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Our top choices for Byron hotels

Kahler Grand Hotel

Kahler Grand Hotel
3.0 star property
Downtown Rochester
8.4 out of 10, Very Good, (1,980 reviews)
"The access to the Mayo Clinic from the Kahler was helpful."
United States
Leon
7 days ago
$140 nightly
The price is $161
Apr 27 - Apr 28
Total with taxes and fees
Kahler Grand Hotel

EVEN Hotel Rochester - Mayo Clinic Area by IHG

EVEN Hotel Rochester - Mayo Clinic Area by IHG
4.0 star property
Kutzky Park
9.4 out of 10, Exceptional, (1,005 reviews)
"Hotel is great. Large rooms with blackout shades."
United States
Sara
1 day ago
$117 nightly
The price is $134
Apr 24 - Apr 25
Total with taxes and fees
EVEN Hotel Rochester - Mayo Clinic Area by IHG

AmericInn by Wyndham Rochester Near Mayo Clinic

AmericInn by Wyndham Rochester Near Mayo Clinic
3.0 star property
Rochester
8.0 out of 10, Very Good, (1,251 reviews)
"Pool play area looked amazing. My room was clean."
United States
Deborah
November 11th, 2025
$73 nightly
The price is $84
Apr 12 - Apr 13
Total with taxes and fees
AmericInn by Wyndham Rochester Near Mayo Clinic

Hyatt House Rochester/Mayo Clinic Area

Hyatt House Rochester/Mayo Clinic Area
3.0 star property
Downtown Rochester
9.0 out of 10, Wonderful, (1,008 reviews)
"Staff seemed overwhelmed but nice."
United States
Aliesha
7 days ago
$139 nightly
The price is $160
Apr 10 - Apr 11
Total with taxes and fees
Hyatt House Rochester/Mayo Clinic Area

Aspen Suites

Aspen Suites
3.0 star property
Rochester
9.0 out of 10, Wonderful, (791 reviews)
"Rooms very clean. Provide shuttle services."
United States
Trudie
5 days ago
$145 nightly
The price is $167
Apr 10 - Apr 11
Total with taxes and fees
Aspen Suites

Hotel Indigo Rochester – Mayo Clinic Area by IHG

Hotel Indigo Rochester – Mayo Clinic Area by IHG
3.5 star property
Downtown Rochester
8.8 out of 10, Excellent, (976 reviews)
"Overall nice hotel. Room was clean."
United States
Barbara Elizabeth
13 days ago
$105 nightly
The price is $121
May 7 - May 8
Total with taxes and fees
Hotel Indigo Rochester – Mayo Clinic Area by IHG

Kahler Inn and Suites - Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area
3.5 star property
Downtown Rochester
8.0 out of 10, Very Good, (1,542 reviews)
"The easy subway access to Mayo. Very appreciative that they brought back the included breakfast."
United States
Theresa
6 days ago
$140 nightly
The price is $161
Apr 27 - Apr 28
Total with taxes and fees
Kahler Inn and Suites - Mayo Clinic Area

Staybridge Suites Rochester - Mayo Clinic Area by IHG

Staybridge Suites Rochester - Mayo Clinic Area by IHG
3.0 star property
Kutzky Park
9.4 out of 10, Exceptional, (455 reviews)
"Room was nice. Check in staff was friendly. That breakfast was good."
United States
Shelley
3 days ago
$141 nightly
The price is $162
Apr 11 - Apr 12
Total with taxes and fees
Staybridge Suites Rochester - Mayo Clinic Area by IHG

The Berkman

The Berkman
3.0 star property
Folwell
9.6 out of 10, Exceptional, (402 reviews)
"Amd walking distance to great restaurants."
United States
Michelle
15 days ago
$176 nightly
The price is $202
Apr 9 - Apr 10
Total with taxes and fees
The Berkman

Brentwood Inn & Suites

Brentwood Inn & Suites
2.5 star property
Downtown Rochester
8.8 out of 10, Excellent, (1,002 reviews)
"Always a decent stay. People are nice and rooms clean."
United States
Catherine
4 days ago
$130 nightly
The price is $150
Apr 9 - Apr 10
Total with taxes and fees
Brentwood Inn & Suites

Hampton Inn Rochester-South

Hampton Inn Rochester-South
2.5 star property
Rochester
9.0 out of 10, Wonderful, (1,002 reviews)
"I really liked the check in guy he's a seamstress."
United States
Susan
8 days ago
$93 nightly
The price is $107
May 3 - May 4
Total with taxes and fees
Hampton Inn Rochester-South

