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Find Resorts & Hotels with Spas in Southern Illinois, IL

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Top Southern Illinois Resorts & Hotels with Spas

Walker's Bluff Casino Resort

4.5 star property
Carterville
9.4 out of 10, Exceptional, (385)
"Great place!!"
United States
Jeff
$182 nightly
The price is $203
Nov 30 - Dec 1
Total with taxes and fees
Walker's Bluff Casino Resort

1895 Washington Hotel

3.0 star property
Paducah
9.2 out of 10, Wonderful, (386)
"The room was perfect! The history of the house and the ambiance was so nice! James was a perfect host and saw to all our needs! We will stay again, thank you James!"
United States
Randall
$57 nightly
The price is $67
Dec 8 - Dec 9
Total with taxes and fees
1895 Washington Hotel

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1004)
"It was right off the interstate with lots of restaurant options "
United States
Kelly
$95 nightly
The price is $107
Nov 30 - Dec 1
Total with taxes and fees
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Ameristar Casino Resort and Spa

4.5 star property
St. Charles
8.4 out of 10, Very Good, (1006)
"Beautiful hotel, spacious guestroom, comfortable beds, kind and helpful staff! "
United States
Heather
$157 nightly
The price is $184
Dec 7 - Dec 8
Total with taxes and fees
Ameristar Casino Resort and Spa

Arthur's Country Inn

2.5 star property
Arthur
8.4 out of 10, Very Good, (131)
"We loved this Inn it was a unique experience in comparison to modern hotels but definitely a nice change. "
United States
Latasha
$106 nightly
The price is $118
Nov 29 - Nov 30
Total with taxes and fees
Arthur's Country Inn

21C Museum Hotel St Louis

4.5 star property
Downtown West
9.0 out of 10, Wonderful, (1473)
"Great staff and clean room"
United States
Chris
$156 nightly
The price is $183
Dec 21 - Dec 22
Total with taxes and fees
21C Museum Hotel St Louis

Four Seasons Hotel St Louis

5.0 star property
Downtown St. Louis
9.4 out of 10, Exceptional, (1004)
"The staff was amazing. The bed was so comfortable. "
United States
Mary
$425 nightly
The price is $497
Nov 29 - Nov 30
Total with taxes and fees
Four Seasons Hotel St Louis

The Ritz-Carlton, St. Louis

5.0 star property
Clayton
9.2 out of 10, Wonderful, (551)
"Service is exceptional!!!"
United States
Jorge
$469 nightly
The price is $548
Nov 29 - Nov 30
Total with taxes and fees
The Ritz-Carlton, St. Louis
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Find out more about Southern Illinois

Top Southern Illinois attractions for a relaxing vacation

Southern Illinois is a hidden gem for travelers seeking rejuvenation and adventure. Start your journey at the stunning Giant City State Park, where you can enjoy hiking through scenic trails that weave past massive sandstone bluffs, perfect for a refreshing afternoon hike before indulging in spa treatments. Next, explore the vibrant town of Carbondale, where local boutiques and eateries offer a taste of the region’s charm, alongside a range of wellness-focused establishments. Don’t miss the Shawnee National Forest, where you can immerse yourself in nature with opportunities for rock climbing and horseback riding, then retreat to your hotel for a soothing massage. For those seeking relaxation, the Murphysboro area boasts quaint bed and breakfasts with spa services that create an intimate and luxurious experience. Lastly, visit the beautiful wineries along the Shawnee Hills Wine Trail, where you can sample exquisite local wines and unwind amidst breathtaking vineyard views. Consider staying in Carbondale or Murphysboro, where you’ll find hotels that cater to your every need, complete with top spas and personalized service, making for a truly pampered getaway.

Top Southern Illinois Hotel Reviews

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