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Discover 356 Historic Southwest hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Hyatt House Rochester/Mayo Clinic Area

3.0 star property
9.2 out of 10, Wonderful, (965)
"The beds were extremely comfortable!"
$122 nightly
The price is $141
Aug 9 - Aug 10
Total includes taxes and fees
Hyatt House Rochester/Mayo Clinic Area

Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic

2.0 star property
8.0 out of 10, Very Good, (1001)
"It was quiet, easy to find and check in was fast."
$66 nightly
The price is $76
Jul 20 - Jul 21
Total includes taxes and fees
Microtel Inn & Suites by Wyndham Rochester North Mayo Clinic

AmericInn by Wyndham Rochester

2.0 star property
8.8 out of 10, Excellent, (1012)
"Very friendly staff."
$73 nightly
The price is $84
Aug 17 - Aug 18
Total includes taxes and fees
AmericInn by Wyndham Rochester

Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

3.0 star property
8.4 out of 10, Very Good, (1005)
"Best place to stay when visiting the Mayo Clinic "
$123 nightly
The price is $142
Jul 18 - Jul 19
Total includes taxes and fees
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area

Hilton Garden Inn Rochester Downtown, MN

3.0 star property
8.8 out of 10, Excellent, (784)
"Nice stay"
$118 nightly
The price is $136
Jul 27 - Jul 28
Total includes taxes and fees
Hilton Garden Inn Rochester Downtown, MN

Hotel Indigo Rochester – Mayo Clinic Area by IHG

3.5 star property
8.8 out of 10, Excellent, (791)
"Nice place will stay again"
$99 nightly
The price is $114
Aug 8 - Aug 9
Total includes taxes and fees
Hotel Indigo Rochester – Mayo Clinic Area by IHG

The Berkman

3.0 star property
9.6 out of 10, Exceptional, (315)
"Great hotel."
$129 nightly
The price is $148
Jul 19 - Jul 20
Total includes taxes and fees
The Berkman

Hampton Inn Rochester-South

2.5 star property
9.0 out of 10, Wonderful, (1001)
"Great place to stay!"
$89 nightly
The price is $102
Aug 9 - Aug 10
Total includes taxes and fees
Hampton Inn Rochester-South

Aspen Select

3.5 star property
8.6 out of 10, Excellent, (1004)
"Nice place and convenient to hospital "
$118 nightly
The price is $136
Jul 18 - Jul 19
Total includes taxes and fees
Aspen Select

TownePlace Suites by Marriott Rochester Mayo Clinic Area

3.0 star property
9.6 out of 10, Exceptional, (437)
"Our favorite place to stay when traveling to Mayo Clinic."
$109 nightly
The price is $125
Aug 8 - Aug 9
Total includes taxes and fees
TownePlace Suites by Marriott Rochester Mayo Clinic Area

America's Stay Inn Stewartville

2.5 star property
8.0 out of 10, Very Good, (375)
"The room was clean, the stay was pleasant."
$64 nightly
The price is $69
Aug 17 - Aug 18
Total includes taxes and fees
America's Stay Inn Stewartville

EVEN Hotel Rochester - Mayo Clinic Area by IHG

4.0 star property
9.4 out of 10, Exceptional, (850)
"The staff were friendly and so amazingly accommodating! "
$121 nightly
The price is $139
Jul 20 - Jul 21
Total includes taxes and fees
EVEN Hotel Rochester - Mayo Clinic Area by IHG

Kahler Grand Hotel

3.0 star property
8.2 out of 10, Very Good, (1452)
"Great stay!"
$119 nightly
The price is $138
Jul 18 - Jul 19
Total includes taxes and fees
Kahler Grand Hotel

Econo Lodge Mayo Clinic Area

2.0 star property
9.0 out of 10, Wonderful, (711)
"Nice, clean hotel! "
$61 nightly
The price is $70
Aug 10 - Aug 11
Total includes taxes and fees
Econo Lodge Mayo Clinic Area

Kahler Inn and Suites - Mayo Clinic Area

3.5 star property
7.8 out of 10, Good, (1369)
"Nice and clean; great breakfast included; very helpful and supportive staff; perfect location to Mayo Clinic buildings. "
$112 nightly
The price is $130
Jul 31 - Aug 1
Total includes taxes and fees
Kahler Inn and Suites - Mayo Clinic Area

Brentwood Inn & Suites

2.5 star property
8.6 out of 10, Excellent, (1001)
"I enjoyed my stay. Room was clean and the staff was helpful and friendly."
$125 nightly
The price is $144
Jul 18 - Jul 19
Total includes taxes and fees
Brentwood Inn & Suites

