Find 4 Star Hotels in Otay Mesa West, CA from $131

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Dec 6 - Dec 7
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Dec 7 - Dec 8
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Dec 12 - Dec 14
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Dec 19 - Dec 21

Compare Otay Mesa West 4 Star Hotels with updated room rates, reviews, and availability. Most hotels are fully refundable.

Lobby
Hotel del Coronado, Curio Collection by Hilton

Hotel del Coronado, Curio Collection by Hilton

4.0 star property
Historic Downtown Coronado
8.4 out of 10, Very Good, (1003)
"Beautiful rooms, great activities, wonderful staff "
United States
Kyle
$389 nightly
The price is $432
Jan 4 - Jan 5, 2026
Total with taxes and fees
Hotel del Coronado, Curio Collection by Hilton
Outdoor pool
Hard Rock Hotel San Diego

Hard Rock Hotel San Diego

4.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (3138)
"Great stay"
United States
Laurence
$210 nightly
The price is $243
Jan 1 - Jan 2, 2026
Total with taxes and fees
Hard Rock Hotel San Diego
Daily buffet breakfast for a fee
DoubleTree by Hilton Hotel San Diego - Mission Valley

DoubleTree by Hilton Hotel San Diego - Mission Valley

4.0 star property
Mission Valley
8.4 out of 10, Very Good, (1382)
"Great hotel in a great area - would definitely stay here again."
United States
Bhupinder
$114 nightly
The price is $131
Dec 14 - Dec 15
Total with taxes and fees
DoubleTree by Hilton Hotel San Diego - Mission Valley
City view from property
Courtyard by Marriott San Diego Downtown Little Italy

Courtyard by Marriott San Diego Downtown Little Italy

4.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (78)
"It was a nice place to stay at"
United States
Eric
$118 nightly
The price is $137
Dec 14 - Dec 15
Total with taxes and fees
Courtyard by Marriott San Diego Downtown Little Italy
Lobby
Hilton San Diego Mission Valley

Hilton San Diego Mission Valley

4.0 star property
Mission Valley
8.0 out of 10, Very Good, (2226)
"Excelente hotel"
Mexico
Julio
$118 nightly
The price is $136
Dec 13 - Dec 14
Total with taxes and fees
Hilton San Diego Mission Valley
Garden
Legacy Resort Hotel & Spa

Legacy Resort Hotel & Spa

4.0 star property
Mission Valley
9.2 out of 10, Wonderful, (2948)
"Friendly, staff was very helpful, great size rooms, and over all was an amazing stay"
United States
Naya
$152 nightly
The price is $175
Dec 7 - Dec 8
Total with taxes and fees
Legacy Resort Hotel & Spa
Terrace/patio
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4.0 star property
Downtown San Diego
8.4 out of 10, Very Good, (6068)
"Always an amazing stay"
United States
Jana
$160 nightly
The price is $186
Dec 9 - Dec 10
Total with taxes and fees
Wyndham San Diego Bayside
Lobby
Embassy Suites by Hilton San Diego Bay Downtown

Embassy Suites by Hilton San Diego Bay Downtown

4.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (1538)
"Clean room, friendly staff, great property. "
United States
MIGUEL
$197 nightly
The price is $228
Dec 23 - Dec 24
Total with taxes and fees
Embassy Suites by Hilton San Diego Bay Downtown
Outdoor pool, open 7:00 AM to 9:00 PM, cabanas (surcharge)
Lafayette Hotel & Club

Lafayette Hotel & Club

4.0 star property
University Heights
9.4 out of 10, Exceptional, (1312)
"Loved everything, I could stay there forever"
United States
Mariana
$226 nightly
The price is $259
Dec 9 - Dec 10
Total with taxes and fees
Lafayette Hotel & Club
Outdoor pool
Sheraton Mission Valley San Diego Hotel

Sheraton Mission Valley San Diego Hotel

4.0 star property
Mission Valley
8.6 out of 10, Excellent, (1645)
"The room was a great size and super clean, the staff is super nice "
United States
Ligia
$118 nightly
The price is $136
Dec 11 - Dec 12
Total with taxes and fees
Sheraton Mission Valley San Diego Hotel
Meeting facility
The Westin San Diego Bayview

The Westin San Diego Bayview

4.0 star property
Downtown San Diego
8.6 out of 10, Excellent, (1049)
"I loved the hotel rooms bar area jacuzzi area everything was great it was in a pretty location will definitely come back "
United States
Alliyah
$160 nightly
The price is $186
Dec 19 - Dec 20
Total with taxes and fees
The Westin San Diego Bayview
Hypo-allergenic bedding, in-room safe, desk, iron/ironing board
Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (2869)
"It was nice and the bar up top was great"
United States
Brent
$223 nightly
The price is $259
Dec 14 - Dec 15
Total with taxes and fees
Manchester Grand Hyatt San Diego
2 outdoor pools, open 6 AM to 10:00 PM, cabanas (surcharge)
Marriott Marquis San Diego Marina

