$41 Cheap Flights from Pisa (PSA) to Brussels (BRU)

View $41 flight on Sun, Sep 7, 2025Opens in a new window

Popular airlines from Galileo Galilei Airport (PSA) to Brussels Airport (BRU)

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Cheap Flights from Pisa to Brussels (PSA-BRU)

Prices were available within the past 7 days and start at $41 for one-way flights and $78 for round trip, for the period specified. Prices and availability are subject to change. Additional terms apply.

Ryanair
Wed, Sep 3 - Mon, Sep 22
PSA
Pisa
BRU
Brussels
$78 Roundtrip, found 22 hours ago
$78
Roundtrip
found 22 hours ago
Select Ryanair flight, departing Wed, Sep 3 from Pisa to Brussels, returning Mon, Sep 22, priced at $78 found 22 hours ago
Ryanair
Wed, Aug 27 - Mon, Sep 1
PSA
Pisa
BRU
Brussels
$83 Roundtrip, found 2 days ago
$83
Roundtrip
found 2 days ago
Select Ryanair flight, departing Wed, Aug 27 from Pisa to Brussels, returning Mon, Sep 1, priced at $83 found 2 days ago
Ryanair
Wed, Aug 27 - Sun, Aug 31
PSA
Pisa
BRU
Brussels
$88 Roundtrip, found 2 days ago
$88
Roundtrip
found 2 days ago
Select Ryanair flight, departing Wed, Aug 27 from Pisa to Brussels, returning Sun, Aug 31, priced at $88 found 2 days ago
Ryanair
Wed, Sep 10 - Sun, Sep 14
PSA
Pisa
BRU
Brussels
$101 Roundtrip, found 1 day ago
$101
Roundtrip
found 1 day ago
Select Ryanair flight, departing Wed, Sep 10 from Pisa to Brussels, returning Sun, Sep 14, priced at $101 found 1 day ago
Lufthansa
Thu, Oct 9 - Sun, Oct 12
PSA
Pisa
BRU
Brussels
$198 Roundtrip, found 1 day ago
$198
Roundtrip
found 1 day ago
Select Lufthansa flight, departing Thu, Oct 9 from Pisa to Brussels, returning Sun, Oct 12, priced at $198 found 1 day ago
British Airways
Thu, Oct 9 - Sun, Oct 12
PSA
Pisa
BRU
Brussels
$375 Roundtrip, found 1 day ago
$375
Roundtrip
found 1 day ago
Select British Airways flight, departing Thu, Oct 9 from Pisa to Brussels, returning Sun, Oct 12, priced at $375 found 1 day ago
Aer Lingus
Thu, Sep 11 - Thu, Sep 18
PSA
Pisa
BRU
Brussels
$478 Roundtrip, found 2 days ago
$478
Roundtrip
found 2 days ago
Select Aer Lingus flight, departing Thu, Sep 11 from Pisa to Brussels, returning Thu, Sep 18, priced at $478 found 2 days ago
Scandinavian Airlines
Sat, Aug 16 - Wed, Aug 20
PSA
Pisa
BRU
Brussels
$485 Roundtrip, found 15 hours ago
$485
Roundtrip
found 15 hours ago
Select Scandinavian Airlines flight, departing Sat, Aug 16 from Pisa to Brussels, returning Wed, Aug 20, priced at $485 found 15 hours ago
Air Baltic
Fri, Oct 10 - Sun, Oct 12
PSA
Pisa
BRU
Brussels
$669 Roundtrip, found 1 day ago
$669
Roundtrip
found 1 day ago
Select Air Baltic flight, departing Fri, Oct 10 from Pisa to Brussels, returning Sun, Oct 12, priced at $669 found 1 day ago

Alternative airports near Brussels

Prices were available within the past 7 days. Prices and availability are subject to change.

Select flight to Brussels South Charleroi CRL. Average driving time to city center is 42 minutes. Flights from $208
CRL
Brussels South Charleroi
Average driving time to city center42 min
Flights from $208
Flights from Pisa (PSA) to Charleroi (CRL)
Origin airport
Galileo Galilei
Destination airport
Brussels South Charleroi
Airlines serving
British Airways, Lufthansa, Ryanair, Scandinavian Airlines
Roundtrip price
$67
Distance
543 mi
Average flight time
1 hour 50 mins

Pisa to Brussels Flights

The cheapest times to fly from Pisa to Brussels

On average, Thursday can be the cheapest time to fly, according to data from the Airlines Reporting Corporation (ARC), one of the world's biggest databases for global airline sales. The data reveals that you could save up to 16% by flying on a Thursday—the cheapest day to travel on average—instead of a Sunday—the most expensive. Some of the most affordable flights from Pisa to Brussels are during the month of September. You can find some of the cheapest flights from Pisa to Brussels with Expedia's search tool and vast selection of airlines.

