Title: The Best 4 Star Hotels in Anderson, SC from $169 | Expedia.com [Anderson Travel Guide](https://expedia.com/Anderson.dx6058009)[Hotels in Anderson](https://expedia.com/Anderson-Hotels.d6058009.Travel-Guide-Hotels)[Vacation Rentals in Anderson](https://expedia.com/Anderson-Vacation-Rentals.d6058009.Travel-Guide-VacationRentals)[Flights to Anderson](https://expedia.com/Cheap-Flights-To-Anderson.d6058009.Travel-Guide-Flights)[Car Rentals in Anderson](https://expedia.com/Car-Rentals-In-Anderson.d6058009.Car-Rental-Guide)[Anderson Vacation Packages](https://expedia.com/Anderson.d6058009.Destination-Travel-Guides) ![aerial view of the city](https://images.trvl-media.com/place/6058009/478fa9d4-3485-457a-98cf-34f5ad2bbfc8.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6058009/478fa9d4-3485-457a-98cf-34f5ad2bbfc8.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Anderson 4 Star Hotels Tonight [Feb 16 - Feb 17](https://www.expedia.com/Hotel-Search?regionId=6058009&startDate=2026-02-16&endDate=2026-02-17&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Feb 17 - Feb 18](https://www.expedia.com/Hotel-Search?regionId=6058009&startDate=2026-02-17&endDate=2026-02-18&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Feb 20 - Feb 22](https://www.expedia.com/Hotel-Search?regionId=6058009&startDate=2026-02-20&endDate=2026-02-22&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Feb 27 - Mar 1](https://www.expedia.com/Hotel-Search?regionId=6058009&startDate=2026-02-27&endDate=2026-03-01&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Anderson 4-star hotels ![Lobby](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/bd45b45c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/db1c155b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/0de8634b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/0a5500d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Shepherd Hotel Downtown Clemson [](https://www.expedia.com/Clemson-Hotels-The-Shepherd-Hotel-Downtown-Clemson.h87688155.Hotel-Information) Clemson 9.8/10 Exceptional (762 reviews) "Awesome hotel and very convenient for visiting Clemson." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nina $209 nightly $232 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/Clemson-Hotels-The-Shepherd-Hotel-Downtown-Clemson.h87688155.Hotel-Information) ![Lobby lounge](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/ead974b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Flat-screen TV](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/e914f3bd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property - evening/night](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/8963c3c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Custom King Full | In-room safe, desk, blackout drapes, iron/ironing board](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/179daec9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Abernathy of Clemson [](https://www.expedia.com/Anderson-Hotels-The-Abernathy-Of-Clemson.h17229377.Hotel-Information) Clemson 9.6/10 Exceptional (565 reviews) "Great stay" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Megan $182 nightly $203 total Mar 19 - Mar 20 Total with taxes and fees [](https://www.expedia.com/Anderson-Hotels-The-Abernathy-Of-Clemson.h17229377.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/84000000/83030000/83025300/83025265/7ccc39b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/84000000/83030000/83025300/83025265/679dc208.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/84000000/83030000/83025300/83025265/7b9d65c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/84000000/83030000/83025300/83025265/286fc023.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Liberty Hall Bed and Breakfast [](https://www.expedia.com/Pendleton-Hotels-Liberty-Hall-Bed-And-Breakfast.h83025265.Hotel-Information) Pendleton 10/10 Exceptional (79 reviews) "The owners are amazing. Comfy rooms, stellar breakfast and good people. