Find Resorts & Hotels with Spas in Pickens, SC

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Top Pickens Resorts & Hotels with Spas

Hotel Domestique

4.0 star property
Travelers Rest
9.6 out of 10, Exceptional, (30)
"Overall it was an exceptional experience and would highly recommend to anyone looking for a quiet get away."
United States
Chuck
$325 nightly
The price is $358
Jan 1 - Jan 2, 2026
Total with taxes and fees
Hotel Domestique

Greystone Inn

3.5 star property
Lake Toxaway
9.4 out of 10, Exceptional, (85)
"Most beautiful quiet and peaceful old guest home. "
Canada
Tanya
$279 nightly
The price is $312
Dec 7 - Dec 8
Total with taxes and fees
Greystone Inn

Grand Bohemian Lodge Greenville, Autograph Collection

4.0 star property
Greenville Downtown
9.6 out of 10, Exceptional, (413)
"The staff were really sweet and responsive. The views from the rooms are breathtaking! "
United States
Krystal
$295 nightly
The price is $324
Jan 4 - Jan 5, 2026
Total with taxes and fees
Grand Bohemian Lodge Greenville, Autograph Collection
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find out more about Pickens

Top Pickens attractions for a relaxing vacation

Pickens, South Carolina, offers a tranquil escape for travelers seeking spa hotel experiences nestled in nature. Start your journey at the nearby Table Rock State Park, where scenic hiking trails lead you to breathtaking views and serene landscapes, perfect for unwinding after a day of pampering. Another must-visit is the charming downtown area, where local boutiques and artisanal shops provide a taste of Southern culture, allowing you to explore unique finds. For those interested in golf, the nearby Pickens Country Club offers a delightful course for both beginners and seasoned players, ensuring a fun day in the sun. Don’t miss a visit to the historic Hagood Mill, where you can experience live music and crafts, bringing a sense of local heritage into your relaxing getaway. After a day of exploration, retreat to one of the area's hotels that feature spa services, where attentive staff will cater to your every need, ensuring you feel thoroughly pampered. The perfect blend of outdoor adventure and luxurious relaxation awaits you in Pickens.

Top Pickens Hotel Reviews

Frequently asked questions

Looking for a spa hotel in Pickens?
Soothe the senses with some time in one of our wonderful spa hotels. Check out the natural parks in Pickens - worth a picture or two! Hotels with spas are the perfect way to take a break from your daily routine and add a layer of luxury to your vacation.
What's there to see and do in Pickens?
Experience Pickens and visit Table Rock State Park, Table Rock, and Lake Keowee. If you have a little extra time during your trip, you might want to check out Irma Morris Museum of Fine Arts and Hagood Mill Historic Site.
What is a Pickens spa hotel?
Spa hotels in Pickens provide lodging and have an on-site spa offering services such as massages and body treatments. Some also offer in-room treatments. Spa hotels are ideal if you are looking for some R&R during your vacation.

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