Hilton Rochester Mayo Clinic Area

Hilton Rochester Mayo Clinic Area
3.5 star property
Downtown Rochester
9.6 out of 10, Exceptional, (587 reviews)
"Reasonably priced restaurants within the hotel. My go to option for treatment visits."
United States
Jerome F.
February 6th, 2026
$171 nightly
The price is $197
Apr 24 - Apr 25
Total with taxes and fees
Hilton Rochester Mayo Clinic Area

Home2 Suites by Hilton Rochester Mayo Clinic Area

Home2 Suites by Hilton Rochester Mayo Clinic Area
3.0 star property
Rochester
9.6 out of 10, Exceptional, (938 reviews)
"Rooms are clean. Standard Hilton breakfast. Staff is working hard."
United States
Natasha
October 27th, 2025
$127 nightly
The price is $146
Apr 24 - Apr 25
Total with taxes and fees
Home2 Suites by Hilton Rochester Mayo Clinic Area

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys
3.0 star property
Kutzky Park
8.6 out of 10, Excellent, (986 reviews)
"Mark the magician at gust services waa excellent!!"
United States
Xena
3 days ago
$94 nightly
The price is $108
May 8 - May 9
Total with taxes and fees
SpringHill Suites by Marriott Rochester-Mayo Clinic/St Marys

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Best Western Rochester Hotel Mayo Clinic Area/St. Mary's
2.5 star property
Rochester
8.2 out of 10, Very Good, (875 reviews)
"Clean room, friendly staff, and great accommodations."
United States
Robert
1 day ago
$94 nightly
The price is $108
Apr 14 - Apr 15
Total with taxes and fees
Best Western Rochester Hotel Mayo Clinic Area/St. Mary's

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys
3.0 star property
Kutzky Park
9.6 out of 10, Exceptional, (695 reviews)
"Breakfast area was kept clean. Parking was good."
United States
Sara
9 days ago
$103 nightly
The price is $118
Apr 24 - Apr 25
Total with taxes and fees
Fairfield Inn & Suites Rochester Mayo Clinic Area/St. Marys

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area
3.0 star property
Historic Southwest
8.6 out of 10, Excellent, (1,006 reviews)
"Clean room, staff was kind and extremely helpful as always, shuttle service was excellent!"
United States
Kali
4 days ago
$108 nightly
The price is $124
Apr 27 - Apr 28
Total with taxes and fees
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area

Med City Inn & Suites - Mayo Clinic Area
2.5 star property
Kutzky Park
7.8 out of 10, Good, (1,007 reviews)
"The room was very clean. Amenities were good. Breakfast was good."
United States
Karen
2 days ago
$76 nightly
The price is $87
Apr 27 - Apr 28
Total with taxes and fees
Med City Inn & Suites - Mayo Clinic Area

TownePlace Suites by Marriott Rochester Mayo Clinic Area

TownePlace Suites by Marriott Rochester Mayo Clinic Area
3.0 star property
Kutzky Park
9.6 out of 10, Exceptional, (507 reviews)
"Front desk staff helpful. Cleaning staff thorough. Perfect for visiting Mayo Clinic."
United States
Sasha
23 days ago
$118 nightly
The price is $136
Apr 24 - Apr 25
Total with taxes and fees
TownePlace Suites by Marriott Rochester Mayo Clinic Area

Aspen Select

Aspen Select
3.5 star property
Kutzky Park
8.4 out of 10, Very Good, (1,004 reviews)
"Room was very clean. Decent continental breakfast."
United States
Derek
7 days ago
$131 nightly
The price is $151
Apr 9 - Apr 10
Total with taxes and fees
Aspen Select
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Stay near popular Byron attractions

Top Byron Hotel Reviews

More cheap stays in Byron

Hotels in Byron with star-rating

Find out more about Byron

Top reasons to visit Byron

  • Scenic Recreational Areas: Enjoy leisurely strolls and picnics in Byron's beautiful parks.
  • Top-Notch Golf Courses: Perfect for golfers of all skill levels, Byron features excellent golf facilities.
  • Family-Friendly Attractions: Explore urban parks and museums that cater to diverse interests for all ages.
  • Charming Neighborhoods: Experience the welcoming atmosphere and friendliness of the locals.
  • Diverse Accommodations: Find a range of lodging options, including pet-friendly and LGBTQIA-friendly hotels.

Find great hotels near Byron

Explore a variety of hotel accommodations in Byron, Minnesota, ideal for both business travelers and leisure seekers. From comfortable motels to welcoming hotels, you'll find pet-friendly options and LGBTQIA-friendly experiences. Whether you're searching for hotels near Byron or seeking a cozy stay in the area, Byron offers diverse lodging choices to suit your needs and preferences.

