A calm lake with mountains in the background and a sunset.

Find 4 Star Hotels in Clemson, SC from $152

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Check availability on Clemson 4 Star Hotels

Tonight
Oct 24 - Oct 25
Tomorrow
Oct 25 - Oct 26
Next weekend
Oct 30 - Nov 1
In two weeks
Nov 6 - Nov 8

Our top choices for Clemson 4-star hotels

A modern lounge area with a brick accent wall, a fireplace, and comfortable seating.
A modern living room with a sofa, two armchairs, a coffee table, and a potted plant.
A multi-story hotel with a prominent entrance, a parking lot, and a landscaped area with a small tree.
A hotel room with a bed, a sofa, a dining table with chairs, a coffee machine, and a TV mounted on the wall.

1. The Abernathy of Clemson

The Abernathy of Clemson
Clemson
United States
Amy
$140 nightly
$156 total
Nov 17 - Nov 18
Total with taxes and fees
The Abernathy of Clemson
A multi-level interior with a spiral staircase, wooden railings, and a seating area with tables and chairs.
An outdoor patio with wicker furniture, a round table, and a fountain.
A spacious restaurant with high ceilings, wooden flooring, and a mix of modern and classic furniture.
A spacious living area with a sofa, ottoman, and chairs, a dining area with a table, and a kitchen in the background.

2. The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson
Clemson
United States
Laurrie
$209 nightly
$232 total
Oct 26 - Oct 27
Total with taxes and fees
The Shepherd Hotel Downtown Clemson
A white, two-story house with a front porch, surrounded by trees and shrubs.
A two-story building with a white exterior, a front door, and a balcony.
A bedroom with two beds, a TV, and a fireplace.
A hallway with a wooden bench, a chair, a cabinet, and a painting on the wall.

3. Liberty Hall Bed and Breakfast

Liberty Hall Bed and Breakfast
Pendleton
United States
Christine
$137 nightly
$152 total
Nov 5 - Nov 6
Total with taxes and fees
Liberty Hall Bed and Breakfast
A cozy living room with a fireplace, leather armchair, and a large window.
A wooden gazebo with a roof, surrounded by trees, overlooking a lake.
A modern kitchen with stainless steel appliances, a granite countertop, and large windows offering a view of the outdoors.
A covered outdoor deck with wicker furniture and large windows offering views of a forest and a lake.

4. Designer Retreat w/ Pool, Golf + Beach Access!

Designer Retreat w/ Pool, Golf + Beach Access!
Salem
United States
Anonymous traveler
Designer Retreat w/ Pool, Golf + Beach Access!
A two-story yellow house with a front porch, a small garden, and a pathway leading to the entrance.
A two-story yellow house with a front porch, surrounded by greenery and a driveway.
Interior
An indoor swimming pool with clear lanes, a covered roof, and a bench area.

5. Wooded Keowee Key Retreat Near Golf & Trails

Wooded Keowee Key Retreat Near Golf & Trails
Salem
Wooded Keowee Key Retreat Near Golf & Trails
A swimming pool with a view of a lake and docked boats.
A spacious dining area with a wooden table, chairs, and a chandelier. A cozy seating area with a sofa and chairs is visible in the background.
A sandy beach with a calm lake surrounded by trees.
A marina with boats docked, a lifeguard station, and a dock with lounge chairs.

6. Lake Keowee Condo: Resort Pools & Lake Access!

Lake Keowee Condo: Resort Pools & Lake Access!
Salem
United States
Shawn
Lake Keowee Condo: Resort Pools & Lake Access!
A spacious dining area with a wooden table and chairs, a fireplace, and large windows offering a view of the outdoors.
A modern kitchen with white cabinets, a wooden island, stainless steel appliances, and a tiled floor.
A two-story house with a covered porch and a front yard.
A spacious dining area with a wooden table and chairs, a large rug, and a view of the kitchen and outdoor area.

7. Lake Hartwell Frank Howard Home Clemson

Lake Hartwell Frank Howard Home Clemson
Anderson
Lake Hartwell Frank Howard Home Clemson
A swimming pool with a view of the lake and docked boats.
A marina with boats docked, surrounded by greenery and trees.
A modern living room with a large window, a flat-screen TV, a leather sofa, a coffee table, and a bookshelf.
A spacious living area with a high ceiling, a large window with a view of trees, a kitchen with a bar, and a comfortable seating area with a sofa and ottomans.

