Title: Visit Carlisle: 2026 Travel Guide for Carlisle, South Carolina | Expedia.com

[Hotels in Carlisle](https://expedia.com/Carlisle-Hotels.d3000455877.Travel-Guide-Hotels)[Vacation Rentals in Carlisle](https://expedia.com/Carlisle-Vacation-Rentals.d3000455877.Travel-Guide-VacationRentals)[Flights to Carlisle](https://expedia.com/Cheap-Flights-To-Carlisle.d3000455877.Travel-Guide-Flights)[Car Rentals in Carlisle](https://expedia.com/Car-Rentals-In-Carlisle.d3000455877.Car-Rental-Guide)[Carlisle Vacation Packages](https://expedia.com/Carlisle.d3000455877.Destination-Travel-Guides)

# Carlisle, SC

## Travel Guide

## Visit Carlisle

- Carlisle Hotel Deals
- Vacation Rentals in Carlisle

![A Taste of Southern Comfort](https://images.trvl-media.com/lodging/97000000/96720000/96717300/96717290/9704f243_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

A Taste of Southern Comfort

 Carlisle SC

Stay at this vacation home in Carlisle. Enjoy a fitness center, laundry facilities, and patios.

9.6/10 Exceptional! (4 reviews)

Welcome to SC

This was my first opportunity to live in SC and everything was great and I wanted for nothing, I would recommend this house if you want tranquility in the evening

Reviewed on Jun 28, 2025

[Get rates](https://expedia.com/Hotel-Search?startDate=4%2F15%2F2026&endDate=4%2F16%2F2026&selected=96717290&PinnedHotelID=96717290&HadPinnedHotel=true&regionId=3000455877)

[](https://expedia.com/Hotel-Search?startDate=4%2F15%2F2026&endDate=4%2F16%2F2026&selected=96717290&PinnedHotelID=96717290&HadPinnedHotel=true&regionId=3000455877)

![Quality Inn Clinton - Laurens I-26](https://images.trvl-media.com/lodging/1000000/30000/26900/26875/54b1a852_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Quality Inn Clinton - Laurens I-26

105 Trade St Clinton SC

$58 nightly

$65 total

Apr 28 - Apr 29

Total with taxes and fees

Book a stay at this business-friendly hotel in Clinton. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff in our reviews. ...

7.4/10 Good! (539 reviews)

The particular room I had was spotless, clean and without any fragrances. The bed and sheets and pillows appeared to be almost new and very, very comfortable.

Reviewed on Mar 21, 2026

[](https://expedia.com/Hotel-Search?startDate=4%2F28%2F2026&endDate=4%2F29%2F2026&selected=26875&PinnedHotelID=26875&HadPinnedHotel=true&regionId=3000455877)

![Holiday Inn Express & Suites Newberry by IHG](https://images.trvl-media.com/lodging/3000000/2810000/2803700/2803681/d098e4c5_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Holiday Inn Express & Suites Newberry by IHG

121 Truman Ave Newberry SC

$123 nightly

$133 total

Apr 26 - Apr 27

Total with taxes and fees

Book a stay at this business-friendly hotel in Newberry. Enjoy free breakfast, free WiFi, and free parking. Our guests praise the helpful staff and the clean ...

9/10 Wonderful! (665 reviews)

Clean room, great breakfast, and convenient parking!

Reviewed on Apr 1, 2026

[](https://expedia.com/Hotel-Search?startDate=4%2F26%2F2026&endDate=4%2F27%2F2026&selected=2803681&PinnedHotelID=2803681&HadPinnedHotel=true&regionId=3000455877)

[See all 54 properties in Carlisle](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&startDate=4%2F2%2F2026&endDate=4%2F3%2F2026&regionId=3000455877)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

![A Taste of Southern Comfort](https://images.trvl-media.com/lodging/97000000/96720000/96717300/96717290/9704f243_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

A Taste of Southern Comfort

 Carlisle SC

Stay at this vacation home in Carlisle. Enjoy a fitness center, laundry facilities, and patios.

9.6/10 Exceptional! (4 reviews)

Welcome to SC

This was my first opportunity to live in SC and everything was great and I wanted for nothing, I would recommend this house if you want tranquility in the evening

Reviewed on Jun 28, 2025

[](https://expedia.com/Carlisle-Hotels-A-Taste-Of-Southern-Comfort.h96717290.Hotel-Information)

![Large late1800's home within walking distance to Opera House and downtown.](https://images.trvl-media.com/lodging/96000000/95130000/95125900/95125824/6400922f_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

Large late1800's home within walking distance to Opera House and downtown.

