Title: Southwest Illinois Vacation Rentals from $158: Search Short-Term Rentals | Expedia.com

[Southwest Illinois Travel Guide](https://expedia.com/Southwest-Illinois.dx6058943)[Hotels in Southwest Illinois](https://expedia.com/Southwest-Illinois-Hotels.d6058943.Travel-Guide-Hotels)[Flights to Southwest Illinois](https://expedia.com/Cheap-Flights-To-Southwest-Illinois.d6058943.Travel-Guide-Flights)[Car Rentals in Southwest Illinois](https://expedia.com/Car-Rentals-In-Southwest-Illinois.d6058943.Car-Rental-Guide)[Southwest Illinois Vacation Packages](https://expedia.com/Southwest-Illinois.d6058943.Destination-Travel-Guides)

![One of the northermost cypress swamps in the States, the Cache River State Natural area is home to Cypress trees that are over 1000 years old. This is shot from the hiking trail (no boat), and was just a sampling of the scores of cypress trees all around. #treetrove](https://images.trvl-media.com/place/553248634983556233/b4c981e9-72cf-4dc0-8b97-270e21fe73c6.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

Photo by Carl Anderson

![](https://images.trvl-media.com/place/553248634983556233/b4c981e9-72cf-4dc0-8b97-270e21fe73c6.jpg?impolicy=fcrop&w=1200&h=500&q=medium)

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## Check prices for these dates

In two weeks

[Mar 20 - Mar 22](https://www.expedia.com/Hotel-Search?regionId=6058943&startDate=2026-03-20&endDate=2026-03-22&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In two months

[May 1 - May 3](https://www.expedia.com/Hotel-Search?regionId=6058943&startDate=2026-05-01&endDate=2026-05-03&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In three months

[May 29 - May 31](https://www.expedia.com/Hotel-Search?regionId=6058943&startDate=2026-05-29&endDate=2026-05-31&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

In four months

[Jun 26 - Jun 28](https://www.expedia.com/Hotel-Search?regionId=6058943&startDate=2026-06-26&endDate=2026-06-28&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&rfrr=TG.LP.CheckPrices.Hotel&openPlayBack=true)

## Our top choices for Southwest Illinois vacation rentals

![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119740000/119734200/119734107/c7904d3a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119740000/119734200/119734107/98ac6197.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119740000/119734200/119734107/28c20fa0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119740000/119734200/119734107/870bf7d2.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### 12 Mi to St Louis: Pet-friendly Metro East Home

[](https://www.expedia.com/St-Louis-Hotels-12-Mi-To-St-Louis-Pet-Friendly-Metro-East-Home.h119734107.Hotel-Information)

Granite City

$186 nightly

$205 total

Mar 9 - Mar 10

Total with taxes and fees

[](https://www.expedia.com/St-Louis-Hotels-12-Mi-To-St-Louis-Pet-Friendly-Metro-East-Home.h119734107.Hotel-Information)

![House (2 Bedrooms) | Front of property](https://images.trvl-media.com/lodging/120000000/119740000/119734200/119734109/57d00814.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119740000/119734200/119734109/b80c1dc0.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119740000/119734200/119734109/6d3a02cd.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/120000000/119740000/119734200/119734109/b236e0dc.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Lakefront Family Home 13 Mi From Gateway Arch!

[](https://www.expedia.com/Lakefront-Family-Home-13-Mi-From-Gateway-Arch.h119734109.Hotel-Information)

Granite City

$364 nightly

$401 total

Mar 9 - Mar 10

Total with taxes and fees

[](https://www.expedia.com/Lakefront-Family-Home-13-Mi-From-Gateway-Arch.h119734109.Hotel-Information)

![House (1 Bedroom) | Front of property](https://images.trvl-media.com/lodging/124000000/123670000/123661900/123661842/aa6e717a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/124000000/123670000/123661900/123661842/d5f4e688.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/124000000/123670000/123661900/123661842/3ac16db9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (1 Bedroom) | Interior](https://images.trvl-media.com/lodging/124000000/123670000/123661900/123661842/3ed90f05.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Pet Friendly! Countryside Couples Stay in Illinois

