Title: The Best 4 Star Hotels in Clemson, SC from $210 | Expedia.com [Clemson Travel Guide](https://expedia.com/Clemson.dx6594)[Hotels in Clemson](https://expedia.com/Clemson-Hotels.d6594.Travel-Guide-Hotels)[Vacation Rentals in Clemson](https://expedia.com/Clemson-Vacation-Rentals.d6594.Travel-Guide-VacationRentals)[Flights to Clemson](https://expedia.com/Cheap-Flights-To-Clemson.d6594.Travel-Guide-Flights)[Car Rentals in Clemson](https://expedia.com/Car-Rentals-In-Clemson.d6594.Car-Rental-Guide)[Clemson Vacation Packages](https://expedia.com/Clemson.d6594.Destination-Travel-Guides) ![Sunset on the Docks in Clemson, South Carolina; Shutterstock ID 1068665087; purchase_order: SP-1269 HA 2018 Batch 1; Order: ; client: ; other:](https://images.trvl-media.com/place/6594/3559af33-8fc4-4b07-8fe6-f8db466d3d41.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/6594/3559af33-8fc4-4b07-8fe6-f8db466d3d41.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Clemson 4 Star Hotels Tonight [Mar 4 - Mar 5](https://www.expedia.com/Hotel-Search?regionId=6594&startDate=2026-03-04&endDate=2026-03-05&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 5 - Mar 6](https://www.expedia.com/Hotel-Search?regionId=6594&startDate=2026-03-05&endDate=2026-03-06&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Mar 6 - Mar 8](https://www.expedia.com/Hotel-Search?regionId=6594&startDate=2026-03-06&endDate=2026-03-08&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Mar 13 - Mar 15](https://www.expedia.com/Hotel-Search?regionId=6594&startDate=2026-03-13&endDate=2026-03-15&adults=2&star=40&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Clemson 4-star hotels ![Lobby](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/bd45b45c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Bar (on property)](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/db1c155b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Daily full breakfast for a fee](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/5b31fd3f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Lobby sitting area](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/0a5500d1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### The Shepherd Hotel Downtown Clemson [](https://www.expedia.com/Clemson-Hotels-The-Shepherd-Hotel-Downtown-Clemson.h87688155.Hotel-Information) Clemson 9.8/10 Exceptional (763 reviews) "Awesome hotel and very convenient for visiting Clemson." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Nina $219 nightly $243 total Mar 15 - Mar 16 Total with taxes and fees [](https://www.expedia.com/Clemson-Hotels-The-Shepherd-Hotel-Downtown-Clemson.h87688155.Hotel-Information) ![Front of property](https://images.trvl-media.com/lodging/84000000/83030000/83025300/83025265/7ccc39b2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Restaurant](https://images.trvl-media.com/lodging/84000000/83030000/83025300/83025265/286fc023.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Hallway](https://images.trvl-media.com/lodging/84000000/83030000/83025300/83025265/679dc208.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/84000000/83030000/83025300/83025265/7b9d65c4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Liberty Hall Bed and Breakfast [](https://www.expedia.com/Pendleton-Hotels-Liberty-Hall-Bed-And-Breakfast.h83025265.Hotel-Information) Pendleton 10/10 Exceptional (83 reviews) "The owners are amazing. Comfy rooms, stellar breakfast and good people. " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Renee $190 nightly $210 total Mar 7 - Mar 8 Total with taxes and fees [](https://www.expedia.com/Pendleton-Hotels-Liberty-Hall-Bed-And-Breakfast.h83025265.Hotel-Information) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98554500/98554423/6608ac97.