 

The best time to book a flight from Pisa to Brussels

Sunday is one of the best days to book for cheap flights from Pisa to Brussels: Tickets reserved on a Sunday cost between 6% and 13% less than those reserved on a Friday, according to ARC data. The data also suggests booking early can also lead to cheaper airfares. You could save 24% by buying your tickets for domestic flights at least a month in advance and 10% by booking international flights 2 months in advance.

 

How to find cheap round-trip tickets from Pisa to Brussels

Being flexible with your dates and using Expedia's Price Drop Protection and Price Tracking features are some of the best ways of finding a cheap ticket from Pisa to Brussels in 2025. You can also book with separate airlines for your outbound and return journeys, from $41 one-way. Expedia also offers Price Drop Protection, so if the cost of your airfare goes down after booking, you'll receive a credit for the difference*. This is available for a small fee, and is free to One Key Gold and Platinum tier members.

 

Expedia's Price Tracking feature means you can stay on top of airfares without manually checking every day. It sends you automated price alerts for cheap Pisa to Brussels flights and uses historical data to indicate when the best time to book is. Download Expedia's free app to activate this handy tool in a few easy taps.

 

You could also save big by booking one of Expedia's vacation packages. Bundling together your Pisa to Brussels airfare with your accommodations and car rental is often cheaper than booking everything separately. There’s also One Key, Expedia's generous rewards program. Join for free and you could earn One Key cash on most bookings to save on future adventures.

 

*Terms apply.

 

Disclaimer: ARC The statistics are based on average round-trip ticket prices between January and August 2023. The percentages you see are averages.

 

Frequently asked questions

How much does a flight from Galileo Galilei Airport (PSA) to Brussels - National Airport (BRU) cost?
Snag cheap return fares starting from $91 from Galileo Galilei Airport (PSA) to Brussels - National Airport (BRU). This information is based on the cheapest price found on Expedia for this return journey departing within the next three months. This airfare is for a Ryanair flight leaving PSA on August 10 2025 and touching down at BRU. The price was last updated on July 23 2025 and has not changed since.
What is the cheapest month to fly from PSA to BRU?
The cheapest flights from PSA to BRU are usually during off-peak season, when demand is lower. To save money, avoid flying during public holidays, school breaks and major local events.
What is the cheapest airline that flies from PSA to BRU?
With prices starting from $41 for a one-way flight from PSA to BRU, Ryanair is currently the cheapest carrier flying this route. This fare is based on the lowest price found on Expedia departing within the next three months. The flight takes off from PSA on July 27 2025. Prices were last updated on July 23 2025 and have not changed since.
How many flights per day from Galileo Galilei Airport (PSA) to Brussels - National Airport (BRU)?
Direct flights from Galileo Galilei Airport (PSA) to Brussels - National Airport (BRU) aren't available daily, so you'll have to take a flight with a layover. Explore your options with Expedia's filter tool. Enter your travel dates and pick either "1 Stop" or "2+ Stops."
What day of the week has the most flights from PSA to BRU?
Generally you'll have the most choice when it comes to flights on a Friday. Tuesdays are often the quietest.* However, this can vary depending on the airline, time of year and other factors.*Busiest/quietest day to travel is based on Expedia flight demand through January to December 2024.
What is the best time to fly from Galileo Galilei Airport (PSA) to Brussels - National Airport (BRU)?
To arrive at Brussels - National Airport (BRU) on schedule, opt for a flight that takes off from Galileo Galilei Airport (PSA) before 3 PM. The chance of cancellations is 22% higher, on average, for departures after this time.**Most reliable time of the day and month to travel recommendation is based on January through August 2024 flight status data sourced from OAG's global flight data platform.
What airports do you fly into for Brussels from Galileo Galilei Airport (PSA)?
If you're traveling on a direct flight from Galileo Galilei Airport (PSA) to Brussels, Brussels South Charleroi Airport (CRL) is the only airport you can land at.
Is it cheaper to buy a plane ticket from Galileo Galilei Airport (PSA) to Brussels - National Airport (BRU) last-minute?
Waiting until just before your trip to book a flight from PSA to BRU often results in higher prices. While it's possible to find some last-minute discounts, they're not always guaranteed. Keep your travel plans flexible for a better chance of snagging a bargain.
Is it cheaper to book a PSA to BRU flight and hotel package?
You'll generally save money by securing a PSA to BRU flight and hotel package compared to booking separately. In fact, travelers could save hundreds of dollars by bundling with Expedia. And it's simple to manage it all in one place. After choosing your preferred accommodations and flights, you can add extras like car rentals, activities and tours.
Can I cancel or change the date of my flight from Galileo Galilei Airport (PSA) to Brussels - National Airport (BRU)?
If you reserved your PSA to BRU flight in the last 24 hours, you may be able to cancel or modify it at no cost. Depending on the airline and the type of ticket you purchased, additional charges may apply for changes beyond this timeframe. Airline policies and contact information can be found in your itinerary or confirmation email. Or, go to our Customer Service portal if you want more information.

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