[](https://www.expedia.com/Murphysboro-Hotels-Lakefront.h123661842.Hotel-Information)

Murphysboro

$217 nightly

$238 total

Mar 9 - Mar 10

Total with taxes and fees

[](https://www.expedia.com/Murphysboro-Hotels-Lakefront.h123661842.Hotel-Information)

![View from property](https://images.trvl-media.com/lodging/111000000/110560000/110550900/110550817/d4a93b47.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, desk, laptop workspace, bed sheets](https://images.trvl-media.com/lodging/111000000/110560000/110550900/110550817/72fc0b4a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, desk, laptop workspace, bed sheets](https://images.trvl-media.com/lodging/111000000/110560000/110550900/110550817/61c8f623.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![1 bedroom, desk, laptop workspace, bed sheets](https://images.trvl-media.com/lodging/111000000/110560000/110550900/110550817/b6c1f98e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy

[](https://www.expedia.com/French-Village-Hotels-Postcard-Cabins-St-Francois.h110550817.Hotel-Information)

French Village

9.8/10

Exceptional

(56 reviews)

"I had a great time with my mom there!"

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Lily

$134 nightly

$144 total

Mar 16 - Mar 17

Total with taxes and fees

[](https://www.expedia.com/French-Village-Hotels-Postcard-Cabins-St-Francois.h110550817.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/127000000/126620000/126617400/126617355/804f0425.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Iron/ironing board, free WiFi](https://images.trvl-media.com/lodging/127000000/126620000/126617400/126617355/9e44784b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Suite, 1 Queen Bed with Sofa bed, Pets Allowed | Interior](https://images.trvl-media.com/lodging/127000000/126620000/126617400/126617355/d395df9b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Exterior detail](https://images.trvl-media.com/lodging/127000000/126620000/126617400/126617355/2cb1c224.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### The Atrium - A Boutique Hotel

[](https://www.expedia.com/Perryville-Hotels-The-Atrium-A-Boutique-Hotel.h126617355.Hotel-Information)

Perryville

$127 nightly

$147 total

Mar 15 - Mar 16

Total with taxes and fees

[](https://www.expedia.com/Perryville-Hotels-The-Atrium-A-Boutique-Hotel.h126617355.Hotel-Information)

![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/123000000/122900000/122892200/122892138/9b8cfc2e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/123000000/122900000/122892200/122892138/2ea775b9.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (2 Bedrooms) | Front of property](https://images.trvl-media.com/lodging/123000000/122900000/122892200/122892138/fe5a3b48.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House (2 Bedrooms) | Interior](https://images.trvl-media.com/lodging/123000000/122900000/122892200/122892138/a51b6a8b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Quiet Country Stay: Modern Home Near Paducah

[](https://www.expedia.com/Quiet-Country-Stay-Modern-Home-Near-Paducah.h122892138.Hotel-Information)

Cunningham

$271 nightly

$290 total

Mar 9 - Mar 10

Total with taxes and fees

[](https://www.expedia.com/Quiet-Country-Stay-Modern-Home-Near-Paducah.h122892138.Hotel-Information)

![Full-size fridge, microwave, oven, stovetop](https://images.trvl-media.com/lodging/77000000/76390000/76388000/76388000/84406cc3.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Point of interest](https://images.trvl-media.com/lodging/77000000/76390000/76388000/76388000/2ec33dcf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Egyptian cotton sheets, premium bedding, down comforters](https://images.trvl-media.com/lodging/77000000/76390000/76388000/76388000/0b4f194a.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![55-inch Smart TV with digital channels, TV, streaming services](https://images.trvl-media.com/lodging/77000000/76390000/76388000/76388000/8010cd32.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Urban Lofts

[](https://www.expedia.com/Perryville-Hotels-Urban-Lofts.h76388000.Hotel-Information)

Perryville

9.2/10

Wonderful

(17 reviews)

"Great place to stay! "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Eric

$236 nightly

$270 total

Mar 9 - Mar 10

Total with taxes and fees

[](https://www.expedia.com/Perryville-Hotels-Urban-Lofts.h76388000.Hotel-Information)

