Flights)[Car Rentals in Anderson](https://expedia.com/Car-Rentals-In-Anderson.d6058009.Car-Rental-Guide)[Anderson Vacation Packages](https://expedia.com/Anderson.d6058009.Destination-Travel-Guides) ![Anderson Bridge](https://images.trvl-media.com/place/6058009/7e18ddb4-746e-4db2-9b84-cb82fafb6645.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6058009/7e18ddb4-746e-4db2-9b84-cb82fafb6645.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Anderson 4 Star Hotels Tonight [Mar 30 - Mar 31](https://www.expedia.com/Hotel-Search?regionId=6058009&startDate=2026-03-30&endDate=2026-03-31&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 31 - Apr 1](https://www.expedia.com/Hotel-Search?regionId=6058009&startDate=2026-03-31&endDate=2026-04-01&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Apr 3 - Apr 5](https://www.expedia.com/Hotel-Search?regionId=6058009&startDate=2026-04-03&endDate=2026-04-05&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Apr 10 - Apr 12](https://www.expedia.com/Hotel-Search?regionId=6058009&startDate=2026-04-10&endDate=2026-04-12&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Anderson 4-star hotels ![Lobby](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/bd45b45c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily full breakfast for a fee](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/5b31fd3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/0de8634b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/db1c155b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Shepherd Hotel Downtown Clemson [](https://www.expedia.com/Clemson-Hotels-The-Shepherd-Hotel-Downtown-Clemson.h87688155.Hotel-Information) Clemson 9.8/10 Exceptional (778 reviews) "Excellent stay, I highly recommend! Accommodations, location, overall vibe, great food and drinks! " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Julie $229 nightly $254 total Apr 8 - Apr 9 Total with taxes and fees [](https://www.expedia.com/Clemson-Hotels-The-Shepherd-Hotel-Downtown-Clemson.h87688155.Hotel-Information) ![Lobby lounge](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/ead974b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Reception](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/a5d6b89e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Custom King Full | In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/179daec9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/8963c3c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Abernathy of Clemson [](https://www.expedia.com/Anderson-Hotels-The-Abernathy-Of-Clemson.h17229377.Hotel-Information) Clemson 9.6/10 Exceptional (582 reviews) "Great staff who demonstrates true southern hospitality. Five minute walk to campus and 10 minutes to downtown - could not be me more convenient. Also cozy bar allowed us to relax after a long day on the road. Nice to see them hiring Clemson students as my daughter who was there for a college tour got some great insights on life at Clemson." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Walter $175 nightly $195 total Apr 14 - Apr 15 Total with taxes and fees [](https://www.expedia.com/Anderson-Hotels-The-Abernathy-Of-Clemson.h17229377.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/84000000/83030000/83025300/83025265/7ccc39b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/84000000/83030000/83025300/83025265/679dc208.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/84000000/83030000/83025300/83025265/286fc023.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family Double Room | Premium bedding, memory foam beds, individually decorated](https://images.trvl-media.com/lodging/84000000/83030000/83025300/83025265/bd9ed0c1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Liberty Hall Bed and Breakfast [](https://www.expedia.com/Pendleton-Hotels-Liberty-Hall-Bed-And-Breakfast.h83025265.Hotel-Information) Pendleton 10/10 Exceptional (86 reviews) "The was by far one of the best bed and breakfast places that I have ever stayed in. The house is beautiful, the rooms and spotless and the breakfast is amazing. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Jennifer Ann $172 nightly $191 total Apr 12 - Apr 13 Total with taxes and fees [](https://www.expedia.com/Pendleton-Hotels-Liberty-Hall-Bed-And-Breakfast.h83025265.Hotel-Information) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/113000000/112470000/112464400/112464340/8d8778c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/113000000/112470000/112464400/112464340/00f3abbe.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/113000000/112470000/112464400/112464340/a549cea5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/113000000/112470000/112464400/112464340/9c4042e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Luxe Keowee Key Living: Golf Views & Resort Pool [](https://www.expedia.com/Salem-Hotels-Golf-Course-View-Modern-Keowee-Key-Condo.h112464340.Hotel-Information) Salem [](https://www.expedia.com/Salem-Hotels-Golf-Course-View-Modern-Keowee-Key-Condo.h112464340.Hotel-Information) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98554500/98554423/6608ac97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98554500/98554423/896f48be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98554500/98554423/642f30df.