Museum District Vacations from $213

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Your Houston Museum District Vacation

Houston Museum District is beckoning! Whatever type of break you have in mind, you can see and experience more of this neighborhood with a Houston Museum District vacation package. Start your trip to Houston Museum District by visiting nearby attractions such as Houston Zoo, Houston Natural Science Museum and Childrens Museum of Houston. Don't just dream it — turn it into a reality! Reserve your perfect Houston Museum District vacation with Expedia and get to where you're going your way.

The Latest Museum District Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Heritage Place Houston Brookhollow
Experience a First Class Stay - 2 BDRM
Hyatt Place Houston/Galleria
Dejs' Modern Retreat
Palace Inn Blue I-45 & College Ave

Where to stay in Museum District

Find the best Museum District areas and neighborhoods for the activities you enjoy most. Learn more about Museum District

Museum District Hotel Deals

Hotel Zaza Houston Museum District

Hotel Zaza Houston Museum District

4.5 out of 5
5701 Main Street Houston TX
Fully refundableReserve now, pay when you stay
$289 nightly
The price is $336 total per night from Nov 16 to Nov 17
$336 total
Nov 16 - Nov 17
Total with taxes and fees
9.2/10 Wonderful! (1,017 reviews)
"The hotel staff are friendly and helpful. Especially the car service people. The location is perfect if you are visiting Rice University. I have now stayed at this hotel twice. The only issue is the hotel is a a little tired. One elevator was not working. Water leaking on bathroom floor. Iron board ..."

Reviewed on Nov 13, 2026

Hotel Zaza Houston Museum District
Sentral Forme Houston

Sentral Forme Houston

4.5 out of 5
5501 La Branch Street Houston TX
Fully refundableReserve now, pay when you stay
$214 nightly
The price is $250 total per night from Dec 13 to Dec 14
$250 total
Dec 13 - Dec 14
Total with taxes and fees
9.2/10 Wonderful! (102 reviews)
"amazing!"

Reviewed on Nov 8, 2026

Sentral Forme Houston
DoubleTree by Hilton Hotel & Suites Houston by the Galleria

DoubleTree by Hilton Hotel & Suites Houston by the Galleria

4 out of 5
5353 Westheimer Rd Houston TX
Fully refundableReserve now, pay when you stay
$115 nightly
The price is $134 total per night from Nov 23 to Nov 24
$134 total
Nov 23 - Nov 24
Total with taxes and fees
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Museum District attractions

Things to do

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.