![Terrace/patio](https://images.trvl-media.com/lodging/84000000/83520000/83516600/83516509/8557dc4b.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House | Living area](https://images.trvl-media.com/lodging/84000000/83520000/83516600/83516509/cbaecd07.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House | Living area](https://images.trvl-media.com/lodging/84000000/83520000/83516600/83516509/14339969.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House | 1 bedroom](https://images.trvl-media.com/lodging/84000000/83520000/83516600/83516509/e3c698b1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Tiny Houses of French Village

[](https://www.expedia.com/French-Village-Hotels-Tiny-Houses-Of-French-Village.h83516509.Hotel-Information)

French Village

10/10

Exceptional

(3 reviews)

"Charming property with a space for everything and everything in its place. Would not hesitate to recommend or stay again."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Norma

$325 nightly

$346 total

Mar 11 - Mar 12

Total with taxes and fees

[](https://www.expedia.com/French-Village-Hotels-Tiny-Houses-Of-French-Village.h83516509.Hotel-Information)

![Lobby](https://images.trvl-media.com/lodging/84000000/83130000/83121100/83121050/f3c125ad.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Lobby lounge](https://images.trvl-media.com/lodging/84000000/83130000/83121100/83121050/0920a26c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Comfort Apartment | Living area | 42-inch Smart TV with digital channels, TV, Netflix](https://images.trvl-media.com/lodging/84000000/83130000/83121100/83121050/4a627d76.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![BBQ/picnic area](https://images.trvl-media.com/lodging/84000000/83130000/83121100/83121050/0bbeb61f.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

###  White House at Grand Central

[](https://www.expedia.com/St-Louis-Hotels-Grand-Center-Apartments.h83121050.Hotel-Information)

Grand Center

8.4/10

Very Good

(128 reviews)

"Very clean and very friendly people "

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Mary

$121 nightly

$135 total

Mar 9 - Mar 10

Total with taxes and fees

[](https://www.expedia.com/St-Louis-Hotels-Grand-Center-Apartments.h83121050.Hotel-Information)

![Interior](https://images.trvl-media.com/lodging/127000000/126480000/126472100/126472041/78552352.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/127000000/126480000/126472100/126472041/823bb914.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/127000000/126480000/126472100/126472041/281b2e56.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Interior](https://images.trvl-media.com/lodging/127000000/126480000/126472100/126472041/c717ca95.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### 3323: Uptown Elegant Escape by JZ Vacation Rentals

[](https://www.expedia.com/St-Louis-Hotels-3323-Uptown-Elegant-Escape-By-JZ-Vacation-Rentals.h126472041.Hotel-Information)

The Gate

$721 nightly

$843 total

Mar 15 - Mar 16

Total with taxes and fees

[](https://www.expedia.com/St-Louis-Hotels-3323-Uptown-Elegant-Escape-By-JZ-Vacation-Rentals.h126472041.Hotel-Information)

![House, Multiple Beds, Patio, City View ((#19) 3323 Vista Ave) | Private kitchen](https://images.trvl-media.com/lodging/105000000/104010000/104008500/104008447/209d3104.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House, Multiple Beds, Patio, City View ((#19) 3323 Vista Ave) | 5 bedrooms, individually decorated, individually furnished, bed sheets](https://images.trvl-media.com/lodging/105000000/104010000/104008500/104008447/aa1a146c.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House, Multiple Beds, Patio, City View ((#19) 3323 Vista Ave) | Living area](https://images.trvl-media.com/lodging/105000000/104010000/104008500/104008447/80ab1b36.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![House, Multiple Beds, Patio, City View ((#19) 3323 Vista Ave) | Living area](https://images.trvl-media.com/lodging/105000000/104010000/104008500/104008447/f9583e7e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Uptown Elegant Escape | JZ Vacation Rentals

[](https://www.expedia.com/St-Louis-Hotels-Spacious-Family-Retreat-1-OF-2-JZ-Vacation-Rentals.h104008447.Hotel-Information)

The Gate

$708 nightly

$828 total

Mar 15 - Mar 16

Total with taxes and fees

[](https://www.expedia.com/St-Louis-Hotels-Spacious-Family-Retreat-1-OF-2-JZ-Vacation-Rentals.h104008447.Hotel-Information)

