A wooden pier extending into calm waters at sunset, with a thatched-roof structure at the end.

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Check availability on Destin 5 Star Hotels

Tonight
Sep 22 - Sep 23
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Sep 23 - Sep 24
This weekend
Sep 25 - Sep 27
Next weekend
Oct 2 - Oct 4

Our top choices for Destin 5-star hotels

A beachfront property with a large building, sandy beach, and ocean.
A balcony with a view of a resort pool, beach, and hotel buildings.
A spacious dining area with high ceilings, ceiling fans, and decorative lighting.
A hotel with a pool, lounge chairs, and umbrellas.

1. The Henderson Beach Resort & Spa

The Henderson Beach Resort & Spa
Crystal Beach
United States
HUMBERTO DE
$345 nightly
$390 total
Oct 21 - Oct 22
Total with taxes and fees
The Henderson Beach Resort & Spa
A multi-story beachfront house with a balcony, a patio, and a view of the ocean.
A balcony with a view of the ocean, featuring a railing and a seating area.
A spacious living room with a large sectional sofa, a fireplace, and a view of the ocean.
A pool area with lounge chairs and a hot tub, surrounded by palm trees and a building with large windows.

2. Capitano 7 Bedroom Holiday Home by Five Star Properties

Capitano 7 Bedroom Holiday Home by Five Star Properties
Destin
Capitano 7 Bedroom Holiday Home by Five Star Properties
A beach with clear turquoise water, white sand, and a row of buildings along the shore.
A covered outdoor area with a table and chairs, a pool, and a view of a building and palm trees.
A multi-story residential building with a swimming pool and hot tub.
A spacious kitchen with a large island, white cabinetry, and a wooden ceiling.

3. Stranded on a Sandbar 8 Bedroom Holiday Home by Five Star Properties

Stranded on a Sandbar 8 Bedroom Holiday Home by Five Star Properties
Frangista Beach
Stranded on a Sandbar 8 Bedroom Holiday Home by Five Star Properties
A spacious bedroom with a large bed, a ceiling fan, and a view of the outdoors through large windows.
A pool area with a hot tub, lounge chairs, and a view of the ocean at dusk.
A spacious living room with a fireplace, a large sofa, a coffee table, and a television mounted on the wall.
A multi-story beachfront property with balconies, large windows, and a staircase leading to the entrance.

4. Millenia 7 Bedroom Holiday Home by Five Star Properties

Millenia 7 Bedroom Holiday Home by Five Star Properties
Destin
Millenia 7 Bedroom Holiday Home by Five Star Properties

5. Palazzo del Mar by Five Star Properties

Palazzo del Mar by Five Star Properties
Crystal Beach
Palazzo del Mar by Five Star Properties
A beachfront property with a multi-story building, balconies, and a view of the ocean at sunset.
A spacious room with a large bed, a sofa, and a fireplace.
A spacious living room with a large sectional sofa, two coffee tables, and a ceiling fan.
A balcony with a view of the ocean at sunset, furnished with a sofa, chairs, and a table.

6. Palazzo del Mar 11 Bedroom Holiday Home by Five Star Properties

Palazzo del Mar 11 Bedroom Holiday Home by Five Star Properties
Crystal Beach
Palazzo del Mar 11 Bedroom Holiday Home by Five Star Properties

7. Casa Esmeralda by Five Star Properties

Casa Esmeralda by Five Star Properties
Destin
Casa Esmeralda by Five Star Properties
A multi-story building with a central courtyard, featuring arched balconies and palm trees.
A spacious kitchen with a large island, white cabinetry, and a decorative ceiling.
A multi-level building with arches and columns, featuring a balcony with railings and lights.
A balcony with a view of the ocean, featuring a pergola structure and a railing.

8. Vista del Mare 4 Bedroom Holiday Home by Five Star Properties

Vista del Mare 4 Bedroom Holiday Home by Five Star Properties
Destin
Vista del Mare 4 Bedroom Holiday Home by Five Star Properties

9. Modern Paradise by Five Star Properties

Modern Paradise by Five Star Properties
Destin
Modern Paradise by Five Star Properties
A multi-story building with balconies, palm trees, and a well-lit entrance.
A grand staircase with a marble floor, flanked by columns and framed pictures, leading to a door.
An aerial view of a coastal area with a long sandy beach, adjacent residential buildings, and a clear blue ocean.
A balcony with a wicker chair and a small table, overlooking a residential area with palm trees and houses.