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98554500/98554423/fea470ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98554500/98554423/580b23a5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98554500/98554423/896f48be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lake Keowee Condo: Resort Pools & Lake Access! [](https://www.expedia.com/Salem-Hotels-Lake-Keowee-Condo-Resort-Pools-Lake-Access.h98554423.Hotel-Information) Salem 10/10 Exceptional (1 review) [](https://www.expedia.com/Salem-Hotels-Lake-Keowee-Condo-Resort-Pools-Lake-Access.h98554423.Hotel-Information) ![House, Multiple Beds, Patio, Garden View (Southern Sunshine Retreat) | Interior](https://images.trvl-media.com/lodging/112000000/111650000/111649000/111648957/0dab2c45.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House, Multiple Beds, Patio, Garden View (Southern Sunshine Retreat) | Dining](https://images.trvl-media.com/lodging/112000000/111650000/111649000/111648957/d130503a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![House, Multiple Beds, Patio, Garden View (Southern Sunshine Retreat) | Private kitchen | Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/112000000/111650000/111649000/111648957/cd2b74b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Terrace/patio](https://images.trvl-media.com/lodging/112000000/111650000/111649000/111648957/a2d472c7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Southern Sunshine Retreat [](https://www.expedia.com/Easley-Hotels-Southern-Sunshine-Retreat.h111648957.Hotel-Information) Easley [](https://www.expedia.com/Easley-Hotels-Southern-Sunshine-Retreat.h111648957.Hotel-Information) ![Apartment (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/95000000/94960000/94958000/94957904/869da7ec.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/95000000/94960000/94958000/94957904/456ccd98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/95000000/94960000/94958000/94957904/65c7b260.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/95000000/94960000/94958000/94957904/5314fa58.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Designer Retreat w/ Pool, Golf + Beach Access! [](https://www.expedia.com/Salem-Hotels-Designer-Retreat-W-Pool.h94957904.Hotel-Information) Salem 10/10 Exceptional (1 review) "Property is in a great community, and it was very clean and beautifully decorated." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Anonymous traveler [](https://www.expedia.com/Salem-Hotels-Designer-Retreat-W-Pool.h94957904.Hotel-Information) ![Signature House, 4 Bedrooms, Patio | In-room dining](https://images.trvl-media.com/lodging/90000000/89480000/89473800/89473761/157c00b0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/90000000/89480000/89473800/89473761/9a24528f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature House, 4 Bedrooms, Patio | Living room | 43-inch Smart TV with cable channels, TV, fireplace](https://images.trvl-media.com/lodging/90000000/89480000/89473800/89473761/877220d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/90000000/89480000/89473800/89473761/63caaad7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lake Hartwell Frank Howard Home Clemson [](https://www.expedia.com/Anderson-Hotels-Lake-Hartwell-Frank-Howard-Home-Clemson.h89473761.Hotel-Information) Anderson [](https://www.expedia.com/Anderson-Hotels-Lake-Hartwell-Frank-Howard-Home-Clemson.h89473761.Hotel-Information) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/113000000/112470000/112464400/112464340/8d8778c6.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/113000000/112470000/112464400/112464340/9c4042e8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/113000000/112470000/112464400/112464340/a549cea5.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Front of property](https://images.trvl-media.com/lodging/113000000/112470000/112464400/112464340/099a6462.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Luxe Keowee Key Living: Golf Views & Resort Pool [](https://www.expedia.com/Salem-Hotels-Golf-Course-View-Modern-Keowee-Key-Condo.h112464340.Hotel-Information) Salem [](https://www.expedia.com/Salem-Hotels-Golf-Course-View-Modern-Keowee-Key-Condo.h112464340.Hotel-Information) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/109000000/108450000/108444600/108444520/5525119f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/109000000/108450000/108444600/108444520/a31ab2bb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/109000000/108450000/108444600/108444520/f3e42928.