Title: The Best 5 Star Hotels in Key Largo, FL from $560 | Expedia.com [Key Largo Travel Guide](https://expedia.com/Key-Largo.dx8369)[Hotels in Key Largo](https://expedia.com/Key-Largo-Hotels.d8369.Travel-Guide-Hotels)[Vacation Rentals in Key Largo](https://expedia.com/Key-Largo-Vacation-Rentals.d8369.Travel-Guide-VacationRentals)[Flights to Key Largo](https://expedia.com/Cheap-Flights-To-Key-Largo.d8369.Travel-Guide-Flights)[Things to do in Key Largo](https://expedia.com/Things-To-Do-In-Key-Largo.d8369.Travel-Guide-Activities)[Car Rentals in Key Largo](https://expedia.com/Car-Rentals-In-Key-Largo.d8369.Car-Rental-Guide)[Key Largo Vacation Packages](https://expedia.com/Key-Largo.d8369.Destination-Travel-Guides) ![Key Largo](https://images.trvl-media.com/place/8369/5e0b4233-e04b-457e-97e7-e5f79e3c6a6f.jpg?impolicy=fcrop&w=1200&h=500&q=medium) ![](https://images.trvl-media.com/place/8369/5e0b4233-e04b-457e-97e7-e5f79e3c6a6f.jpg?impolicy=fcrop&w=1200&h=500&q=medium) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__price_find.svg) ### Upfront pricing Our total price for your stay includes taxes and fees - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__deals.svg) ### Treat yourself Save 10% or more on over 100,000 hotels worldwide with Member Prices [Learn about One Key](https://www.expedia.com/welcome-one-key) - ![](https://a.travel-assets.com/travel-assets-manager/pictogram-bex/light__bed.svg) ### Be picky Search almost a million properties worldwide ## Check availability on Key Largo 5 Star Hotels Tonight [Feb 19 - Feb 20](https://www.expedia.com/Hotel-Search?regionId=8369&startDate=2026-02-19&endDate=2026-02-20&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Tomorrow [Feb 20 - Feb 21](https://www.expedia.com/Hotel-Search?regionId=8369&startDate=2026-02-20&endDate=2026-02-21&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) This weekend [Feb 20 - Feb 22](https://www.expedia.com/Hotel-Search?regionId=8369&startDate=2026-02-20&endDate=2026-02-22&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) Next weekend [Feb 27 - Mar 1](https://www.expedia.com/Hotel-Search?regionId=8369&startDate=2026-02-27&endDate=2026-03-01&adults=2&star=50&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true) ## Our top choices for Key Largo 5-star hotels ![Exterior](https://images.trvl-media.com/lodging/94000000/93070000/93061400/93061348/ab76abc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/94000000/93070000/93061400/93061348/2c922f43.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Outdoor pool](https://images.trvl-media.com/lodging/94000000/93070000/93061400/93061348/9b3c41b7.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![55-inch Smart TV with cable channels, TV, Netflix](https://images.trvl-media.com/lodging/94000000/93070000/93061400/93061348/f4aac8d9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Condo in the Keys [](https://www.expedia.com/Tavernier-Hotels-Condo-In-The-Keys.h93061348.Hotel-Information) Tavernier 8.0/10 Very Good (13 reviews) "Love the location " ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Angela [](https://www.expedia.com/Tavernier-Hotels-Condo-In-The-Keys.h93061348.Hotel-Information) ![Terrace/patio](https://images.trvl-media.com/lodging/110000000/109730000/109724500/109724487/71ae5bc4.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Design Villa, Canal View | Dining room](https://images.trvl-media.com/lodging/110000000/109730000/109724500/109724487/d702e54d.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Exterior](https://images.trvl-media.com/lodging/110000000/109730000/109724500/109724487/w1024h1021x0y3-63c47ce9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ![Design Villa, Canal View | Living area | 75-inch Smart TV with digital channels, Netflix, streaming services](https://images.trvl-media.com/lodging/110000000/109730000/109724500/109724487/8c99be49.