Name: Hotel Museo Spa Casa Santo Domingo
Price range: $320 total
Rating: 9.2

Barceló Guatemala City

7 Avenida 15-45, Zona 9 Guatemala City Guatemala

$108 nightly

$132 total

May 20 - May 21

Total with taxes and fees

Book a stay at this luxury hotel in Guatemala City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the breakfast and the pool in our ...

9.2/10 Wonderful! (3,314 reviews)

Arrived extra early and hotel was able to provide an earlier check in than expected.

Reviewed on May 4, 2026

Tikal Futura Hotel & Convention Center

Calzada Roosevelt 22-43 Guatemala City Guatemala

$112 nightly

$137 total

May 17 - May 18

Total with taxes and fees

Book a stay at this luxury hotel in Guatemala City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. ...

9.2/10 Wonderful! (1,011 reviews)

Great food, rooms are clean!!

Reviewed on May 5, 2026

Hotel Museo Spa Casa Santo Domingo

3a Calle Oriente No 28 A Antigua Guatemala Sacatepequez

Fully refundableReserve now, pay when you stay

$262 nightly

$320 total

May 10 - May 11

Total with taxes and fees

Book a stay at this luxury hotel in Antigua Guatemala. Enjoy free parking, a full-service spa, and 2 restaurants. Our guests praise the helpful staff and the ...

9.2/10 Wonderful! (1,059 reviews)

Most of the staff at reception is friendly except for Andrea Camargo she is not friendly at all.The hotel is the best in Antigua it has everything you need.

Reviewed on May 5, 2026

See all 1,253 properties in San Mateo Milpas Altas

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cabañas Casa Realeza

Cam. a Hobbitenango Antigua Guatemala Sacatepéquez

Stay at this cabin in Antigua Guatemala. Enjoy free WiFi, free parking, and daily housekeeping. Popular attractions Casa Santo Domingo Museum and Central Park ...

All Suite El Marques de Antigua

4 ave. South No. 30 Antigua Guatemala Sacatepequez

Stay at this aparthotel in Antigua Guatemala. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. Popular ...

9.4/10 Exceptional! (361 reviews)

Excellent hotel, it is truly a home away from home. I loved the details in the decoration, the architecture, the privacy. It is also in a quiet part of Antigua, yet, you can walk to retaurants and shops.

Reviewed on May 4, 2026

Suites Terraza Imperial

15 Ave. A 4-39 Zona 13 Guatemala City Guatemala

Stay at this aparthotel in Guatemala City. Enjoy free WiFi, free parking, and a fitness center. Popular attractions Paseo Cayala and El Obelisco are located ...

9/10 Wonderful! (330 reviews)

Excelente

Reviewed on May 1, 2026

See all properties in San Mateo Milpas Altas

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Antigua Guatemala Cathedral

4.5/5(427 reviews)

After visiting Antigua Guatemala Cathedral, make a plan to see the other sights and activities in Antigua Guatemala. Discover the area's volcano viewpoints, or seek out its local tours.

Central Park

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Enjoy the volcano viewpoints and explore Central Park, a lovely green space in Antigua Guatemala. Discover the area's shops, or seek out its local tours.

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Find out about the history of Antigua Guatemala when you spend time at Santa Catalina Arch. Discover the volcano viewpoints and shops in this romantic area.

Traditional vase and jar at market in Antigua, Guatemala.

Antigua Market

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During your trip to Antigua Guatemala, you can enjoy retail therapy at Antigua Market. Discover the volcano viewpoints in this romantic area, or enjoy its local tours.

La Merced Church

4.5/5(303 reviews)

After visiting La Merced Church, make a plan to see the other sights and activities in Antigua Guatemala. Discover the area's shops, or seek out its local tours.

Cerro de La Cruz

4.5/5(5 reviews)

You can find out about the history of Antigua Guatemala when you stop by Cerro de La Cruz. Discover the area's volcano viewpoints, or seek out its local tours.