Photo by Maxwell Hamilton

Find 5 Star Hotels in Isleworth from $139

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Our top choices for Isleworth 5-star hotels

Property entrance
Royal Garden Hotel

Royal Garden Hotel

Royal Garden Hotel
5.0 star property
London City Centre
9.2 out of 10, Wonderful, (1808)
"First class service, great location and ypu'd be crazy not to pay for the breakfast. "
United States
Ed
$210 nightly
The price is $252
Jan 5 - Jan 6, 2026
Total with taxes and fees
Royal Garden Hotel
Spa
Sofitel London Heathrow

Sofitel London Heathrow

Sofitel London Heathrow
5.0 star property
Heathrow Villages
8.8 out of 10, Excellent, (4791)
"Rooms were great and conveniently located. "
United States
Walter Antonio M.
$162 nightly
The price is $194
Dec 23 - Dec 24
Total with taxes and fees
Sofitel London Heathrow
2 restaurants, breakfast, lunch, dinner served; Italian cuisine
100 Queen's Gate Hotel London Kensington, Curio Collection by Hilton

100 Queen's Gate Hotel London Kensington, Curio Collection by Hilton

100 Queen's Gate Hotel London Kensington, Curio Collection by Hilton
5.0 star property
London City Centre
8.6 out of 10, Excellent, (953)
"Staff were amazing, the room was clean, fresh and well equipped, the location perfect for all the museums and we had a great time, the hotel definitely fulfilled all our expectations "
Germany
Richard
$203 nightly
The price is $243
Dec 18 - Dec 19
Total with taxes and fees
100 Queen's Gate Hotel London Kensington, Curio Collection by Hilton
Exterior
Sea Containers London

Sea Containers London

Sea Containers London
5.0 star property
London City Centre
9.4 out of 10, Exceptional, (2249)
"Clean Room, friendly staff, restaurant and bar on site, steam rooms included with stay, nespresso machine in rooms"
United States
Kollette
$222 nightly
The price is $266
Jan 9 - Jan 10, 2026
Total with taxes and fees
Sea Containers London
Lobby
Hyatt Regency London The Churchill

Hyatt Regency London The Churchill

Hyatt Regency London The Churchill
5.0 star property
London City Centre
9.0 out of 10, Wonderful, (1002)
"Great location. Delicious breakfast. "
United Kingdom
Jen
$339 nightly
The price is $406
Jan 10 - Jan 11, 2026
Total with taxes and fees
Hyatt Regency London The Churchill
Egyptian cotton sheets, premium bedding, minibar, in-room safe
Aethos London Shoreditch

Aethos London Shoreditch

Aethos London Shoreditch
5.0 star property
London City Centre
9.0 out of 10, Wonderful, (1002)
"Great Staff and impeccable accommodation!"
United Kingdom
Rory
$226 nightly
The price is $272
Jan 11 - Jan 12, 2026
Total with taxes and fees
Aethos London Shoreditch
Indoor pool, open 6:00 AM to 10:00 PM, sun loungers
The Langham, London

The Langham, London

The Langham, London
5.0 star property
London City Centre
9.6 out of 10, Exceptional, (1006)
"Lovely hotel, wonderful staff!"
United Kingdom
Andrew
$569 nightly
The price is $682
Jan 16 - Jan 17, 2026
Total with taxes and fees
The Langham, London
Exterior
InterContinental London Park Lane by IHG

InterContinental London Park Lane by IHG

InterContinental London Park Lane by IHG
5.0 star property
London City Centre
9.0 out of 10, Wonderful, (1001)
"Great location and friendly staff!"
United States
Debbie
$307 nightly
The price is $368
Jan 11 - Jan 12, 2026
Total with taxes and fees
InterContinental London Park Lane by IHG
2 bars/lounges
The BoTree

The BoTree

The BoTree
5.0 star property
London City Centre
9.4 out of 10, Exceptional, (304)
"Very nice hotel. Clean. Friendly staff. Great location "
United States
Marios
$397 nightly
The price is $477
Dec 21 - Dec 22
Total with taxes and fees
The BoTree
Rooftop terrace
The Londoner

The Londoner

The Londoner
5.0 star property
London City Centre
9.4 out of 10, Exceptional, (1006)
"Excellent hotel with an excellent location"
United States
Pini
$463 nightly
The price is $556
Jan 4 - Jan 5, 2026
Total with taxes and fees
The Londoner
City view from property
Montcalm Royal London House, London City

Montcalm Royal London House, London City

Montcalm Royal London House, London City
5.0 star property
London City Centre
8.6 out of 10, Excellent, (1013)
"Excellent stay, lovely staff, perfect location "
United Kingdom
Ami
$208 nightly
The price is $250
Dec 24 - Dec 25
Total with taxes and fees
Montcalm Royal London House, London City
Exterior
Nobu London Portman Square

