A calm lake with mountains in the background and a sunset.

Find 4 Star Hotels in Clemson, SC from $165

Check availability on Clemson 4 Star Hotels

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Oct 10 - Oct 11
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Oct 11 - Oct 12
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Oct 16 - Oct 18
In two weeks
Oct 23 - Oct 25

Our top choices for Clemson 4-star hotels

A modern lounge area with a brick accent wall, a fireplace, and comfortable seating.
A multi-story hotel with a prominent entrance, a parking lot, and a landscaped area with a small tree.
A bar area with a counter, multiple chairs, and a display of bottles and glasses.
A hotel room with a bed, a sofa, a dining table with chairs, a coffee machine, and a TV mounted on the wall.

1. The Abernathy of Clemson

The Abernathy of Clemson
Clemson
United States
Amy
$149 nightly
$165 total
Oct 18 - Oct 19
Total with taxes and fees
The Abernathy of Clemson
A multi-level interior with a spiral staircase, wooden railings, and a seating area with tables and chairs.
An outdoor patio with wicker furniture, a round table, and a fountain.
A spacious living area with a sofa, ottoman, and chairs, a dining area with a table, and a kitchen in the background.
A modern bar area with a wooden ceiling, green bar stools, and a bar counter.

2. The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson
Clemson
United States
Laurrie
$188 nightly
$209 total
Oct 18 - Oct 19
Total with taxes and fees
The Shepherd Hotel Downtown Clemson
A white, two-story house with a front porch, surrounded by trees and shrubs.
A hallway with a wooden bench, a chair, a cabinet, and a painting on the wall.
A dining area with round tables, black chairs, and white tablecloths.
A bedroom with two beds, a TV, and a fireplace.

3. Liberty Hall Bed and Breakfast

Liberty Hall Bed and Breakfast
Pendleton
United States
Christine
$174 nightly
$193 total
Oct 11 - Oct 12
Total with taxes and fees
Liberty Hall Bed and Breakfast
A wooden gazebo with a roof, surrounded by trees, overlooking a lake.
A marina with boats docked, a lifeguard station, and a dock with lounge chairs.
A modern kitchen with stainless steel appliances, a granite countertop, and large windows offering a view of the outdoors.
A cozy living room with a fireplace, leather armchair, and a large window.

4. Designer Retreat w/ Pool, Golf + Beach Access!

Designer Retreat w/ Pool, Golf + Beach Access!
Salem
United States
Anonymous traveler
Designer Retreat w/ Pool, Golf + Beach Access!
An indoor swimming pool with clear lanes, a covered roof, and a bench area.
Interior
Interior
A two-story yellow house with a front porch, a small garden, and a pathway leading to the entrance.

5. Wooded Keowee Key Retreat Near Golf & Trails

Wooded Keowee Key Retreat Near Golf & Trails
Salem
Wooded Keowee Key Retreat Near Golf & Trails
A spacious dining area with a wooden table and chairs, a fireplace, and large windows offering a view of the outdoors.
A modern kitchen with white cabinets, a wooden island, stainless steel appliances, and a tiled floor.
A two-story house with a covered porch and a front yard.
A spacious dining area with a wooden table and chairs, a large rug, and a view of the kitchen and outdoor area.

6. Lake Hartwell Frank Howard Home Clemson

Lake Hartwell Frank Howard Home Clemson
Anderson
Lake Hartwell Frank Howard Home Clemson
Interior
A marina with boats docked, a wooden pier, and a clear sky.
A kitchen with white cabinets, a stainless steel refrigerator, a microwave, and a sink.
A multi-story hotel with a parking lot and a view of a lake.

7. Lake Keowee Condo w/ Balcony & Resort Amenities!

Lake Keowee Condo w/ Balcony & Resort Amenities!
Salem
United States
Kathleen
Lake Keowee Condo w/ Balcony & Resort Amenities!
A marina with boats docked, a lifeguard station, and a dock with lounge chairs.
An indoor swimming pool with clear lanes, a covered roof, and a bench area.
A multi-story hotel with a parking lot and a view of a lake.
A spacious dining area with a wooden table, chairs, and a chandelier. A cozy seating area with a sofa and chairs is visible in the background.

