Santo Spirito

Florence

Santo Spirito
Santo Spirito
Santo Spirito
Santo Spirito
Panoramic view of Florence at sunset with in the background, the Basilica di Santo Spirito and its spire, the Church of San Frediano in Cestello and Ponte Vecchio.

Popular places to visit

Things to do


Santo Spirito Hotel Deals

Hotel Horto Convento

Hotel Horto Convento

4 out of 5
Viale Ariosto, 13 Florence FI
$278 nightly
The price is $323 total per night from Apr 30 to May 1
$323 total
Apr 30 - May 1
Total with taxes and fees
Stay at this hotel in Florence. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.8/10 Exceptional! (645 reviews)
Great hotel all around and great breakfast. Highly recommend and will go back when in Florence

Reviewed on Apr 19, 2026

Hotel Horto Convento
Palazzo Mannaioni Suites

Palazzo Mannaioni Suites

4 out of 5
Via Maffia 9 - 17r Florence FI
$173 nightly
The price is $207 total per night from Apr 30 to May 1
$207 total
Apr 30 - May 1
Total with taxes and fees
Stay at this residence in Florence. Enjoy free WiFi, concierge services, and premium bedding. Our guests praise the helpful staff in our reviews. Popular attractions ...
9.2/10 Wonderful! (1,104 reviews)
Great location,it was close to a lot of restaurants and shops, it was clean and we had a balcony. We could see the church’s bell tower which it sounded really loud but it didn’t bother us since we were up by 8:30am. But if you like to sleep in it will wake you up because it’s pretty loud. Other than ...

Reviewed on Apr 28, 2026

Palazzo Mannaioni Suites
La Torre Del Cestello

La Torre Del Cestello

Via Borgo San Frediano, 8 Florence FI
$152 nightly
The price is $184 total per night from May 4 to May 5
$184 total
May 4 - May 5
Total with taxes and fees
Stay at this residence in Florence. Enjoy free WiFi, valet parking (surcharge), and daily housekeeping. Popular attractions Ponte Vecchio and Uffizi Gallery ...
9/10 Wonderful! (250 reviews)
The room was not at all as shown. The hotel lobby isn’t a lobby but a small room with a check in desk on the 3 floor. There is only a few rooms. This is not a hotel. The cafe/bar on the lower level is loud with extremely loud music and they go until 4 am. We could not sleep. The main chandelier in ...

Reviewed on Apr 20, 2026

La Torre Del Cestello
UNA Hotels Vittoria Firenze

UNA Hotels Vittoria Firenze

4 out of 5
Via Pisana 59 Florence FI
$157 nightly
The price is $189 total per night from May 24 to May 25
$189 total
May 24 - May 25
Total with taxes and fees
Book a stay at this boutique hotel in Florence. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (1,000 reviews)
Helpful staff. Vey good breakfast. Clean and comfortable room.

Reviewed on Apr 1, 2026

UNA Hotels Vittoria Firenze
Foresteria Valdese di Firenze - Casa per Ferie

Foresteria Valdese di Firenze - Casa per Ferie

Via dei Serragli 49 Florence FI
$113 nightly
The price is $138 total per night from May 11 to May 12
$138 total
May 11 - May 12
Total with taxes and fees
Stay at this guesthouse in Florence. Enjoy free WiFi, 2 meeting rooms, and satellite TV channels. Our guests praise the helpful staff and the clean rooms in ...
8.8/10 Excellent! (204 reviews)
The staff was amazing.

Reviewed on Apr 10, 2026

Foresteria Valdese di Firenze - Casa per Ferie
Residenza D'Epoca Al Numero 8

Residenza D'Epoca Al Numero 8

Via Borgo San Frediano n. 8 Florence FI
$154 nightly
The price is $185 total per night from May 4 to May 5
$185 total
May 4 - May 5
Total with taxes and fees
Stay at this B&B in Florence. Enjoy free WiFi, valet parking (surcharge), and daily housekeeping. Our guests praise the helpful staff in our reviews. Popular ...
9/10 Wonderful! (153 reviews)
great location and customer service was excellent.. little bit hard to find but ask restaurant on same street and they will tell you where it is exactly.

Reviewed on Apr 25, 2026

Residenza D'Epoca Al Numero 8
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other neighborhoods around Santo Spirito

San Frediano

San Frediano

San Frediano is popular for its stunning river views, and if you're looking for more to see and do, you might think about a trip to Piazza Santo Spirito or Santo Spirito Basilica.

San Frediano
Oltrarno

Oltrarno

4.5/5(538 area reviews)

South of the River Arno, this quarter boasts part of Florence's historic center, featuring notable sites like Santo Spirito di Firenze, Palazzo Pitti, Belvedere, and Piazzale Michelangelo.

Oltrarno
Santa Maria Novella

Santa Maria Novella

4.5/5(1,073 area reviews)

Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.

Santa Maria Novella
San Giovanni

San Giovanni

If you're spending some time in San Giovanni, Uffizi Gallery and Cathedral of Santa Maria del Fiore are top sights worth seeing.

San Giovanni
Historic Centre of Florence

Historic Centre of Florence

Known for its fascinating museums, stunning cathedral, and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Cathedral of Santa Maria del Fiore and Uffizi Gallery are major draws. Catch the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city.

Historic Centre of Florence
Duomo

Duomo

5/5(2,242 area reviews)

Cathedral of Santa Maria del Fiore and Uffizi Gallery are just a few worthwhile attractions to visit in Duomo. Travelers also love the fascinating museums, stunning cathedral, and popular shops.

Duomo


Santo Spirito

Choose one or more items to build your trip:

Explore a world of travel with Expedia