Southern Indiana

Travel Guide

Kentucky Center for the Performing Arts featuring modern architecture
Belle of Louisville featuring a bay or harbor and a ferry as well as a small group of people
Louisville Slugger Museum showing interior views
Belle of Louisville showing a ferry and a bay or harbor as well as a small group of people
Frazier International History Museum which includes interior views
Hoosier traditions add a unique slant to your trip to the towns of this region, while the forest offers a serene spot for a picnic beside old buffalo grounds.

Visit Southern Indiana to discover a region with proud traditions and a varied topography. Its cities are known for the famous Hoosier culture, while Hoosier National Forest is among the leafy preserves that show off the area’s scenic hills and valleys. Travel through the southern part of this Midwestern state for insights into its exceptional culture and terrain.

Arrive in the largest city in the region, Evansville, for a sense of local culture. Bring the kids to the Mesker Park Zoo & Botanic Garden, before watching a game of baseball at Bosse Field. This is one of the oldest baseball arenas in the U.S., having been inaugurated in 1915. Check out the USS LST Ship Memorial docked along the Ohio River, taking a look around what is the last fully operational World War II Landing Ship in the country.

For less urban activities, explore Hoosier National Forest. Set out on trails meandering up and down the park’s hills or try horseback riding, fishing or camping.

Follow the Buffalo Trace route across the southern part of the state. Long before major settlements, buffalo and Native American people lived in these areas. Find information at the Falls of the Ohio State Park in Clarksville. Marengo Cave and Patoka Lake State Park offer other outdoor adventures.

Plan an eclectic family trip to French Lick, with casinos and spas for adults and the French Lick Scenic Railway for kids of any age. Purchase candy from one of the country’s oldest family-owned candy companies in Jeffersonville and visit an Amish village in Montgomery.

Southern Indiana is separated from Kentucky by the Ohio River. Arrive at Indianapolis International Airport and drive south for 165 miles (265 kilometers) to reach Evansville in less than 3 hours. Louisville, Kentucky, is just across the river. Explore the surroundings for nearby cities such as Cincinnati, Lexington and Nashville across state borders. The region has a distinctive Hoosier culture, as well as a varied and picturesque topography.

Where to stay in Southern Indiana

Louisville Science Center featuring outdoor art

West Main Historic District

Boasting the largest collection of cast iron façades outside New York's SoHo district, this historic area features "Museum Row" with attractions like the Louisville Slugger Museum and Muhammad Ali Center.

West Main Historic District
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Downtown Evansville

Dive into the cultural hub of Evansville, where you can catch a performance by the Evansville Philharmonic Orchestra at Victory Theatre or explore the Children's Museum of Evansville. Don't miss the LST-325 Museum and Ford Center nearby!

Downtown Evansville
Cute Gastropub in downtown Louisville. The Burger had a pickled tomator on the bottom, I could have eaten a whole plate of those! #FoodieFinds

Portland

While visiting Portland, you might make a stop by sights like Portland Museum and Lannan Park Trailhead.

Portland
Whiteside Bakery built in 1908, later incorporated into the General Baking Co produced Bond Bread, a favorite of Hopalong Cassidy.

California

If you're spending some time in California, Ohio River Valley and Union Station are top sights worth seeing.

California
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Shawnee

Though Shawnee might not have many top sights, you can venture to the surrounding area to see attractions like Frazier International History Museum and Louisville Slugger Museum.

Shawnee
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Russell

If you're spending some time in Russell, Ohio River Valley and I. Willis Cole Residence are top sights worth seeing.

Russell
Radisson Hotel Louisville North

Radisson Hotel Louisville North

3 out of 5
505 Marriott Drive Clarksville IN
$67 nightly
The price is $76 total per night from Dec 14 to Dec 15
$76 total
Dec 14 - Dec 15
Total with taxes and fees
Book a stay at this business-friendly hotel in Clarksville. Enjoy free WiFi, free parking, and an outdoor pool. Our guests praise the clean rooms in our reviews. ...
6.8/10 (2,571 reviews)
Clean room, great staff. We enjoyed our stay.

Reviewed on Nov 30, 2025

Radisson Hotel Louisville North
Hilton Garden Inn Jeffersonville Louisville North

Hilton Garden Inn Jeffersonville Louisville North

3 out of 5
4900 Water Tower Road Jeffersonville IN
$103 nightly
The price is $117 total per night from Dec 14 to Dec 15
$117 total
Dec 14 - Dec 15
Total with taxes and fees
Book a stay at this business-friendly hotel in Jeffersonville. Enjoy free parking, breakfast (surcharge), and a 24-hour fitness center. Our guests praise the ...
9.4/10 Exceptional! (394 reviews)
Room was clean and quiet.

Reviewed on Nov 28, 2025

Hilton Garden Inn Jeffersonville Louisville North
Hyatt Place Evansville

Hyatt Place Evansville

3 out of 5
202 Se 2nd St Evansville IN
Fully refundableReserve now, pay when you stay
$122 nightly
The price is $141 total per night from Dec 11 to Dec 12
$141 total
Dec 11 - Dec 12
Total with taxes and fees
Book a stay at this business-friendly hotel in Evansville. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the breakfast and the helpful ...
9.4/10 Exceptional! (1,020 reviews)
Very clean. Great food

Reviewed on Nov 29, 2025

Hyatt Place Evansville
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
The Villas at French Lick Springs

The Villas at French Lick Springs

3 out of 5
8718 W State Road 56 French Lick IN
Stay at this condo in French Lick. Enjoy free WiFi, free parking, and a fitness center. Our guests praise the helpful staff in our reviews. Popular attractions ...
8.8/10 Excellent! (275 reviews)
Villa was clean, but outdated. It was very quiet with no noise from adjoining villas. Location is good and area excellent. Good value and would stop there again

Reviewed on Nov 18, 2025

The Villas at French Lick Springs
Derby Time Riverside Cabin

Derby Time Riverside Cabin

Derby IN
Stay at this cabin in Derby. Enjoy free WiFi, a garden, and laundry facilities.
10/10 Exceptional! (133 reviews)
We all loved staying in this beautiful cabin. Very peaceful, enjoying the fire pit while watching the river traffic. Great view of the river even from inside the cabin. And, it is conveniently located to the nearby restaurant and store in Derby.

Reviewed on Nov 30, 2025

Derby Time Riverside Cabin
John's cabin

John's cabin

French Lick IN
Stay at this cabin in French Lick. Enjoy free WiFi, a garden, and an in-room coffeemaker. Popular attractions French Lick Springs Hotel and French Lick Casino ...
9.8/10 Exceptional! (60 reviews)
The host was very accommodating. If we had any complaints it would have to be the cabin was smaller than we thought it was going to be. But everything else was nice. Would possibly rent again with smaller group.

Reviewed on Nov 24, 2025

John's cabin
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Popular places to visit

Cities near Southern Indiana

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