8. Lake Keowee Condo: Resort Pools & Lake Access!

Lake Keowee Condo: Resort Pools & Lake Access!
Salem
United States
Shawn
Lake Keowee Condo: Resort Pools & Lake Access!
A gazebo with a wooden roof and open sides, surrounded by trees and overlooking a body of water.
A spacious living room with a fireplace, a television, and a staircase leading to an upper level.
A marina with boats docked, surrounded by greenery and trees.
A dining area with a wooden table and chairs, a kitchen with white cabinets, and a staircase with a white railing.

9. Salem Vacation Rental w/ Lake Keowee Access!

Salem Vacation Rental w/ Lake Keowee Access!
Salem
Salem Vacation Rental w/ Lake Keowee Access!
A gazebo with a wooden roof and open sides, surrounded by trees and overlooking a body of water.
A marina with boats docked, a lifeguard station, and a view of a lake surrounded by trees.
A sandy beach with a calm lake surrounded by trees.
A large indoor swimming pool with clear lanes, a covered roof, and seating areas along the sides.

10. Views, Pools & Marina: Lake Keowee Condo!

Views, Pools & Marina: Lake Keowee Condo!
Salem
Views, Pools & Marina: Lake Keowee Condo!
A wooden gazebo with a roof and a table and chairs inside, surrounded by trees and overlooking a lake.
A modern living room with a sofa, a coffee table, and a fireplace.
A modern kitchen with a stainless steel sink, pendant lighting, and a view to a living area with a sofa and a staircase.
A modern building with a prominent wooden entrance canopy, stone pillars, and a clear sky.

11. Tee Times & Lake Days! Luxe Keowee Key Living

Tee Times & Lake Days! Luxe Keowee Key Living
Salem
Tee Times & Lake Days! Luxe Keowee Key Living
A swimming pool with a view of the lake and docked boats.
A modern kitchen with a central island, stainless steel appliances, wooden cabinets, and a window providing natural light.
A spacious living area with a high ceiling, a large window with a view of trees, a kitchen with a bar, and a comfortable seating area with a sofa and ottomans.
A marina with boats docked, surrounded by greenery and trees.

12. Keowee Key Condo w/ Lake Access & Community Pools!

Keowee Key Condo w/ Lake Access & Community Pools!
Salem
Keowee Key Condo w/ Lake Access & Community Pools!
A spacious living room with a wooden ceiling, large windows, a dining table with chairs, a sofa, and a flat-screen TV.
A cozy living room with a sofa, coffee table, and a view of the kitchen.
A marina with boats docked, a pier, and a forested area in the background.
A marina with boats docked, a wooden pier, and a sign warning against feeding the waterfowl.

13. Keowee Keys Home w/ Mountains View & Lake Access!

Keowee Keys Home w/ Mountains View & Lake Access!
Salem
United States
KURT
Keowee Keys Home w/ Mountains View & Lake Access!
A balcony with a glass table and wicker chairs, overlooking a lake and trees.
A parking lot with multiple cars, a building with a flat roof, and trees in the background.
A calm lake with docked boats, surrounded by dense trees and a clear sky.
A hallway with a bench, a painting of a seascape, and a door with a sign.

14. Lake Keowee Resort Condo w/ Fantastic View

Lake Keowee Resort Condo w/ Fantastic View
Salem
United States
Tiffany
Lake Keowee Resort Condo w/ Fantastic View
A spacious kitchen with a large island, wooden cabinets, and pendant lighting.
A spacious living area with a large flat-screen TV, a wooden cabinet, a grey sofa set, and a patterned ottoman.
A modern kitchen with a central island, bar stools, and pendant lighting.
A residential house with a covered porch, a well-maintained lawn, and a clear sky.

15. 5 Mi to Memorial Stadium & Beach: Modern Townhome

5 Mi to Memorial Stadium & Beach: Modern Townhome
Central
5 Mi to Memorial Stadium & Beach: Modern Townhome
A wooden gazebo with a roof, surrounded by trees, overlooking a lake.
A private beach with a stone pathway leading to the water, surrounded by trees and a wooden fence.
A marina with boats docked, a lifeguard station, and a dock with lounge chairs.
An indoor swimming pool with clear lanes, a covered roof, and blue and white flags.

16. Keowee Key Condo w/ Lake Access!

Keowee Key Condo w/ Lake Access!
Salem
Keowee Key Condo w/ Lake Access!
A covered porch with a sofa and coffee table, surrounded by trees.
A dining area with a chandelier, wooden chairs, and a table set for four.
A spacious room with a pool table, a foosball table, and a red leather couch.
A spacious kitchen with granite countertops, wooden cabinets, a dishwasher, and a large window with blinds.