![Studio Suite, 1 King Bed | Desk, laptop workspace, blackout drapes, WiFi](https://images.trvl-media.com/lodging/1000000/20000/20000/19976/7caaaee1.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Combined shower/tub, towels, soap, shampoo](https://images.trvl-media.com/lodging/1000000/20000/20000/19976/af9b69ed.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Combined shower/tub, towels, soap, shampoo](https://images.trvl-media.com/lodging/1000000/20000/20000/19976/w2885h1876x11y0-1194952e.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

![Full-size fridge, microwave, stovetop, dishwasher](https://images.trvl-media.com/lodging/1000000/20000/20000/19976/ca0bafbf.jpg?impolicy=fcrop&w=357&h=201&p=1&q=medium)

### Value Suites Extended Stay - St Louis

[](https://www.expedia.com/St-Louis-Hotels-Craigshire-Suites.h19976.Hotel-Information)

Maryland Heights

7.0/10

Good

(1,110 reviews)

"We’ve stayed here twice before and have always been pleased with everything. Very good hotel close to what we need."

![United States](https://a.travel-assets.com/egds/marks/flags/us.svg)

Timothy

$475 nightly

$551 total

Mar 13 - Mar 14

Total with taxes and fees

[](https://www.expedia.com/St-Louis-Hotels-Craigshire-Suites.h19976.Hotel-Information)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

[View all properties](https://expedia.com/Hotel-Search?startDate=2026-03-22&endDate=2026-03-23&regionId=6058943&adults=2&categorySearch=vacation_rentals_option&stay_options_group=vacation_rentals_option&openPlayBack=true)

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## Find vacation rentals that suit your style

Cabins

[](https://www.expedia.com/Hotel-Search?destination=Southwest+Illinois%2C+Illinois%2C+United+States+of+America&regionId=6058943&latLong=38.229039%2C-89.444206&adults=2&startDate=2026-06-06&d1=2026-06-06&endDate=2026-06-09&d2=2026-06-09&lodging=CABIN)

Villas

[](https://www.expedia.com/Hotel-Search?destination=Southwest+Illinois%2C+Illinois%2C+United+States+of+America&regionId=6058943&latLong=38.229039%2C-89.444206&adults=2&startDate=2026-06-06&d1=2026-06-06&endDate=2026-06-09&d2=2026-06-09&lodging=VILLA)

Aparthotels

[](https://www.expedia.com/Hotel-Search?destination=Southwest+Illinois%2C+Illinois%2C+United+States+of+America&regionId=6058943&latLong=38.229039%2C-89.444206&adults=2&startDate=2026-06-06&d1=2026-06-06&endDate=2026-06-09&d2=2026-06-09&lodging=APART_HOTEL)

Private vacation homes

[](https://www.expedia.com/Hotel-Search?destination=Southwest+Illinois%2C+Illinois%2C+United+States+of+America&regionId=6058943&latLong=38.229039%2C-89.444206&adults=2&startDate=2026-06-06&d1=2026-06-06&endDate=2026-06-09&d2=2026-06-09&lodging=VACATION_HOME)

Apartments

[](https://www.expedia.com/Hotel-Search?destination=Southwest+Illinois%2C+Illinois%2C+United+States+of+America&regionId=6058943&latLong=38.229039%2C-89.444206&adults=2&startDate=2026-06-06&d1=2026-06-06&endDate=2026-06-09&d2=2026-06-09&lodging=APARTMENT)

Cottages

[](https://www.expedia.com/Hotel-Search?destination=Southwest+Illinois%2C+Illinois%2C+United+States+of+America&regionId=6058943&latLong=38.229039%2C-89.444206&adults=2&startDate=2026-06-06&d1=2026-06-06&endDate=2026-06-09&d2=2026-06-09&lodging=COTTAGE)

Condos

[](https://www.expedia.com/Hotel-Search?destination=Southwest+Illinois%2C+Illinois%2C+United+States+of+America&regionId=6058943&latLong=38.229039%2C-89.444206&adults=2&startDate=2026-06-06&d1=2026-06-06&endDate=2026-06-09&d2=2026-06-09&lodging=CONDO)

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## Top Southwest Illinois Hotel Reviews

![Super 8 by Wyndham O'Fallon](https://images.trvl-media.com/lodging/1000000/20000/11100/11071/055d0e3b_y.jpg)

### Super 8 by Wyndham O'Fallon

2/10 Terrible

"We choose not to stay, it was quite run down. We found one of many hotels in the downtown Shiloh area."