 Newberry SC

Stay at this vacation home in Newberry. Enjoy free WiFi, a garden, and laundry facilities. Popular attractions The Ritz Theater and Main Street Historic District ...

10/10 Exceptional! (43 reviews)

Wonderful experience

Reviewed on Mar 29, 2026

[](https://expedia.com/Newberry-Hotels-Large-Late1800s-Home-Within-Walking-Distance-To-Opera-House-And-Downtown.h95125824.Hotel-Information)

![1800’s Cabin with Hot Tub, Pet Friendly](https://images.trvl-media.com/lodging/92000000/91200000/91195900/91195817/w1169h772x0y1-59c75806_y.jpg?impolicy=resizecrop&rw=340&ch=150)

### 

1800’s Cabin with Hot Tub, Pet Friendly

 Rock Hill SC

Stay at this cabin in Rock Hill. Enjoy free WiFi, patios, and an in-room coffeemaker. Popular attractions Historic Brattonsville and Rock Hill Sports & Event ...

9.8/10 Exceptional! (22 reviews)

Cabin was clean & fun. Needs a nice knife set, extra light bulbs, more & better towels.Enjoyed our stay!

Reviewed on Feb 20, 2026

[](https://expedia.com/Rock-Hill-Hotels-1800s-Cabin-With-Hot-Tub.h91195817.Hotel-Information)

[See all properties in Carlisle](https://expedia.com/Hotel-Search?rfrrid=TG.LP.Hotels.DestinationExperience&regionId=3000455877&sort=VACATION_RENTAL)

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

## Check Carlisle hotel availability

[Tonight

](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true&regionId=3000455877&startDate=2026-04-01&endDate=2026-04-02)[Apr 1 - Apr 2](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true&regionId=3000455877&startDate=2026-04-01&endDate=2026-04-02)

[Tomorrow night

](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true&regionId=3000455877&startDate=2026-04-02&endDate=2026-04-03)[Apr 2 - Apr 3](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true&regionId=3000455877&startDate=2026-04-02&endDate=2026-04-03)

[This weekend

](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true&regionId=3000455877&startDate=4%2F3%2F2026&endDate=4%2F5%2F2026)[Apr 3 - Apr 5](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true&regionId=3000455877&startDate=4%2F3%2F2026&endDate=4%2F5%2F2026)

[Next weekend

](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true&regionId=3000455877&startDate=4%2F10%2F2026&endDate=4%2F12%2F2026)[Apr 10 - Apr 12](https://expedia.com/Hotel-Search?rfrrid=TG.LP.CheckPrices.DestinationExperience&adults=2&openPlayBack=true&regionId=3000455877&startDate=4%2F10%2F2026&endDate=4%2F12%2F2026)

## Cities near Carlisle

![sky and clouds sunset landscape over york south carolina](https://images.trvl-media.com/place/7209/e169d0fe-87c0-4252-bdd4-8ab1f4633ccf.jpg?impolicy=fcrop&w=512&h=288&q=medium)

### Chester

![architecture and buildings in union south carolina](https://images.trvl-media.com/place/56013/55ab68bf-0682-4a3a-ac49-dcbb669c8866.jpg?impolicy=fcrop&w=512&h=288&q=medium)

### Union

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- [Chester County Hotels ](https://www.expedia.com/Destinations-In-Chester-County.d553248635976434043.Hotel-Destinations)
- [Marriott Hotels & Resorts in Chester ](https://www.expedia.com/Chester-Hotels-Marriott-Hotels-Resorts.0-0-d7209--bMarriottHotelsResorts.Travel-Guide-Filter-Hotels)
- [5 Star Hotels in Chester ](https://www.expedia.com/5Star-Chester-Hotels.s50-0-d7209.Travel-Guide-Filter-Hotels)
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- [Hotels near Chester County Historical Society Museum and Archives ](https://www.expedia.com/Chester-County-Historical-Society-Museum-And-Archives-Hotels.0-l553248621560906806-0.Travel-Guide-Filter-Hotels)
- [Monticello Hotels ](https://www.expedia.com/Monticello-Hotels.d553248635975871782.Travel-Guide-Hotels)
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- [Blackstock Hotels ](https://www.expedia.com/Blackstock-Hotels.d3000353090.Travel-Guide-Hotels)
- [B&B in Blackstock ](https://www.expedia.com/Blackstock-Bed-And-Breakfast.d3000353090-aaBedAndBreakfast.Travel-Guide-Accommodation)
- [Jonesville Hotels ](https://www.expedia.com/Jonesville-Hotels.d553248634999439778.Travel-Guide-Hotels)
- [Hotels near Musgrove Mill State Historic Site ](https://www.expedia.com/Musgrove-Mill-State-Historic-Site-Hotels.0-l553248621532656795-0.Travel-Guide-Filter-Hotels)
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- [4 Star Hotels in Pomaria ](https://www.expedia.com/4Star-Pomaria-Hotels.s40-0-d3000456053.Travel-Guide-Filter-Hotels)
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- [Hotels near Newberry College ](https://www.expedia.com/Newberry-College-Hotels.0-l650066027630927872-0.Travel-Guide-Filter-Hotels)

