A marshy landscape with water, trees, and a distant city skyline.

Ladys Island Vacations from $512

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The Latest Ladys Island Vacation Packages

Price found within the past 48 hours. Click for updated prices.
  • Jan 22 - Jan 25

    The Francis Marion Hotel + Flight

    Charleston Historic District
    3 nights
    4.0 star property
    9.0/10 - Wonderful (2,647 reviews)
    Roundtrip • Boston (BOS) - Charleston (CHS)
    BOS - CHS • Nonstop CHS - BOS • Nonstop
    $712
    $512
    per traveler
    found 1 day ago
    The Francis Marion Hotel
  • Dec 31 - Jan 5

    The Ryder Hotel + Flight

    Charleston Historic District
    5 nights
    3.5 star property
    8.8/10 - Excellent (1,263 reviews)
    "Great location to everything - cute little hotel"
    Reviewed November 9, 2026
    Roundtrip • Boston (BOS) - Charleston (CHS)
    BOS - CHS • Nonstop CHS - BOS • 1 stop
    $1,296
    $859
    per traveler
    found 1 day ago
    The Ryder Hotel
  • Dec 31 - Jan 5

    The Charleston Place + Flight

    Charleston Historic District
    5 nights
    5.0 star property
    9.6/10 - Exceptional (1,006 reviews)
    "What a beautiful property! It’s very expensive however, the rooms are spacious and beautifully appointed the lobby and restaurants and bar are also lovely! You cannot beat the location walking right out into everything Charleston has to offer!"
    Reviewed November 9, 2026
    Roundtrip • Boston (BOS) - Charleston (CHS)
    BOS - CHS • Nonstop CHS - BOS • 1 stop
    $3,121
    $2,238
    per traveler
    found 1 day ago
    The Charleston Place
  • Dec 19 - Dec 24

    Godley Manor + Flight

    Historic Downtown Savannah
    5 nights
    3.0 star property
    9.8/10 - Exceptional (605 reviews)
    "Perfect location, comfortable room and ammenities. Nice breakfast and staff. Thanks Beth for your hospitality!"
    Reviewed November 8, 2026
    Roundtrip • Boston (BOS) - Savannah (SAV)
    BOS - SAV • Nonstop SAV - BOS • Nonstop
    $1,297
    $946
    per traveler
    found 1 day ago
    Godley Manor
  • Dec 21 - Dec 26

    Thompson Savannah, by Hyatt + Flight

    Hitch Village - Fred Wessels Homes
    5 nights
    5.0 star property
    9.4/10 - Exceptional (1,007 reviews)
    Roundtrip • Boston (BOS) - Savannah (SAV)
    BOS - SAV • Nonstop SAV - BOS • 1 stop
    $1,102
    $813
    per traveler
    found 1 day ago
    Thompson Savannah, by Hyatt

Discover the most popular places to visit in Ladys Island

Ladys Island Hotel Deals

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.