Title: Top Independent in Central, SC - Expedia.com [Central Travel Guide](https://expedia.com/Central.dx10503)[Hotels in Central](https://expedia.com/Central-Hotels.d10503.Travel-Guide-Hotels)[Vacation Rentals in Central](https://expedia.com/Central-Vacation-Rentals.d10503.Travel-Guide-VacationRentals)[Flights to Central](https://expedia.com/Cheap-Flights-To-Central.d10503.Travel-Guide-Flights)[Car Rentals in Central](https://expedia.com/Car-Rentals-In-Central.d10503.Car-Rental-Guide)[Central Vacation Packages](https://expedia.com/Central.d10503.Destination-Travel-Guides) ![Todd Creek Falls](https://images.trvl-media.com/place/10503/baefe116-5881-466e-b320-6ded2828ee1d.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/10503/baefe116-5881-466e-b320-6ded2828ee1d.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check prices for these dates Tonight [Mar 29 - Mar 30](https://www.expedia.com/Hotel-Search?regionId=10503&startDate=2026-03-29&endDate=2026-03-30&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Mar 30 - Mar 31](https://www.expedia.com/Hotel-Search?regionId=10503&startDate=2026-03-30&endDate=2026-03-31&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Apr 3 - Apr 5](https://www.expedia.com/Hotel-Search?regionId=10503&startDate=2026-04-03&endDate=2026-04-05&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) In two weeks [Apr 10 - Apr 12](https://www.expedia.com/Hotel-Search?regionId=10503&startDate=2026-04-10&endDate=2026-04-12&adults=2&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2FCentral-Hotels-Independent.0-0-d10503--bIndependent.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2FCentral-Hotels-Independent.0-0-d10503--bIndependent.Travel-Guide-Filter-Hotels) ## Top Central Hotel Reviews ![Quality Inn & Suites Easley - Greenville](https://images.trvl-media.com/lodging/1000000/30000/24700/24698/94758a40_y.jpg) ### Quality Inn & Suites Easley - Greenville 10/10 Excellent "Clean rooms " [](https://expedia.com/Easley-Hotels-Quality-Inn-Suites.h24698.Hotel-Information) ![Days Inn by Wyndham Anderson](https://images.trvl-media.com/lodging/1000000/10000/6400/6344/bea0c9d1_y.jpg) ### Days Inn by Wyndham Anderson 10/10 Excellent "Awesome place " [](https://expedia.com/Anderson-Hotels-Days-Inn-By-Wyndham-Anderson.h6344.Hotel-Information) ![The Shepherd Hotel Downtown Clemson](https://images.trvl-media.com/lodging/88000000/87690000/87688200/87688155/bd45b45c_y.jpg) ### The Shepherd Hotel Downtown Clemson 10/10 Excellent "If I can get a room? I will always stay here. 😍" [](https://expedia.com/Clemson-Hotels-The-Shepherd-Hotel-Downtown-Clemson.h87688155.Hotel-Information) ![Quality Inn Clemson near University](https://images.trvl-media.com/lodging/1000000/10000/2600/2544/269fcec4_y.jpg) ### Quality Inn Clemson near University 10/10 Excellent "Clean room " [](https://expedia.com/Anderson-Hotels-Quality-Inn-Clemson-Near-University.h2544.Hotel-Information) ![Hampton Inn & Suites Seneca-Clemson Area](https://images.trvl-media.com/lodging/7000000/6700000/6696900/6696886/8f736b3a_y.jpg) ### Hampton Inn & Suites Seneca-Clemson Area 10/10 Excellent "Everything was great. " [](https://expedia.com/Anderson-Hotels-Hampton-Inn-Suites-Seneca-Clemson-Area.h6696886.Hotel-Information) ![Clemson University's James F. Martin Inn](https://images.trvl-media.com/lodging/9000000/8480000/8475000/8474950/ad943919_y.jpg) ### Clemson University's James F. Martin Inn 10/10 Excellent "Always a great stop on our travels! Enjoy the walking space golf and restaurants on site!" [](https://expedia.com/Anderson-Hotels-Clemson-Universitys-James-F-Martin-Inn.h8474950.Hotel-Information) ![Woodspring Suites Anderson North I-85](https://images.trvl-media.com/lodging/115000000/114350000/114348700/114348655/220e9886_y.jpg) ### Woodspring Suites Anderson North I-85 6/10 Okay "Pet fee is misleading in the website for $10 per stay per night. But the actual cost is $50 for the 1st night. " [](https://expedia.com/Anderson-Hotels-Woodspring-Suites-Anderson-North-I-85.h114348655.Hotel-Information) ![The Abernathy of Clemson](https://images.trvl-media.com/lodging/18000000/17230000/17229400/17229377/ead974b7_y.jpg) ### The Abernathy of Clemson 8/10 Good "Parking is free and couldn't be more convenient. Come and go as you please even on the day we checked out. Super friendly staff. Bartender (new?) has great local knowledge and is awesome. " [](https://expedia.com/Anderson-Hotels-The-Abernathy-Of-Clemson.h17229377.Hotel-Information) ![Inn @ Clemson](https://images.trvl-media.com/lodging/1000000/90000/84700/84636/d257793d_y.jpg) ### Inn @ Clemson 8/10 Good "Hotel has been updated and was very clean. Check-in was quick and staff friendly. Our charging plugs kept falling out of the outlets and wouldn’t charge. And breakfast, although fresh, was limited. It absolutely worked for us, as we just needed a place to sleep comfortably. 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