8. Keowee Key Condo w/ Lake Access & Community Pools!

Keowee Key Condo w/ Lake Access & Community Pools!
Salem
Keowee Key Condo w/ Lake Access & Community Pools!
A wooden deck with a table and chairs, large windows, and a view of trees.
A dining area with a wooden table and chairs, a kitchen with white cabinets, and a staircase with a white railing.
A marina with boats docked, surrounded by greenery and trees.
A swimming pool with a view of a lake and docked boats.

9. Salem Vacation Rental w/ Lake Keowee Access!

Salem Vacation Rental w/ Lake Keowee Access!
Salem
Salem Vacation Rental w/ Lake Keowee Access!
A swimming pool with a view of the lake and docked boats.
A gazebo with a wooden roof and open sides, surrounded by trees and overlooking a body of water.
An aerial view of a residential area with houses, a golf course, and a lake in the background.
A sandy beach with a calm lake surrounded by trees.

10. Views, Pools & Marina: Lake Keowee Condo!

Views, Pools & Marina: Lake Keowee Condo!
Salem
Views, Pools & Marina: Lake Keowee Condo!
A multi-story wooden building with balconies, large windows, and a landscaped area with trees.
A modern living room with a sofa, a coffee table, and a fireplace.
A spacious hotel lobby with a bar area, seating arrangements, and large windows offering views.
A modern building with a prominent wooden entrance canopy, stone pillars, and a clear sky.

11. Tee Times & Lake Days! Luxe Keowee Key Living

Tee Times & Lake Days! Luxe Keowee Key Living
Salem
Tee Times & Lake Days! Luxe Keowee Key Living
Interior
A multi-story hotel with a parking lot and a view of a lake.
A marina with boats docked, a wooden pier, and a clear sky.
A hallway with a wooden bench, a chandelier, a door, and a wall with a sign.

12. Lake Keowee Condo w/ Balcony & Resort Amenities!

Lake Keowee Condo w/ Balcony & Resort Amenities!
Salem
United States
Kathleen
Lake Keowee Condo w/ Balcony & Resort Amenities!
A spacious kitchen with a large island, wooden cabinets, and pendant lighting.
A spacious living area with a large flat-screen TV, a wooden cabinet, a grey sofa set, and a patterned ottoman.
A spacious living room with a dining area, large windows, and a ceiling fan.
A modern kitchen with a central island, bar stools, and pendant lighting.

13. 5 Mi to Memorial Stadium & Beach: Modern Townhome

5 Mi to Memorial Stadium & Beach: Modern Townhome
Central
5 Mi to Memorial Stadium & Beach: Modern Townhome
A modern living room with a green sofa, a leather armchair, a fireplace, and a television mounted on the wall.
A balcony with a glass table and wicker chairs, overlooking a lake and trees.
A bedroom with a white wardrobe, a flat-screen TV, and a painting on the wall.
A kitchen with white cabinets, a stainless steel refrigerator, a coffee maker, and a toaster.

14. Lake Keowee Resort Condo w/ Fantastic View

Lake Keowee Resort Condo w/ Fantastic View
Salem
United States
Tiffany
Lake Keowee Resort Condo w/ Fantastic View
A spacious living room with a wooden ceiling, large windows, a dining table with chairs, a sofa, and a flat-screen TV.
A cozy living room with a sofa, coffee table, and a view of the kitchen.
A bedroom with a sloped ceiling, a bed with a floral bedspread, a dresser, a television, and a window with a view of trees.
A marina with boats docked, a pier, and a forested area in the background.

15. Keowee Keys Home w/ Mountains View & Lake Access!

Keowee Keys Home w/ Mountains View & Lake Access!
Salem
United States
KURT
Keowee Keys Home w/ Mountains View & Lake Access!
A covered porch with a sofa and coffee table, surrounded by trees.
A spacious kitchen with granite countertops, wooden cabinets, a dishwasher, and a large window with blinds.
A spacious room with a pool table, a foosball table, and a red leather couch.
A bedroom with a bed, a dresser, a ceiling fan, and a window.

