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Our top choices for Mayo hotels

University Inn

University Inn
2.5 star property
Shelby
8.6 out of 10, Excellent, (468 reviews)
"The room was very quiet and clean the staff were very nice and friendly "
United States
Theresa
$105 nightly
The price is $118
May 29 - May 30
Total with taxes and fees
University Inn

Studio 6 – Spindale, NC – Forest City

Studio 6 – Spindale, NC – Forest City
2.0 star property
Spindale
$54 nightly
The price is $61
May 5 - May 6
Total with taxes and fees
Studio 6 – Spindale, NC – Forest City

Motel 6 Spartanburg, Sc – Northwest / Business 85

Motel 6 Spartanburg, Sc – Northwest / Business 85
2.0 star property
Spartanburg
7.6 out of 10, Good, (111 reviews)
"Good place to stay "
United States
Anthony
$61 nightly
The price is $68
May 3 - May 4
Total with taxes and fees
Motel 6 Spartanburg, Sc – Northwest / Business 85

Baymont by Wyndham Gaffney

Baymont by Wyndham Gaffney
2.5 star property
Gaffney
7.4 out of 10, Good, (688 reviews)
"Rooms are okay not spacious enough andd water could get a lttle hotter . Staff was nice. Its parking was able to park right infront of my room door. "
United States
Karin
$66 nightly
The price is $73
May 10 - May 11
Total with taxes and fees
Baymont by Wyndham Gaffney

Quality Inn Gaffney I-85

Quality Inn Gaffney I-85
2.5 star property
Gaffney
7.6 out of 10, Good, (397 reviews)
"No issues with breakfast. Room was nice, clean and comfortable, wasn't looking for the tajmahal, something close to where I was going to be, lots of good food choices "
United States
Calvin
$56 nightly
The price is $63
May 29 - May 30
Total with taxes and fees
Quality Inn Gaffney I-85

Holiday Inn Express Gaffney by IHG

Holiday Inn Express Gaffney by IHG
2.5 star property
Gaffney
8.8 out of 10, Excellent, (479 reviews)
"Room very clean staff was great breakfast was really good with lots of options "
United States
melvin
$83 nightly
The price is $90
May 10 - May 11
Total with taxes and fees
Holiday Inn Express Gaffney by IHG

Hampton Inn Gaffney

Hampton Inn Gaffney
2.5 star property
Gaffney
8.8 out of 10, Excellent, (707 reviews)
"Would stay again breakfast was amazing "
United States
Theresa
$83 nightly
The price is $91
May 31 - Jun 1
Total with taxes and fees
Hampton Inn Gaffney

Econo Lodge Forest City

Econo Lodge Forest City
2.0 star property
Forest City
7.2 out of 10, Good, (393 reviews)
"Good quality of service and clean rooms very safe for family stay."
United States
Yogesh
$63 nightly
The price is $71
May 17 - May 18
Total with taxes and fees
Econo Lodge Forest City

USA Economy Lodge

USA Economy Lodge
2.0 star property
Spartanburg
7.8 out of 10, Good, (99 reviews)
"It's clean but the staff is to strict "
United States
Olufemi
$60 nightly
The price is $66
May 20 - May 21
Total with taxes and fees
USA Economy Lodge

Quality Inn Forest City

Quality Inn Forest City
2.5 star property
Forest City
7.6 out of 10, Good, (321 reviews)
"Staff was friendly and the room was clean. "
United States
Danielle
$71 nightly
The price is $81
May 25 - May 26
Total with taxes and fees
Quality Inn Forest City

Red Roof Inn Gaffney

Red Roof Inn Gaffney
2.0 star property
Gaffney
7.2 out of 10, Good, (444 reviews)
"Clean room friendly staff"
United States
Melissa
$66 nightly
The price is $74
May 9 - May 10
Total with taxes and fees
Red Roof Inn Gaffney

Sleep Inn Gaffney at I-85

Sleep Inn Gaffney at I-85
2.5 star property
Gaffney
7.6 out of 10, Good, (341 reviews)
"Ladies at check in and out were awesome."
United States
Robert
$71 nightly
The price is $80
May 10 - May 11
Total with taxes and fees
Sleep Inn Gaffney at I-85

Days Inn by Wyndham Spartanburg

Days Inn by Wyndham Spartanburg
2.0 star property
Boiling Springs
7.6 out of 10, Good, (154 reviews)
"Awesome stay. The staff and service was excellent!"
United States
Reginald
$77 nightly
The price is $85
May 7 - May 8
Total with taxes and fees
Days Inn by Wyndham Spartanburg