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/109000000/108450000/108444600/108444520/d3e3f6c8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Private Balcony: Lake Keowee Home w/ Pool Access [](https://www.expedia.com/Salem-Hotels-Lake-Keowee-Townhome-W-Marina-Pool-Access.h108444520.Hotel-Information) Salem [](https://www.expedia.com/Salem-Hotels-Lake-Keowee-Townhome-W-Marina-Pool-Access.h108444520.Hotel-Information) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/95000000/94390000/94382100/94382038/1a03e1b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/95000000/94390000/94382100/94382038/3d5f6f95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/95000000/94390000/94382100/94382038/461e3c7b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/95000000/94390000/94382100/94382038/9c5ca6a3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Views, Pools & Marina: Lake Keowee Condo! [](https://www.expedia.com/Salem-Hotels-Lake-Keowee-Condo-W-Views-Pools-Marina.h94382038.Hotel-Information) Salem [](https://www.expedia.com/Salem-Hotels-Lake-Keowee-Condo-W-Views-Pools-Marina.h94382038.Hotel-Information) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537500/93537444/4b6ece41.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537500/93537444/9472950c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537500/93537444/51da12ba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537500/93537444/81a18f98.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lake Keowee Resort Condo: Waterfront Balcony [](https://www.expedia.com/Salem-Hotels-Sunny-Lake-Keowee-Condo-W-Waterfront-Balcony.h93537444.Hotel-Information) Salem 10/10 Exceptional (1 review) "Very clean. Amazing amenities. Lake view that takes your breath away." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Tiffany [](https://www.expedia.com/Salem-Hotels-Sunny-Lake-Keowee-Condo-W-Waterfront-Balcony.h93537444.Hotel-Information) ![Family House, 4 Bedrooms, Patio, Courtyard View | Private kitchen | Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/106000000/105560000/105550100/105550047/f91516fb.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family House, 4 Bedrooms, Patio, Courtyard View | View from room](https://images.trvl-media.com/lodging/106000000/105560000/105550100/105550047/769a03d3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Front of property](https://images.trvl-media.com/lodging/106000000/105560000/105550100/105550047/c252d911.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Family House, 4 Bedrooms, Patio, Courtyard View | In-room dining](https://images.trvl-media.com/lodging/106000000/105560000/105550100/105550047/87cae821.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Belvedere [](https://www.expedia.com/Anderson-Hotels-Belvedere.h105550047.Hotel-Information) Anderson 8.0/10 Very Good (1 review) "Bring everything. Including hangers for your clothes, salt and pepper, etc. it is like staying at a place that has one purpose, to rent out. Beds are uncomfortable. Nice big closets with one wire hanger. Why??? " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) CANDACE $418 nightly $464 total Mar 5 - Mar 6 Total with taxes and fees [](https://www.expedia.com/Anderson-Hotels-Belvedere.h105550047.Hotel-Information) ![Apartment (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/109000000/108010000/108002400/108002358/d76a95da.