An aerial view of a town with industrial buildings, roads, and green areas.

St. Charles Vacation Rentals

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Check prices for these dates

In two weeks
Oct 30 - Nov 1
In two months
Dec 11 - Dec 13
In three months
Jan 8 - Jan 10
In four months
Feb 5 - Feb 7

Our top choices for St. Charles vacation rentals

A wooden cabin with a porch, two chairs, and a door.

1. Tiny Treehouse Cabin | Bluff Woodlands #2

Tiny Treehouse Cabin | Bluff Woodlands #2
Elba
9.8 out of 10, Exceptional, (17 reviews)
"Beautiful area enjoyed our stay immensely"
United Kingdom
I.M l.
$179 nightly
The price is $192
Oct 20 - Oct 21
Total with taxes and fees
Tiny Treehouse Cabin | Bluff Woodlands #2
A covered deck with outdoor seating, surrounded by a forested area.

2. Tiny Treehouse Cabin | Bluff Woodlands #3

Tiny Treehouse Cabin | Bluff Woodlands #3
Elba
10.0 out of 10, Exceptional, (13 reviews)
"My family of 4 had a wonderful stay!"
United States
Josh S.
$191 nightly
The price is $205
Oct 18 - Oct 19
Total with taxes and fees
Tiny Treehouse Cabin | Bluff Woodlands #3
Two wooden cabins elevated on stilts in a forest, with outdoor seating and hammocks.

3. Tiny Treehouse Cabin | Bluff Woodlands #1

Tiny Treehouse Cabin | Bluff Woodlands #1
Elba
9.6 out of 10, Exceptional, (10 reviews)
"Great area a place to stay. "
United States
Paul T.
$191 nightly
The price is $205
Oct 18 - Oct 19
Total with taxes and fees
Tiny Treehouse Cabin | Bluff Woodlands #1
A living room with a television, sofa, coffee table, and shelves with decorative items.

4. Vintage Lustron Home Piece of History

Vintage Lustron Home Piece of History
Minnesota City
10.0 out of 10, Exceptional, (36 reviews)
"A beautiful comfortable welcoming home!"
United States
Jocelyn R.
$199 nightly
The price is $214
Oct 20 - Oct 21
Total with taxes and fees
Vintage Lustron Home Piece of History
A small brick building with a sign reading 'WYKOFF JAIL HOUSE.'

5. Wykoff Historical Jail Haus with Original Jail Cell Bunks.

Wykoff Historical Jail Haus with Original Jail Cell Bunks.
Wykoff
10.0 out of 10, Exceptional, (6 reviews)
"Phenomenal communication with Becky, our host. Will be coming to this property again. It is unique and unlike anything I ever stayed at before. It was a jail in its former life after all. Very authentic with a modern twist. Great place!!!"
United States
Peggy
$125 nightly
The price is $134
Oct 18 - Oct 19
Total with taxes and fees
Wykoff Historical Jail Haus with Original Jail Cell Bunks.
A living room with a blue sofa, yellow cushions, a patterned rug, and a coffee table with a vintage design.

6. The Little House | 1 mi from downtown, Love Pets!

The Little House | 1 mi from downtown, Love Pets!
Slatterly Park
10.0 out of 10, Exceptional, (22 reviews)
"Beautiful little house and comfortable stay."
United States
Cheryl P.
$228 nightly
The price is $262
Oct 18 - Oct 19
Total with taxes and fees
The Little House | 1 mi from downtown, Love Pets!
A two-story house with a covered patio and a pathway leading to the entrance.

7. Magical Nest Hideaway

Magical Nest Hideaway
Rochester
10.0 out of 10, Exceptional, (169 reviews)
"Greg is a wonderful host, and the place is both beautiful and peaceful!"
United States
Paul H.
$163 nightly
The price is $188
Oct 15 - Oct 16
Total with taxes and fees
Magical Nest Hideaway
A kitchen with white cabinets, a sink, and a coffee maker.