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98554500/98554423/fea470ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lake Keowee Condo: Resort Pools & Lake Access! [](https://www.expedia.com/Salem-Hotels-Lake-Keowee-Condo-Resort-Pools-Lake-Access.h98554423.Hotel-Information) Salem 10/10 Exceptional (1 review) [](https://www.expedia.com/Salem-Hotels-Lake-Keowee-Condo-Resort-Pools-Lake-Access.h98554423.Hotel-Information) ![Signature House, 4 Bedrooms, Patio | In-room dining](https://images.trvl-media.com/lodging/90000000/89480000/89473800/89473761/157c00b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature House, 4 Bedrooms, Patio | Living room | 43-inch Smart TV with cable channels, TV, fireplace](https://images.trvl-media.com/lodging/90000000/89480000/89473800/89473761/877220d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature House, 4 Bedrooms, Patio | Private kitchen | Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/90000000/89480000/89473800/89473761/f8ba8fcf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/90000000/89480000/89473800/89473761/9a24528f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lake Hartwell Frank Howard Home Clemson [](https://www.expedia.com/Anderson-Hotels-Lake-Hartwell-Frank-Howard-Home-Clemson.h89473761.Hotel-Information) Anderson $273 nightly $303 total Apr 1 - Apr 2 Total with taxes and fees [](https://www.expedia.com/Anderson-Hotels-Lake-Hartwell-Frank-Howard-Home-Clemson.h89473761.Hotel-Information) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/109000000/108450000/108444600/108444520/5525119f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/109000000/108450000/108444600/108444520/d726d506.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/109000000/108450000/108444600/108444520/d3e3f6c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/109000000/108450000/108444600/108444520/f3e42928.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Private Balcony: Lake Keowee Home w/ Pool Access [](https://www.expedia.com/Salem-Hotels-Lake-Keowee-Townhome-W-Marina-Pool-Access.h108444520.Hotel-Information) Salem [](https://www.expedia.com/Salem-Hotels-Lake-Keowee-Townhome-W-Marina-Pool-Access.h108444520.Hotel-Information) ![Family House, 4 Bedrooms, Patio, Courtyard View | Private kitchen | Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/106000000/105560000/105550100/105550047/f91516fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/106000000/105560000/105550100/105550047/c252d911.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family House, 4 Bedrooms, Patio, Courtyard View | View from room](https://images.trvl-media.com/lodging/106000000/105560000/105550100/105550047/769a03d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family House, 4 Bedrooms, Patio, Courtyard View | In-room dining](https://images.trvl-media.com/lodging/106000000/105560000/105550100/105550047/87cae821.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Belvedere [](https://www.expedia.com/Anderson-Hotels-Belvedere.h105550047.Hotel-Information) Anderson 8.0/10 Very Good (1 review) "Bring everything. Including hangers for your clothes, salt and pepper, etc. it is like staying at a place that has one purpose, to rent out. Beds are uncomfortable. Nice big closets with one wire hanger. Why??? " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) CANDACE [](https://www.expedia.com/Anderson-Hotels-Belvedere.h105550047.Hotel-Information) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/95000000/94390000/94382100/94382038/1a03e1b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/95000000/94390000/94382100/94382038/3d5f6f95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/95000000/94390000/94382100/94382038/461e3c7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/95000000/94390000/94382100/94382038/bdf8c3be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Views, Pools & Marina: Lake Keowee Condo! [](https://www.expedia.com/Salem-Hotels-Lake-Keowee-Condo-W-Views-Pools-Marina.h94382038.Hotel-Information) Salem [](https://www.expedia.com/Salem-Hotels-Lake-Keowee-Condo-W-Views-Pools-Marina.h94382038.Hotel-Information) ![Apartment (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/95000000/94960000/94958000/94957904/869da7ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/95000000/94960000/94958000/94957904/ad6d8353.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/95000000/94960000/94958000/94957904/8692c837.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/95000000/94960000/94958000/94957904/5314fa58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Designer Retreat w/ Pool, Golf + Beach Access! [](https://www.expedia.com/Salem-Hotels-Designer-Retreat-W-Pool.h94957904.Hotel-Information) Salem 10/10 Exceptional (1 review) "Property is in a great community, and it was very clean and beautifully decorated." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anonymous traveler [](https://www.expedia.com/Salem-Hotels-Designer-Retreat-W-Pool.h94957904.Hotel-Information) ![Apartment (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/118000000/117500000/117493500/117493483/fa41c5d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/118000000/117500000/117493500/117493483/344f07b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/118000000/117500000/117493500/117493483/be9143a6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/118000000/117500000/117493500/117493483/f1051c24.