A bench, a bicycle, and a lake surrounded by trees.

Upstate South Carolina Vacation Rentals

Check prices for these dates

In two weeks
Nov 27 - Nov 29
In two months
Jan 8 - Jan 10
In three months
Feb 5 - Feb 7
In four months
Mar 5 - Mar 7

Our top choices for Upstate South Carolina vacation rentals

Private kitchen

1. stayAPT Suites Greenville-Haywood Mall

stayAPT Suites Greenville-Haywood Mall
3.0 star property
Greenville
9.0 out of 10, Wonderful, (242 reviews)
"Great property and cozy. Safe area and close to mall and restaurants."
United States
Samantha Ann
$123 nightly
The price is $135
Nov 22 - Nov 23
Total with taxes and fees
stayAPT Suites Greenville-Haywood Mall
A modern living room with a sofa, a coffee table, a TV, and a balcony with a view of buildings.

2. Mint House Greenville Downtown by Kasa

Mint House Greenville Downtown by Kasa
4.0 star property
Greenville Downtown
9.2 out of 10, Wonderful, (949 reviews)
"Great location-we walked to soo many shops and restaurants!"
United States
Deborah
$99 nightly
The price is $109
Dec 1 - Dec 2
Total with taxes and fees
Mint House Greenville Downtown by Kasa
A modern building with outdoor seating and a garden.

3. The Station by Compo Hotels

The Station by Compo Hotels
4.0 star property
Travelers Rest
10.0 out of 10, Exceptional, (26 reviews)
"Lovely place to stay. Very clean and well appointed. The host was responsive and welcoming. Comfortable bed and quiet. Highly recommend."
United States
Anonymous traveler
$293 nightly
The price is $322
Nov 29 - Nov 30
Total with taxes and fees
The Station by Compo Hotels
A hotel room with a bed, desk, chair, and a bathroom with a mirror and sink.

4. King Bed Non-Smoking

King Bed Non-Smoking
Greenville SC
10.0 out of 10, Exceptional, (135 reviews)
"The location is fantastic if you're aiming to see local sights easily without stress,just a short drive or even a delightful walk if you have extra time!"
United States
Anonymous traveler
$66 nightly
The price is $71
Nov 14 - Nov 15
Total with taxes and fees
King Bed Non-Smoking
A hotel room with a bed, a sofa, a small table, a lamp, and a refrigerator.

5. 1 Queen Bed | Non-Smoking, Micfridge

1 Queen Bed | Non-Smoking, Micfridge
Greenville SC
9.4 out of 10, Exceptional, (52 reviews)
"I absolutely love it here"
United States
Anonymous traveler
$51 nightly
The price is $56
Nov 23 - Nov 24
Total with taxes and fees
1 Queen Bed | Non-Smoking, Micfridge
A modern apartment with a living room, kitchen, and dining area. There is a sofa, a coffee table, and a TV.

6. 1 bedroom apt, Steps from Swamp Rabbit Trail, 15 minute walk to Main st.

1 bedroom apt, Steps from Swamp Rabbit Trail, 15 minute walk to Main st.
Greenville Downtown
10.0 out of 10, Exceptional, (15 reviews)
"Great location in downtown Greenville!"
United States
C. David S.
$235 nightly
The price is $259
Nov 24 - Nov 25
Total with taxes and fees
1 bedroom apt, Steps from Swamp Rabbit Trail, 15 minute walk to Main st.
A modern kitchen with white cabinets, stainless steel appliances, a granite countertop, and a built-in oven.

7. The Blue Bungalow by Unity Park - Newly Renovated

The Blue Bungalow by Unity Park - Newly Renovated
Woodside Cotton Mill Village Historic District
9.8 out of 10, Exceptional, (115 reviews)
"Fully equipped, comfortable beds…everything to make for an enjoyable stay. "
United States
Ron E.
$194 nightly
The price is $213
Nov 17 - Nov 18
Total with taxes and fees
The Blue Bungalow by Unity Park - Newly Renovated
A living room with a sofa, coffee table, and a ceiling fan.