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Renee $152 nightly $169 total Feb 23 - Feb 24 Total with taxes and fees [](https://www.expedia.com/Pendleton-Hotels-Liberty-Hall-Bed-And-Breakfast.h83025265.Hotel-Information) ![Signature House, 4 Bedrooms, Patio | In-room dining](https://images.trvl-media.com/lodging/90000000/89480000/89473800/89473761/157c00b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature House, 4 Bedrooms, Patio | Living room | 43-inch Smart TV with cable channels, TV, fireplace](https://images.trvl-media.com/lodging/90000000/89480000/89473800/89473761/877220d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature House, 4 Bedrooms, Patio | Private kitchen | Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/90000000/89480000/89473800/89473761/f8ba8fcf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/90000000/89480000/89473800/89473761/9a24528f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lake Hartwell Frank Howard Home Clemson [](https://www.expedia.com/Anderson-Hotels-Lake-Hartwell-Frank-Howard-Home-Clemson.h89473761.Hotel-Information) Anderson [](https://www.expedia.com/Anderson-Hotels-Lake-Hartwell-Frank-Howard-Home-Clemson.h89473761.Hotel-Information) ![Family House, 4 Bedrooms, Patio, Courtyard View | Private kitchen | Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/106000000/105560000/105550100/105550047/f91516fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family House, 4 Bedrooms, Patio, Courtyard View | 4 bedrooms, individually decorated, individually furnished](https://images.trvl-media.com/lodging/106000000/105560000/105550100/105550047/1bcec3cf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family House, 4 Bedrooms, Patio, Courtyard View | In-room dining](https://images.trvl-media.com/lodging/106000000/105560000/105550100/105550047/87cae821.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family House, 4 Bedrooms, Patio, Courtyard View | View from room](https://images.trvl-media.com/lodging/106000000/105560000/105550100/105550047/769a03d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Belvedere [](https://www.expedia.com/Anderson-Hotels-Belvedere.h105550047.Hotel-Information) Anderson 8.0/10 Very Good (1 review) "Bring everything. Including hangers for your clothes, salt and pepper, etc. it is like staying at a place that has one purpose, to rent out. Beds are uncomfortable. Nice big closets with one wire hanger. Why??? " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) CANDACE $418 nightly $464 total Mar 2 - Mar 3 Total with taxes and fees [](https://www.expedia.com/Anderson-Hotels-Belvedere.h105550047.Hotel-Information) ![Dock](https://images.trvl-media.com/lodging/112000000/111440000/111438900/111438806/ed9aaf39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature House, 3 Bedrooms, Kitchen, Lake View | Private kitchen | Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/112000000/111440000/111438900/111438806/1d672e2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature House, 3 Bedrooms, Kitchen, Lake View | Living room | 40-inch Smart TV with cable channels](https://images.trvl-media.com/lodging/112000000/111440000/111438900/111438806/454aaffa.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature House, 3 Bedrooms, Kitchen, Lake View | In-room dining](https://images.trvl-media.com/lodging/112000000/111440000/111438900/111438806/895db893.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 228 Lakeland [](https://www.expedia.com/Anderson-Hotels-228-Lakeland.h111438806.Hotel-Information) Anderson [](https://www.expedia.com/Anderson-Hotels-228-Lakeland.h111438806.Hotel-Information) ![Comfort House, 3 Bedrooms, Non Smoking, Fireplace | Living room | 65-inch Smart TV with cable channels, fireplace, Netflix](https://images.trvl-media.com/lodging/106000000/105580000/105574100/105574095/16c3a46b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/106000000/105580000/105574100/105574095/0ce53e80.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![BBQ/picnic area](https://images.trvl-media.com/lodging/106000000/105580000/105574100/105574095/94645e85.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Comfort House, 3 Bedrooms, Non Smoking, Fireplace | 3 bedrooms, individually decorated, individually furnished](https://images.trvl-media.com/lodging/106000000/105580000/105574100/105574095/d0882306.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Pendleton [](https://www.expedia.com/Pendleton-Hotels-Pendleton.h105574095.Hotel-Information) Pendleton [](https://www.expedia.com/Pendleton-Hotels-Pendleton.h105574095.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/52000000/51670000/51663200/51663188/b97e0a63.