Medical District Vacations from $624

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Your Medical District Vacation

Our Medical District vacation packages are an easy and handy way to plan and book your next getaway. Discover the true character of this unique neighborhood without the burden of organizing everything yourself. When it's time to sightsee, you'll find plenty of top attractions nearby including Memphis Zoo, Orpheum Theatre and Sun Studio. Visit one, two (or even all!) during your trip to Medical District. Whatever your dream Medical District vacation looks like, you can turn it into reality with Expedia.

The Latest Medical District Vacation Packages

Price found within the past 48 hours. Click for updated prices.
Hu. Hotel
The Guest House at Graceland
Hotel Pontotoc
The Stallion
Hilton Garden Inn Memphis East Germantown, TN

Where to stay in Medical District

Find the best Medical District areas and neighborhoods for the activities you enjoy most. Learn more about Medical District

Medical District Hotel Deals

Motel 6 Memphis, TN - Downtown

Motel 6 Memphis, TN - Downtown

2 out of 5
210 S Pauline St Memphis TN
Fully refundableReserve now, pay when you stay
$48 nightly
The price is $59 total per night from Jul 21 to Jul 22
$59 total
Jul 21 - Jul 22
Total with taxes and fees
5.4/10 (1,001 reviews)
"I like the stay and I would like to stay again"

Reviewed on Jul 17, 2026

Motel 6 Memphis, TN - Downtown
Kings Inn

Kings Inn

2 out of 5
42 S Camilla St Memphis TN
Fully refundableReserve now, pay when you stay
$53 nightly
The price is $65 total per night from Jul 23 to Jul 24
$65 total
Jul 23 - Jul 24
Total with taxes and fees
6.4/10 (58 reviews)
"I won’t be coming back at all"

Reviewed on Jul 16, 2026

Kings Inn
Hu. Hotel

Hu. Hotel

3.5 out of 5
79 Madison Avenue Memphis TN
Fully refundableReserve now, pay when you stay
$93 nightly
The price is $112 total per night from Aug 3 to Aug 4
$112 total
Aug 3 - Aug 4
Total with taxes and fees
8.4/10 Very Good! (2,174 reviews)
"Very very dirty and not a good environment"

Reviewed on Jul 18, 2026

Hu. Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Medical District attractions

Things to do

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.