Marriott Marquis San Diego Marina

4.0 star property
Downtown San Diego
9.2 out of 10, Wonderful, (1938)
"Great hotel"
United States
Farzana
$204 nightly
The price is $237
Dec 18 - Dec 19
Total with taxes and fees
Marriott Marquis San Diego Marina
Exterior
Margaritaville Hotel San Diego Gaslamp Quarter

Margaritaville Hotel San Diego Gaslamp Quarter

4.0 star property
Downtown San Diego
9.0 out of 10, Wonderful, (1157)
"Amenities and location were great. "
United States
Julie
$198 nightly
The price is $229
Dec 25 - Dec 26
Total with taxes and fees
Margaritaville Hotel San Diego Gaslamp Quarter
Property amenity
San Diego Marriott Mission Valley

San Diego Marriott Mission Valley

4.0 star property
Mission Valley
8.8 out of 10, Excellent, (1001)
"Great location, hotel is under construction so part of the hotel is completely closed off for construction. "
United States
Amama
$139 nightly
The price is $160
Dec 14 - Dec 15
Total with taxes and fees
San Diego Marriott Mission Valley
Lobby sitting area
Omni San Diego Hotel at the Ballpark

Omni San Diego Hotel at the Ballpark

4.0 star property
Downtown San Diego
9.2 out of 10, Wonderful, (2043)
"It was an amazing stay "
United States
Alejandra
$225 nightly
The price is $261
Jan 4 - Jan 5, 2026
Total with taxes and fees
Omni San Diego Hotel at the Ballpark
Suite, 1 King Bed with Sofa Bed (Marina Tower Newly Renovated Marina view) | View from room
Sheraton San Diego Resort

Sheraton San Diego Resort

4.0 star property
Harbor Island
8.2 out of 10, Very Good, (3172)
"Great stay! "
United States
Melissa
$125 nightly
The price is $144
Dec 28 - Dec 29
Total with taxes and fees
Sheraton San Diego Resort
Exterior
InterContinental San Diego by IHG

InterContinental San Diego by IHG

4.0 star property
Downtown San Diego
9.2 out of 10, Wonderful, (1112)
"Excellent location prior to a cruise."
Canada
Joan
$262 nightly
The price is $304
Dec 21 - Dec 22
Total with taxes and fees
InterContinental San Diego by IHG
View from room
Catamaran Resort and Spa

Catamaran Resort and Spa

4.0 star property
Mission Beach
8.6 out of 10, Excellent, (1102)
"Amazing room, phenomenal staff, highly recommend! Favorite hotel in San Diego "
United States
Daniel
$189 nightly
The price is $218
Jan 5 - Jan 6, 2026
Total with taxes and fees
Catamaran Resort and Spa
Property grounds
Paradise Point Resort & Spa

Paradise Point Resort & Spa

4.0 star property
Mission Bay
8.6 out of 10, Excellent, (2346)
"Amazing place!"
United States
Barak Ben
$175 nightly
The price is $202
Dec 8 - Dec 9
Total with taxes and fees
Paradise Point Resort & Spa
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Explore similar 5-star hotels

Many 5-star hotels have the same amenities as 4-star hotels. See all 5-star hotels in Otay Mesa West.
Pendry San Diego

Pendry San Diego

550 J Street San Diego CA
$300 nightly
The price is $348 total per night from Jan 4 to Jan 5
$348 total
Jan 4 - Jan 5, 2026
Total with taxes and fees
9.2/10 Wonderful! (1,000 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top Otay Mesa West Hotel Reviews

Sheraton San Diego Resort

Sheraton San Diego Resort

10/10 Excellent
"Great view."
David 2-night trip
Posted 23 hours ago
Sheraton San Diego Resort

Frequently asked questions

How much does it cost to stay in a 4-star hotel in Otay Mesa West?
With Expedia's filter tool, scoring a terrific deal on a 4-star hotel in Otay Mesa West just got simpler. Start by entering your chosen arrival date and length of your stay. Then sort the results by price and pick a hotel that best suits your style and budget.

  • Search for the lowest price from $318

What's the difference between 5-star and 4-star hotels in Otay Mesa West?
Offering an inviting guest experience and upscale surroundings, 4-star hotels are a wonderful option for your Otay Mesa West break. These types of accommodations generally feature loads of useful amenities that make it a breeze to unpack and recharge — think pillowtop mattresses, restaurants and gyms. Or enjoy even more lavishness at a 5-star hotel designed to pamper with high-end perks and amenities. Round-the-clock concierge service, complimentary toiletries and world-class dining are typically included at these plush retreats.
Does Otay Mesa West have any 4-star all-inclusive resorts?
Finding vacation bliss in Otay Mesa West is as easy as entering your travel dates and destination, and selecting our "All inclusive" filter. Stay and play where just about everything is already taken care of like your accommodations, meals and activities, or go for a standard 4-star resort in or around this leading destination.

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