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3 Bedrooms) | Front of property](https://images.trvl-media.com/lodging/109000000/108010000/108002400/108002358/a2b95b3e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/109000000/108010000/108002400/108002358/866bc49d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (3 Bedrooms) | Interior](https://images.trvl-media.com/lodging/109000000/108010000/108002400/108002358/b1968ba4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Keowee Key Condo w/ Lake Access & Community Pools! [](https://www.expedia.com/Salem-Hotels-Keowee-Key-Condo-W-Lake-Access-Community-Pools.h108002358.Hotel-Information) Salem [](https://www.expedia.com/Salem-Hotels-Keowee-Key-Condo-W-Lake-Access-Community-Pools.h108002358.Hotel-Information) ![Apartment (1 Bedroom) | Front of property](https://images.trvl-media.com/lodging/94000000/93540000/93537200/93537133/9fa693a7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537200/93537133/69d5ed43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537200/93537133/c292a0ab.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537200/93537133/c224b6bc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Keowee Keys Home w/ Mountains View & Lake Access! [](https://www.expedia.com/Salem-Hotels-Gated-Keowee-Keys-Home-W-Mtn-View-Lake-Access.h93537133.Hotel-Information) Salem 8.0/10 Very Good (1 review) "upstairs guestroom has difficult ceiling and space for taller person. Property is in great condition. Wish the queen bed was a king." ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) KURT [](https://www.expedia.com/Salem-Hotels-Gated-Keowee-Keys-Home-W-Mtn-View-Lake-Access.h93537133.Hotel-Information) ![Apartment (4 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98551500/98551451/5388a21f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (4 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98551500/98551451/2ad3fd14.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (4 Bedrooms) | Interior](https://images.trvl-media.com/lodging/99000000/98560000/98551500/98551451/db481623.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (4 Bedrooms) | Front of property](https://images.trvl-media.com/lodging/99000000/98560000/98551500/98551451/036e1b57.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Charming Seneca Home - 3 Mi to Memorial Stadium! [](https://www.expedia.com/Seneca-Hotels-Charming-Seneca-Home-3-Mi-To-Memorial-Stadium.h98551451.Hotel-Information) Seneca [](https://www.expedia.com/Seneca-Hotels-Charming-Seneca-Home-3-Mi-To-Memorial-Stadium.h98551451.Hotel-Information) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/105000000/104100000/104092200/104092180/5a84c846.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/105000000/104100000/104092200/104092180/51ecd543.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/105000000/104100000/104092200/104092180/c12fc109.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/105000000/104100000/104092200/104092180/fa66f600.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lakefront Seneca Vacation Rental w/ Shared Dock! [](https://www.expedia.com/Seneca-Hotels-Lakefront-Seneca-Vacation-Rental-W-Shared-Dock.h104092180.Hotel-Information) Seneca [](https://www.expedia.com/Seneca-Hotels-Lakefront-Seneca-Vacation-Rental-W-Shared-Dock.h104092180.Hotel-Information) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537200/93537195/c556be56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537200/93537195/8092f8fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537200/93537195/513fd8fc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/94000000/93540000/93537200/93537195/a379d456.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Lake Keowee Condo w/ Balcony & Resort Amenities! [](https://www.expedia.com/Salem-Hotels-Lake-Keowee-Condo-W-Balcony-Resort-Amenities.h93537195.Hotel-Information) Salem [](https://www.expedia.com/Salem-Hotels-Lake-Keowee-Condo-W-Balcony-Resort-Amenities.h93537195.Hotel-Information) ![Dock](https://images.trvl-media.com/lodging/112000000/111440000/111438900/111438806/ed9aaf39.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature House, 3 Bedrooms, Kitchen, Lake View | In-room dining](https://images.trvl-media.com/lodging/112000000/111440000/111438900/111438806/895db893.