$45 Car Rental Salem, SC

These Salem insights are based on real traveler data from Expedia, aggregated using AI to help you plan your trip. Updated: August 19, 2026.

Reasons to book a car rental in and around Salem

Renting a car in Salem, South Carolina, offers the freedom and flexibility to explore the area at your own pace. With a rental vehicle, you can conveniently visit nearby attractions such as Devils Fork State Park for outdoor adventures and scenic views. Lake Keowee, located just 7 miles away, provides a perfect setting for romantic outings and beach experiences. For family-friendly eco-adventures, Devils Fork Lake Jocassee is also in the vicinity, ensuring there's something for everyone.

The convenience of a rental car extends to exploring nearby cities like Seneca, which is 14 miles away, offering additional parks and scenic spots. Tamassee, only 3 miles from Salem, features both Lake Keowee and Devils Fork State Park, making it easy to enjoy diverse outdoor activities. For those traveling with luggage or planning a leisurely itinerary, a rental car simplifies your travel plans, allowing for easy luggage management. Whether you are seeking a romantic getaway, outdoor adventures, or family experiences, renting a car in Salem enhances your trip by providing the flexibility to explore all that the region has to offer.

Where to stay around Salem

• Tamassee: Located only 3 miles from Salem, Tamassee is ideal for those seeking outdoor adventures and scenic views. Popular attractions include Lake Keowee and Lake Jocassee, both perfect for beach outings and romantic getaways. For nature lovers, Devils Fork State Park offers stunning landscapes and various recreational activities. The area also features local food and drink options including wineries, making it a great spot for relaxation and exploration.
• Seneca: Situated 14 miles from Salem, Seneca is a charming city known for its outdoor activities and scenic beauty. Visitors can enjoy Lake Keowee, which is great for beach activities, or explore urban parks like Highpointe Lower Field and South Cove Park, perfect for family outings. The local dining scene includes several restaurants and wineries, providing delightful culinary experiences after a day of adventure.
• Sapphire: About 15 miles from Salem, Sapphire is a picturesque destination celebrated for its romantic ambiance and outdoor scenery. Key highlights include Whisper Lake and Gorges State Park, both renowned for their stunning views and recreational options. Additionally, the area boasts nearby food and drink venues, including wineries and breweries, making it a wonderful choice for those looking to unwind while soaking in the natural beauty.

10 tips to save on your car rental in and around Salem

1. Use filters to find the right car: Refine your search based on vehicle type and features. Whether you’re looking for an SUV for additional space, a convertible for summer enjoyment, or an economy car for cost savings, utilize the filters on Expedia to discover the best option for your journey.
2. Book in advance to help lower costs: Rental rates vary with demand, so reserving your vehicle well ahead of your trip is advisable. By booking early, you’re more likely to secure lower prices and better availability, especially during peak travel seasons.
3. Consider a smaller car for savings: Compact cars are typically less expensive to rent and easier to maneuver in crowded areas. Mid-size options strike a good balance between affordability, comfort, and fuel efficiency.
4. Age guidelines: Drivers under 30 may encounter higher deposits or daily fees, and certain types of vehicles—such as SUVs or luxury models—might not be available. This can also apply to renters over 70. Be sure to verify the age requirements before making your reservation.
5. Check fuel policies: Some rental agreements require a full-to-full fuel policy, meaning you must return the car with a full tank to avoid extra fees. This is often the most economical choice. Others might offer full-to-empty or prepaid fueling options, which are acceptable as well; just ensure to return the car empty in that case.
6. Save on city and airport pickups: There is often a surcharge for picking up your rental car at airports, but the added convenience may justify the extra cost.
7. Know your payment options: Many car rental companies only accept credit cards for payment.
8. Understand your insurance coverage: Car rental insurance can help you avoid unexpected expenses and provides peace of mind in case something unforeseen occurs during your trip. Adding car rental insurance when booking through Expedia is straightforward.
9. Consider unlimited mileage: If you’re planning long road trips, seek rentals that offer unlimited mileage to prevent additional charges.
10. Bring your driver's license and ID: A valid driver’s license is necessary to rent a car.

Finding the cheapest car rentals in Salem

Using our Search Wizard

If the deals that are available on our page do not suit your needs, then enter Salem into the search wizard at the top of the page. We will compare all the best deals available for your car rental in Salem and provide you with a list of the cheapest options, with no added fees.

Renting a car in Salem

Pay at pickup is available, so you don’t have to worry about spending your money until you arrive at your vehicle in Salem. We partner with reliable partners that guarantee an enjoyable experience for solo travelers, couples, and families. Package your car with a flight or hotel to unlock even more savings from Expedia.

Expected prices in Salem

Prices are subject to seasonal change depending on when you decide to arrange your car rental but right now you can book from $45.

Flexibility & Cancellation

Most car suppliers offer penalty-free cancellations, so you don’t have to worry about losing money if your plans change. To cancel your booking log into your account through the Trips portal. Click manage booking and cancel this car. If you needed to alter your booking, then you can create a new one once you have canceled.

We all love being rewarded

One Key members save 10% or more on select hotels, cars, activities and vacation rentals. Not only that, earn OneKeyCash for every dollar spent on eligible hotels, vacation rentals, flights, car rentals, and more when you book across our family of brands: Expedia, Hotels.com and VRBO. Learn more and join today.

Car classes available from Expedia in 2026

The classes of vehicles available will change depending on your chosen location.

• Compact car rentals    
• Convertible car rentals    
• Economy car rentals    
• Fullsize car rentals    
• Luxury car rentals
• Midsize car rentals    
• Mini car rentals    
• Minivan rentals    
• Pickup car rentals    
• Premium car rentals
• Sportscar rentals    
• Standard car rentals    
• SUV rentals    
• Van rentals