Find spa resorts & hotels in Cross Key Waterways, Key Largo from $298

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Check availability on Cross Key Waterways Resorts & Hotels with Spas

Our top choices for Cross Key Waterways hotels with a spa

Reefhouse Resort & Marina

Reefhouse Resort & Marina
3.5 star property
Key Largo
9.2 out of 10, Wonderful, (1332)
"Nice hotel with great staff."
United States
David
$269 nightly
The price is $298
Dec 14 - Dec 15
Total with taxes and fees
Reefhouse Resort & Marina

Playa Largo Resort & Spa, Autograph Collection

Playa Largo Resort & Spa, Autograph Collection
4.5 star property
Rock Harbor
8.8 out of 10, Excellent, (1000)
"Beautiful location, great views, very clean property, room was great (great bed), friendly staff."
United States
Scott
$378 nightly
The price is $425
Dec 15 - Dec 16
Total with taxes and fees
Playa Largo Resort & Spa, Autograph Collection

Kona Kai Resort and Gallery - Adults Only

Kona Kai Resort and Gallery - Adults Only
2.5 star property
Rock Harbor
9.8 out of 10, Exceptional, (293)
"The Kona Kai Resort was perfect for us. We especially appreciated the small resort with quiet spaces to relax, read and admire the view. "
United States
Bastianella
$344 nightly
The price is $387
Dec 14 - Dec 15
Total with taxes and fees
Kona Kai Resort and Gallery - Adults Only

Premium Floating Bungalow by Stay Ombi

Premium Floating Bungalow by Stay Ombi
3.5 star property
Key Largo
$1,259 nightly
The price is $1,417
Jan 1 - Jan 2, 2026
Total with taxes and fees
Premium Floating Bungalow by Stay Ombi
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find out more about Cross Key Waterways

Top Cross Key Waterways attractions for a relaxing vacation

In the Cross Key Waterways neighborhood, travelers seeking a pampering escape can indulge in both relaxation and adventure. Start your day with a rejuvenating treatment at a local spa, where expert therapists use organic products to ensure a revitalizing experience. Afterward, explore the serene waters of the nearby Key Waterways Park, perfect for a peaceful nature walk or a family-friendly picnic under the shade of lush trees. For those looking to unleash their adventurous spirit, kayaking through the calm waterways offers a unique perspective of the natural beauty surrounding the area. As the sun sets, enjoy a delightful dining experience at a waterfront restaurant, where you can savor fresh seafood while gazing at the stunning views. Finally, retreat to your hotel, where spacious rooms equipped with luxurious amenities await you. Many hotels in the area feature private balconies overlooking the water, and attentive staff are dedicated to ensuring your family feels pampered throughout your stay. With such a blend of relaxation and exploration, your time in Cross Key Waterways promises to be memorable.

Top Cross Key Waterways Hotel Reviews

Frequently asked questions

Looking for a spa hotel in Cross Key Waterways?
Book one of our fantastic spa hotels and pamper yourself from the moment you arrive. Hotels with spas are a great way to take a break from your routine and add a layer of luxury to your vacation.
What's there to see and do in Cross Key Waterways?
Enjoy Cross Key Waterways with a stop at Caribbean Club Bar, John Pennekamp Coral Reef State Park, and Jimmy Johnson's Big Chill. If you have some spare time during your trip, you might want to check out Harry Harris Park and Florida Keys Dive Center.
What is a Cross Key Waterways spa hotel?
Spa hotels in Cross Key Waterways provide lodging and have a full on-site spa which offers services such as massages and body treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation.

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