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature House, 3 Bedrooms, Kitchen, Lake View | Private kitchen | Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/112000000/111440000/111438900/111438806/1d672e2b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Signature House, 3 Bedrooms, Kitchen, Lake View | Private kitchen | Fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/112000000/111440000/111438900/111438806/e9f9aeba.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### 228 Lakeland [](https://www.expedia.com/Anderson-Hotels-228-Lakeland.h111438806.Hotel-Information) Anderson [](https://www.expedia.com/Anderson-Hotels-228-Lakeland.h111438806.Hotel-Information) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/108000000/107270000/107264300/107264271/3104feb4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/108000000/107270000/107264300/107264271/80c0fa07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/108000000/107270000/107264300/107264271/656632be.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/108000000/107270000/107264300/107264271/3031d180.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Marina Villa Condo at Lake Keowee w/ Fireplace [](https://www.expedia.com/Salem-Hotels-Lakeside-Salem-Condo-W-Balcony-Fireplace.h107264271.Hotel-Information) Salem [](https://www.expedia.com/Salem-Hotels-Lakeside-Salem-Condo-W-Balcony-Fireplace.h107264271.Hotel-Information) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/110000000/109460000/109450500/109450463/e56f8c84.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/110000000/109460000/109450500/109450463/20b0b105.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/110000000/109460000/109450500/109450463/9487d905.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/110000000/109460000/109450500/109450463/a04f2cd8.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Keowee Key Condo w/ Lake Access! [](https://www.expedia.com/Keowee-Key-Condo-W-Lake-Access.h109450463.Hotel-Information) Salem [](https://www.expedia.com/Keowee-Key-Condo-W-Lake-Access.h109450463.Hotel-Information) ![Interior](https://images.trvl-media.com/lodging/95000000/94430000/94420200/94420141/d2c9ce6b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/95000000/94430000/94420200/94420141/8b62977a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Apartment (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/95000000/94430000/94420200/94420141/708794c2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Interior](https://images.trvl-media.com/lodging/95000000/94430000/94420200/94420141/85ed3ba4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Resort-style Condo w/ Balcony on Lake Keowee [](https://www.expedia.com/Salem-Hotels-New-Resort-Style-Condo-W-Balcony-On-Lake-Keowee.h94420141.Hotel-Information) Salem [](https://www.expedia.com/Salem-Hotels-New-Resort-Style-Condo-W-Balcony-On-Lake-Keowee.h94420141.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Clemson-Hotels.s40-0-d6594.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F4Star-Clemson-Hotels.s40-0-d6594.Travel-Guide-Filter-Hotels) ## Learn more about Clemson Football Saturdays transform this college town into a sea of orange where tailgating is practically a competitive sport. Explore Lake Hartwell's peaceful shores during the day, then head downtown where local restaurants serve Southern classics with a modern twist. [See all hotels in Clemson](https://www.expedia.com/Hotel-Search?startDate=2026-03-18&endDate=2026-03-19&adults=2®ionId=6594) ![Sunset on the Docks in Clemson, South Carolina; Shutterstock ID 1068665087; purchase_order: SP-1269 HA 2018 Batch 1; Order: ; client: ; other:](https://images.trvl-media.com/place/6594/3559af33-8fc4-4b07-8fe6-f8db466d3d41.jpg?impolicy=fcrop&w=900&h=600&p=1&q=high) ## Top Clemson Hotel Reviews ![The Shepherd Hotel Downtown Clemson](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/bd45b45c_y.jpg) ### The Shepherd Hotel Downtown Clemson 10/10 Excellent "All was excellent" [](https://expedia.com/Clemson-Hotels-The-Shepherd-Hotel-Downtown-Clemson.h87688155.Hotel-Information) ## Find out more about Clemson ## Clemson Four Star Hotel Information When you need to book a room with luxurious amazing amenities and the best rates, the 4 star