Upstate South Carolina Vacation Rentals from $71: Search Short-Term Rentals

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Our top choices for Upstate South Carolina vacation rentals

1. stayAPT Suites Greenville-Haywood Mall

Greenville

Bentrez

$129 nightly

Nov 8 - Nov 9

Total with taxes and fees

A modern living room with a sofa, a coffee table, a TV, and a balcony with a view of buildings.

2. Mint House Greenville Downtown by Kasa

Greenville Downtown

Michelle

$140 nightly

Nov 19 - Nov 20

Total with taxes and fees

A house with a yellow door, a window, and a porch with a railing.

3. Cozy 1BR Close to Downtown & Greenville Drive Baseball

Greenville

isaiah

$140 nightly

Oct 22 - Oct 23

Total with taxes and fees

A modern building with outdoor seating and a garden.

4. The Station by Compo Hotels

Travelers Rest

Anonymous traveler

$313 nightly

Nov 17 - Nov 18

Total with taxes and fees

A spacious living area with a large window, a dining table, and a modern sofa.

5. Elegant 2BD Escape | Prime Location near DT GVL

Greenville

Candace C.

$245 nightly

Oct 28 - Oct 29

Total with taxes and fees

A hotel entrance with glass doors, a caution sign, a potted plant, and a red mat.

6. 2 Queen Beds Non-Smoking

Greenville SC

Anonymous traveler

$59 nightly

Nov 15 - Nov 16

Total with taxes and fees

A living room with a dark sofa, a coffee table, a lamp, and a flat-screen TV mounted on the wall.

7. Cozy Apt. Near Downtown (2BR, 1BA, 3 beds)

Greenville

Pat

$150 nightly

Oct 25 - Oct 26

Total with taxes and fees

A modern kitchen with white cabinets, stainless steel appliances, a granite countertop, and a built-in oven.

8. The Blue Bungalow by Unity Park - Newly Renovated

Woodside Cotton Mill Village Historic District

Ron E.

$211 nightly

Nov 17 - Nov 18

Total with taxes and fees

A hotel room with a bed, a sofa, a small table, a lamp, and a refrigerator.

9. 1 Queen Bed | Non-Smoking, Micfridge

Greenville SC

Anonymous traveler

$65 nightly

Oct 25 - Oct 26

Total with taxes and fees

A house with a gravel driveway, a wooden fence, and a lawn.

10. Secluded Tiny Home in Exclusive Paris Mountain!

Greenville

craig d.

$153 nightly

Oct 25 - Oct 26

Total with taxes and fees

A log cabin with a wooden door, two windows, and a chimney. There are two white metal chairs and a small table in front of the cabin.

11. Historic 19th Century Cabin in Greenville

Greenville

John A.

$142 nightly

Oct 25 - Oct 26

Total with taxes and fees

12. Skyline Split B Retreat Close to Everything You Need! Quiet, Clean & Convenient.

Woodside Cotton Mill Village Historic District

lisa E.

$243 nightly

Oct 26 - Oct 27

Total with taxes and fees

A modern kitchen with a stainless steel refrigerator, a microwave, and a sink. There is a wooden dining table with chairs and a laundry basket labeled "laundry" in the foreground.

13. 2BR 2Bath - Swamp Rabbit Trail Resort

Greenville

Randolph

$171 nightly

Oct 22 - Oct 23

Total with taxes and fees

A swimming pool with lounge chairs and a covered area with tables and chairs.

14. Carolina Camp Cedar

Pickens

Katlynn

$175 nightly

Oct 27 - Oct 28

Total with taxes and fees

A modern living room with a sofa, a coffee table, and a TV. There is a kitchen area with a microwave, stove, and refrigerator.

15. Adorable Upscale cottage in Downtown Fountain Inn.

Fountain Inn

Valerie

$248 nightly

Oct 22 - Oct 23

Total with taxes and fees

A modern kitchen with granite countertops, stainless steel appliances, and a dining area with a sofa and table.

16. 2BR Cedar Lane Road Retreat at Swamp Rabbit Trail!

Greenville

Gabriel D.

$171 nightly

Oct 25 - Oct 26

Total with taxes and fees

A cabin with a cozy interior, a wooden exterior, and a view of the forest.

17. Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Seneca

Winston

$133 nightly

Oct 26 - Oct 27

Total with taxes and fees

A hallway with wooden flooring, a blue patterned rug, and a modern pendant light fixture.

18. GORGEOUS 1 BR on MAIN #2

Greenville Downtown

HHI Surf Villa H.

$220 nightly

Oct 22 - Oct 23

Total with taxes and fees

A statue of a man holding a sword in front of a building with a sign reading "Fidelity Investments".

19. Riverwalk Falls-lovely one bedroom condo

Greenville Downtown

Brandy M.

$302 nightly

Nov 1 - Nov 2

Total with taxes and fees

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Top Upstate South Carolina Hotel Reviews

Best Western Plus Greenville I-385 Inn & Suites

10/10 Excellent

"Great stay"

Mint House Greenville Downtown by Kasa

8/10 Good

"Great location and in vicinity/walking to Reedy Falls, shops, food & ice cream, and Grand Bohemian Lodge, too! Walk the pathway along the river and seeing the boulder water falls was exceptionally special! Balcony was a nice view of city life. Parking for a fee was conveniently located for access to the property. Kitchen was large and equipped well for simple dinner. The Laundry room with detergent was useful, too!"

Clemson University's James F. Martin Inn

10/10 Excellent

"The room was on the ground level so walked out onto the gorgeous sprawling golf course and the lake and the beautiful pool/hot tub facilites. The location was great for where you meet to start a Clemson tour, however it's completely away from the main part of campus and the town otherwise, so nothing is really walkable from it. That's not a big deal b/c everything is a less than 5-10 min drive and the location is so pretty and peaceful it's worth it. we used the pool and hot tub at 8pm and were the only ones there and it was really lovely. The bed was incredibly hard, which was my only complaint."

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

8/10 Good

"Had some issues with the room but they were minor. The door was difficult to close and lock without having to lean against the door to lock it. The upper lock was loose (safety issue). The grab bar in shower also needed some tightening. For the price, I thought it would be better. I did enjoy my stay though. Just pointing out a few things that could easily be fixed checking between guests."

Find out more about Upstate South Carolina

Everything you need to know about Upstate South Carolina vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Upstate South Carolina vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Upstate South Carolina vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Upstate South Carolina vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Upstate South Carolina. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Upstate South Carolina in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $71 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Upstate South Carolina rentals

At Expedia, we put the best Upstate South Carolina vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Upstate South Carolina rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Upstate South Carolina vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Upstate South Carolina. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

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Check prices for these dates

Our top choices for Upstate South Carolina vacation rentals

1. stayAPT Suites Greenville-Haywood Mall

2. Mint House Greenville Downtown by Kasa

3. Cozy 1BR Close to Downtown & Greenville Drive Baseball

4. The Station by Compo Hotels

5. Elegant 2BD Escape | Prime Location near DT GVL

6. 2 Queen Beds Non-Smoking

7. Cozy Apt. Near Downtown (2BR, 1BA, 3 beds)

8. The Blue Bungalow by Unity Park - Newly Renovated

9. 1 Queen Bed | Non-Smoking, Micfridge

10. Secluded Tiny Home in Exclusive Paris Mountain!

11. Historic 19th Century Cabin in Greenville

12. Skyline Split B Retreat Close to Everything You Need! Quiet, Clean & Convenient.

13. 2BR 2Bath - Swamp Rabbit Trail Resort

14. Carolina Camp Cedar

15. Adorable Upscale cottage in Downtown Fountain Inn.

16. 2BR Cedar Lane Road Retreat at Swamp Rabbit Trail!

17. Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

18. GORGEOUS 1 BR on MAIN #2

19. Riverwalk Falls-lovely one bedroom condo

Find vacation rentals that suit your style

Top Upstate South Carolina Hotel Reviews

Best Western Plus Greenville I-385 Inn & Suites

Mint House Greenville Downtown by Kasa

Comfort Suites Greenville Airport

Hotel Hartness

Clemson University's James F. Martin Inn

Hyatt Place Greenville Downtown

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Find out more about Upstate South Carolina

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