La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

3.0 star property
7.2 out of 10, Good, (1030)
"place was clean and quiet, kids pool was bonus"
$72 nightly
The price is $83
Jul 20 - Jul 21
Total includes taxes and fees
La Quinta Inn & Suites by Wyndham Rochester Mayo Clinic S

Holiday Inn Express Rochester South - Mayo Area by IHG

2.5 star property
8.8 out of 10, Excellent, (1000)
" Ice and convenient place to stay, very clean and comfortable "
$87 nightly
The price is $100
Aug 10 - Aug 11
Total includes taxes and fees
Holiday Inn Express Rochester South - Mayo Area by IHG

Super 8 by Wyndham Rochester Mayo Clinic Area

2.0 star property
7.8 out of 10, Good, (1002)
"Absolutely incredible service and place to stay. "
$54 nightly
The price is $63
Jul 31 - Aug 1
Total includes taxes and fees
Super 8 by Wyndham Rochester Mayo Clinic Area

Hampton Inn & Suites Rochester-North

2.5 star property
9.2 out of 10, Wonderful, (1000)
"A very nice place to stay! Very clean and quiet with an excellent breakfast!"
$106 nightly
The price is $122
Jul 27 - Jul 28
Total includes taxes and fees
Hampton Inn & Suites Rochester-North
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Where to stay in Historic Southwest

Find the best Historic Southwest areas and neighborhoods for the activities you enjoy most. Learn more about Historic Southwest
Learn more about Historic Southwest
Downtown Rochester map

Downtown Rochester

3 out of top 10 points of interest in this area

If you're spending some time in Downtown Rochester, Mayo Civic Center and Rochester Civic Theater are top sights worth seeing.

Kutzky Park map

Kutzky Park

While there might not be top attractions in Kutzky Park, you can explore the larger area and discover places like Soldiers Field Veterans Memorial and Mayo Civic Center.

Folwell map

Folwell

1 out of top 10 points of interest in this area

While there might not be top attractions in Folwell, you can explore the larger area and discover places like Soldiers Field Veterans Memorial and Apache Mall.

East Side Pioneers map

East Side Pioneers

If you're spending some time in East Side Pioneers, Rochester Art Center and Rochester Civic Theater are top sights worth seeing.

Slatterly Park map

Slatterly Park

Slatterly Park might not have many top sights, but Rochester Art Center and Soldiers Field Veterans Memorial are two attractions nearby that you can check out.

Frequently asked questions

What are the best hotels in Historic Southwest that travelers recommend?
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area is a highly regarded choice for travelers, boasting an excellent review score of 8.4. This hotel not only offers free breakfast options, including a delightful buffet on weekends, but also features an inviting indoor pool that is superb for families wanting to unwind after a day of adventure. The hot tub adds an extra touch of relaxation, making it an ideal retreat for those seeking comfort and convenience.
What are the best family hotels in Historic Southwest?
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area in Rochester, MN is an excellent choice for families seeking comfort and convenience. With an excellent review score of 8.4, this hotel is designed to cater to the needs of travelers with children.
What hotels in Historic Southwest offer free breakfast?
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area is a fantastic choice for travelers seeking comfort and convenience in Rochester, MN. This family-friendly hotel not only offers a complimentary breakfast, great for fueling up before a day of exploration, but also features an inviting indoor pool, ideal for a splash with the kids or a relaxing swim after a busy day.
What are the best budget hotels in Historic Southwest?
Centerstone Plaza Hotel Soldiers Field - Mayo Clinic Area is an excellent choice for budget-conscious travelers seeking comfort and convenience in Rochester, MN. Rated 8.4 by guests, this hotel offers a warm and friendly setting, superb for travelers.
Can I cancel my hotel reservation on Expedia?
Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline -- this is often within 24-48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our "Fully refundable property" filter during your search to find the right Historic Southwest hotel for you.
How can I save on a Historic Southwest hotel booking with Expedia?
One Key™ - Expedia's free travel rewards program - gives you instant access to perks and Member Prices on Historic Southwest hotels. Plus, you'll earn OneKeyCash™* on eligible bookings to use on future trips. Booking an Expedia hotel and flight package is another great way to save, where bundling can result in significant savings.

*OneKeyCash is not redeemable for cash and can only be used on Expedia, Hotels.com and Vrbo.
How much is the nightly rate at a Historic Southwest hotel?
Hotel prices in Historic Southwest often vary, but you can find a great deal from $69 on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates, and sort search results by "Price: low to high" for our cheapest rates.