hotels in Clemson, South Carolina are incredible options. Known for their extra perks, first-rate service, and fantastic locations, each of the Clemson 4 star hotels offers the ultimate experience for globe-trotting travelers. Relax in your expertly designed room. Kick back with around-the-clock room service. Get a good night’s sleep with the ultra-plush bedding, and freshen up in the morning with designer-inspired body products. It’s all available when you stay at one of the top book a four star hotels in Clemson. What’s more, thanks to Expedia you might even score a cheap great deal on a 4 star hotel in Clemson, South Carolina, areas near the hottest attractions, so you can plan a sightseeing adventure and take advantage of unbeatable discounts in one fell swoop. Whether you’re putting together a serene getaway or want to revel in the most vibrant entertainment district, 4 star Clemson hotels offer everything your heart desires. ## Frequently asked questions ### How much does it cost to stay in a 4-star hotel in Clemson? > - Search for the lowest price from $210 ### What's the difference between 5-star and 4-star hotels in Clemson? ### Does Clemson have any 4-star all-inclusive resorts? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - [Hotels near Clemson University ](https://www.expedia.com/Clemson-University-Hotels.0-l6127431-0.Travel-Guide-Filter-Hotels) - [Hotels near Memorial Stadium ](https://www.expedia.com/Memorial-Stadium-Hotels.0-l6193935-0.Travel-Guide-Filter-Hotels) - [Hotels near Fort Hill ](https://www.expedia.com/Fort-Hill-Hotels.0-l553248621532656693-0.Travel-Guide-Filter-Hotels) - [Hotels near Larry W. Abernathy Waterfront Park ](https://www.expedia.com/Larry-W-Abernathy-Waterfront-Park-Hotels.0-l553248621532656695-0.Travel-Guide-Filter-Hotels) - [Hotels near Littlejohn Coliseum ](https://www.expedia.com/Littlejohn-Coliseum-Hotels.0-l6228662-0.Travel-Guide-Filter-Hotels) - [Hotels near Clemson Station ](https://www.expedia.com/Clemson-Station-Hotels.d6194530.Travel-Guide-Hotels) - [Hotels near Brooks Center for the Performing Arts ](https://www.expedia.com/Brooks-Center-For-The-Performing-Arts-Hotels.0-l6228683-0.Travel-Guide-Filter-Hotels) - [Hotels near South Carolina Botanical Gardens ](https://www.expedia.com/South-Carolina-Botanical-Gardens-Hotels.0-l6228711-0.Travel-Guide-Filter-Hotels) - [Hotels near Walker Golf Course ](https://www.expedia.com/Walker-Golf-Course-Hotels.0-l6228657-0.Travel-Guide-Filter-Hotels) - [Gay friendly Hotels in Keowee ](https://www.expedia.com/Keowee-Hotels-LGBT-Welcoming-Hotel.0-0-d553248635975848347-tLGBTWelcomingHotel.Travel-Guide-Filter-Hotels) - [Hotels near Oconee County Regional ](https://www.expedia.com/Oconee-County-Regional-Airport-Hotels.0-aCEU-0.Travel-Guide-Filter-Hotels) - [Flights from Oconee County Regional ](https://www.expedia.com/lp/airports/ceu/flights-from-oconee-county-regional-airport) - [Flights from Atlanta (ATL) to Clemson (CEU) ](https://www.expedia.com/lp/flights/atl/ceu/atlanta-to-clemson) - [Flights from Charlotte (CLT) to Clemson (CEU) ](https://www.expedia.com/lp/flights/clt/ceu/charlotte-to-clemson) - [Flights from New York (JFK) to Clemson (CEU) ](https://www.expedia.com/lp/flights/jfk/ceu/new-york-to-clemson) - [Flights from Boston (BOS) to Clemson (CEU) ](https://www.expedia.com/lp/flights/bos/ceu/boston-to-clemson) - [Flights from Asheville (AVL) to Clemson (CEU) ](https://www.expedia.com/lp/flights/avl/ceu/asheville-to-clemson) - [Flights from Washington (DCA) to Clemson (CEU) ](https://www.expedia.com/lp/flights/dca/ceu/washington-to-clemson) - [Flights from Philadelphia (PHL) to Clemson (CEU) ](https://www.expedia.com/lp/flights/phl/ceu/philadelphia-to-clemson) - [Flights from Miami (MIA) to Clemson (CEU) ](https://www.expedia.com/lp/flights/mia/ceu/miami-to-clemson) - [Flights from Tampa (TPA) to Clemson (CEU) ](https://www.expedia.com/lp/flights/tpa/ceu/tampa-to-clemson) - [Flights from Chicago (ORD) to Clemson (CEU) ](https://www.expedia.com/lp/flights/ord/ceu/chicago-to-clemson) - [Flights from