17. Clemson Game Day Villa Near Campus & Lakes

Clemson Game Day Villa Near Campus & Lakes
Clemson
Clemson Game Day Villa Near Campus & Lakes
A covered patio with wooden chairs and a table, overlooking a fenced yard with a body of water and trees.
A spacious living area with a sofa set, a glass coffee table, and a ceiling fan.
A house with a pathway leading to a dock, surrounded by trees and a body of water.
A two-story house with a dark roof, a garage, and a large rock in the foreground.

18. Lakefront Seneca Vacation Rental w/ Shared Dock!

Lakefront Seneca Vacation Rental w/ Shared Dock!
Seneca
Lakefront Seneca Vacation Rental w/ Shared Dock!
A wooden gazebo with a roof, surrounded by trees, overlooking a lake.
A living room with a fireplace, a ceiling fan, and a large window.
An indoor swimming pool with clear lanes, a covered roof, and blue and white flags.
A private beach with a stone pathway leading to the water, surrounded by trees and a wooden fence.

19. Marina Villa Condo at Lake Keowee w/ Fireplace

Marina Villa Condo at Lake Keowee w/ Fireplace
Salem
Marina Villa Condo at Lake Keowee w/ Fireplace
A house with a front porch, a door, and two chairs.
A living room with a sofa, a coffee table, a television, a lamp, a bookshelf, and a ceiling fan.
A two-story house with a garage, surrounded by trees and a well-maintained lawn.
A porch with two white chairs, a white door with a paw print, and orange shutters.

20. Clemson Weekends 3 Mi From Memorial Stadium

Clemson Weekends 3 Mi From Memorial Stadium
Seneca
Clemson Weekends 3 Mi From Memorial Stadium
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Learn more about Clemson

Football Saturdays transform this college town into a sea of orange where tailgating is practically a competitive sport. Explore Lake Hartwell's peaceful shores during the day, then head downtown where local restaurants serve Southern classics with a modern twist.

See all hotels in Clemson
A historic building with a clock tower, surrounded by a well-maintained lawn with a paw print design.

Top Clemson Hotel Reviews

The Shepherd Hotel Downtown Clemson

The Shepherd Hotel Downtown Clemson

10/10 Excellent
"lovely hotel and wonderful staff"
MartinandHeather 1-night trip
Posted 2 days ago
The Shepherd Hotel Downtown Clemson

Find out more about Clemson

Clemson Four Star Hotel Information

When you need to book a room with luxurious amazing amenities and the best rates, the 4 star hotels in Clemson, South Carolina are incredible options. Known for their extra perks, first-rate service, and fantastic locations, each of the Clemson 4 star hotels offers the ultimate experience for globe-trotting travelers. Relax in your expertly designed room. Kick back with around-the-clock room service.

Get a good night’s sleep with the ultra-plush bedding, and freshen up in the morning with designer-inspired body products. It’s all available when you stay at one of the top book a four star hotels in Clemson. What’s more, thanks to Expedia you might even score a cheap great deal on a 4 star hotel in Clemson, South Carolina, areas near the hottest attractions, so you can plan a sightseeing adventure and take advantage of unbeatable discounts in one fell swoop.

Whether you’re putting together a serene getaway or want to revel in the most vibrant entertainment district, 4 star Clemson hotels offer everything your heart desires.

Frequently asked questions

How much does it cost to stay in a 4-star hotel in Clemson?
To book a 4-star hotel in Clemson that fits your budget, take advantage of Expedia's handy search filters. Browse what's available during your preferred dates and use our pricing filter to set your maximum rate. You can also list your results by the most economical escape first.
  • Search for the lowest price from $165
What's the difference between 5-star and 4-star hotels in Clemson?
Offering a friendly guest experience and upscale décor, 4-star hotels are a fabulous option for your Clemson break. These kinds of stays generally come with loads of useful amenities that make it a breeze to unpack and relax — think complimentary bathrobes, gyms and pools. Or enjoy even more lavishness at a 5-star hotel designed to pamper with luxury perks and amenities. A personalized service, oversized bathrooms and world-class dining are typically included at these swanky properties.
Does Clemson have any 4-star all-inclusive resorts?
Finding vacation bliss in Clemson is as easy as typing in your travel details and selecting our "All inclusive" filter. Stay and play where everything is already taken care of like your accommodations, meals and activities, or choose a standard 4-star resort in or around this sought-after destination.

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