8. Cozy 1BR Close to Downtown & Greenville Drive Baseball

Cozy 1BR Close to Downtown & Greenville Drive Baseball
Greenville
9.0 out of 10, Wonderful, (34 reviews)
"Good location, great communication"
United States
isaiah
$164 nightly
The price is $180
Nov 22 - Nov 23
Total with taxes and fees
Cozy 1BR Close to Downtown & Greenville Drive Baseball
A spacious living area with a large window, a dining table, and a modern sofa.

9. Elegant 2BD Escape | Prime Location near DT GVL

Elegant 2BD Escape | Prime Location near DT GVL
Greenville
9.4 out of 10, Exceptional, (9 reviews)
"Very clean and nice property. Pet friendly and on a great large converted mill building with a pool and outdoor covered grills. My only complaint is that I didn't receive clear directions on where to go and it's several really big buildings. Other than that I would highly recommend it and would stay there again."
United States
Michael
$220 nightly
The price is $238
Nov 16 - Nov 17
Total with taxes and fees
Elegant 2BD Escape | Prime Location near DT GVL
A living room with a dark sofa, a coffee table, a lamp, and a flat-screen TV mounted on the wall.

10. Cozy Apt. Near Downtown (2BR, 1BA, 3 beds)

Cozy Apt. Near Downtown (2BR, 1BA, 3 beds)
Greenville
10.0 out of 10, Exceptional, (14 reviews)
"I was provided everything I needed."
United States
Pat
$144 nightly
The price is $159
Nov 17 - Nov 18
Total with taxes and fees
Cozy Apt. Near Downtown (2BR, 1BA, 3 beds)
A modern kitchen with a stainless steel refrigerator, a microwave, and a sink. There is a wooden dining table with chairs and a laundry basket labeled "laundry" in the foreground.

11. 2BR 2Bath - Swamp Rabbit Trail Resort

2BR 2Bath - Swamp Rabbit Trail Resort
Greenville
9.2 out of 10, Wonderful, (46 reviews)
"Great place!"
United States
Lisa W.
$168 nightly
The price is $185
Nov 15 - Nov 16
Total with taxes and fees
2BR 2Bath - Swamp Rabbit Trail Resort
A modern living room with a sectional sofa, a dining area with chairs, and a large bean bag.

12. Red Door Apartment 2.0 | Heart Of Downtown Greenville | Lovesac Bean Bag!

Red Door Apartment 2.0 | Heart Of Downtown Greenville | Lovesac Bean Bag!
Greenville Downtown
9.4 out of 10, Exceptional, (92 reviews)
"Best communication ever!!! Lovely apartment with close vicinity to great restaurants and enjoyable venues. Would stay again."
United States
Angela
$316 nightly
The price is $348
Nov 18 - Nov 19
Total with taxes and fees
Red Door Apartment 2.0 | Heart Of Downtown Greenville | Lovesac Bean Bag!
A courtyard with trees, a brick building, and a modern glass building.

13. Modern Condo in the Heart of Downtown Greenville

Modern Condo in the Heart of Downtown Greenville
Greenville Downtown
9.8 out of 10, Exceptional, (150 reviews)
"Great location."
United States
Tammy D.
$326 nightly
The price is $359
Nov 29 - Nov 30
Total with taxes and fees
Modern Condo in the Heart of Downtown Greenville
A modern kitchen with granite countertops, stainless steel appliances, and a dining area with a sofa and table.

14. 2BR Cedar Lane Road Retreat at Swamp Rabbit Trail!

2BR Cedar Lane Road Retreat at Swamp Rabbit Trail!
Greenville
9.4 out of 10, Exceptional, (41 reviews)
"The area is very quiet, a wonderful space, excellent service."
United States
Gabriel D.
$168 nightly
The price is $185
Nov 15 - Nov 16
Total with taxes and fees
2BR Cedar Lane Road Retreat at Swamp Rabbit Trail!
There is a beautiful common space guests are welcome to enjoy.

15. Luxury 1-bedroom apartment with pool

Luxury 1-bedroom apartment with pool
Greenville
9.6 out of 10, Exceptional, (21 reviews)
"The unit was clean and comfortable. Accurate directions lead to the right spot and has easy access to the unit. I enjoyed my stay here and was the perfect location for me. Thank you."
United States
Daniel S.
$163 nightly
The price is $172
Nov 19 - Nov 20
Total with taxes and fees
Luxury 1-bedroom apartment with pool
A modern living room with a grey sofa, a round coffee table, and a dining area with a table and chairs.