[](https://expedia.com/Collinsville-Hotels-Super-8-By-Wyndham-OFallon.h11071.Hotel-Information)

![Drury Inn & Suites St. Louis Fairview Heights](https://images.trvl-media.com/lodging/1000000/50000/41900/41802/91646e6b_y.jpg)

### Drury Inn & Suites St. Louis Fairview Heights

8/10 Good

"Room was clean, bed was comfortable. Our hall on the 3rd floor was quiet. The pool area was overcrowded and extremely noisy - full of screaming kids both nights we were there. The hottub was full of soap (?) bubbles and grownups drinking beer and glass bottles of liquor. The staff were very friendly and helpful during the evening happy hour, and the snacks were plentiful. Breakfast was quite good, too. I'd stay again, but I'd wish for a little more oversight in the pool area for the benefit of all the guests."

[](https://expedia.com/Collinsville-Hotels-Drury-Inn-Suites-St-Louis-Fairview-Heights.h41802.Hotel-Information)

![Seasons Inn & Suites Highland](https://images.trvl-media.com/lodging/1000000/210000/202600/202597/2bb7b058_y.jpg)

### Seasons Inn & Suites Highland

10/10 Excellent

"Good "

[](https://expedia.com/Highland-Hotels-Seasons-Inn-Suites-Highland.h202597.Hotel-Information)

![Drury Plaza Hotel Mt. Vernon](https://images.trvl-media.com/lodging/1000000/50000/42100/42021/798d901b_y.jpg)

### Drury Plaza Hotel Mt. Vernon

10/10 Excellent

"Was very nice to have complimentary cocktails and hors d'oeuvres, which was more like a meal. Also had hot breakfast with real eggs, not powdered. Very clean and our dog was welcomed. Very friendly workers. "

[](https://expedia.com/Mount-Vernon-Hotels-Drury-Inn-Suites-Mt-Vernon.h42021.Hotel-Information)

![Drury Inn & Suites Marion](https://images.trvl-media.com/lodging/1000000/50000/42100/42025/0b9bb173_y.jpg)

### Drury Inn & Suites Marion

6/10 Okay

"adequate"

[](https://expedia.com/Carbondale-Hotels-Drury-Inn-Marion.h42025.Hotel-Information)

![Drury Inn & Suites St. Louis O'Fallon, IL](https://images.trvl-media.com/lodging/2000000/1550000/1544100/1544028/2e5b0061_y.jpg)

### Drury Inn & Suites St. Louis O'Fallon, IL

10/10 Excellent

"Clean room"

[](https://expedia.com/Collinsville-Hotels-Drury-Inn-Suites-St-Louis-OFallon.h1544028.Hotel-Information)

![Quality Inn O'Fallon IL - St. Louis](https://images.trvl-media.com/lodging/1000000/70000/64700/64675/0a6ab208_y.jpg)

### Quality Inn O'Fallon IL - St. Louis

8/10 Good

"The room was fairly clean. The remote didn’t work. Probably needed batteries. The bathtub surround needs to be replaced. It was quiet and the beds were very comfortable."

[](https://expedia.com/Collinsville-Hotels-Quality-Inn-OFallon-I-64.h64675.Hotel-Information)

![Comfort Suites Mount Vernon](https://images.trvl-media.com/lodging/2000000/1390000/1387400/1387309/5b15716e_y.jpg)

### Comfort Suites Mount Vernon

6/10 Okay

"I was not impressed with the front staff on the day I checked in. She was trying to help me, but she was also talking on the phone. My opinion it didn't sound like a business call. :("

[](https://expedia.com/Mount-Vernon-Hotels-Comfort-Suites-Mount-Vernon.h1387309.Hotel-Information)

![Drury Inn & Suites St. Louis Collinsville](https://images.trvl-media.com/lodging/1000000/50000/42100/42035/fff178d6_y.jpg)

### Drury Inn & Suites St. Louis Collinsville

10/10 Excellent

"Great stay!"