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 5 Mi to Memorial Stadium & Beach: Modern Townhome [](https://www.expedia.com/Central-Hotels-5-Mi-To-Memorial-Stadium-Beach-Modern-Townhome.h117493483.Hotel-Information) Central [](https://www.expedia.com/Central-Hotels-5-Mi-To-Memorial-Stadium-Beach-Modern-Townhome.h117493483.Hotel-Information) ![Apartment (4 Bedrooms) | Interior](https://images.trvl-media.com/lodging/105000000/104500000/104490400/104490370/4fa0f099.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (4 Bedrooms) | Front of property](https://images.trvl-media.com/lodging/105000000/104500000/104490400/104490370/cd2123cc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (4 Bedrooms) | Interior](https://images.trvl-media.com/lodging/105000000/104500000/104490400/104490370/0653afbd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (4 Bedrooms) | Interior](https://images.trvl-media.com/lodging/105000000/104500000/104490400/104490370/8810e390.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Salem Vacation Rental w/ Lake Keowee Access! [](https://www.expedia.com/Salem-Hotels-Salem-Vacation-Rental-W-Lake-Keowee-Access.h104490370.Hotel-Information) Salem [](https://www.expedia.com/Salem-Hotels-Salem-Vacation-Rental-W-Lake-Keowee-Access.h104490370.Hotel-Information) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537500/93537444/fb4662cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537500/93537444/9f6b4e3e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537500/93537444/0ca3a49b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537500/93537444/9472950c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lake Keowee Resort Condo: Waterfront Balcony [](https://www.expedia.com/Salem-Hotels-Sunny-Lake-Keowee-Condo-W-Waterfront-Balcony.h93537444.Hotel-Information) Salem 10/10 Exceptional (1 review) "Very clean. Amazing amenities. Lake view that takes your breath away." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tiffany [](https://www.expedia.com/Salem-Hotels-Sunny-Lake-Keowee-Condo-W-Waterfront-Balcony.h93537444.Hotel-Information) ![Apartment (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/109000000/108010000/108002400/108002358/d76a95da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/109000000/108010000/108002400/108002358/866bc49d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/109000000/108010000/108002400/108002358/bfd98704.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3 Bedrooms) | Front of property](https://images.trvl-media.com/lodging/109000000/108010000/108002400/108002358/a2b95b3e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Keowee Key Condo w/ Lake Access & Community Pools! [](https://www.expedia.com/Salem-Hotels-Keowee-Key-Condo-W-Lake-Access-Community-Pools.h108002358.Hotel-Information) Salem [](https://www.expedia.com/Salem-Hotels-Keowee-Key-Condo-W-Lake-Access-Community-Pools.h108002358.Hotel-Information) ![Apartment (1 Bedroom) | Front of property](https://images.trvl-media.com/lodging/94000000/93540000/93537200/93537133/9fa693a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537200/93537133/69d5ed43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537200/93537133/6cc9949c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537200/93537133/c224b6bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Keowee Keys Home w/ Mountains View & Lake Access! [](https://www.expedia.com/Salem-Hotels-Gated-Keowee-Keys-Home-W-Mtn-View-Lake-Access.h93537133.Hotel-Information) Salem 8.0/10 Very Good (1 review) "upstairs guestroom has difficult ceiling and space for taller person. Property is in great condition. Wish the queen bed was a king." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) KURT [](https://www.expedia.com/Salem-Hotels-Gated-Keowee-Keys-Home-W-Mtn-View-Lake-Access.h93537133.Hotel-Information) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119670000/119669900/119669823/0840114c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119670000/119669900/119669823/43197a7c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119670000/119669900/119669823/3fc10c5a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119670000/119669900/119669823/5d2078aa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Clemson Game Retreat: Lakefront Keowee Key Condo [](https://www.expedia.com/Salem-Hotels-Clemson-Game-Retreat-Lakefront-Keowee-Key-Condo.h119669823.Hotel-Information) Salem [](https://www.expedia.com/Salem-Hotels-Clemson-Game-Retreat-Lakefront-Keowee-Key-Condo.h119669823.Hotel-Information) ![Apartment (4 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98551500/98551451/5388a21f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (4 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98551500/98551451/db481623.