8. Discounted Oasis, 2 Bedroom Lower-Level Duplex 5 Minutes to Mayo Clinic!

Discounted Oasis, 2 Bedroom Lower-Level Duplex 5 Minutes to Mayo Clinic!
Rochester
9.4 out of 10, Exceptional, (34 reviews)
"Close to Mayo's and shopping."
United States
Cathy
$208 nightly
The price is $239
Oct 24 - Oct 25
Total with taxes and fees
Discounted Oasis, 2 Bedroom Lower-Level Duplex 5 Minutes to Mayo Clinic!
A rustic wooden pavilion with picnic tables, surrounded by a gravel area and grassy lawn.

9. Cozy River Cabin w/ Loft & Screened Porch

Cozy River Cabin w/ Loft & Screened Porch
Buffalo City
10.0 out of 10, Exceptional, (2 reviews)
"It was a in and out stay. Would have liked to been able to check in earlier since we came from a distance and woulda been nice to have a place to change church clothes without a fee. Other than that all worked out."
United States
John S.
$156 nightly
The price is $164
Oct 18 - Oct 19
Total with taxes and fees
Cozy River Cabin w/ Loft & Screened Porch
Exterior

10. Riverfront Cabin with Private Dock

Riverfront Cabin with Private Dock
Buffalo City
10.0 out of 10, Exceptional, (5 reviews)
"Great place!!!"
United States
Cynthia B.
$150 nightly
The price is $158
Oct 20 - Oct 21
Total with taxes and fees
Riverfront Cabin with Private Dock
A hotel room with a large bed, two bedside tables, a wooden door, and a wall-mounted artwork.

11. UrbanCottage | 1mi Mayo Clinic, No Stairs, Dogs OK

UrbanCottage | 1mi Mayo Clinic, No Stairs, Dogs OK
East Side Pioneers
$182 nightly
The price is $209
Nov 8 - Nov 9
Total with taxes and fees
UrbanCottage | 1mi Mayo Clinic, No Stairs, Dogs OK
A modern living room with a brown leather sofa, a white armchair, a coffee table, and a dining area with a table and chairs.

12. The June | Private 1br Basement Apt, Pets Welcome!

The June | Private 1br Basement Apt, Pets Welcome!
Rochester
10.0 out of 10, Exceptional, (7 reviews)
"This place was quiet, comfortable, well-stocked, and incredibly close to everything we were looking for. The hosts were great communicators, and accessing the place was a snap."
United States
Josh P.
$226 nightly
The price is $260
Oct 15 - Oct 16
Total with taxes and fees
The June | Private 1br Basement Apt, Pets Welcome!
A bedroom with a large bed, a TV on a dresser, and a view of the city through large windows.

13. Broadway Plaza, Trademark Collection by Wyndham

Broadway Plaza, Trademark Collection by Wyndham
3.0 star property
Downtown Rochester
9.2 out of 10, Wonderful, (183 reviews)
"The staff were friendly and very helpful when we had questions. The kitchen was well equipped and clean. The parking was handy and lived the Skywalks."
United States
Danny
$169 nightly
The price is $195
Oct 24 - Oct 25
Total with taxes and fees
Broadway Plaza, Trademark Collection by Wyndham
A living room with a television displaying a scenic view, a dark armchair, a sofa, and a wooden coffee table.

14. 2 steps entry 1mile to Mayo CoveredByFaith Inspire

2 steps entry 1mile to Mayo CoveredByFaith Inspire
Parkway
10.0 out of 10, Exceptional, (3 reviews)
"Great pet friendly option"
United States
Erik G.
$255 nightly
The price is $293
Oct 18 - Oct 19
Total with taxes and fees
2 steps entry 1mile to Mayo CoveredByFaith Inspire
A wooden cabin with a porch, two chairs, and a door.

15. Three Treehouse Cabins in the Bluff Woodlands

Three Treehouse Cabins in the Bluff Woodlands
Elba
$526 nightly
The price is $566
Oct 20 - Oct 21
Total with taxes and fees
Three Treehouse Cabins in the Bluff Woodlands
A living room with a dark brown sofa, two trash bins, a framed artwork of an artichoke, and a lamp on a side table.