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![3 bedrooms, iron/ironing board, WiFi, bed sheets](https://images.trvl-media.com/lodging/52000000/51670000/51663200/51663188/827a2ca9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![TV](https://images.trvl-media.com/lodging/52000000/51670000/51663200/51663188/fa30ae0b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/52000000/51670000/51663200/51663188/e9df570e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Historic Miller's Bungalow [](https://www.expedia.com/Central-Hotels-Historic-Millers-Bungalow.h51663188.Hotel-Information) Central [](https://www.expedia.com/Central-Hotels-Historic-Millers-Bungalow.h51663188.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Anderson-Hotels.s40-0-d6058009.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Anderson-Hotels.s40-0-d6058009.Travel-Guide-Filter-Hotels) ## Anderson and related destinations - Anderson - Columbus - Auburn - Opelika - Altoona - Pullman Downtown's historic district buzzes with local shops and the Electric City Playhouse draws theater lovers from across the region. Lake Hartwell offers prime fishing spots, while the Anderson County Museum reveals fascinating stories about South Carolina's upcountry heritage. [See all hotels in Anderson](https://www.expedia.com/Hotel-Search?startDate=2026-03-02&endDate=2026-03-03&adults=2®ionId=6058009) ![aerial view of the city](https://images.trvl-media.com/place/6058009/478fa9d4-3485-457a-98cf-34f5ad2bbfc8.jpg?impolicy=fcrop&w=900&h=505&p=1&q=high) ## Top Anderson Hotel Reviews ## Find out more about Anderson ## Anderson Four Star Hotel Information When you need to book a room with luxurious amazing amenities and the best rates, the 4 star hotels in Anderson, South Carolina are incredible options. Known for their extra perks, first-rate service, and fantastic locations, each of the Anderson 4 star hotels offers the ultimate experience for globe-trotting travelers. Relax in your expertly designed room. Kick back with around-the-clock room service. Get a good night’s sleep with the ultra-plush bedding, and freshen up in the morning with designer-inspired body products. It’s all available when you stay at one of the top book a four star hotels in Anderson. What’s more, thanks to Expedia you might even score a cheap great deal on a 4 star hotel in Anderson, South Carolina, areas near the hottest attractions, so you can plan a sightseeing adventure and take advantage of unbeatable discounts in one fell swoop. Whether you’re putting together a serene getaway or want to revel in the most vibrant entertainment district, 4 star Anderson hotels offer everything your heart desires. ## Frequently asked questions ### How much does it cost to stay in a 4-star hotel in Anderson? > - Search for the lowest price from $169 ### What's the difference between 5-star and 4-star hotels in Anderson? ### Does Anderson have any 4-star all-inclusive resorts? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Other - [Cabin Rentals in Anderson County ](https://www.expedia.com/Anderson-County-Cabins.d553248635996998401-aaCabins.Travel-Guide-Accommodation) - [Anderson County Hotels ](https://www.expedia.com/Destinations-In-Anderson-County.d553248635996998401.Hotel-Destinations) - [Houseboats in Anderson County ](https://www.expedia.com/Anderson-County-Houseboats.d553248635996998401-aaHouseboats.Travel-Guide-Accommodation) - [Hotels near Anderson County Museum ](https://www.expedia.com/Anderson-County-Museum-Hotels.0-l6308393-0.Travel-Guide-Filter-Hotels) - 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[Apartments in Northlake ](https://www.expedia.com/Northlake-Apartments.d6348002-aaApartments.Travel-Guide-Accommodation) - [Pet-friendly Hotels in Northlake ](https://www.expedia.com/Northlake-Hotels-Pet-Friendly-Hotel.0-0-d6348002-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Hotels near NewSpring Church ](https://www.expedia.com/NewSpring-Church-Hotels.0-l553248621532656690-0.Travel-Guide-Filter-Hotels) - [Hotels with Kitchenettes in Welcome ](https://www.expedia.com/Welcome-Hotels-Hotels-With-Kitchens.0-0-d3000353249-tHotelswithKitchens.Travel-Guide-Filter-Hotels) - [Pet-friendly Hotels in Welcome ](https://www.expedia.com/Welcome-Hotels-Pet-Friendly-Hotel.0-0-d3000353249-tPetfriendlyHotel.Travel-Guide-Filter-Hotels) - [Cheap Hotels in Welcome ](https://www.expedia.com/Welcome-Hotels-Cheap-Hotels.0-0-d3000353249-tCheapHotels.Travel-Guide-Filter-Hotels) - [Cabin Rentals in Welcome ](https://www.expedia.com/Welcome-Cabins.d3000353249-aaCabins.Travel-Guide-Accommodation) - [Flights from Charleston (CHS) to