- [Flights to Whitmire ](https://www.expedia.com/Cheap-Flights-To-Whitmire.d3000456164.Travel-Guide-Flights)
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- [Flights to Union ](https://www.expedia.com/Cheap-Flights-To-Union.d56013.Travel-Guide-Flights)
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- [Flights from Jonesville ](https://www.expedia.com/lp/flights/553248634999439778/flights-from-jonesville)
- [Flights to Pomaria ](https://www.expedia.com/Cheap-Flights-To-Pomaria.d3000456053.Travel-Guide-Flights)

- [Visit Whitmire ](https://www.expedia.com/Whitmire.dx3000456164)
- [South Carolina Bottle Museum ](https://www.expedia.com/South-Carolina-Bottle-Museum-Whitmire.d553248621532656796.Vacation-Attraction)
- [Rose Hill Plantation State Historic Site ](https://www.expedia.com/Rose-Hill-Plantation-State-Historic-Site-Union.d553248621532656797.Vacation-Attraction)
- [Visit Union ](https://www.expedia.com/Union.dx56013)
- [Veterans Memorial Park ](https://www.expedia.com/Veterans-Memorial-Park-Union.d553248621565028500.Vacation-Attraction)
- [Union Vacations ](https://www.expedia.com/Union.d56013.Destination-Travel-Guides)
- [West Towne Plaza ](https://www.expedia.com/West-Towne-Plaza-Union.d553248621565028501.Vacation-Attraction)
- [Visit Chester ](https://www.expedia.com/Chester.dx7209)
- [Chester Vacations ](https://www.expedia.com/Chester.d7209.Destination-Travel-Guides)
- [Cruse Vineyards and Winery ](https://www.expedia.com/Cruse-Vineyards-And-Winery-Chester.d553248621532657253.Vacation-Attraction)
- [Chester County Historical Society Museum and Archives ](https://www.expedia.com/Chester-County-Historical-Society-Museum-And-Archives-Chester.d553248621560906806.Vacation-Attraction)
- [Olde English District ](https://www.expedia.com/Olde-English-District-Chester.d553248621532657252.Vacation-Attraction)
- [Visit Blackstock ](https://www.expedia.com/Blackstock.dx3000353090)
- [Enoree River Vineyards and Winery ](https://www.expedia.com/Enoree-River-Vineyards-And-Winery-Newberry.d650065846682705920.Vacation-Attraction)
- [Blackstock Vacations ](https://www.expedia.com/Blackstock.d3000353090.Destination-Travel-Guides)
- [Visit Pomaria ](https://www.expedia.com/Pomaria.dx3000456053)
- [Musgrove Mill State Historic Site ](https://www.expedia.com/Musgrove-Mill-State-Historic-Site-Clinton.d553248621532656795.Vacation-Attraction)
- [Visit Cross Anchor ](https://www.expedia.com/Cross-Anchor.dx553248635519281641)
- [Visit Kinards ](https://www.expedia.com/Kinards.dx3000455994)
- [Visit McConnells ](https://www.expedia.com/McConnells.dx3000456026)
- [Visit Joanna ](https://www.expedia.com/Joanna.dx3000455986)

