Santo Spirito
Florence
Visit Santo Spirito
Popular places to visit
Piazza Santo Spirito
Learn about the local history of Florence with a stop at Piazza Santo Spirito. Discover the fascinating museums and stunning cathedral in this vibrant area.
Porta Romana
Find out about the history of Arcetri when you take a trip to Porta Romana. Amble around this vibrant area's riverfront or experience its fascinating museums.
Brancacci Chapel
A dazzling array of Renaissance frescoes adorn the walls of the most famous chapel of Florence’s 750-year-old Church of Santa Maria del Carmine.
Santo Spirito Basilica
Learn about the local history of Florence when you spend time at Santo Spirito Basilica. Stroll along the riverfront or visit the churches in this vibrant area.
Torrigiani Garden
Explore the great outdoors at Torrigiani Garden, a lovely green space in Florence. Stroll along the riverfront or visit the stunning cathedral in this vibrant area.
Santa Maria della Carmine
You can learn about the history of Florence with a visit to Santa Maria della Carmine. Visit the notable monuments and stunning cathedral in this vibrant area.
Things to do
Skip-the-Line Florence Duomo: Priority-Access Express Guided Tour
Skip the Line: Florence's Accademia Gallery Priority Entrance Ticket
Tuscany Experience In Pisa, Siena, San Gimignano & Chianti
Florence Half Day Tour with Uffizi, Michelangelo’s David & Accademia
E-bike Adventure To Fiesole From Florence With Olive Oil Tasting
Pisa and Piazza dei Miracoli Half Day Tour from Florence
Santo Spirito Hotel Deals
Hotel Horto Convento
A lovely property in a convenient location. You can walk to any attraction in Florence, and at the end of the day, the hotel is hidden away in a walled courtyard.
Reviewed on Jan 4, 2026
Palazzo Mannaioni Suites
Staff, location, and the apartment were all 10/10! Novella welcomed us at the property. She was incredibly friendly, very informative, and gave us great recommendations for things to do and places to eat. The flat was spotless and very well set up. Additional towels were provided, and we really appreciated ...
Reviewed on Jan 6, 2026
UNA Hotels Vittoria Firenze
Perfect stay! Not only was the check-in smooth, but everything else was also satisfying. The breakfast was delicious, the staff were friendly, and the location was ideal. There wasn't a single thing I didn't like. I’ll definitely be back!
Reviewed on Jan 1, 2026
La Torre Del Cestello
Beautiful place to stay. Just outside of the bustle but walking within distance. Warmly welcomed and staff were lovely.
Reviewed on Dec 25, 2025
Oltrarno Splendid
Rooms are very comfy and super quiet... Great bedding. Love the eclectic decor, as well. Staff is extremely friendly and helpful. I highly recommend this hotel.
Reviewed on Jan 5, 2026
Casa Santo Nome di Gesù
Really a nice place, like the room style and good for family stay!
Reviewed on Jan 1, 2026
Other neighborhoods around Santo Spirito
San Frediano
San Frediano is popular for its stunning river views, and if you're looking for more to see and do, you might think about a trip to Piazza Santo Spirito or Boboli Gardens.
Oltrarno
South of the River Arno, this quarter boasts part of Florence's historic center, featuring notable sites like Santo Spirito di Firenze, Palazzo Pitti, Belvedere, and Piazzale Michelangelo.
Santa Maria Novella
Enjoy the popular shops in Santa Maria Novella. Piazza di Santa Maria Novella is a worthwhile stop, and you can jump on the metro at Porta al Prato - Leopolda Tram Stop or Fratelli Rosselli Tram Stop to see more of Porta al Prato.
San Giovanni
If you're spending some time in San Giovanni, Piazza della Repubblica and Via de' Calzaiuoli are top sights worth seeing.
Historic Centre of Florence
Known for its fascinating museums, stunning cathedral, and stunning river views, there's plenty to explore in Historic Centre of Florence. Top attractions like Piazza di Santa Maria Novella and Via de' Calzaiuoli are major draws. Catch the metro at Unità Tram Stop or Valfonda - Stazione Santa Maria Novella Tram Stop to see more of the city.
Duomo
Piazza di Santa Maria Novella and Via de' Calzaiuoli are just a few worthwhile attractions to visit in Duomo. Travelers also love the fascinating museums, stunning cathedral, and popular shops.
Santo Spirito
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- Visit San Frediano
- Piazza del Carmine
- Brancacci Chapel
- Torrigiani Garden
- Pitti Palace
- Visit Oltrarno
- Chiesa di Ognissanti
- Accademia Italiana
- Via Maggio
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- Leopolda Station Exhibition Center
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- Visit Santa Maria Novella
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- Visit Florence
- Ponte Vecchio
- Visit Tuscany
- Strozzi Palace
- Basilica of Santa Maria Novella
- Visit Province of Florence
- Palazzo Antinori
- Visit Duomo
- Palazzo Davanzati Museum
- Province of Florence Vacations
- Visit Porta al Prato
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- Loggia del Mercato Nuovo
- Piazza della Repubblica
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