Santo Spirito

Florence

Province of Florence showing interior views, heritage elements and a church or cathedral
Province of Florence showing interior views, heritage elements and a church or cathedral
Province of Florence which includes a bridge, night scenes and a river or creek
Province of Florence featuring markets and street scenes
Province of Florence featuring heritage architecture and a church or cathedral

Popular places to visit

Florence, Italy - Basilica di Santo Spirito, Tuscany religious architecture

Piazza Santo Spirito

5/5(1 review)

Learn about the local history of Florence with a stop at Piazza Santo Spirito. Discover the fascinating museums and notable monuments in this vibrant area.

Piazza Santo Spirito
Ancient Roman gate into the old city of Florence, Italy. Porta Romana or Porta San Pier Gattolino

Porta Romana

4/5(14 reviews)

Porta Romana is just one of the places to see in Arcetri, so why not enjoy the other things to explore during your travels? Discover the acclaimed art scene and stunning cathedral in this vibrant area.

Porta Romana
Brancacci Chapel which includes heritage architecture and a church or cathedral

Brancacci Chapel

A dazzling array of Renaissance frescoes adorn the walls of the most famous chapel of Florence’s 750-year-old Church of Santa Maria del Carmine.

Brancacci Chapel

Santo Spirito Basilica

5/5(1 review)

Learn about the local history of Florence when you spend time at Santo Spirito Basilica. Stroll along the riverfront or visit the churches in this vibrant area.

Santo Spirito Basilica

Piazza del Carmine

5/5(1 review)

You can learn about the history of Florence with a stop at Piazza del Carmine. Amble around this vibrant area's riverfront or experience its acclaimed art scene.

Piazza del Carmine

Torrigiani Garden

Explore the great outdoors at Torrigiani Garden, a lovely green space in Florence. Stroll along the riverfront or visit the stunning cathedral in this vibrant area.

Torrigiani Garden

Things to do

Skip-the-Line Duomo: Priority-Access 30-Minute Guided Tour

Skip-the-Line Florence Duomo: Priority-Access Express Guided Tour

$26
per adult
80% of travellers recommend
Skip-the-Line Florence Duomo: Priority-Access Express Guided Tour
Micheal Angelo's David

Skip the Line: Florence's Accademia Gallery Priority Entrance Ticket

$37
per adult
86% of travellers recommend
Skip the Line: Florence's Accademia Gallery Priority Entrance Ticket
Tuscany Experience In Pisa, Siena, San Gimignano & Chianti

Tuscany Experience In Pisa, Siena, San Gimignano & Chianti

$101
per adult
92% of travellers recommend
Tuscany Experience In Pisa, Siena, San Gimignano & Chianti
Florence half day combo tour with David, Uffizi & Duomo

Florence Half Day Tour with Michelangelo’s David, Accademia & Uffizi Option

$33
per adult
92% of travellers recommend
Florence Half Day Tour with Michelangelo’s David, Accademia & Uffizi Option
Skip the line: Uffizi and Accademia Small Group Walking Tour

Uffizi & Accademia Timed Entry: Small Group Duomo Walking Tour

$50
per adult
98% of travellers recommend
Uffizi & Accademia Timed Entry: Small Group Duomo Walking Tour
Uffizi Gallery Small-Group Guided Tour with Skip-the-Line

Uffizi Gallery: Small Group Guided Tour or Reserved Entry Ticket

$50
per adult
86% of travellers recommend
Uffizi Gallery: Small Group Guided Tour or Reserved Entry Ticket
See all activities in Florence

Santo Spirito Hotel Deals

Hotel Horto Convento

Hotel Horto Convento

4 out of 5
Viale Ariosto, 13 Florence FI
$98 nightly
The price is $125 total per night from Mar 8 to Mar 9
$125 total
Mar 8 - Mar 9
Total with taxes and fees
Stay at this hotel in Florence. Enjoy free breakfast, free WiFi, and room service. Our guests praise the breakfast and the helpful staff in our reviews. Popular ...
9.8/10 Exceptional! (624 reviews)
It was a nice, clean and quiet hotel.

Reviewed on Mar 1, 2026

Hotel Horto Convento
Palazzo Mannaioni Suites

Palazzo Mannaioni Suites

4 out of 5
Via Maffia 9 - 17r Florence FI
$104 nightly
The price is $131 total per night from Mar 4 to Mar 5
$131 total
Mar 4 - Mar 5
Total with taxes and fees
Stay at this residence in Florence. Enjoy free WiFi, concierge services, and satellite TV channels. Our guests praise the helpful staff in our reviews. Popular ...
9.2/10 Wonderful! (1,088 reviews)
Beautiful room, very thorough check in with a very nice man who gave us great dining recommendations. We loved having a big fridge. The shower was a bit small but overall we really enjoyed the room.