  • Med City Inn & Suites - Mayo Clinic Area: Located 8 miles from Byron, Med City Inn & Suites offers a cozy, budget-friendly lodging experience perfect for families and pet lovers. This motel-style accommodation features a welcoming atmosphere with amenities tailored for children, including an arcade game room, highchairs, and a family-friendly pool area. Pets are also welcome, making it an ideal choice for those traveling with furry companions. The property’s focus on family and comfort ensures a pleasant stay for all.
  • Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic: Just 7 miles from Byron, Microtel Inn & Suites is a great option for business travelers seeking a convenient and comfortable stay. Rated 8.0 out of 10, this budget-friendly hotel features modern accommodations designed for productivity and relaxation. Guests will appreciate the contemporary amenities and friendly service, making it a solid choice for those visiting the Mayo Clinic or conducting business in the area.
  • Best Western Rochester Hotel Mayo Clinic Area/St. Mary's: Situated 8 miles from Byron, this well-rated hotel (8.4 out of 10) combines comfort and convenience for families and pet owners alike. The Best Western offers a range of amenities for children such as a pool with a safety gate, arcade games, and breakfast options tailored for younger guests. With a pet-friendly policy and a welcoming environment, this hotel is an excellent choice for those looking to enjoy a family vacation while still having the option to bring their pets along.

Where to stay near Byron

Byron, Minnesota, offers a delightful blend of outdoor adventures and family-friendly attractions. Explore the charming neighborhoods and enjoy the welcoming atmosphere of friendly locals. Nearby Fort Valley provides additional opportunities for fun and relaxation, while local hospitals ensure peace of mind during your stay. Whether you're seeking a city-themed getaway or an outdoor retreat, Byron is the perfect destination for a memorable vacation experience.

  • Kasson: Located a short 6 miles from Byron, Kasson is a vibrant city that attracts travelers year-round for its family-friendly atmosphere, business-themed opportunities, and outdoor activities. Visitors often flock here during the peak months of June to July and September. Kasson offers a range of popular venues, including shopping centers and an arena entertainment facility. Nature enthusiasts will appreciate the local parks, while those seeking events can find suitable venues for conferences and gatherings. With its welcoming community and diverse attractions, Kasson is a delightful stop during your vacation.
  • Mantorville: Also situated 6 miles from Byron, Mantorville is a charming city known for its blend of outdoor activities and family-oriented experiences. The peak travel months are April and the summer from July to August, making it an ideal destination for those seeking fun in the sun. Visitors can enjoy recreational areas, golf courses, and educational venues. Mantorville boasts scenic urban parks and a lovely lake, perfect for a day of relaxation or outdoor fun. Its quaint atmosphere and unique attractions make Mantorville a must-visit for travelers looking to explore the area.
  • Northwest: Just 7 miles from Byron, the Northwest neighborhood is a hidden gem for those who love outdoor adventures and sports. Although visitor numbers peak in the summer months of July to August, it remains a year-round destination. Here, you can find excellent golfing options and shopping centers. The local landmarks, including a picturesque lake and an exhilarating theme park with a waterpark, offer numerous activities for families and thrill-seekers alike. Northwest is a perfect choice for an active vacation, blending leisure and excitement in one locale.

Things to do in Byron

Byron, Minnesota, offers a delightful mix of outdoor and family-friendly activities perfect for a city-themed vacation. Visitors can enjoy the scenic recreational area, perfect for leisurely strolls and picnics, as well as top-notch golf courses that cater to both beginners and seasoned players. Whether you're looking to relax in nature or hit the greens, Byron has something to keep everyone entertained.

Shopping

In Byron, you can explore local shops like Byron Marketplace for unique gifts and souvenirs. If you're up for a drive, visit the nearby Apache Mall in Rochester for a wider selection of stores, offering everything from fashion to home goods.

Recreation

In Byron, Minnesota, the Haven Retreat Center provides a serene atmosphere for yoga and meditation, surrounded by nature. Nearby, the Byron Community Center offers fitness classes and recreational activities, perfect for rejuvenating your mind and body while enjoying a sense of community.

Adventure

Explore the scenic trails at Byron's nature parks for hiking and wildlife spotting. The nearby Zumbro River offers canoeing and kayaking adventures, perfect for enjoying the tranquil waters. Don’t miss the chance to bike along the picturesque routes, immersing yourself in the beautiful landscapes of the area.

Nightlife

Byron, Minnesota offers a cozy nightlife scene with local favorites like the Byron Pub for a casual drink and live music. For a more upscale experience, check out the nearby Rochester's vibrant downtown, where you’ll find bars and lounges perfect for a fun night out.

*Distances are measured in a straight line; actual driving distances may vary depending on the route.