Baymont by Wyndham Forest City

Baymont by Wyndham Forest City
2.5 star property
Forest City
7.4 out of 10, Good, (732 reviews)
"Only issue I had was the coffee maker in my room did not work (I honestly didn't think to report it, I was there to attend a funeral and my mind was all over the place). I went to the breakfast area in search of coffee to find there was no coffee there either. I went to a fast food place nearby to get my morning coffee."
United States
Pamela
$64 nightly
The price is $72
May 10 - May 11
Total with taxes and fees
Baymont by Wyndham Forest City

Quality Inn Duncan - Spartanburg West

Quality Inn Duncan - Spartanburg West
2.5 star property
Duncan
7.8 out of 10, Good, (383 reviews)
"Everything was perfect "
United States
Michelle
$66 nightly
The price is $73
Jun 1 - Jun 2
Total with taxes and fees
Quality Inn Duncan - Spartanburg West

SUN AND SAND MOTEL

SUN AND SAND MOTEL
2.0 star property
Spartanburg
7.6 out of 10, Good, (24 reviews)
"Great location "
United States
Tracy
$60 nightly
The price is $66
May 31 - Jun 1
Total with taxes and fees
SUN AND SAND MOTEL

Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

Holiday Inn Express Hotel & Suites Spartanburg-North by IHG
2.5 star property
Spartanburg
8.6 out of 10, Excellent, (908 reviews)
"Very friendly staff"
United States
Katie
$90 nightly
The price is $100
May 10 - May 11
Total with taxes and fees
Holiday Inn Express Hotel & Suites Spartanburg-North by IHG

Econo Lodge Gaffney

Econo Lodge Gaffney
2.0 star property
Gaffney
6.8 out of 10, (146 reviews)
"Good experience"
United States
Alisha
$55 nightly
The price is $61
May 16 - May 17
Total with taxes and fees
Econo Lodge Gaffney

Super 8 by Wyndham Gaffney

Super 8 by Wyndham Gaffney
2.0 star property
Gaffney
6.8 out of 10, (215 reviews)
"Okay place to stay overnight "
United States
Lori
$57 nightly
The price is $64
Jun 1 - Jun 2
Total with taxes and fees
Super 8 by Wyndham Gaffney

Hampton Inn Spartanburg-North I-85

Hampton Inn Spartanburg-North I-85
2.5 star property
Spartanburg
8.6 out of 10, Excellent, (1,000 reviews)
"Staff was great, very easy check in. Hotel is a little difficult to find at night. Very convenient to I 85. If you plan on visiting Greer or Greenville there are much closer properties, we were further out than we thought going by the on line description. all in all a fine, clean hotel"
United States
PAUL
$84 nightly
The price is $93
May 10 - May 11
Total with taxes and fees
Hampton Inn Spartanburg-North I-85
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Top Mayo Hotel Reviews

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Hotels in Mayo with star-rating

Frequently asked questions

What is the best area to stay in Mayo?
The best area to stay in Mayo is the town center, particularly around Main Street, as it offers the most convenience for visitors.

This central area of Mayo is where you'll find the majority of local businesses, including eateries and shops. It's a compact and walkable district, making it easy to access amenities. The town hall and the local library are also situated here, providing a central point for navigation.

For solo travelers or couples, staying in the town center provides easy access to local dining and any community events that might be happening.
When is the best time to go to Mayo?
The best time to visit Mayo, South Carolina, is during the spring (April to June) and fall (September to November) months.

During these periods, the weather is pleasantly mild, with comfortable temperatures and lower humidity, making it ideal for outdoor activities and exploring the local area without the intense heat of summer. You'll find many local events and festivals taking place, offering a great way to experience the community's culture.

For travelers looking for a relaxed experience, these seasons offer peaceful surroundings.
Can I cancel my hotel reservation on Expedia?
You can cancel your hotel reservation on Expedia, though it depends on the cancellation policy of your booking. Most bookings are refundable if canceled within 24-48 hours of the scheduled arrival. Be sure to check your booking confirmation for the exact cancellation policy. If free cancellation is available, you can cancel directly through your Expedia account by logging in, going to "My Trips", and selecting your reservation. To find flexible deals, filter your search by "Fully refundable property" for hotels in Mayo.
How can I save on a Mayo hotel booking with Expedia?
With Expedia, you earn OneKeyCash™* on eligible Mayo hotel bookings for every dollar you spend – just join our One Key™ travel rewards program to get started. It's free to join, and you'll unlock our lowest Member Prices as soon as you're signed in. On top of this, you could also save significantly by bundling your hotel and flights together on Expedia.

*Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Mayo hotel?
Prices for hotels in Mayo often vary, but you can find a great deal from $62 on Expedia. All sorts of factors affect price, such as the time of year or the days of the week you choose for your stay. Find the best deals by being flexible with your dates, and sort search results by "Price: low to high" for the cheapest rate.

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