Nobu London Portman Square

Nobu London Portman Square
5.0 star property
London City Centre
9.0 out of 10, Wonderful, (411)
"Staff were amazing and very helpful"
United Kingdom
Akiel
$403 nightly
The price is $484
Dec 24 - Dec 25
Total with taxes and fees
Nobu London Portman Square
Suite, 2 Bedrooms, Terrace | Egyptian cotton sheets, premium bedding, in-room safe, desk
The May Fair, A Radisson Collection Hotel, Mayfair London

The May Fair, A Radisson Collection Hotel, Mayfair London

The May Fair, A Radisson Collection Hotel, Mayfair London
5.0 star property
London City Centre
8.8 out of 10, Excellent, (1001)
"Room was clean and well equipped. Great location and staff, very pleasant, helpful and efficient."
United Kingdom
Sharon
$318 nightly
The price is $381
Jan 11 - Jan 12, 2026
Total with taxes and fees
The May Fair, A Radisson Collection Hotel, Mayfair London
Bar (on property)
Middle Eight - Covent Garden - Preferred Hotels and Resorts

Middle Eight - Covent Garden - Preferred Hotels and Resorts

Middle Eight - Covent Garden - Preferred Hotels and Resorts
5.0 star property
London City Centre
9.4 out of 10, Exceptional, (1462)
"Great staff and a great vibe in the best location in Covent Garden"
United States
Keith
$224 nightly
The price is $269
Jan 4 - Jan 5, 2026
Total with taxes and fees
Middle Eight - Covent Garden - Preferred Hotels and Resorts
2 bars/lounges, cocktail bar, lobby lounge
The Megaro Hotel - Kings Cross St Pancras, London

The Megaro Hotel - Kings Cross St Pancras, London

The Megaro Hotel - Kings Cross St Pancras, London
5.0 star property
London City Centre
9.0 out of 10, Wonderful, (1008)
"Great staff, cool decor, comfortable room. "
United States
Mark
$225 nightly
The price is $271
Jan 11 - Jan 12, 2026
Total with taxes and fees
The Megaro Hotel - Kings Cross St Pancras, London
Reception
Radisson Blu Hotel, London Leicester Square

Radisson Blu Hotel, London Leicester Square

Radisson Blu Hotel, London Leicester Square
5.0 star property
London City Centre
8.8 out of 10, Excellent, (1005)
"Lobby is beautiful, room is a little dated, but the amenities are delightful"
United States
Lisa
$201 nightly
The price is $241
Jan 11 - Jan 12, 2026
Total with taxes and fees
Radisson Blu Hotel, London Leicester Square
Meeting facility
St. Pancras London, Autograph Collection ®

St. Pancras London, Autograph Collection ®

St. Pancras London, Autograph Collection ®
5.0 star property
London City Centre
8.4 out of 10, Very Good, (1004)
"It was one of the best stays in a hotel I’ve ever had. "
United Kingdom
Patrick
$300 nightly
The price is $357
Dec 23 - Dec 24
Total with taxes and fees
St. Pancras London, Autograph Collection ®
Lobby
Montcalm Brewery, London City

Montcalm Brewery, London City

Montcalm Brewery, London City
5.0 star property
London City Centre
8.0 out of 10, Very Good, (1019)
"Great welcome, lovely building and great location "
United Kingdom
Paul
$140 nightly
The price is $168
Jan 4 - Jan 5, 2026
Total with taxes and fees
Montcalm Brewery, London City
Exterior
Mandarin Oriental Hyde Park, London

Mandarin Oriental Hyde Park, London

Mandarin Oriental Hyde Park, London
5.0 star property
London City Centre
8.8 out of 10, Excellent, (249)
"Immaculate in every way! Well done, from check in to the suites amenities, the lounge, service, right down to the nightly turndown surprises - an absolute must stay! "
Canada
Levi
$947 nightly
The price is $1,137
Jan 7 - Jan 8, 2026
Total with taxes and fees
Mandarin Oriental Hyde Park, London
2 bars/lounges
Rosewood London

Rosewood London

Rosewood London
5.0 star property
London City Centre
9.4 out of 10, Exceptional, (1004)
"Great property "
United States
Manuel Vincent
$616 nightly
The price is $740
Jan 12 - Jan 13, 2026
Total with taxes and fees
Rosewood London
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Explore similar 4-star hotels

Many 4-star hotels have the same amenities as 5-star hotels. See all 4-star hotels in Isleworth.
Strand Palace Hotel

Strand Palace Hotel

372 The Strand London England
$145 nightly
The price is $175 total per night from Jan 11 to Jan 12
$175 total
Jan 11 - Jan 12, 2026
Total with taxes and fees
8.8/10 Excellent! (4,731 reviews)
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about Isleworth

Tucked along the Thames, this historic riverside town offers peaceful walks past Syon House's magnificent gardens and the charming Old Isleworth pubs. Catch a rugby match at nearby Twickenham Stadium or explore the London Museum of Water and Steam where Victorian pumping engines still operate.

