Find 5 Star Hotels in Brentwood, MO from $144

Start date: Check-in selected.
End date: Check-out

Check availability on Brentwood 5 Star Hotels

Tonight
Sep 3 - Sep 4
Tomorrow
Sep 4 - Sep 5
This weekend
Sep 5 - Sep 7
Next weekend
Sep 12 - Sep 14

Compare Brentwood 5 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Our top choices for Brentwood 5-star hotels

The Ritz-Carlton, St. Louis
Meeting facility

The Ritz-Carlton, St. Louis

5.0 star property
9.2 out of 10, Wonderful, (547)
"Service is exceptional!!!"
$519 nightly
The price is $605
Sep 21 - Sep 22
Total with taxes and fees
The Ritz-Carlton, St. Louis
Four Seasons Hotel St Louis
Rooftop bar

Four Seasons Hotel St Louis

5.0 star property
9.4 out of 10, Exceptional, (1000)
"We’ve stayed at this hotel several times and keep coming back. Great hotel staff and property. "
$425 nightly
The price is $497
Sep 13 - Sep 14
Total with taxes and fees
Four Seasons Hotel St Louis
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Brentwood.
Renaissance St. Louis Airport Hotel

Renaissance St. Louis Airport Hotel

9801 Natural Bridge Road, St. Louis, MO
$123 nightly
The price is $144 total per night from Oct 3 to Oct 4
$144 total
Oct 3 - Oct 4
Total with taxes and fees
Still don't see what you're looking for?
See all properties in Brentwood.
You can also use these popular filters to refine your search.
PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Brentwood Hotel Reviews

Find out more about Brentwood

Find out more about Brentwood

There's nothing wrong with enjoying the finer things in life. Add even more enjoyment on your next trip to Brentwood by treating yourself to the best of the best when it comes to accommodation. It's an ideal pairing. There's no reason to delay a getaway to Brentwood any longer. You'll join the multitudes of vacationers who have made Brentwood so fashionable in the last year. Besides that, you'll find that these hotels are kept in excellent condition and provide a fine place to kick back after your daily adventures. What are you waiting for? Our 5-star hotels in Brentwood are the perfect places to relax in when you really need to escape.

5-Star Hotels in Brentwood

Don't be afraid to live the high life while you're on vacation, along with the best conditions. Highly-rated eateries, excellent customer care, and deeply relaxing spa offerings are all on offer. You're sure to find exactly the accommodation you need. Besides that, you'll find that these hotels are kept in excellent condition and provide a fine place to lay your head at night. How do you want to relax? 24-hour room service, so you can order that Turkish coffee in the wee hours of the morning? A mud wrap treatment that will leave you feeling outstanding? Butler services? No matter what you want on a perfect getaway, you're bound to find it here. Want to see for yourself? Explore the review section and see what previous visitors have said. You're sure to find exactly what you're looking for!

But you aren't going to spend your entire vacation in your room, of course. You're in luck. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what you end up doing, the 5-star hotels in Brentwood are the perfect place to rest up after a busy day.

Make Your Escape

The results are in, and Brentwood 5-star hotels are the place to be when you book your next vacation. These beautiful hotels are highly rated by the guests who stay in them, and you're about to join their ranks. Your great getaway is just a mouse-click away -- Expedia can help you land a great deal on accommodation. Select one of our Brentwood 5-star hotels today and dive into in total tranquility tomorrow.

Explore a world of travel with Expedia

Explore a world of travel with Expedia

Frequently asked questions

What are the best 5-star hotels in Brentwood?
Step into a world of luxury at The Ritz-Carlton, St. Louis. This is one of the most highly rated 5-star hotels in Brentwood based on reviews by Expedia guests. From its plush guest rooms to its premium amenities and services, you can count on the highest standard of excellence.
How much does it cost to stay in a 5-star hotel in Brentwood?
The amount you pay for a 5-star hotel in Brentwood depends on factors such as when you plan to go and the length of your stay. Our insider tip for scoring the best deal? Use our pricing filters to compare the available accommodations for your selected dates.

  • Search for the lowest price per night from $144

What makes a hotel 5 stars in Brentwood?
In Brentwood, a hotel must offer a certain level of high-end amenities to earn a 5-star rating. These may include on-site gyms, gourmet restaurants, saunas and spas, premium bedding, complimentary luxury toiletries and more. What also sets 5-star hotels apart is their guest-centric standard of service. You'll enjoy things like nightly turn-down services, concierge services and in-room massages. Some may even offer extra touches like a welcome gift.