16. Clemson Game Day Villa Near Campus & Lakes

Clemson Game Day Villa Near Campus & Lakes
Clemson
Clemson Game Day Villa Near Campus & Lakes
A covered patio with wooden chairs and a table, overlooking a fenced yard with a body of water and trees.
A two-story house with a dark roof, a garage, and a large rock in the foreground.
A house with a pathway leading to a dock, surrounded by trees and a body of water.
A spacious living area with a sofa set, a glass coffee table, and a ceiling fan.

17. Lakefront Seneca Vacation Rental w/ Shared Dock!

Lakefront Seneca Vacation Rental w/ Shared Dock!
Seneca
Lakefront Seneca Vacation Rental w/ Shared Dock!
A house with a front porch, a door, and two chairs.
A living room with a sofa, a coffee table, a television, a lamp, a bookshelf, and a ceiling fan.
A dining area with a wooden table, chairs, a ceiling fan, and a view of the kitchen through a window.
A two-story house with a garage, surrounded by trees and a well-maintained lawn.

18. Clemson Weekends 3 Mi From Memorial Stadium

Clemson Weekends 3 Mi From Memorial Stadium
Seneca
Clemson Weekends 3 Mi From Memorial Stadium
A two-story house with a covered porch, a brick pathway leading to the front door, and a well-maintained lawn.
A two-story house with a paved driveway leading to the front door.
A spacious room with a large sliding glass door leading to an outdoor patio area.
A bathroom with a white sink, a toilet, a mirror, and a window with blinds.

19. 228 Lakeland

228 Lakeland
Anderson
228 Lakeland
A swimming pool with a view of a lake and docked boats.
A wooden gazebo with a roof, surrounded by trees, overlooking a lake.
A private beach with a stone pathway leading to the water, surrounded by trees and a wooden fence.
A sandy beach with a calm lake surrounded by trees.

20. Keowee Key Condo w/ Lake Access!

Keowee Key Condo w/ Lake Access!
Salem
Keowee Key Condo w/ Lake Access!
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Learn more about Clemson

Football Saturdays transform this college town into a sea of orange where tailgating is practically a competitive sport. Explore Lake Hartwell's peaceful shores during the day, then head downtown where local restaurants serve Southern classics with a modern twist.

See all hotels in Clemson
A historic building with a clock tower, surrounded by a well-maintained lawn with a paw print design.

Top Clemson Hotel Reviews

Find out more about Clemson

Clemson Four Star Hotel Information

When you need to book a room with luxurious amazing amenities and the best rates, the 4 star hotels in Clemson, South Carolina are incredible options. Known for their extra perks, first-rate service, and fantastic locations, each of the Clemson 4 star hotels offers the ultimate experience for globe-trotting travelers. Relax in your expertly designed room. Kick back with around-the-clock room service.

Get a good night’s sleep with the ultra-plush bedding, and freshen up in the morning with designer-inspired body products. It’s all available when you stay at one of the top book a four star hotels in Clemson. What’s more, thanks to Expedia you might even score a cheap great deal on a 4 star hotel in Clemson, South Carolina, areas near the hottest attractions, so you can plan a sightseeing adventure and take advantage of unbeatable discounts in one fell swoop.

Whether you’re putting together a serene getaway or want to revel in the most vibrant entertainment district, 4 star Clemson hotels offer everything your heart desires.

Frequently asked questions

How much does it cost to stay in a 4-star hotel in Clemson?
To book a 4-star hotel in Clemson that fits your budget, take advantage of Expedia's handy search filters. Browse what's available during your preferred dates and use our pricing filter to set your maximum rate. You can also list your results by the most economical escape first.
  • Search for the lowest price from $152
What's the difference between 5-star and 4-star hotels in Clemson?
Offering a friendly guest experience and upscale décor, 4-star hotels are a fabulous option for your Clemson break. These kinds of stays generally come with loads of useful amenities that make it a breeze to unpack and relax — think complimentary bathrobes, gyms and pools. Or enjoy even more lavishness at a 5-star hotel designed to pamper with luxury perks and amenities. A personalized service, oversized bathrooms and world-class dining are typically included at these swanky properties.
Does Clemson have any 4-star all-inclusive resorts?
Finding vacation bliss in Clemson is as easy as typing in your travel details and selecting our "All inclusive" filter. Stay and play where everything is already taken care of like your accommodations, meals and activities, or choose a standard 4-star resort in or around this sought-after destination.

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