[](https://expedia.com/Collinsville-Hotels-Drury-Inn-Suites-St-Louis-Collinsville.h42035.Hotel-Information)

## Find out more about Southwest Illinois

**Everything you need to know about Southwest Illinois vacation rentals**

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Southwest Illinois vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Southwest Illinois vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

**Southwest Illinois vacation rentals: An excellent choice for every season**

Whenever you want to travel, a warm welcome awaits you in Southwest Illinois. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Southwest Illinois in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $158 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

**How to find incredible deals on Southwest Illinois rentals**

At Expedia, we put the best Southwest Illinois vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Southwest Illinois rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Southwest Illinois vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Southwest Illinois. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

## Explore a world of travel with Expedia

- Trending destinations on Expedia.com
- All accommodation types in Southwest Illinois

### Trending destinations on Expedia.com

- [Destin Vacation Rentals ](https://www.expedia.com/Destin-Vacation-Rentals.d6906.Travel-Guide-VacationRentals)
- [Panama City Vacation Rentals ](https://www.expedia.com/Panama-City-Beach-Vacation-Rentals.d8021.Travel-Guide-VacationRentals)
- [Hilton Head Vacation Rentals ](https://www.expedia.com/Hilton-Head-Island-Vacation-Rentals.d601684.Travel-Guide-VacationRentals)
- [Gulf Shores Vacation Rentals ](https://www.expedia.com/Gulf-Shores-Vacation-Rentals.d603078.Travel-Guide-VacationRentals)
- [Key West Vacation Rentals ](https://www.expedia.com/Key-West-Vacation-Rentals.d1187.Travel-Guide-VacationRentals)
- [Gatlinburg Vacation Rentals ](https://www.expedia.com/Gatlinburg-Vacation-Rentals.d7474.Travel-Guide-VacationRentals)
- [Maui Vacation Rentals ](https://www.expedia.com/Maui-Vacation-Rentals.d180073.Travel-Guide-VacationRentals)
- [Orlando Vacation Rentals ](https://www.expedia.com/Orlando-Vacation-Rentals.d178294.Travel-Guide-VacationRentals)
- [Myrtle Beach Vacation Rentals ](https://www.expedia.com/Myrtle-Beach-Vacation-Rentals.d601685.Travel-Guide-VacationRentals)
- [Orange Beach Vacation Rentals ](https://www.expedia.com/Orange-Beach-Vacation-Rentals.d9136.Travel-Guide-VacationRentals)
- [Pigeon Forge Vacation Rentals ](https://www.expedia.com/Pigeon-Forge-Vacation-Rentals.d8264.Travel-Guide-VacationRentals)
- [Ocean City Vacation Rentals ](https://www.expedia.com/Ocean-City-Vacation-Rentals.d9151.Travel-Guide-VacationRentals)
- [Outer Banks Vacation Rentals ](https://www.expedia.com/Outer-Banks-Vacation-Rentals.d602135.Travel-Guide-VacationRentals)
- [San Diego Vacation Rentals ](https://www.expedia.com/San-Diego-Vacation-Rentals.d3073.Travel-Guide-VacationRentals)
- [Siesta Key Vacation Rentals ](https://www.expedia.com/Siesta-Key-Vacation-Rentals.d6881.Travel-Guide-VacationRentals)
- [Galveston Vacation Rentals ](https://www.expedia.com/Galveston-Vacation-Rentals.d1341.Travel-Guide-VacationRentals)
- [Clearwater Beach Vacation Rentals ](https://www.expedia.com/Clearwater-Beach-Vacation-Rentals.d10759.Travel-Guide-VacationRentals)
- [Palm Springs Vacation Rentals ](https://www.expedia.com/Palm-Springs-Vacation-Rentals.d180676.Travel-Guide-VacationRentals)
- [Florida Keys Vacation Rentals ](https://www.expedia.com/Florida-Keys-Vacation-Rentals.d6023765.Travel-Guide-VacationRentals)
- [Lake Tahoe Vacation Rentals ](https://www.expedia.com/South-Lake-Tahoe-Vacation-Rentals.d10150.Travel-Guide-VacationRentals)
- [Lake of the Ozarks Vacation Rentals ](https://www.expedia.com/Lake-Ozark-Vacation-Rentals.d177772.Travel-Guide-VacationRentals)
- [Florida Vacation Rentals ](https://www.expedia.com/Destinations-In-Florida.d211.Vacation-Rental-Destinations)
- [Hawaii Vacation Rentals ](https://www.expedia.com/Destinations-In-Hawaii.d213.Vacation-Rental-Destinations)
- [Michigan Vacation Rentals ](https://www.expedia.com/Destinations-In-Michigan.d224.Vacation-Rental-Destinations)