10. Casa de Palms 5 Bedroom Holiday Home by Five Star Properties

Casa de Palms 5 Bedroom Holiday Home by Five Star Properties
Avalon Beach Estates
Casa de Palms 5 Bedroom Holiday Home by Five Star Properties
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Destin.
The Island Resort at Fort Walton Beach

The Island Resort at Fort Walton Beach

Miracle Strip Parkway Southeast, 1500 Fort Walton Beach FL
$145 nightly
$164 total
Oct 20 - Oct 21
Total with taxes and fees
The Island Resort at Fort Walton Beach
Hotel Effie Sandestin, Autograph Collection

Hotel Effie Sandestin, Autograph Collection

1 Grand Sandestin Boulevard Miramar Beach FL
$266 nightly
$298 total
Oct 13 - Oct 14
Total with taxes and fees
9.2/10 Wonderful! (1,000 reviews)
Hotel Effie Sandestin, Autograph Collection
Hilton Sandestin Beach Golf Resort & Spa

Hilton Sandestin Beach Golf Resort & Spa

4000 S Sandestin Blvd Miramar Beach FL
$302 nightly
$338 total
Oct 18 - Oct 19
Total with taxes and fees
9/10 Wonderful! (1,003 reviews)
Hilton Sandestin Beach Golf Resort & Spa
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Destin

Sugar-white beaches and emerald waters make this Gulf Coast paradise perfect for snorkeling, dolphin cruises, and fresh seafood dining. Venture beyond the sand to explore Henderson Beach State Park's nature trails or book a deep-sea fishing charter where captains know exactly where the big ones hide.

See all hotels in Destin
An aerial view of a coastal town with a beach, marina, and residential areas.

Top Destin Hotel Reviews

The Henderson Beach Resort & Spa

The Henderson Beach Resort & Spa

10/10 Excellent
"Best place ever! Clean, unique, good for family in general or couple!"
ENRIQUE 4-night trip
Posted 3 days ago
The Henderson Beach Resort & Spa

Find out more about Destin

Ready to experience the next standard in luxury? We know you are thinking about it. Pamper yourself on your upcoming leisure time. There's no reason to delay a getaway to Destin any longer. You'll join the multitudes of vacationers who have made Destin so fashionable in the last year. Besides that, you'll find that these hotels are kept in fantastic condition and provide a fine place to lay your head at night. What are you waiting for? Reserve one of our 5-star hotels in Destin and indulge in the finer things in life for a while.

Get a Great Deal on 5-Star Hotels in Destin

Don't be afraid to live the high life while you're on vacation, along with pristine rooms. Highly-rated eateries, concierges, and in-room spa sessions are all at the ready. You're sure to find exactly the accommodation you need. Besides that, you'll find that these hotels are kept in fantastic condition and provide a fine place to kick back after your daily adventures. What creature comforts do you want in your lodging? A reflexology treatment that will leave you feeling outstanding? 24-hour room service, so you can order that filet mignon in the wee hours of the morning? A rejuvenating facial treatment to help your cares fall away? Want to see for yourself? Then explore the 711 reviews various guests have left on Expedia and get to know these places. Maybe all these awesome ratings are why the number of visits grew from 2015 to 2016!

But you aren't going to spend your entire vacation in your room, of course. You're in luck. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what you end up doing, the 5-star hotels in Destin are waiting for you to relax after an exciting day.

Make Your Escape

Numerous visitors make Destin the place to vacation. Why not join their ranks? Many visitors recommend a trip to this location, so don't wait any longer. It's time to indulge yourself -- a surge in interest means these great hotel rooms will go quickly. Choose one of Expedia's Destin 5-star hotels today and relax in total tranquility at your convenience.

Frequently asked questions

What are the best 5-star hotels in Destin?
Boasting premium amenities and guest services, our customers rate The Henderson Beach Resort & Spa as one of the best 5-star hotels in Destin. You'll be immersed in a world of luxury from the moment you step foot into the lobby.
How much does it cost to stay in a 5-star hotel in Destin?
There are several pricing options for a 5-star hotel in Destin on Expedia. The amount you pay will depend on when you travel, length of your trip and other factors. Compare all of the available properties for your preferred dates and make use of our pricing and other filters to score the ideal high-end stay.
  • Search for the lowest price per night from $164
What makes a hotel 5 stars in Destin?
Exemplary guest service is at the heart of every 5-star hotel in Destin. From the minute you arrive, staff attend to your every need, whether answering room service calls 24/7 or providing a nightly turn-down service. Additionally, hotels have to feature top-rate amenities to be eligible for a 5-star rating. These can include luxury bathrooms, an on-site spa, swimming pools, gastronomic restaurants and knowledgeable concierge.

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