Nashville (BNA) to Clemson (CEU) ](https://www.expedia.com/lp/flights/bna/ceu/nashville-to-clemson) - [Flights from Pittsburgh (PIT) to Clemson (CEU) ](https://www.expedia.com/lp/flights/pit/ceu/pittsburgh-to-clemson) - [Flights from Dallas (DFW) to Clemson (CEU) ](https://www.expedia.com/lp/flights/dfw/ceu/dallas-to-clemson) - [Flights to Oconee County Regional ](https://www.expedia.com/Cheap-Flights-To-Oconee-County-Regional.d6026946.Travel-Guide-Flights) - [Flights from Tallahassee (TLH) to Clemson (CEU) ](https://www.expedia.com/lp/flights/tlh/ceu/tallahassee-to-clemson) - [Flights from Baltimore (BWI) to Clemson (CEU) ](https://www.expedia.com/lp/flights/bwi/ceu/baltimore-to-clemson) - [Flights from Hartford (BDL) to Clemson (CEU) ](https://www.expedia.com/lp/flights/bdl/ceu/hartford-to-clemson) - [Flights from Austin (AUS) to Clemson (CEU) ](https://www.expedia.com/lp/flights/aus/ceu/austin-to-clemson) - [Flights from Augusta (AGS) to Clemson (CEU) ](https://www.expedia.com/lp/flights/ags/ceu/augusta-to-clemson) - [Flights from Richmond (RIC) to Clemson (CEU) ](https://www.expedia.com/lp/flights/ric/ceu/richmond-to-clemson) - [Flights from Syracuse (SYR) to Clemson (CEU) ](https://www.expedia.com/lp/flights/syr/ceu/syracuse-to-clemson) - [Flights from Indianapolis (IND) to Clemson (CEU) ](https://www.expedia.com/lp/flights/ind/ceu/indianapolis-to-clemson) - [Flights from Albany (ALB) to Clemson (CEU) ](https://www.expedia.com/lp/flights/alb/ceu/albany-to-clemson) - [Flights from Chattanooga (CHA) to Clemson (CEU) ](https://www.expedia.com/lp/flights/cha/ceu/chattanooga-to-clemson) - [Flights from Fort Lauderdale (FLL) to Clemson (CEU) ](https://www.expedia.com/lp/flights/fll/ceu/fort-lauderdale-to-clemson) - [Flights from Jacksonville (JAX) to Clemson (CEU) ](https://www.expedia.com/lp/flights/jax/ceu/jacksonville-to-clemson) - [Flights from Memphis (MEM) to Clemson (CEU) ](https://www.expedia.com/lp/flights/mem/ceu/memphis-to-clemson) - [Flights from Hilton Head Island (HHH) to Clemson (CEU) ](https://www.expedia.com/lp/flights/hhh/ceu/hilton-head-island-to-clemson) - [Flights from Lexington (LEX) to Clemson (CEU) ](https://www.expedia.com/lp/flights/lex/ceu/lexington-to-clemson) - [Flights from Denver (DEN) to Clemson (CEU) ](https://www.expedia.com/lp/flights/den/ceu/denver-to-clemson) - [Flights from New York (LGA) to Clemson (CEU) ](https://www.expedia.com/lp/flights/lga/ceu/new-york-to-clemson) - [Flights from West Palm Beach (PBI) to Clemson (CEU) ](https://www.expedia.com/lp/flights/pbi/ceu/west-palm-beach-to-clemson) - [Flights from Fort Myers (RSW) to Clemson (CEU) ](https://www.expedia.com/lp/flights/rsw/ceu/fort-myers-to-clemson) - [Flights from Orlando (ORL) to Clemson (CEU) ](https://www.expedia.com/lp/flights/orl/ceu/orlando-to-clemson) - [Flights from Houston (HOU) to Clemson (CEU) ](https://www.expedia.com/lp/flights/hou/ceu/houston-to-clemson) - [Flights from Los Angeles (LAX) to Clemson (CEU) ](https://www.expedia.com/lp/flights/lax/ceu/los-angeles-to-clemson) - [Flights from Minneapolis (MSP) to Clemson (CEU) ](https://www.expedia.com/lp/flights/msp/ceu/minneapolis-to-clemson) - [Flights from St. Louis (STL) to Clemson (CEU) ](https://www.expedia.com/lp/flights/stl/ceu/st-louis-to-clemson) - [Flights from San Francisco (SFO) to Clemson (CEU) ](https://www.expedia.com/lp/flights/sfo/ceu/san-francisco-to-clemson) - [Flights from Buffalo (BUF) to Clemson (CEU) ](https://www.expedia.com/lp/flights/buf/ceu/buffalo-to-clemson) - [Flights from Auburn (AUO) to Clemson (CEU) ](https://www.expedia.com/lp/flights/auo/ceu/auburn-to-clemson) - [Flights from Seattle (SEA) to Clemson (CEU) ](https://www.expedia.com/lp/flights/sea/ceu/seattle-to-clemson) - [Flights from Washington (IAD) to Clemson (CEU) ](https://www.expedia.com/lp/flights/iad/ceu/washington-to-clemson) - [Flights from Madison (MSN) to Clemson (CEU) ](https://www.expedia.com/lp/flights/msn/ceu/madison-to-clemson) - [Flights from Cleveland (CLE) to Clemson (CEU) ](https://www.expedia.com/lp/flights/cle/ceu/cleveland-to-clemson) - [Flights