Southern Minnesota Vacation Rentals

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Vacation Rentals in Southern Minnesota

The Berkman
Terrace/patio
The Berkman
3.0 star property
9.6 out of 10, Exceptional, (215)
"We had a short stay, but the convenience to walking across the street to the Mayo Hospital was definitely a bonus. Everything you need is right there, a restaurant or a few groceries from the pantry to cook yourself in the full kitchen! Very nice place, we highly recommend!"
The price is $199
$231 total
includes taxes & fees
Jun 21 - Jun 22
The Berkman
Broadway Plaza, Trademark Collection by Wyndham
Fridge, microwave, oven, stovetop
Broadway Plaza, Trademark Collection by Wyndham
3.0 star property
9.2 out of 10, Wonderful, (136)
"We loved the space!"
The price is $152
$234 total
includes taxes & fees
Jul 5 - Jul 6
Broadway Plaza, Trademark Collection by Wyndham
Charming Cottage in Stockholm, WI on Lake Pepin and the Scenic Great River Road
Terrace/patio
Charming Cottage in Stockholm, WI on Lake Pepin and the Scenic Great River Road
9.4 out of 10, Exceptional, (35)
"My bridal party and I stayed here the weekend of my wedding. It was the perfect place for us to stay. Plenty of places for us to get ready. We loved the outdoor patio and the location was perfect."
Charming Cottage in Stockholm, WI on Lake Pepin and the Scenic Great River Road
Heritage hideaway-Secluded Log Cabin
Exterior
Heritage hideaway-Secluded Log Cabin
10.0 out of 10, Exceptional, (330)
"We enjoyed our stay. Road bikes on the rr trail. Very peaceful stay."
Heritage hideaway-Secluded Log Cabin
Creekside Cabin Getaway
Property grounds
Creekside Cabin Getaway
9.4 out of 10, Exceptional, (95)
"I absolutely loved my stay, the property was fantastic and Winona is a beautiful place. I was by myself for some solitude and the creekside cabins get away was a great fit."
Creekside Cabin Getaway
Century Cottage-PERFECT for Mayo & downtown visitors!
Outdoor dining
Century Cottage-PERFECT for Mayo & downtown visitors!
10.0 out of 10, Exceptional, (85)
"Nice house Mary was an awesome host!"
Century Cottage-PERFECT for Mayo & downtown visitors!
Root River Valley Cabin ~ Lanesboro, MN
Exterior
Root River Valley Cabin ~ Lanesboro, MN
10.0 out of 10, Exceptional, (262)
"Spacious home, with lots of little sitting areas for everyone to have quiet time on their own. We enjoyed being walking distance from the Root River Trail. Short drive to Lanesboro where there was plenty to do.We were lucky to be in Lanesboro for the Rhubarb Festival, which was enjoyed by all. We also went to the The Mane Theatre for an excellent satire, "The Outsider". Thank you for letting us stay in your beautiful home."
Root River Valley Cabin ~ Lanesboro, MN
Cozy, modern 2 bedroom with laundry,+ walk to mayo
Terrace/patio
Cozy, modern 2 bedroom with laundry,+ walk to mayo
9.4 out of 10, Exceptional, (6)
"Awesome host’s with great communication. The home is very comfortable, must be okay with stairs. Clean, great beds, open feel with good lighting and windows throughout. Love the front porch. All appliances in working order, stocked kitchen, solid internet. Just shy of a mile walk downtown or too Main Clinic buildings. Close to river walk, felt safe. Good neighborhood. Would definitely recommend"
Cozy, modern 2 bedroom with laundry,+ walk to mayo
The Dollar House - Between the Lakes!
Private kitchen | Fridge, microwave, oven, stovetop
The Dollar House - Between the Lakes!
10.0 out of 10, Exceptional, (15)
"Great value for a single or couple. Cozy older place that has been nicely updated. Excellent shower and bed. Host is very responsive and accommodating."
The Dollar House - Between the Lakes!
The Perfect Family Get Away !
Exterior
The Perfect Family Get Away !
9.6 out of 10, Exceptional, (109)
"We were attending a wedding in the area so we’re looking for a VRBO for us and several family members to stay. This is a gem of a place for families to enjoy- inside and out! We loved sitting on the back patio watching the sunset, as well as hanging out on the large sectional in the living room enjoying the view. Would be great for a longer stay- I just wish we had more than a weekend wedding planned. Joe and Nancy are great hosts."
The Perfect Family Get Away !
Mayo Discount Offered-Family-Friendly 2 Level-Near Mayo
Interior
Mayo Discount Offered-Family-Friendly 2 Level-Near Mayo
8.6 out of 10, Excellent, (16)
"Just keep in mind that the property is very old and so are all the appliances and furniture. When I say old, I mean clawfoot bathtub old. It’s not bad- they all seem to work fine- I just wasn’t expecting that based on the pictures. The house is also set up pretty weird and there are a lot of stairs so keep that in mind if you have mobility issues. Other than that, can’t complain. The place is very clean. The renters seem very nice. There was a moment in which the water needed to be temporarily...
Mayo Discount Offered-Family-Friendly 2 Level-Near Mayo
Happy Days Log Home and garden on Fountain Lake. Toys for all!
Property grounds
Happy Days Log Home and garden on Fountain Lake. Toys for all!
10.0 out of 10, Exceptional, (23)
"Absolutely beautiful would not change one thing only that wish we would have had more time"
Happy Days Log Home and garden on Fountain Lake. Toys for all!
Oasis Luxe Suite—Steps from Mayo Clinic Hospital
Private kitchen | Fridge, microwave, oven, stovetop
Oasis Luxe Suite—Steps from Mayo Clinic Hospital
10.0 out of 10, Exceptional, (8)
"This accommodation was perfect for us. Location was so close to St Marys and let cal restaurants. Shuttle to Mayo worked out well. Well supplied. Can opener needs to be replaced and you need a church key. Extremely clean and comfortable."
Oasis Luxe Suite—Steps from Mayo Clinic Hospital
St. Augustine Mint House GARAGE!!
Microwave, dishwasher, coffee/tea maker, cookware/dishes/utensils
St. Augustine Mint House GARAGE!!
10.0 out of 10, Exceptional, (52)
"Nice “get away” place. Clean and cozy."
St. Augustine Mint House GARAGE!!
Charming 2-Bedroom house along city trail 1 mile from Mayo Clinic and downtown.
Property grounds
Charming 2-Bedroom house along city trail 1 mile from Mayo Clinic and downtown.
9.8 out of 10, Exceptional, (34)
"We were very pleased with having this house to return to every day. We were here for Dr. Appointments for 1 month and this was perfect. It had everything we could have wanted or needed. We loved the trails right outside the door that can take you all over the city. Great location and very nice neighborhood."
Charming 2-Bedroom house along city trail 1 mile from Mayo Clinic and downtown.
Civic Center, River Front, WALK to Mayo Clinic!! GARAGE Parking!
Private kitchen | Fridge, microwave, oven, stovetop
Civic Center, River Front, WALK to Mayo Clinic!! GARAGE Parking!
10.0 out of 10, Exceptional, (85)
"This home is a perfect find for anyone staying in Rochester, particularly conducive to Mayo visits. The home is well maintained with great views and an easy walking vicinity to many attractions."
The price is $84
$216 total
includes taxes & fees
Jun 15 - Jun 16
Civic Center, River Front, WALK to Mayo Clinic!! GARAGE Parking!
Charming Rochester Home - 2 Mi to Mayo Clinic!
TV, foosball
Charming Rochester Home - 2 Mi to Mayo Clinic!
9.8 out of 10, Exceptional, (12)
"I stayed here with my kids while I was working overnights, they were entertained and felt safe."
Charming Rochester Home - 2 Mi to Mayo Clinic!
Walking distance of all amenities of Lanesboro! Bike the trail~ float the river
Exterior
Walking distance of all amenities of Lanesboro! Bike the trail~ float the river
Walking distance of all amenities of Lanesboro! Bike the trail~ float the river
Holiday Haus. (sleeps 8+)
Fridge, microwave, oven, stovetop
Holiday Haus. (sleeps 8+)
10.0 out of 10, Exceptional, (89)
"The house is lovely, the outside spaces are fantastic, the location is terrific. We had a wonderful time and would definitely recommend."
Holiday Haus. (sleeps 8+)
Adorable house in lower north
Exterior
Adorable house in lower north
Adorable house in lower north
Don't see what you're looking for?
See all available properties in Southern Minnesota
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Southern Minnesota Vacation Rental Travel Info