See all hotels in Isleworth
Osterley House, Osterley Park, Middlesex
Photo by Maxwell Hamilton
Open Photo by Maxwell Hamilton

Top Isleworth Hotel Reviews

Royal Garden Hotel

Royal Garden Hotel

10/10 Excellent
"Every thing was perfect food "
Timothy 1-night trip
Posted 3 days ago
Royal Garden Hotel
Sea Containers London

Sea Containers London

10/10 Excellent
"Overall experience was great,very helpful & friendly.Excellent hospitality!But keep in mind,they will charge the “accommodation service” after check out but was never mentioned when you check in or out,keep an eye on this charge from your bank.Needed to mention,Will, from the guest engagement team,for this charge,he acted with quick and efficient response after I emailed him.He was so helpful & willing to do the adjustment for this un-notice charge PROMPTLY!Really save my time of worrying when am I gonna get the money back.In all,their service was excellent,check in & out was great & smooth, even their porter was very polite & helpful.I feel really welcome & warm by their excellent customer service. Also their bedding was amazingly comfortable.Definitely gave us a good rest after a long day of walking.Spacious bathroom but the bath tub was a bit too high,my friends & I were having difficulty to go in & out.Need to be very careful & cautious or else will slip easily.A small point out to the housekeeping team or the management team,since I booked my room with 3 guests, we would assumed all the supplies should able to accommodate for 3 people but not 2 or 1,ex:bath towels & slippers only 2,the hygiene & dental care set only 1 & etc,with all these missing necessities when we request extra they delivered with more quantity which is a plus. I mean being marked as a 5 stars hotel I think working on this minor facility service with attention would help outshine their rating."
Ching 4-night trip
Posted 8 days ago
Sea Containers London

Find out more about Isleworth

Ready to experience the next standard in luxury? We know you're thinking about it. Add an extra layer of enjoyment on your next trip to Isleworth by treating yourself to the best of the best when it comes to lodging. It's an ideal combination. There's no reason to delay a getaway to Isleworth any longer. You'll join the multitudes of vacationers who have made Isleworth so fashionable in the last few seasons. You can also expect excellent customer service from these hotels, so get ready to kick back and indulge. Don't wait any longer. Book one of Expedia's luxurious 5-star hotels in Isleworth and get ready to be pampered like never before.

Book the Best Isleworth 5-Star Hotels

You'll have a wonderful time at one of these 5-star hotels. Spa treatments, delicious meals, and one-on-one attention are all waiting for you. You're sure to find exactly the accommodation you need. You can also expect excellent customer service from these hotels, so get ready for a wonderful adventure. How do you want to relax? A concierge to help you suggest the next attraction to visit? A Swedish massage to help your cares fall away? Fluffy down pillows, delectable chocolate desserts, and even space for your family pet in some cases...these hotels will leave you amazed. Want to see for yourself? Explore our listings and pick the perfect accommodation for your needs.

Can't wait to get outside? We've got you covered. From doing a bit of shopping to embracing the great outdoors, you'll never be bored on this retreat. No matter what's on your agenda, the 5-star hotels in Isleworth are waiting for you to relax after an exciting day.

Make Your Escape

The results are in, and Isleworth 5-star hotels are the place to be when you book your next vacation. If you've been dreaming about a vacation set here, then go ahead and book it. Your great getaway is just a mouse-click away -- Expedia can help you land a great deal on accommodation. Opt for one of Expedia's Isleworth 5-star hotels today and soothe yourself in total tranquility tomorrow.

Frequently asked questions

What are the best 5-star hotels in Isleworth?
According to Expedia traveler reviews, The Chelsea Harbour Hotel and Spa, The Bentley London and Cheval Gloucester Park are among the best 5-star hotels in Isleworth. Featuring top-quality amenities and unmatchable service, you'll enjoy an indulgent and memorable stay.
How much does it cost to stay in a 5-star hotel in Isleworth?
How much you pay for a 5-star hotel in Isleworth depends on factors like when you plan to travel and the length of your break. A top tip for bagging an awesome deal? Use our pricing filters to compare all of the available hotels for your preferred dates.

  • Search for the lowest price per night from $139

What makes a hotel 5 stars in Isleworth?
Exceptional guest service is the hallmark of every 5-star hotel in Isleworth. From the moment you arrive, staff attend to your every whim, whether arranging valet parking or providing a turn-down service. On top of that, hotels must offer upscale conveniences to qualify for a 5-star rating. These can include deluxe baths, spa facilities, pools, gourmet kitchens and knowledgeable concierge.

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