- [Car rentals near Whitmire ](https://www.expedia.com/Car-Rentals-In-Whitmire.d3000456164.Car-Rental-Guide)
- [Car rentals near Monarch Mill ](https://www.expedia.com/Car-Rentals-In-Monarch-Mill.d553248634999119412.Car-Rental-Guide)
- [Car rentals near Union ](https://www.expedia.com/Car-Rentals-In-Union.d56013.Car-Rental-Guide)
- [Car rentals in Avis 3901 Quebec St ](https://www.expedia.com/Avis-at-3901-Quebec-St-Denver-Colorado-USA.v56013.Car-Rental-Guide-Location)
- [Car rentals near Lockhart ](https://www.expedia.com/Car-Rentals-In-Lockhart.d553248634999092599.Car-Rental-Guide)
- [Car rentals near Gayle Mill ](https://www.expedia.com/Car-Rentals-In-Gayle-Mill.d553248634999106066.Car-Rental-Guide)
- [Car rentals near Buffalo ](https://www.expedia.com/Car-Rentals-In-Buffalo.d553248634999436658.Car-Rental-Guide)
- [Car rentals near Chester ](https://www.expedia.com/Car-Rentals-In-Chester.d7209.Car-Rental-Guide)
- [Priceless Car Rental Rental Cars in Chester ](https://www.expedia.com/Priceless-Car-Rental-Car-Rentals-In-Chester.d7209-c1060.Car-Rental-Guide-Suppliers)
- [Car rentals near Eureka Mill ](https://www.expedia.com/Car-Rentals-In-Eureka-Mill.d553248634999389690.Car-Rental-Guide)
- [Car rentals near Monticello ](https://www.expedia.com/Car-Rentals-In-Monticello.d553248635975871782.Car-Rental-Guide)
- [Car rentals near Lowrys ](https://www.expedia.com/Car-Rentals-In-Lowrys.d553248634999279045.Car-Rental-Guide)
- [Car rentals near Blackstock ](https://www.expedia.com/Car-Rentals-In-Blackstock.d3000353090.Car-Rental-Guide)
- [Car rentals near Pomaria ](https://www.expedia.com/Car-Rentals-In-Pomaria.d3000456053.Car-Rental-Guide)

- [Whitmire Vacation Rentals ](https://www.expedia.com/Whitmire-Vacation-Rentals.d3000456164.Travel-Guide-VacationRentals)
- [Union Vacation Rentals ](https://www.expedia.com/Union-Vacation-Rentals.d56013.Travel-Guide-VacationRentals)
- [Chester Vacation Rentals ](https://www.expedia.com/Chester-Vacation-Rentals.d7209.Travel-Guide-VacationRentals)

- Cities near Carlisle
- Places of interest

[Chester](https://expedia.com/Chester.dx7209)[Union](https://expedia.com/Union.dx56013)[Blackstock](https://expedia.com/Blackstock.dx3000353090)[Whitmire](https://expedia.com/Whitmire.dx3000456164)

- [Newberry Opera House ](https://expedia.com/Newberry-Opera-House-Newberry.d553248621532656685.Vacation-Attraction)
- [Newberry College ](https://expedia.com/Newberry-College-Newberry.d650066027630927872.Vacation-Attraction)
- [Veterans Memorial Park ](https://expedia.com/Veterans-Memorial-Park-Union.d553248621565028500.Vacation-Attraction)
- [Musgrove Mill State Historic Site ](https://expedia.com/Musgrove-Mill-State-Historic-Site-Clinton.d553248621532656795.Vacation-Attraction)
- [Cruse Vineyards and Winery ](https://expedia.com/Cruse-Vineyards-And-Winery-Chester.d553248621532657253.Vacation-Attraction)
- [Rose Hill Plantation State Historic Site ](https://expedia.com/Rose-Hill-Plantation-State-Historic-Site-Union.d553248621532656797.Vacation-Attraction)
- [Enoree River Vineyards and Winery ](https://expedia.com/Enoree-River-Vineyards-And-Winery-Newberry.d650065846682705920.Vacation-Attraction)
- [Chester County Historical Society Museum and Archives ](https://expedia.com/Chester-County-Historical-Society-Museum-And-Archives-Chester.d553248621560906806.Vacation-Attraction)
- [Historic Winnsboro Town Clock ](https://expedia.com/Historic-Winnsboro-Town-Clock-Winnsboro.d6319528.Vacation-Attraction)
- [Olde English District ](https://expedia.com/Olde-English-District-Chester.d553248621532657252.Vacation-Attraction)
- [Fairfield County Museum ](https://expedia.com/Fairfield-County-Museum-Winnsboro.d6319524.Vacation-Attraction)
- [Historic Brattonsville ](https://expedia.com/Historic-Brattonsville-South-Carolina.d553248621532657259.Vacation-Attraction)
- [South Carolina Bottle Museum ](https://expedia.com/South-Carolina-Bottle-Museum-Whitmire.d553248621532656796.Vacation-Attraction)
- [West Towne Plaza ](https://expedia.com/West-Towne-Plaza-Union.d553248621565028501.Vacation-Attraction)

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