16. Across from St Marys hospital Covered By Faith 2

Across from St Marys hospital Covered By Faith 2
Kutzky Park
8.0 out of 10, Very good, (2 reviews)
"Easy check in/ Secure entry system "
United States
Ann R.
$158 nightly
The price is $182
Oct 21 - Oct 22
Total with taxes and fees
Across from St Marys hospital Covered By Faith 2
A laundry area with a washer, dryer, and various cleaning supplies on shelves.

17. ColorHouse | 1 mi to Mayo Clinic, No Stairs Entry

ColorHouse | 1 mi to Mayo Clinic, No Stairs Entry
East Side Pioneers
9.0 out of 10, Wonderful, (14 reviews)
$280 nightly
The price is $322
Oct 15 - Oct 16
Total with taxes and fees
ColorHouse | 1 mi to Mayo Clinic, No Stairs Entry
A wooden cabin interior with a dining table, chairs, a refrigerator, a stove, and a ladder leading to a loft.

18. Badger Cabin w/ Lofts, Fireplace & WiFi

Badger Cabin w/ Lofts, Fireplace & WiFi
Buffalo City
10.0 out of 10, Exceptional, (1 review)
$174 nightly
The price is $184
Oct 20 - Oct 21
Total with taxes and fees
Badger Cabin w/ Lofts, Fireplace & WiFi
A park with a river, green grass, and trees. There is a building in the background.

19. 7blks Mayo Gonda 8blks St Marys 3 Bed Main Floor

7blks Mayo Gonda 8blks St Marys 3 Bed Main Floor
Kutzky Park
9.4 out of 10, Exceptional, (17 reviews)
"Very easy experience. Lovely home"
United States
Laurie T.
$271 nightly
The price is $312
Oct 15 - Oct 16
Total with taxes and fees
7blks Mayo Gonda 8blks St Marys 3 Bed Main Floor
A two-story house with a wooden staircase leading to a yellow door, a brick wall, and a window with a white frame.

20. Charming 1BR house with WiFi, AC, Private Patio + Cruiser Bikes & Grill Add-Ons

Charming 1BR house with WiFi, AC, Private Patio + Cruiser Bikes & Grill Add-Ons
Historic Downtown Winona
10.0 out of 10, Exceptional, (34 reviews)
"Very clean, great hosts, fully equipped we everything we needed. "
United States
Amy B.
$196 nightly
The price is $218
Oct 19 - Oct 20
Total with taxes and fees
Charming 1BR house with WiFi, AC, Private Patio + Cruiser Bikes & Grill Add-Ons
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top St. Charles Hotel Reviews

Find out more about St. Charles

Everything you need to know about St. Charles vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the St. Charles vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect St. Charles vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

St. Charles vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in St. Charles. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit St. Charles in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on St. Charles rentals

At Expedia, we put the best St. Charles vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top St. Charles rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream St. Charles vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around St. Charles. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

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Frequently asked questions

Can I find vacation rentals in St. Charles?

Yes, we offer vacation rentals close to the most popular attractions in St. Charles, or you can go with a more remote option if you want a relaxing place to stay. St. Charles is known for its parks.

What are some of the best vacation rentals that St. Charles has to offer?

Clean, fun, comfy ranch home near parks, 2.5 mi to Mayo w Pingpong and Playroom: Visitors like this St. Charles vacation home rental. It offers a patio, a garden, and a barbecue grill to help you feel perfectly comfortable in your new surroundings. It has 3 bedrooms as well as a kitchen with a dishwasher, a fridge, and a stovetop, so you can cook with friends or family. Make the most of the selection of games in this rental home to help you unwind.

What can I see and do in St. Charles?

While you're exploring the area, Whitewater River and Quarry Hill Nature Center are a couple of picturesque spots to get outside and enjoy nature. Whitewater State Park and St. Mary's University of Minnesota are a couple of places you'll find in the larger area.

What are vacation rentals like in St. Charles?

Vacation rentals are privately owned properties you can book for short or long periods in St. Charles. Vacation rentals feature amenities such as patios, hot tubs, and fire pits so your stay will be comfortable. If you're concerned about a clean environment, a vacation rental can offer a sense of seclusion away from public hotel elevators and lobbies bustling with people while still allowing you to travel. You'll also find more space in a vacation rental than in a traditional hotel, which is another reason why a vacation rental is an attractive choice for families.