$108 Cheap Flights from Myrtle Beach (MYR) to Panama City (ECP)

View $108 flight on Wed, Dec 10, 2025Opens in a new window

Popular airlines from Myrtle Beach Intl. Airport (MYR) to Northwest Florida Beaches Intl. Airport (ECP)

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Cheap Flights from Myrtle Beach to Panama City (MYR-ECP)

Prices were available within the past 7 days and start at $108 for one-way flights and $215 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Delta
Tue, Nov 4 - Wed, Nov 12
MYR
Myrtle Beach
ECP
Panama City
$215 Roundtrip, found 2 hours ago
$215
Roundtrip
found 2 hours ago
Select Delta flight, departing Tue, Nov 4 from Myrtle Beach to Panama City, returning Wed, Nov 12, priced at $215 found 2 hours ago
American Airlines
Wed, Dec 10 - Mon, Dec 15
MYR
Myrtle Beach
ECP
Panama City
$229 Roundtrip, found 1 day ago
$229
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Dec 10 from Myrtle Beach to Panama City, returning Mon, Dec 15, priced at $229 found 1 day ago
Delta
Tue, Dec 9 - Wed, Dec 24
MYR
Myrtle Beach
ECP
Panama City
$236 Roundtrip, found 2 days ago
$236
Roundtrip
found 2 days ago
Select Delta flight, departing Tue, Dec 9 from Myrtle Beach to Panama City, returning Wed, Dec 24, priced at $236 found 2 days ago
American Airlines
Mon, Nov 3 - Mon, Nov 10
MYR
Myrtle Beach
ECP
Panama City
$243 Roundtrip, found 2 hours ago
$243
Roundtrip
found 2 hours ago
Select American Airlines flight, departing Mon, Nov 3 from Myrtle Beach to Panama City, returning Mon, Nov 10, priced at $243 found 2 hours ago
Delta
Mon, Nov 3 - Mon, Nov 10
MYR
Myrtle Beach
ECP
Panama City
$246 Roundtrip, found 2 hours ago
$246
Roundtrip
found 2 hours ago
Select Delta flight, departing Mon, Nov 3 from Myrtle Beach to Panama City, returning Mon, Nov 10, priced at $246 found 2 hours ago
Delta
Thu, Jan 1 - Sat, Jan 17
MYR
Myrtle Beach
ECP
Panama City
$257 Roundtrip, found 2 days ago
$257
Roundtrip
found 2 days ago
Select Delta flight, departing Thu, Jan 1 from Myrtle Beach to Panama City, returning Sat, Jan 17, priced at $257 found 2 days ago
Southwest Airlines
Fri, Oct 24 - Wed, Oct 29
MYR
Myrtle Beach
ECP
Panama City
$257 Roundtrip, found 1 day ago
$257
Roundtrip
found 1 day ago
Select Southwest Airlines flight, departing Fri, Oct 24 from Myrtle Beach to Panama City, returning Wed, Oct 29, priced at $257 found 1 day ago
American Airlines
Wed, Dec 10 - Mon, Dec 15
MYR
Myrtle Beach
ECP
Panama City
$259 Roundtrip, found 1 day ago
$259
Roundtrip
found 1 day ago
Select American Airlines flight, departing Wed, Dec 10 from Myrtle Beach to Panama City, returning Mon, Dec 15, priced at $259 found 1 day ago
American Airlines
Fri, Oct 24 - Wed, Oct 29
MYR
Myrtle Beach
ECP
Panama City
$260 Roundtrip, found 1 day ago
$260
Roundtrip
found 1 day ago
Select American Airlines flight, departing Fri, Oct 24 from Myrtle Beach to Panama City, returning Wed, Oct 29, priced at $260 found 1 day ago
Delta
Tue, Nov 4 - Tue, Nov 11
MYR
Myrtle Beach
ECP
Panama City
$266 Roundtrip, found 2 hours ago
$266
Roundtrip
found 2 hours ago
Select Delta flight, departing Tue, Nov 4 from Myrtle Beach to Panama City, returning Tue, Nov 11, priced at $266 found 2 hours ago

Find the cheapest month to fly from Myrtle Beach (MYR) to Panama City (ECP)

September is typically the cheapest month to fly

From $196 - $507 per traveler.