- [Vacation Homes in Southwest Illinois ](https://expedia.com/Southwest-Illinois-Private-Vacation-Homes.d6058943-aaPrivateVacationHomes.Travel-Guide-Accommodation)
- [Cabin Rentals in Southwest Illinois ](https://expedia.com/Southwest-Illinois-Cabins.d6058943-aaCabins.Travel-Guide-Accommodation)
- [Apartments in Southwest Illinois ](https://expedia.com/Southwest-Illinois-Apartments.d6058943-aaApartments.Travel-Guide-Accommodation)
- [Motels in Southwest Illinois ](https://expedia.com/Southwest-Illinois-Motels.d6058943-aaMotels.Travel-Guide-Accommodation)
- [RV Parks in Southwest Illinois ](https://expedia.com/Southwest-Illinois-RV-Parks.d6058943-aaRVParks.Travel-Guide-Accommodation)
- [Cottages in Southwest Illinois ](https://expedia.com/Southwest-Illinois-Cottages.d6058943-aaCottages.Travel-Guide-Accommodation)
- [Farmstay in Southwest Illinois ](https://expedia.com/Southwest-Illinois-Agritourism.d6058943-aaAgritourism.Travel-Guide-Accommodation)
- [B&B in Southwest Illinois ](https://expedia.com/Southwest-Illinois-Bed-And-Breakfast.d6058943-aaBedAndBreakfast.Travel-Guide-Accommodation)
- [Condo Rentals in Southwest Illinois ](https://expedia.com/Southwest-Illinois-Condos.d6058943-aaCondos.Travel-Guide-Accommodation)
- [Lodges in Southwest Illinois ](https://expedia.com/Southwest-Illinois-Lodges.d6058943-aaLodges.Travel-Guide-Accommodation)
- [Guest Houses in Southwest Illinois ](https://expedia.com/Southwest-Illinois-Guest-Houses.d6058943-aaGuestHouses.Travel-Guide-Accommodation)
- [Villas in Southwest Illinois ](https://expedia.com/Southwest-Illinois-Villas.d6058943-aaVillas.Travel-Guide-Accommodation)
- [Resorts in Southwest Illinois ](https://expedia.com/Southwest-Illinois-Resorts.d6058943-aaResorts.Travel-Guide-Accommodation)