from Florence (FLR) to Clemson (CEU) ](https://www.expedia.com/lp/flights/flr/ceu/florence-to-clemson) - [Flights from Harrisburg (MDT) to Clemson (CEU) ](https://www.expedia.com/lp/flights/mdt/ceu/harrisburg-to-clemson) - [Flights from Phoenix (PHX) to Clemson (CEU) ](https://www.expedia.com/lp/flights/phx/ceu/phoenix-to-clemson) - [Flights from Rochester (ROC) to Clemson (CEU) ](https://www.expedia.com/lp/flights/roc/ceu/rochester-to-clemson) - [Flights from Burlington (BTV) to Clemson (CEU) ](https://www.expedia.com/lp/flights/btv/ceu/burlington-to-clemson) - [Flights from Portland (PDX) to Clemson (CEU) ](https://www.expedia.com/lp/flights/pdx/ceu/portland-to-clemson) - [Flights from Grand Rapids (GRR) to Clemson (CEU) ](https://www.expedia.com/lp/flights/grr/ceu/grand-rapids-to-clemson) - [Flights from Sarasota (SRQ) to Clemson (CEU) ](https://www.expedia.com/lp/flights/srq/ceu/sarasota-to-clemson) - 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[Flights from Toledo (TOL) to Clemson (CEU) ](https://www.expedia.com/lp/flights/tol/ceu/toledo-to-clemson) - [Flights from Wilkes-Barre (AVP) to Clemson (CEU) ](https://www.expedia.com/lp/flights/avp/ceu/wilkes-barre-to-clemson) - [Flights from Oakland (OAK) to Clemson (CEU) ](https://www.expedia.com/lp/flights/oak/ceu/oakland-to-clemson) - [Flights from Orlando (SFB) to Clemson (CEU) ](https://www.expedia.com/lp/flights/sfb/ceu/orlando-to-clemson) - [Flights from Binghamton (BGM) to Clemson (CEU) ](https://www.expedia.com/lp/flights/bgm/ceu/binghamton-to-clemson) - [Flights from New York (NYC) to Clemson (CEU) ](https://www.expedia.com/lp/flights/nyc/ceu/new-york-to-clemson) - [Flights from Mexico City (MEX) to Clemson (CEU) ](https://www.expedia.com/lp/flights/mex/ceu/mexico-city-to-clemson) - [Flights from San Juan (SJU) to Clemson (CEU) ](https://www.expedia.com/lp/flights/sju/ceu/san-juan-to-clemson) - [Flights from Gatlinburg (GKT) to Clemson (CEU) ](https://www.expedia.com/lp/flights/gkt/ceu/gatlinburg-to-clemson) - [Flights from Panama City (PTY) to Clemson (CEU) ](https://www.expedia.com/lp/flights/pty/ceu/panama-city-to-clemson) - [Flights from Colorado Springs (COS) to Clemson (CEU) ](https://www.expedia.com/lp/flights/cos/ceu/colorado-springs-to-clemson) - [Flights from Fresno (FAT) to Clemson (CEU) ](https://www.expedia.com/lp/flights/fat/ceu/fresno-to-clemson) - [Flights from Moline (MLI) to Clemson (CEU) ](https://www.expedia.com/lp/flights/mli/ceu/moline-to-clemson) - [Larry W. Abernathy Waterfront Park ](https://www.expedia.com/Larry-W-Abernathy-Waterfront-Park-Clemson.d553248621532656695.Vacation-Attraction) - [Fort Hill ](https://www.expedia.com/Fort-Hill-Clemson.d553248621532656693.Vacation-Attraction) - [Memorial Stadium ](https://www.expedia.com/Memorial-Stadium-Clemson.d6193935.Vacation-Attraction) - [Clemson University ](https://www.expedia.com/Clemson-University-Clemson.d6127431.Vacation-Attraction) - [Littlejohn Coliseum ](https://www.expedia.com/Littlejohn-Coliseum-Clemson.d6228662.Vacation-Attraction) - [Lee Gallery ](https://www.expedia.com/Lee-Gallery-Clemson.d553248621532656692.Vacation-Attraction) - [Brooks Center for the Performing Arts ](https://www.expedia.com/Brooks-Center-For-The-Performing-Arts-Clemson.d6228683.Vacation-Attraction) - [South Carolina Botanical Gardens ](https://www.expedia.com/South-Carolina-Botanical-Gardens-Clemson.d6228711.Vacation-Attraction) - [Van Car Rentals near Clemson University ](https://www.expedia.com/Van-Car-Rentals-In-Clemson-University.d6127431-tVan.Car-Rental-Guide-Class) - [Car rentals near Clemson University ](https://www.expedia.com/Car-Rentals-In-Clemson-University.d6127431.Car-Rental-Guide) - [Car rentals near Littlejohn Coliseum ](https://www.expedia.com/Car-Rentals-In-Littlejohn-Coliseum.d6228662.Car-Rental-Guide) - [Car rentals near Keowee ](https://www.expedia.com/Car-Rentals-In-Keowee.d553248635975848347.Car-Rental-Guide) - [Car rental Seneca Airport (CEU) ](https://www.expedia.com/Car-Rentals-In-Oconee-County-Regional.d6026946.Car-Rental-Guide)