Alternative airports near Panama City

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Northwest Florida Beaches Intl. ECP. Cheapest and Closest option available. Average driving time to city center is 35 minutes. Flights from $464
ECP
Northwest Florida Beaches Intl.
CheapestClosest
Average driving time to city center35 min
Flights from $464

Frequently asked questions

How much does a flight from Myrtle Beach Intl. Airport (MYR) to Northwest Florida Beaches Intl. Airport (ECP) cost?
Secure a cheap one-way flight from $108 or cheap return flight from $215 from Myrtle Beach Intl. Airport (MYR) to Northwest Florida Beaches Intl. Airport (ECP) with Expedia. Enter your travel dates and sort by "Price (lowest to highest)" to see our cheapest flight offers on this route.
What is the cheapest month to fly from Myrtle Beach Intl. Airport (MYR) to Northwest Florida Beaches Intl. Airport (ECP)?
Planning your getaway for November is a great way to save, as it's the cheapest month for flights between MYR and ECP. You'll usually find the lowest fares during the off-season.
What is the cheapest airline that flies from Myrtle Beach Intl. Airport (MYR) to Northwest Florida Beaches Intl. Airport (ECP)?
To find the cheapest airline flying from MYR to ECP, use Expedia's filter tool. Customize your search based on your travel needs, such as preferred carriers and number of stops. You can then sort your results by "Price (lowest to highest)" to discover the cheapest flight right away.
How many flights per day from Myrtle Beach Intl. Airport (MYR) to Northwest Florida Beaches Intl. Airport (ECP)?
Direct flights from Myrtle Beach Intl. Airport (MYR) to Northwest Florida Beaches Intl. Airport (ECP) aren't available daily, so you'll have to take a flight with a layover. Explore your options with Expedia's filter tool. Enter your dates and click on either "1 Stop" or "2+ Stops."
What day of the week has the most flights from MYR to ECP?
Friday is typically the busiest day for flights, while Tuesday is often the quietest.* Remember that flight schedules can change depending on a range of factors, including the time of year and carrier.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Myrtle Beach Intl. Airport (MYR) to Northwest Florida Beaches Intl. Airport (ECP)?
To arrive at Northwest Florida Beaches Intl. Airport (ECP) on schedule, choose a flight that takes off from Myrtle Beach Intl. Airport (MYR) before 3 PM. The likelihood of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
Is it cheaper to buy a plane ticket from Myrtle Beach Intl. Airport (MYR) to Northwest Florida Beaches Intl. Airport (ECP) last-minute?
Waiting until right before your break to book your flight from MYR to ECP generally means paying more. While you may find some last-minute offers, they aren't always guaranteed. Be flexible with your itinerary to boost your chances of landing a bargain.
Is it cheaper to book a MYR to ECP flight and hotel package?
Securing a MYR to ECP flight and hotel package tends to be cheaper than booking separately. With Expedia, you can enjoy the ease of organizing your travels in one place. Choose from our impressive range of hotels and then add flights, car rentals and activities to your booking. Bundle it all together, and you could save hundreds of dollars.
Can I cancel or change the date of my flight from Myrtle Beach Intl. Airport (MYR) to Northwest Florida Beaches Intl. Airport (ECP)?
If you booked your MYR to ECP flight within the last 24 hours, you may be able to cancel or modify it without fees. Depending on the airline and the fare type you purchased, additional charges may apply for changes beyond that time. Airline policies and contact information can be found in your itinerary or confirmation email. Or, head to our Customer Service portal for more details.

Travel information

Travel information

Origin airport
Myrtle Beach Intl.
Destination airport
Northwest Florida Beaches Intl.
Airlines serving
American Airlines, Delta, Southwest Airlines
Roundtrip price
$214
Distance
463 mi
Average flight time
3 hours 35 mins

Book with confidence

Book with confidence

Myrtle Beach to Panama City Flights

The cheapest times to fly from Myrtle Beach to Panama City

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Myrtle Beach to Panama City are during the month of November. You can find some of the cheapest flights from Myrtle Beach to Panama City with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Myrtle Beach to Panama City

Sunday is one of the best days to book for cheap flights from Myrtle Beach to Panama City: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Myrtle Beach to Panama City

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Myrtle Beach to Panama City in 2025. You can also book with separate airlines for your outbound and return journeys, from $108 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Myrtle Beach to Panama City flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Myrtle Beach to Panama City airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Myrtle Beach to Panama City Flights

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