Reviewed on Feb 26, 2026

Palazzo Mannaioni Suites
UNA Hotels Vittoria Firenze

UNA Hotels Vittoria Firenze

4 out of 5
Via Pisana 59 Florence FI
$112 nightly
The price is $140 total per night from Mar 29 to Mar 30
$140 total
Mar 29 - Mar 30
Total with taxes and fees
Book a stay at this boutique hotel in Florence. Enjoy free WiFi, breakfast (surcharge), and room service. Our guests praise the helpful staff in our reviews. ...
8.4/10 Very Good! (1,000 reviews)
Perfect stay! Not only was the check-in smooth, but everything else was also satisfying. The breakfast was delicious, the staff were friendly, and the location was ideal. There wasn't a single thing I didn't like. I’ll definitely be back!

Reviewed on Jan 1, 2026

UNA Hotels Vittoria Firenze
La Torre Del Cestello

La Torre Del Cestello

Via Borgo San Frediano, 8 Florence FI
$82 nightly
The price is $107 total per night from Mar 4 to Mar 5
$107 total
Mar 4 - Mar 5
Total with taxes and fees
Stay at this residence in Florence. Enjoy free WiFi, valet parking (surcharge), and daily housekeeping. Popular attractions Pitti Palace and Ponte Vecchio are ...
9/10 Wonderful! (238 reviews)
Personal je velmi pratelsky, neni co vytknout. Ubytovani je v super lokalite, kousek od hlavnich památek . Postel velmi pohodlna, koupelna prostorna .

Reviewed on Feb 25, 2026

La Torre Del Cestello
Foresteria Valdese di Firenze - Casa per Ferie

Foresteria Valdese di Firenze - Casa per Ferie

Via dei Serragli 49 Florence FI
$105 nightly
The price is $130 total per night from Mar 10 to Mar 11
$130 total
Mar 10 - Mar 11
Total with taxes and fees
Stay at this property in Florence. Enjoy free WiFi, 2 meeting rooms, and satellite TV channels. Our guests praise the helpful staff and the clean rooms in our ...
8.8/10 Excellent! (197 reviews)
Room was very dated, old and cold. Shower seemed particularly dirty and the water was cold. Of the 9 hotels we have stayed in on our travels thus far this was the only 3 star that on this site rated 4.4. Good location. Lovely staff. Wouldn’t stay again.

Reviewed on Jan 2, 2026

Foresteria Valdese di Firenze - Casa per Ferie
Casa Santo Nome di Gesù

Casa Santo Nome di Gesù

Piazza del Carmine, 21 Florence FI
$108 nightly
The price is $133 total per night from Mar 5 to Mar 6
$133 total
Mar 5 - Mar 6
Total with taxes and fees
Stay at this guesthouse in Florence. Enjoy free breakfast, free WiFi, and parking (surcharge). Our guests praise the helpful staff in our reviews. Popular attractions ...
8.8/10 Excellent! (344 reviews)
Pretty neat place. Run by nuns. Great building. Friendly staff Breakfast included. Rooms simple clean. Beautiful location. Would definitely go back.

Reviewed on Jan 28, 2026

Casa Santo Nome di Gesù
See all 495 properties in Santo Spirito
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

The Annual Vacation Sale

Members save up to 40% on hotels and homes. Plan this year’s big trip and save.
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Other neighborhoods around Santo Spirito

Brancacci Chapel which includes a church or cathedral and heritage architecture

San Frediano

San Frediano is popular for its stunning river views, and if you're looking for more to see and do, you might think about a trip to Piazza Santo Spirito or Boboli Gardens.

San Frediano
Arcetri which includes a river or creek, a sunset and a bridge

Oltrarno

4.5/5(529 area reviews)

South of the River Arno, this quarter boasts part of Florence's historic center, featuring notable sites like Santo Spirito di Firenze, Palazzo Pitti, Belvedere, and Piazzale Michelangelo.

Oltrarno
Santa Maria Novella which includes heritage architecture, a church or cathedral and street scenes

Santa Maria Novella

4.5/5(1,057 area reviews)

Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.

Santa Maria Novella
Ponte Vecchio showing a bridge and a river or creek

San Giovanni

If you're spending some time in San Giovanni, Cathedral of Santa Maria del Fiore and Piazza della Repubblica are top sights worth seeing.

San Giovanni
Arcetri showing a bridge and a river or creek

Historic Centre of Florence

Cathedral of Santa Maria del Fiore and Piazza di Santa Maria Novella are a few top attractions in Historic Centre of Florence. Hop around the city on the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop and check out the area's fascinating museums, stunning cathedral, and stunning river views.

Historic Centre of Florence
Duomo featuring heritage architecture and street scenes as well as a small group of people

Duomo

5/5(2,214 area reviews)

Cathedral of Santa Maria del Fiore and Piazza di Santa Maria Novella are just a few worthwhile attractions to visit in Duomo. Travelers also love the fascinating museums, stunning cathedral, and popular shops.

Duomo
See our Where To Stay guide

Santo Spirito

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