16. Southern Charm Townhome

Southern Charm Townhome
Simpsonville
10.0 out of 10, Exceptional, (11 reviews)
"Excellent stay and a very attentive, kind hearted host. Wonderful experience...will stay with this host again."
United States
Roger S.
$372 nightly
The price is $423
Nov 17 - Nov 18
Total with taxes and fees
Southern Charm Townhome
A spacious living area with wooden flooring, a sofa, a coffee table, and a dining table with candles.

17. GORGEOUS 2 BR on MAIN #1

GORGEOUS 2 BR on MAIN #1
Greenville Downtown
9.6 out of 10, Exceptional, (17 reviews)
"Excellent view, and everything we needed was within walking distance. A must stay for anyone in the Greenville area."
United States
Ryan R.
$335 nightly
The price is $368
Nov 19 - Nov 20
Total with taxes and fees
GORGEOUS 2 BR on MAIN #1
Room

18. Carolina Camp Cedar

Carolina Camp Cedar
3.5 star property
Pickens
10.0 out of 10, Exceptional, (5 reviews)
"The cottage was clean, staff was so friendly, our stay was quiet and peaceful… it was perfect! Definitely planning to stay there again!"
United States
Katlynn
$177 nightly
The price is $197
Nov 19 - Nov 20
Total with taxes and fees
Carolina Camp Cedar
A living room with a brick wall, leather sofas, a wooden coffee table, and a fireplace.

19. Trio Loft | D-Town GVL | 65" TV + Indoor Fireplace

Trio Loft | D-Town GVL | 65" TV + Indoor Fireplace
Greenville Downtown
9.6 out of 10, Exceptional, (77 reviews)
"Great Location Location Location !"
United States
Chris H.
$304 nightly
The price is $335
Nov 15 - Nov 16
Total with taxes and fees
Trio Loft | D-Town GVL | 65" TV + Indoor Fireplace
A house with a gravel driveway, a wooden fence, and a lawn.

20. Secluded Tiny Home in Exclusive Paris Mountain!

Secluded Tiny Home in Exclusive Paris Mountain!
Greenville
10.0 out of 10, Exceptional, (15 reviews)
"Great location, quiet and perfect for a couple stay. "
United States
craig d.
$116 nightly
The price is $128
Nov 15 - Nov 16
Total with taxes and fees
Secluded Tiny Home in Exclusive Paris Mountain!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Upstate South Carolina Hotel Reviews

Best Western Plus Greenville I-385 Inn & Suites

Best Western Plus Greenville I-385 Inn & Suites

10/10 Excellent
"I was expecting the standard Best Western hotel and room. Wow, was I surprised! This hotel exceeded my expectations in every way! From the size of the room, to the comfort of the bed, to the excellent breakfast that was included - it was better in every aspect. We were only staying one night, but I know that if we are ever in the area again and need a place to stay, I will definitely be contacting the Best Western-Plus Greenville I-385 Inn & Suites."
Katherine 1-night trip
Posted 7 hours ago
Best Western Plus Greenville I-385 Inn & Suites

Find out more about Upstate South Carolina

Everything you need to know about Upstate South Carolina vacation rentals

Whether you’re excited for the perfect family vacation, a romantic getaway for two, or the ultimate city break, we’ve got the Upstate South Carolina vacation rental for you. At Expedia, you can take your pick from private vacation homes, apartments, condos, resorts, cabins, villas, motels. The list goes on, and on …and on.

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Upstate South Carolina vacation rental for you by simply entering your desired dates. Then check your favorite filters to narrow down your search.

Upstate South Carolina vacation rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Upstate South Carolina. If you’re looking for a little peace, consider booking during the quieter low season months. For more hustle and bustle, you may prefer to visit Upstate South Carolina in high season.

Prices vary throughout the year. Your chosen location, property type, and amenities will impact the cost of your trip, too. The selection of properties we have chosen for you start as low as $56 per night. Rates vary depending on your travel dates, location, and amenities so make a search and you might find even better deals!

How to find incredible deals on Upstate South Carolina rentals

At Expedia, we put the best Upstate South Carolina vacation rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia.

To find some top Upstate South Carolina rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Upstate South Carolina vacation.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Upstate South Carolina. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.

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