Name: Hotel Museo Spa Casa Santo Domingo
Price range: $311 total
Rating: 9.2

Barceló Guatemala City

7 Avenida 15-45, Zona 9 Guatemala City Guatemala

$110 nightly

$134 total

May 10 - May 11

Total with taxes and fees

Book a stay at this luxury hotel in Guatemala City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the breakfast and the pool in our ...

9.2/10 Wonderful! (3,304 reviews)

Great place to stay in Central Guatemala City. Close to the airport and the shuttle is part of their customer service. Don’t miss the morning buffet, it is incredible.

Reviewed on May 2, 2026

Tikal Futura Hotel & Convention Center

Calzada Roosevelt 22-43 Guatemala City Guatemala

$112 nightly

$137 total

May 3 - May 4

Total with taxes and fees

Book a stay at this luxury hotel in Guatemala City. Enjoy free WiFi, free parking, and a full-service spa. Our guests praise the helpful staff in our reviews. ...

9.2/10 Wonderful! (1,005 reviews)

Very Nice, Wonderful people, clean environment

Reviewed on May 2, 2026

Hotel Museo Spa Casa Santo Domingo

3a Calle Oriente No 28 A Antigua Guatemala Sacatepequez

Fully refundableReserve now, pay when you stay

$254 nightly

$311 total

May 12 - May 13

Total with taxes and fees

Book a stay at this luxury hotel in Antigua Guatemala. Enjoy free parking, a full-service spa, and 2 restaurants. Our guests praise the helpful staff and the ...

9.2/10 Wonderful! (1,056 reviews)

Liked the room and the pool

Reviewed on May 2, 2026

See all 1,253 properties in San Mateo Milpas Altas

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cabañas Casa Realeza

Cam. a Hobbitenango Antigua Guatemala Sacatepéquez

Stay at this cabin in Antigua Guatemala. Enjoy free WiFi, free parking, and daily housekeeping. Popular attractions Casa Santo Domingo Museum and Central Park ...

All Suite El Marques de Antigua

4 ave. South No. 30 Antigua Guatemala Sacatepequez

Stay at this aparthotel in Antigua Guatemala. Enjoy free WiFi, free parking, and breakfast (surcharge). Our guests praise the helpful staff in our reviews. Popular ...

9.4/10 Exceptional! (359 reviews)

Everything was great!

Reviewed on Apr 30, 2026

Suites Terraza Imperial

15 Ave. A 4-39 Zona 13 Guatemala City Guatemala

Stay at this aparthotel in Guatemala City. Enjoy free WiFi, free parking, and a fitness center. Popular attractions Paseo Cayala and El Obelisco are located ...

9/10 Wonderful! (330 reviews)

Excelente

Reviewed on May 1, 2026

See all properties in San Mateo Milpas Altas

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Check San Mateo Milpas Altas hotel availability

Popular places to visit

Antigua Guatemala Cathedral

After visiting Antigua Guatemala Cathedral, make a plan to see the other sights and activities in Antigua Guatemala. Discover the area's volcano viewpoints, or seek out its local tours.

Central Park

Enjoy the volcano viewpoints and explore Central Park, a lovely green space in Antigua Guatemala. Discover the area's shops, or seek out its local tours.

Santa Catalina Arch

Find out about the history of Antigua Guatemala when you spend time at Santa Catalina Arch. Discover the volcano viewpoints and shops in this romantic area.

Traditional vase and jar at market in Antigua, Guatemala.

Antigua Market

During your trip to Antigua Guatemala, you can enjoy retail therapy at Antigua Market. Discover the volcano viewpoints in this romantic area, or enjoy its local tours.

La Merced Church

After visiting La Merced Church, make a plan to see the other sights and activities in Antigua Guatemala. Discover the area's shops, or seek out its local tours.

Cerro de La Cruz

You can find out about the history of Antigua Guatemala when you stop by Cerro de La Cruz. Discover the area's volcano viewpoints, or seek out its local tours.