Booking tips and Expedia advantages for Byron

  • The most and least expensive months on average to stay in a hotel: The cheapest months to stay in Byron are November to January, where the prices are slightly lower. This is in comparison to April to May and October, where prices are slightly higher.
  • The most and least expensive days on average to stay in a hotel: The least expensive day to stay in Byron is Saturday. The most expensive day to stay in Byron is Tuesday.
  • Find cheap hotels on Expedia: Utilize Expedia’s search tool to narrow down your options based on your budget, desired location, and preferred hotel type. To find the best prices and deals, simply arrange the price filter from lowest to highest.
  • Consider bundling your trip: You can save money by combining your hotel stay in Byron with your flights and activities through an Expedia package.

Find the best attractions in Byron

Byron, Minnesota, is perfect for family-friendly outdoor adventures and city-themed vacations. Visitors can enjoy local attractions like urban parks and museums that cater to various interests. Whether you’re seeking a relaxing day outdoors or exploring the area's cultural offerings, Byron has something for everyone, making it an ideal destination for all types of travelers.

  • Oxbow Park: Experience the beauty of nature in this urban park, perfect for families and outdoor enthusiasts. With walking trails, picnic areas, and a serene atmosphere, Oxbow Park invites you to unwind and enjoy the great outdoors right within Byron.
  • Oxbow Nature Center: Discover local culture and history at this engaging museum. The Oxbow Nature Center offers educational exhibits and programs that celebrate the area's natural heritage, making it an enriching stop for visitors of all ages.
  • East Brookfield Park: Another delightful urban park in Byron, East Brookfield Park features spacious play areas, scenic walking paths, and community events, providing a welcoming environment for families and friends to gather and enjoy leisure activities.

Best time to go to Byron

The best time to visit Byron is dependent on what kind of holiday you are seeking. July is its hottest month on average. At this time, visitor numbers are slightly high and weather is mostly sunny with light rain. January is its coolest month on average. At this time, visitor numbers are slightly low and weather is mostly cloudy with no rain.

calendarCalendar MonthtemperatureTemperaturerainPrecipitationmostlyCloudinessoccupationOccupancypricePricing
January14.7°F (-9.6°C)No RainMostly CloudySlightly LowSlightly Low
February16.9°F (-8.4°C)No RainMostly CloudyAverageAverage
March32.5°F (0.3°C)Light RainMostly CloudyAverageAverage
April44.1°F (6.7°C)Light RainMostly CloudyAverageSlightly High
May57.2°F (14.0°C)Light RainMostly SunnyAverageSlightly High
June67.5°F (19.7°C)Light RainMostly SunnySlightly HighAverage
July70.9°F (21.6°C)Light RainMostly SunnySlightly HighAverage
August69.1°F (20.6°C)Light RainMostly SunnyAverageAverage
September62.4°F (16.9°C)Light RainMostly SunnySlightly HighAverage
October48.0°F (8.9°C)Light RainMostly SunnySlightly LowSlightly High
November34.9°F (1.6°C)No RainMostly SunnyAverageSlightly Low
December21.4°F (-5.9°C)Light RainMostly CloudySlightly LowSlightly Low

The nearest major airports for your trip to Byron

Traveling to Byron, Minnesota, is convenient with three major airports nearby. Minneapolis-St. Paul International Airport (MSP) is 65 miles away, with excellent hotels such as the 5-star InterContinental Minneapolis-St. Paul Airport, located 0.5 miles from the airport, and the 4.5-star Radisson Blu Mall of America, just 3 miles away. Rochester International Airport (RST) is only 11 miles from Byron, featuring the 4-star Towers At Kahler Grand Hotel, 8 miles from RST. Lastly, La Crosse Municipal Airport (LSE) is 70 miles away, with nearby options like the 4-star Charmant Hotel, situated 4 miles from LSE, offering various transport services for easy access.

Frequently asked questions

What is the best area to stay in Byron?
For most visitors to Byron, the best area to stay is near the main commercial thoroughfare of Frontage Road, especially for its convenience and access to amenities.

This area, specifically around the intersection of Frontage Road Northwest and 1st Avenue Northwest, serves as the primary hub for hotels and local services. It's designed for ease of access, with most accommodations offering ample parking and straightforward routes to Rochester and the surrounding attractions.

For travelers prioritizing convenience and quick access to nearby Rochester, staying along Frontage Road is ideal.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Byron.
How can I save on a Byron hotel booking with Expedia?
With Expedia, you earn OneKeyCash™* on eligible Byron hotel bookings for every dollar you spend – just join our One Key™ travel rewards program to get started. It's free to join, and you'll unlock our lowest Member Prices as soon as you're signed in. On top of this, you could also save significantly by bundling your hotel and flights together on Expedia.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Byron hotel?
Prices for hotels in Byron often vary, but you can find a great deal from $69 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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