$112 Cheap Flights from Indianapolis (IND) to Knoxville (TYS)

View $112 flight on Wed, Dec 31, 2025Opens in a new window

Popular airlines from Indianapolis Intl. Airport (IND) to McGhee Tyson Airport (TYS)

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Cheap Flights from Indianapolis to Knoxville (IND-TYS)

Prices were available within the past 7 days and start at $112 for one-way flights and $223 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Thu, Jan 1 - Tue, Jan 20
IND
Indianapolis
TYS
Knoxville
$223 Roundtrip, found 1 hour ago
$223
Roundtrip
found 1 hour ago
Select Delta flight, departing Thu, Jan 1 from Indianapolis to Knoxville, returning Tue, Jan 20, priced at $223 found 1 hour ago
American Airlines
Sat, Jan 17 - Sun, Jan 18
IND
Indianapolis
TYS
Knoxville
$237 Roundtrip, found 11 hours ago
$237
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Sat, Jan 17 from Indianapolis to Knoxville, returning Sun, Jan 18, priced at $237 found 11 hours ago
Delta
Mon, Feb 2 - Wed, Feb 18
IND
Indianapolis
TYS
Knoxville
$247 Roundtrip, found 1 hour ago
$247
Roundtrip
found 1 hour ago
Select Delta flight, departing Mon, Feb 2 from Indianapolis to Knoxville, returning Wed, Feb 18, priced at $247 found 1 hour ago
Delta
Tue, Feb 10 - Tue, Feb 24
IND
Indianapolis
TYS
Knoxville
$251 Roundtrip, found 1 hour ago
$251
Roundtrip
found 1 hour ago
Select Delta flight, departing Tue, Feb 10 from Indianapolis to Knoxville, returning Tue, Feb 24, priced at $251 found 1 hour ago
United
Sat, Jan 17 - Sun, Jan 18
IND
Indianapolis
TYS
Knoxville
$253 Roundtrip, found 11 hours ago
$253
Roundtrip
found 11 hours ago
Select United flight, departing Sat, Jan 17 from Indianapolis to Knoxville, returning Sun, Jan 18, priced at $253 found 11 hours ago
Delta
Sun, Jan 18 - Tue, Jan 20
IND
Indianapolis
TYS
Knoxville
$255 Roundtrip, found 6 days ago
$255
Roundtrip
found 6 days ago
Select Delta flight, departing Sun, Jan 18 from Indianapolis to Knoxville, returning Tue, Jan 20, priced at $255 found 6 days ago
Delta
Thu, Feb 5 - Tue, Feb 24
IND
Indianapolis
TYS
Knoxville
$261 Roundtrip, found 1 hour ago
$261
Roundtrip
found 1 hour ago
Select Delta flight, departing Thu, Feb 5 from Indianapolis to Knoxville, returning Tue, Feb 24, priced at $261 found 1 hour ago
Delta
Wed, Jan 14 - Thu, Jan 15
IND
Indianapolis
TYS
Knoxville
$265 Roundtrip, found 1 day ago
$265
Roundtrip
found 1 day ago
Select Delta flight, departing Wed, Jan 14 from Indianapolis to Knoxville, returning Thu, Jan 15, priced at $265 found 1 day ago
American Airlines
Sat, Jan 17 - Sun, Jan 18
IND
Indianapolis
TYS
Knoxville
$267 Roundtrip, found 11 hours ago
$267
Roundtrip
found 11 hours ago
Select American Airlines flight, departing Sat, Jan 17 from Indianapolis to Knoxville, returning Sun, Jan 18, priced at $267 found 11 hours ago
Southwest Airlines
Wed, Mar 11 - Mon, Mar 16
IND
Indianapolis
TYS
Knoxville
$284 Roundtrip, found 2 days ago
$284
Roundtrip
found 2 days ago
Select Southwest Airlines flight, departing Wed, Mar 11 from Indianapolis to Knoxville, returning Mon, Mar 16, priced at $284 found 2 days ago

Find the cheapest month to fly from Indianapolis (IND) to Knoxville (TYS)

April is typically the cheapest month to fly

From $198 - $480 per traveler.