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium) ### Waterfront House with Boat Dock [](https://www.expedia.com/Tavernier-Hotels-Waterfront-House-With-Boat-Dock.h109724487.Hotel-Information) Hammer Point 6.0/10 (3 reviews) "Everything was fine except half way through the stay the water department came and shut off the water at the street. It came back on a few hours later, so it all worked out. The house was fine" ![United States](https://a.travel-assets.com/egds/marks/flags/us.svg) Philip J [](https://www.expedia.com/Tavernier-Hotels-Waterfront-House-With-Boat-Dock.h109724487.Hotel-Information) ![](https://a.travel-assets.com/pricing-claim/sparkle_dark.svg) Save an average of 15% on thousands of hotels when you're signed in [Sign in ](https://expedia.com/user/signin?ckoflag=0&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Key-Largo-Hotels.s50-0-d8369.Travel-Guide-Filter-Hotels)[ Sign up, it's free ](https://expedia.com/signup?enable_registration=true&+=&uurl=e3id%3Dredr%26rurl%3D%2F5Star-Key-Largo-Hotels.s50-0-d8369.Travel-Guide-Filter-Hotels) ## Explore similar 4-star hotels Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Key Largo. ![Baker's Cay Resort Key Largo, Curio Collection by Hilton](https://images.trvl-media.com/lodging/1000000/20000/14100/14042/bbdba544_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Baker's Cay Resort Key Largo, Curio Collection by Hilton 97000 Overseas Hwy Key Largo FL $582 nightly $655 total Mar 5 - Mar 6 Total with taxes and fees 8.6/10 Excellent! (1,003 reviews) [](https://expedia.com/Key-Largo-Hotels-Bakers-Cay-Resort-Key-Largo.h14042.Hotel-Information) ![Playa Largo Resort & Spa, Autograph Collection](https://images.trvl-media.com/lodging/12000000/11920000/11919100/11919055/489feb58_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Playa Largo Resort & Spa, Autograph Collection 97450 Overseas Highway Key Largo FL $498 nightly $560 total Feb 25 - Feb 26 Total with taxes and fees 8.8/10 Excellent! (1,000 reviews) [](https://expedia.com/Key-Largo-Hotels-Playa-Largo-Resort-Spa.h11919055.Hotel-Information) ![Lime Key by Florida Keys Luxury Rentals](https://images.trvl-media.com/lodging/73000000/72290000/72284400/72284316/c89ab9c7_y.jpg?impolicy=resizecrop&rw=402&ra=fit) ### Lime Key by Florida Keys Luxury Rentals 25 N. Bounty Lane Key Largo FL [Get rates](https://expedia.com/Hotel-Search?startDate=3%2F5%2F2026&endDate=3%2F6%2F2026&selected=72284316&PinnedHotelID=72284316&HadPinnedHotel=true®ionId=8369) [](https://expedia.com/Key-Largo-Hotels-Lime-Key-By-Florida-Keys-Luxury-Rentals.h72284316.Hotel-Information) Still don't see what you're looking for? [See all properties in Key Largo.](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F20%2F2026&endDate=2%2F21%2F2026®ionId=8369&star=50) You can also use these popular filters to refine your search. [Pool](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F20%2F2026&endDate=2%2F21%2F2026®ionId=8369&star=50&star=50&amenities=POOL)[Spa](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F20%2F2026&endDate=2%2F21%2F2026®ionId=8369&star=50&star=50&amenities=SPA_ON_SITE)[Hot tub](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F20%2F2026&endDate=2%2F21%2F2026®ionId=8369&star=50&star=50&amenities=HOT_TUB)[Breakfast included](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F20%2F2026&endDate=2%2F21%2F2026®ionId=8369&star=50&star=50&amenities=FREE_BREAKFAST)[Waterpark](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.Hotel&startDate=2%2F20%2F2026&endDate=2%2F21%2F2026®ionId=8369&star=50&star=50&amenities=WATER_PARK) Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply. ## Learn more about Key Largo The underwater paradise of John Pennekamp Coral Reef State Park offers the best snorkeling visibility before noon. Dive among colorful fish at America's first undersea park, then feast on fresh-caught grouper at waterfront restaurants where locals gather. [See all hotels in Key Largo](https://www.expedia.com/Hotel-Search?startDate=2026-03-05&endDate=2026-03-06&adults=2®ionId=8369) ![Key Largo](https://images.trvl-media.com/place/8369/5e0b4233-e04b-457e-97e7-e5f79e3c6a6f.jpg?impolicy=fcrop&w=900&h=506&p=1&q=high) ## Top Key Largo Hotel Reviews ## Find out more about Key Largo There's nothing wrong with enjoying the finer things in life. Why not request complete opulence during your trip to Key Largo? There's no reason to delay a getaway to Key Largo any longer. You'll join the multitudes of vacationers who have made Key Largo so fashionable in the last year. The hotels in Key Largo also offer great customer service, averaging 3.9 in our ranking system, setting you up for a truly relaxing getaway. Don't wait any longer. Our 5-star hotels in Key Largo are the perfect places to relax in during your next chunk of time off. ### Get a Great Deal on 5-Star Hotels in Key Largo You can expect high quality from your hotel. Spa treatments, delicious meals, and one-on-one attention are all at your fingertips. You're sure to find exactly the accommodation you need. You'll be pleased to note that the hotels in Key Largo offer great customer service, averaging 3.9 in our ranking system, so you know you're in good hands. How do you want to relax? A full-body massage to help your cares fall away? A concierge to help you plan every detail of your day? Fluffy down pillows, delectable chocolate desserts, and even space for your family pet in some cases...these hotels are one-of-a-kind. But you aren't going to spend your entire vacation in your room, of course. We hear you. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what you end up doing, the 5-star hotels in Key Largo are the perfect place to relax after a busy day. Ready to learn more? Then explore the 798 reviews various guests have left on Expedia and get to know these places. ### Make Your Escape The results are in, and Key Largo 5-star hotels are the place to be when you book your next vacation. Many visitors recommend a trip to this location, so don't wait any longer. Expedia can help you land a great deal on accommodation. Don't put off your dream vacation any longer. Opt for one of our Key Largo 5-star hotels today and soothe yourself in the lap of luxury tomorrow. ## Frequently asked questions ### How much does it cost to stay in a 5-star hotel in Key Largo? > - Search for the lowest price per night from $560 ### What makes a hotel 5 stars in Key Largo? ### Are there any 5-star all-inclusive resorts in Key Largo? ## Explore a world of travel with Expedia - Lodging - Flights - Packages - Cars - Vacation Rentals - Other - [Hotels near Jimmy Johnson's Big Chill ](https://www.expedia.com/Jimmy-Johnsons-Big-Chill-Hotels.0-l553248621563219632-0.Travel-Guide-Filter-Hotels) - [Hotels near Jacob's Aquatic Center ](https://www.expedia.com/Jacobs-Aquatic-Center-Hotels.0-l553248621532652370-0.Travel-Guide-Filter-Hotels) - [Hotels near Key Largo Park ](https://www.expedia.com/Key-Largo-Park-Key-Largo-Hotels.0-n553248635976481780-0.Travel-Guide-Filter-Hotels) - [Hotels near Pirates Cove ](https://www.expedia.com/Pirates-Cove-Key-Largo-Hotels.0-n553248635976468554-0.Travel-Guide-Filter-Hotels) - 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[Hotels near Indian Waterways ](https://www.expedia.com/Indian-Waterways-Tavernier-Hotels.0-n553248635976468854-0.Travel-Guide-Filter-Hotels) - [Flights to Miami ](https://www.expedia.com/Cheap-Flights-To-Miami.d178286.Travel-Guide-Flights) - [Flights to Tavernier ](https://www.expedia.com/Cheap-Flights-To-Tavernier.d10047.Travel-Guide-Flights) - [Flights from Tavernier ](https://www.expedia.com/lp/flights/10047/flights-from-tavernier) - [Jimmy Johnson's Big Chill ](https://www.expedia.com/Jimmy-Johnsons-Big-Chill-Key-Largo.d553248621563219632.Vacation-Attraction) - [Jacob's Aquatic Center ](https://www.expedia.com/Jacobs-Aquatic-Center-Key-Largo.d553248621532652370.Vacation-Attraction) - [Visit Pirates Cove ](https://www.expedia.com/Key-Largo-Pirates-Cove.dx553248635976468554) - [Bluefin Rock Harbor Marina ](https://www.expedia.com/Bluefin-Rock-Harbor-Marina-Key-Largo.d6249260.Vacation-Attraction) - [Baker's Cay Resort Beach ](https://www.expedia.com/Bakers-Cay-Resort-Beach-Key-Largo.d715323874527461376.Vacation-Attraction) - [Marinelab Undersea Laboratory ](https://www.expedia.com/MarineLab-Undersea-Laboratory-Key-Largo.d6069275.Vacation-Attraction) - [Visit Anglers Park ](https://www.expedia.com/Key-Largo-Anglers-Park.dx553248635976468912) - [Anglers Park Vacations ](https://www.expedia.com/Anglers-Park.d553248635976468912.Destination-Travel-Guides) - [Caribbean Club Bar ](https://www.expedia.com/Caribbean-Club-Bar-Key-Largo.d553248621533115829.Vacation-Attraction) - [Pigeon Key ](https://www.expedia.com/Pigeon-Key-Tavernier.d553248621563219631.Vacation-Attraction) - [Harry Harris Park ](https://www.expedia.com/Harry-Harris-Park-Tavernier.d553248621533115827.Vacation-Attraction) - [Kiffney's Firearms and Indoor Range ](https://www.expedia.com/Kiffneys-Firearms-And-Indoor-Range-Key-Largo.d553248621532652376.Vacation-Attraction) - [Florida Keys Visitor Center - Key Largo ](https://www.expedia.com/Florida-Keys-Visitor-Center-Key-Largo.d553248621561884504.Vacation-Attraction) - [Key Largo Baptist Church ](https://www.expedia.com/Key-Largo-Baptist-Church-Key-Largo.d553248621532652377.Vacation-Attraction) - 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