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (4 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98551500/98551451/2ad3fd14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (4 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98551500/98551451/bea2ca6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charming Seneca Home - 3 Mi to Memorial Stadium! [](https://www.expedia.com/Seneca-Hotels-Charming-Seneca-Home-3-Mi-To-Memorial-Stadium.h98551451.Hotel-Information) Seneca [](https://www.expedia.com/Seneca-Hotels-Charming-Seneca-Home-3-Mi-To-Memorial-Stadium.h98551451.Hotel-Information) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/105000000/104100000/104092200/104092180/474920f9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/105000000/104100000/104092200/104092180/922ad3cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/105000000/104100000/104092200/104092180/519b0e3c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/105000000/104100000/104092200/104092180/83bafbb7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lakefront Seneca Vacation Rental w/ Shared Dock! [](https://www.expedia.com/Seneca-Hotels-Lakefront-Seneca-Vacation-Rental-W-Shared-Dock.h104092180.Hotel-Information) Seneca [](https://www.expedia.com/Seneca-Hotels-Lakefront-Seneca-Vacation-Rental-W-Shared-Dock.h104092180.Hotel-Information) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537200/93537195/8729946e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537200/93537195/d42d3679.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537200/93537195/6242630a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537200/93537195/8092f8fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lake Keowee Condo w/ Balcony & Resort Amenities! [](https://www.expedia.com/Salem-Hotels-Lake-Keowee-Condo-W-Balcony-Resort-Amenities.h93537195.Hotel-Information) Salem [](https://www.expedia.com/Salem-Hotels-Lake-Keowee-Condo-W-Balcony-Resort-Amenities.h93537195.Hotel-Information) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/108000000/107270000/107264300/107264271/3104feb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/108000000/107270000/107264300/107264271/80c0fa07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/108000000/107270000/107264300/107264271/3031d180.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/108000000/107270000/107264300/107264271/656632be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Marina Villa Condo at Lake Keowee w/ Fireplace [](https://www.expedia.com/Salem-Hotels-Lakeside-Salem-Condo-W-Balcony-Fireplace.h107264271.Hotel-Information) Salem [](https://www.expedia.com/Salem-Hotels-Lakeside-Salem-Condo-W-Balcony-Fireplace.h107264271.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Anderson-Hotels.s40-0-d6058009.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Anderson-Hotels.s40-0-d6058009.Travel-Guide-Filter-Hotels) ## Anderson and related destinations - Anderson - Columbus - Auburn - Opelika - Altoona - Pullman Downtown's historic district buzzes with local shops and the Electric City Playhouse draws theater lovers from across the region. Lake Hartwell offers prime fishing spots, while the Anderson County Museum reveals fascinating stories about South Carolina's upcountry heritage. [See all hotels in Anderson](https://www.expedia.com/Hotel-Search?startDate=2026-04-13&endDate=2026-04-14&adults=2®ionId=6058009) ![Anderson Bridge](https://images.trvl-media.com/place/6058009/7e18ddb4-746e-4db2-9b84-cb82fafb6645.jpg?impolicy=fcrop&w=900&h=781&p=1&q=high) ## Top Anderson Hotel Reviews ## Find out more about Anderson ## Anderson Four Star Hotel Information When you need to book a room with luxurious amazing amenities and the best rates, the 4 star hotels in Anderson, South Carolina are incredible options. Known for their extra perks, first-rate service, and fantastic locations, each of the Anderson 4 star hotels offers the ultimate experience for globe-trotting travelers. Relax in your expertly designed room. Kick back with around-the-clock room service. Get a good night’s sleep with the ultra-plush bedding, and freshen up in the morning with designer-inspired body products. It’s all available when you stay at one of the top book a four star hotels in Anderson. What’s more, thanks to Expedia you might even score a cheap great deal on a 4 star hotel in Anderson, South Carolina, areas near the hottest attractions, so you can plan a sightseeing adventure and take advantage of unbeatable discounts in one fell swoop. Whether you’re putting together a serene getaway or want to revel in the most vibrant entertainment district, 4 star Anderson hotels offer everything your heart desires. ## Frequently asked questions ### How much does it cost to stay in a 4-star hotel in Anderson? > - Search for the lowest price from $191 ### What's the difference between 5-star and 4-star hotels in Anderson? ### Does Anderson have any 4-star all-inclusive resorts? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Other - [Cabin Rentals in Anderson County ](https://www.expedia.com/Anderson-County-Cabins.d553248635996998401-aaCabins.Travel-Guide-Accommodation) - [Anderson County Hotels ](https://www.expedia.com/Destinations-In-Anderson-County.d553248635996998401.Hotel-Destinations) - [Houseboats in Anderson County ](https://www.expedia.com/Anderson-County-Houseboats.d553248635996998401-aaHouseboats.Travel-Guide-Accommodation) - [Hotels near Anderson County Museum ](https://www.expedia.com/Anderson-County-Museum-Hotels.0-l6308393-0.Travel-Guide-Filter-Hotels) - 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