Anderson (AND) ](https://www.expedia.com/lp/flights/chs/and/charleston-to-anderson) - [Flights from Atlanta (ATL) to Anderson (AND) ](https://www.expedia.com/lp/flights/atl/and/atlanta-to-anderson) - [Flights from Charlotte (CLT) to Anderson (AND) ](https://www.expedia.com/lp/flights/clt/and/charlotte-to-anderson) - [Flights from Houston (IAH) to Anderson (AND) ](https://www.expedia.com/lp/flights/iah/and/houston-to-anderson) - [Flights from Raleigh (RDU) to Anderson (AND) ](https://www.expedia.com/lp/flights/rdu/and/raleigh-to-anderson) - [Flights from Nashville (BNA) to Anderson (AND) ](https://www.expedia.com/lp/flights/bna/and/nashville-to-anderson) - [Flights from Greenville (GMU) to Anderson (AND) ](https://www.expedia.com/lp/flights/gmu/and/greenville-to-anderson) - [Flights from Pittsburgh (PIT) to Anderson (AND) ](https://www.expedia.com/lp/flights/pit/and/pittsburgh-to-anderson) - [Flights from Chicago (ORD) to Anderson (AND) ](https://www.expedia.com/lp/flights/ord/and/chicago-to-anderson) - [Flights from Orlando (MCO) to Anderson (AND) ](https://www.expedia.com/lp/flights/mco/and/orlando-to-anderson) - [Flights from Boston (BOS) to Anderson (AND) ](https://www.expedia.com/lp/flights/bos/and/boston-to-anderson) - [Flights from Jacksonville (JAX) to Anderson (AND) ](https://www.expedia.com/lp/flights/jax/and/jacksonville-to-anderson) - [Flights from Tampa (TPA) to Anderson (AND) ](https://www.expedia.com/lp/flights/tpa/and/tampa-to-anderson) - [Flights from Detroit (DTW) to Anderson (AND) ](https://www.expedia.com/lp/flights/dtw/and/detroit-to-anderson) - [Flights from Los Angeles (LAX) to Anderson (AND) ](https://www.expedia.com/lp/flights/lax/and/los-angeles-to-anderson) - [Flights from Phoenix (PHX) to Anderson (AND) ](https://www.expedia.com/lp/flights/phx/and/phoenix-to-anderson) - [Flights from Dallas (DFW) to Anderson (AND) ](https://www.expedia.com/lp/flights/dfw/and/dallas-to-anderson) - [Flights from Cleveland (CLE) to Anderson (AND) ](https://www.expedia.com/lp/flights/cle/and/cleveland-to-anderson) - [Flights from Fort Lauderdale (FLL) to Anderson (AND) ](https://www.expedia.com/lp/flights/fll/and/fort-lauderdale-to-anderson) - [Flights from New York (LGA) to Anderson (AND) ](https://www.expedia.com/lp/flights/lga/and/new-york-to-anderson) - [Flights from San Francisco (SFO) to Anderson (AND) ](https://www.expedia.com/lp/flights/sfo/and/san-francisco-to-anderson) - [Flights from Miami (MIA) to Anderson (AND) ](https://www.expedia.com/lp/flights/mia/and/miami-to-anderson) - [Flights from Grand Rapids (GRR) to Anderson (AND) ](https://www.expedia.com/lp/flights/grr/and/grand-rapids-to-anderson) - [Flights from Seattle (SEA) to Anderson (AND) ](https://www.expedia.com/lp/flights/sea/and/seattle-to-anderson) - [Flights from Anderson County Regional ](https://www.expedia.com/lp/airports/and/flights-from-anderson-county-regional-airport) - [Flights from Syracuse (SYR) to Anderson (AND) ](https://www.expedia.com/lp/flights/syr/and/syracuse-to-anderson) - [Flights from Mobile (MOB) to Anderson (AND) ](https://www.expedia.com/lp/flights/mob/and/mobile-to-anderson) - [Flights from Kansas City (MCI) to Anderson (AND) ](https://www.expedia.com/lp/flights/mci/and/kansas-city-to-anderson) - 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[Flights from El Paso (ELP) to Anderson (AND) ](https://www.expedia.com/lp/flights/elp/and/el-paso-to-anderson) - [Flights from Cincinnati (LUK) to Anderson (AND) ](https://www.expedia.com/lp/flights/luk/and/cincinnati-to-anderson) - [Flights from New York (JFK) to Anderson (AND) ](https://www.expedia.com/lp/flights/jfk/and/new-york-to-anderson) - [Flights from New Orleans (MSY) to Anderson (AND) ](https://www.expedia.com/lp/flights/msy/and/new-orleans-to-anderson) - [Flights from Clearwater (CLW) to Anderson (AND) ](https://www.expedia.com/lp/flights/clw/and/clearwater-to-anderson) - [Flights from Wichita (ICT) to Anderson (AND) ](https://www.expedia.com/lp/flights/ict/and/wichita-to-anderson) - [Flights from Winnipeg (YWG) to Anderson (AND) ](https://www.expedia.com/lp/flights/ywg/and/winnipeg-to-anderson) - [Flights from Baton Rouge (BTR) to Anderson (AND) ](https://www.expedia.com/lp/flights/btr/and/baton-rouge-to-anderson) - [Flights to Anderson County Regional ](https://www.expedia.com/Cheap-Flights-To-Anderson-County-Regional.d6026161.Travel-Guide-Flights) - 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