### Expedia's Latest Trends

Hotels

- [Central Illinois Luxury Hotels](https://expedia.com/Central-Illinois-Hotels-Luxury-Hotel.0-0-d6059219-tLuxuryHotel.Travel-Guide-Filter-Hotels)
- [Northern Illinois Family Hotels](https://expedia.com/Northern-Illinois-Hotels-Family-Hotel.0-0-d6058965-tFamilyHotel.Travel-Guide-Filter-Hotels)
- [Southern Illinois Fishing Resorts & Hotels](https://expedia.com/Southern-Illinois-Hotels-Fishing-Hotels.0-0-d6233859-tFishingHotels.Travel-Guide-Filter-Hotels)
- [Hotels in Northwest Chicago](https://expedia.com/Northwest-Chicago-Hotels.d6350697.Travel-Guide-Hotels)
- [Western Suburbs Luxury Hotels](https://expedia.com/Western-Suburbs-Hotels-Luxury-Hotel.0-0-d6059325-tLuxuryHotel.Travel-Guide-Filter-Hotels)
- [Northwest Chicago Luxury Hotels](https://expedia.com/Northwest-Chicago-Hotels-Luxury-Hotel.0-0-d6350697-tLuxuryHotel.Travel-Guide-Filter-Hotels)
- [Northern Illinois Casinos](https://expedia.com/Northern-Illinois-Hotels-Casino-Hotel.0-0-d6058965-tCasinoHotel.Travel-Guide-Filter-Hotels)
- [Central Illinois Adults Only Resorts & Hotels](https://expedia.com/Central-Illinois-Hotels-Adults-Only-Resorts.0-0-d6059219-tAdultsOnlyResorts.Travel-Guide-Filter-Hotels)
- [Hotels in Western Suburbs](https://expedia.com/Western-Suburbs-Hotels.d6059325.Travel-Guide-Hotels)
- [Hotels in Southern Illinois](https://expedia.com/Southern-Illinois-Hotels.d6233859.Travel-Guide-Hotels)
- [South Suburbs Luxury Hotels](https://expedia.com/South-Suburbs-Hotels-Luxury-Hotel.0-0-d6264251-tLuxuryHotel.Travel-Guide-Filter-Hotels)
- [Southern Illinois Luxury Hotels](https://expedia.com/Southern-Illinois-Hotels-Luxury-Hotel.0-0-d6233859-tLuxuryHotel.Travel-Guide-Filter-Hotels)
- [Southern Illinois Resorts & Hotels with Spas](https://expedia.com/Southern-Illinois-Hotels-Spa-Hotel.0-0-d6233859-tSpaHotel.Travel-Guide-Filter-Hotels)
- [Western Suburbs Hotels with an Indoor Pool](https://expedia.com/Western-Suburbs-Hotels-Hotels-With-Indoor-Pool.0-0-d6059325-tHotelswithIndoorPool.Travel-Guide-Filter-Hotels)
- [Southern Illinois Romantic Hotels](https://expedia.com/Southern-Illinois-Hotels-Romantic-Hotel.0-0-d6233859-tRomanticHotel.Travel-Guide-Filter-Hotels)
- [Drury Inn & Suites Hotels in Central Illinois](https://expedia.com/Central-Illinois-Hotels-Drury-Inn-Suites.0-0-d6059219--bDruryInnSuites.Travel-Guide-Filter-Hotels)
- [Hotels in South Suburbs](https://expedia.com/South-Suburbs-Hotels.d6264251.Travel-Guide-Hotels)
- [Southern Illinois Casinos](https://expedia.com/Southern-Illinois-Hotels-Casino-Hotel.0-0-d6233859-tCasinoHotel.Travel-Guide-Filter-Hotels)

Flights

- [Southern Illinois Flights](https://expedia.com/lp/flights/6233859/flights-from-southern-illinois)
- [Flights to Southern Illinois](https://expedia.com/Cheap-Flights-To-Southern-Illinois.d6233859.Travel-Guide-Flights)

Activities

- [Things to do in Western Illinois](https://expedia.com/Things-To-Do-In-Western-Illinois.d6058920.Travel-Guide-Activities)
- [Things to do in Northwest Chicago](https://expedia.com/Things-To-Do-In-Northwest-Chicago.d6350697.Travel-Guide-Activities)
- [Things to do in Central Illinois](https://expedia.com/Things-To-Do-In-Central-Illinois.d6059219.Travel-Guide-Activities)
- [Things to do in Northern Illinois](https://expedia.com/Things-To-Do-In-Northern-Illinois.d6058965.Travel-Guide-Activities)

General

- [Visit Southern Illinois](https://expedia.com/Southern-Illinois.dx6233859)
- [Visit Western Illinois](https://expedia.com/Western-Illinois.dx6058920)
- [Visit Southeast Illinois](https://expedia.com/Southeast-Illinois.dx6058934)
- [Visit Northern Illinois](https://expedia.com/Northern-Illinois.dx6058965)
- [Visit Western Suburbs](https://expedia.com/Western-Suburbs.dx6059325)
- [Visit Central Illinois](https://expedia.com/Central-Illinois.dx6059219)

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