Alternative airports near Knoxville

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to McGhee Tyson TYS. Cheapest and Closest option available. Average driving time to city center is 22 minutes. Flights from $320
TYS
McGhee Tyson
CheapestClosest
Average driving time to city center22 min
Flights from $320

Frequently asked questions

How much does a flight from Indianapolis Intl. Airport (IND) to McGhee Tyson Airport (TYS) cost?
Secure a cheap one-way flight from $112 or cheap return flight from $223 from Indianapolis Intl. Airport (IND) to McGhee Tyson Airport (TYS) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to find our cheapest flight offers on this route.
What is the cheapest month to fly from Indianapolis Intl. Airport (IND) to McGhee Tyson Airport (TYS)?
The cheapest month to fly from IND to TYS is January, when there's less demand. Off-peak season is typically when airlines offer lower prices between these airports.
What is the cheapest airline that flies from Indianapolis Intl. Airport (IND) to McGhee Tyson Airport (TYS)?
To find the cheapest airline flying from IND to TYS, use Expedia's filter tool. Customize your search based on what's important to you, such as preferred carriers and ideal departure window. You can then sort your results by "Price (lowest to highest)" to discover the cheapest flight right away.
How many flights per day from Indianapolis Intl. Airport (IND) to McGhee Tyson Airport (TYS)?
There aren't any daily nonstop flights departing from Indianapolis Intl. Airport (IND) to McGhee Tyson Airport (TYS). But you can choose flights with layovers. Filter your search on Expedia to include one or more stops, and you'll be on your way in no time at all.
What day of the week has the most flights from IND to TYS?
Friday is generally the busiest day for flights, while Tuesday is often the quietest.* Remember that flight schedules can vary based on a range of factors, including the time of year and carrier.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Indianapolis Intl. Airport (IND) to McGhee Tyson Airport (TYS)?
Select a flight from Indianapolis Intl. Airport (IND) to McGhee Tyson Airport (TYS) that leaves before 3 PM to reduce the risk of delays and cancellations. Departures after this hour have a 22% higher chance of being canceled, on average.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Indianapolis Intl. Airport (IND) to McGhee Tyson Airport (TYS) last-minute?
Last-minute bookings from IND to TYS are generally more expensive. For the cheapest rates, start looking for flights as soon as possible. That being said, if your travel plans are flexible, it's possible to find a cheap fare right before your journey.
Is it cheaper to book an IND to TYS flight and hotel package?
Booking an IND to TYS flight and hotel package is typically cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels in one place. Select from our wide range of stays and then add flights, activities and car rentals to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Indianapolis Intl. Airport (IND) to McGhee Tyson Airport (TYS)?
In most cases, you can cancel or modify your IND to TYS flight. However, there may be additional charges, especially if your booking was made more than 24 hours ago. Double-check your itinerary for the airline's policies and fees on flight changes, or if you need further information, head to our Customer Service portal.

Travel information

Origin airport
Indianapolis Intl.
Destination airport
McGhee Tyson
Airlines serving
American Airlines, Delta, Southwest Airlines, United
Roundtrip price
$222
Distance
298 mi

Book with confidence

Indianapolis to Knoxville Flights

The cheapest times to fly from Indianapolis to Knoxville

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Indianapolis to Knoxville are during the month of January. You can find some of the cheapest flights from Indianapolis to Knoxville with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Indianapolis to Knoxville

Sunday is one of the best days to book for cheap flights from Indianapolis to Knoxville: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Indianapolis to Knoxville

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Indianapolis to Knoxville in 2026. You can also book with separate airlines for your outbound and return journeys, from $112 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Indianapolis to Knoxville flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Indianapolis to Knoxville airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Indianapolis to Knoxville Flights

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