Vacation rentals
69
Popular accommodation
Southern Minnesota private vacation homes
International airport
Minneapolis, MN (MSP-Minneapolis - St. Paul Intl.)

Other types of properties in Southern Minnesota you may be interested in

Kahler Grand Hotel
Indoor pool
Kahler Grand Hotel
3.0 star property
8.2 out of 10, Very Good, (1005)
"Always stay here"
The price is $139
$161 total
includes taxes & fees
Jun 27 - Jun 28
Kahler Grand Hotel
Kahler Inn and Suites - Mayo Clinic Area
Aerial view
Kahler Inn and Suites - Mayo Clinic Area
3.5 star property
7.6 out of 10, Good, (1220)
"Liked the old way with free breakfast "
The price is $108
$125 total
includes taxes & fees
Jun 28 - Jun 29
Kahler Inn and Suites - Mayo Clinic Area
Hyatt House Rochester/Mayo Clinic Area
Terrace/patio
Hyatt House Rochester/Mayo Clinic Area
3.0 star property
9.0 out of 10, Wonderful, (575)
"Very clean facility and friendly staff! Excellent location for the Mayo Clinic and surrounding restaurants!"
The price is $114
$131 total
includes taxes & fees
Jun 29 - Jun 30
Hyatt House Rochester/Mayo Clinic Area
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Everything you need to know about Southern Minnesota vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Southern Minnesota vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Southern Minnesota vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Southern Minnesota vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Southern Minnesota. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Southern Minnesota in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $84 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Southern Minnesota rentals

At Expedia, we put the best Southern Minnesota vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Southern Minnesota rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Southern Minnesota vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Southern Minnesota. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

Recent reviews of Southern Minnesota properties
Expedia verified reviews

EVEN Hotel Rochester - Mayo Clinic Area, an IHG Hotel

EVEN Hotel Rochester - Mayo Clinic Area, an IHG Hotel

5/5 Excellent
"Loved this property. The little touches are fantastic, including workout mats and balls inside the bedrooms and yoga in the morning. There was a good breakfast, all day coffee, etc. Large, quiet rooms that presumably include the space so that one can do exercise in the morning. It’s a quiet neighborhood next to the mayo clinic, but close to everything else. "
A verified traveler stayed at EVEN Hotel Rochester - Mayo Clinic Area, an IHG Hotel
Posted 15 hours ago
EVEN Hotel Rochester - Mayo Clinic Area, an IHG Hotel